Trust Region Policy Learning for Adaptive Drug Infusion with Communication Networks in Hypertensive Patients by Mai The Vu, Seong Han Kim, Ha Le Nhu Ngoc Thanh, Majid Roohi, Tuan Hai Nguyen

“…In the field of biomedical engineering, the issue of drug delivery constitutes a multifaceted and demanding endeavor for healthcare professionals. …”
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A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis by Tianjiao Deng, Xinyi Jing, Liuqi Shao, Yakun Wang, Congrui Fu, Hongxiao Yu, Xiaoyi Wang, Xue Zhao, Fanrao Kong, Yake Ji, Xiaochen Tian, Wei He, Shangyu Bi, Luo Shi, Hanqiao Wang, Fang Yuan, Sheng Wang

“…Here, the functional connectivity between two key medullary hubs: the nucleus tractus solitarius (NTS) and the preBötzinger complex (preBötC) are systematically investigated. …”
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CD73 Expression on Mesenchymal Stem Cells Dictates the Reparative Properties via Its Anti-Inflammatory Activity by Kezhe Tan, Hongtao Zhu, Jianfang Zhang, Weili Ouyang, Jianfeng Tang, Youming Zhang, Linlin Qiu, Xueqing Liu, Zhaoping Ding, Xiaoming Deng

“…Transplantation of two types of cells into mouse hearts after myocardial infarction (MI) revealed that the CD73high pMSC preferentially brought about structural and functional repair in comparison to the PBS control and CD73low pMSC. …”
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Advancing the Frontiers of Deep Learning for Low-Dose 3D Cone-Beam CT Reconstruction by Ander Biguri, Subhadip Mukherjee, Xuzhi Zhao, Xi Liu, Xinyi Wang, Rui Yang, Yi Du, Yahui Peng, Mikael Brudfors, Mark Graham, Hyungon Ryu, Oliver Kutter, Andreas Hauptmann, Mustafa Al-Rubaye, Miika T. Nieminen, Mikael A. K. Brix, Austin Yunker, Rajkumar Kettimuthu, John C. Roeske, Sasidhar Alavala, Subrahmanyam Gorthi, Carola-Bibiane Schonlieb

“…The classical variational approach for CT reconstruction minimizes an energy functional using an appropriate iterative algorithm. …”
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Dynamic switching between brain networks predicts creative ability by Qunlin Chen, Yoed N. Kenett, Zaixu Cui, Hikaru Takeuchi, Andreas Fink, Mathias Benedek, Daniel C. Zeitlen, Kaixiang Zhuang, James Lloyd-Cox, Ryuta Kawashima, Jiang Qiu, Roger E. Beaty

“…Abstract Creativity is hypothesized to arise from a mental state which balances spontaneous thought and cognitive control, corresponding to functional connectivity between the brain’s Default Mode (DMN) and Executive Control (ECN) Networks. …”
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Biochemical and structural characterization of a reactive intermediate deaminase A homolog from Streptococcus sanguinis by Alexa B. Benedict, Adreana I. Aquino, Brandi A. Buckner, Swarmistha Devi Aribam, Chhandosee Ganguly, Leonard M. Thomas, Philip Bourne, Rakhi Rajan, Diana M. Downs, Vijayakumar Somalinga

“…Furthermore, L-amino acid oxidase assays showed SsRidA has significant activity against several with imino-amino acids similar to the S. enterica RidA. In addition, functional complementation analysis found that SsRidA restored growth of S. enterica ridA mutant in minimal media constituted to increase 2AA stress in the cell. …”
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Analysis of the Possibility of Using 3D Printing for Emergency Replacement of Damaged Elements in the Marine Industry by Krzysztof Jasiński, Lech Murawski, Marcin Kluczyk, Jarosław Wierzchowski, Marek Chodnicki, Krzysztof Lipiński, Adam Szeleziński

“…The authors’ research interests include the application of incremental and hybrid methods for the production of new, fully functional parts that constitute equipment for ships and yachts. …”
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Three-dimensional finite element analysis of implant positioning protocols in the maxillary sinus region for zygomatic bone implantation by LI Jing, LI Chenxi, PEI Pei, CHEN Cheng, GONG Zhongcheng

“…[Objective:] To compare the distribution characteristics of biochemical stress on two techniques of zygomatic implant (ZI), sinus slot (SS) and extra sinus (ES), in combination with conventional implants respectively, and to provide theoretical basis for functional restoration of severe atrophic maxilla. [Methods:] Finite element analysis (FEA) models were constituted based on high-resolution computed tomography (CT) scanning data of a patient. …”
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Knockout of cyclin-dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice by Alexandra V Bruter, Ekaterina A Varlamova, Nina I Stavskaya, Zoia G Antysheva, Vasily N Manskikh, Anna V Tvorogova, Diana S Korshunova, Alvina I Khamidullina, Marina V Utkina, Viktor P Bogdanov, Iuliia P Baikova, Alyona I Nikiforova, Eugene A Albert, Denis O Maksimov, Jing Li, Mengqian Chen, Gary P Schools, Alexey V Feoktistov, Alexander A Shtil, Igor B Roninson, Vladislav A Mogila, Yulia Y Silaeva, Victor V Tatarskiy

“…We have generated mice with the systemic inducible Cdk8 knockout on the background of Cdk19 constitutive knockout. Cdk8/19 double knockout (iDKO) males, but not single Cdk8 or Cdk19 KO, had an atrophic reproductive system and were infertile. …”
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Optimization of a chemical recycling process for epoxy-amine thermosets and their carbon fiber reinforced composites using a design of experiments approach by Valeria De Fabritiis, Leonardo Matta, Gianmarco Griffini, Stefano Turri

“…As a result of this validation step, a functional oligomeric organic fraction could be recovered, together with intact and clean recycled CFs able to preserve >95 % of their pristine mechanical properties. …”
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Loss of VHL-mediated pRb regulation promotes clear cell renal cell carcinoma by Mercy Akuma, Minjun Kim, Chenxuan Zhu, Ellis Wiljer, Antoine Gaudreau-Lapierre, Leshan D. Patterson, Lars Egevad, Simon Tanguay, Laura Trinkle-Mulcahy, William L. Stanford, Yasser Riazalhosseini, Ryan C. Russell

“…VHL loss in ccRCC leads to constitutive stabilization of E3 ligase substrates, including hypoxia inducible factor α (HIFα). …”
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Enabling beam-scanning antenna technologies for terahertz wireless systems: A review by Dongze Zheng, Geng-Bo Wu, Zhi Hao Jiang, Wei Hong, Chi Hou Chan, Ke Wu

“…While producing a scannable highly-directive antenna beam proves to be indispensable in the period of microwaves, the significance of such functionality is more critical in the THz era, considering that THz waves have more intractable challenges such as the severity of free-space propagation losses, the susceptibility to atmospheric environments, and the unavailability of efficient signal sources. …”
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Elevated levels of exogenous prolactin promote inflammation at the maternal-fetal interface via the JAK2/STAT5B signaling axis by Alycia Williams, Daniel J. Hossack, Nia Thompson, Yul Eum Sim, Cristina Wilson, Viviane Schuch, Tiffany Hailstorks, Rana Chakraborty, Erica L. Johnson, Erica L. Johnson, Erica L. Johnson

“…These results highlight the inflammatory roles of elevated PRL at the maternal-fetal interface, underscoring the need for further mechanistic studies to elucidate its functions in pregnancy.…”
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Ya That Somdun improves hepatic steatosis in hyperlipidemic rats by Suchittra Samuhasaneeto, Gorawit Yusakul, Chuchard Punsawad, Kingkan Bunluepuech

“…Some of the herbs constituting YTS have antihyperlipidemic and anti-obesity activities. …”
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Opracowanie profilu kompetencji menedżera ds. internacjonalizacji branży rolno-spożywczej by Iwona Kacak, Katarzyna Skoczylas, Elif Yücel, Özge Güler

“…Agriculture, just like any other economy sector, is functioning and growing under the conditions formed mainly by the market and economic laws. …”
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Bioinformatics reveal macrophages marker genes signature in breast cancer to predict prognosis by Ying Li, Xin Zhao, Qiang Liu, Yujie Liu

“…Immunotherapy has become a promising means to cure breast cancer. As constitutes of immune microenvironment of breast cancer, macrophages exert complicated functions in the tumour development and treatment. …”
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Research on Mechanical Performance of Porous Asphalt Mixture with High-Viscosity Modified Asphalt by Wei Chen, Zhengchao Zhang, Jincheng Wei, Xiaomeng Zhang, Chenghua Gan, Wenjian Wang, Yuxuan Sun

“…The proposed high-viscoelastic asphalt formulation meets the technical requirements for functional drainage asphalt mixtures while providing material-level support for implementing sponge city initiatives.…”
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The state of NOergic homeostasis in experimental autoimmune glomerulonephritis against the background of the use of cell-free cryopreserved biological agents by F.V. Hladkykh, T.I. Lіadova

“…NO is a vital molecule involved in a number of signaling functions in the kidney and can be released by a variety of kidney cells, including endothelial and mesangial cells as well as podocytes. …”
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Approaches to modulate buffalo gut microbiome for efficient feed utilization and reduced environmental pollution by Vijit Dey, Puran C. Lailer, Tirtha K. Datta

“…Among sequences with valid family names, Acidaminococcaceae was most predominant, constituting 1.5 to 4.7% of sequences. Similarly, Acidaminococcus was most predominant at the genus level among sequences with valid genus names, constituting 1.4 to 4.1% of total bacterial sequences. …”
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The Community Structure of Aerobic Anoxygenic Photosynthetic Bacteria in Biocrusts on Tropical Coral Islands and Their Application in Ecological Restoration, South China Sea by Jing Wen, Zhimao Mai, Jie Li, Lin Wang, Si Zhang

“…Biological soil crusts (referred to as biocrusts) constitute prominent components within the ecosystem of tropical coral islands in the South China Sea, covering approximately 6.25% of the island’s terrestrial surface. …”
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