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2701
Decoding estrogen receptor and GPER biology: structural insights and therapeutic advances in ERα−positive breast cancer
Published 2025-06-01“…This review explores the structural and functional intricacies of ERα, the impact of ESR1 mutations on its ligand-binding domain (ERα−LBD) and their contribution to ET resistance, and the role of GPER-mediated signaling in ERα−positive BC. …”
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2702
Predictive features analysis and nomogram construction for predicting depression in elderly patients
Published 2025-08-01“…The Comprehensive Geriatric Assessment (CGA), a multidimensional approach, evaluates medical, psychological, and functional capacities to identify highrisk individuals and may be correlated with depression in the elderly.MethodsFrom 2021 to 2023, a total of 219 geriatric patients were recruited. …”
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2703
Conflict between cattle ranching and the conservation of jaguar (Panthera onca) and puma (Puma concolor) in the Amazon arc of deforestation.
Published 2024-01-01“…Livestock predation constitutes the primary source of conflict between humans and large carnivores. …”
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2704
Ethics in Consumer Neuroscience: A Non-Exhaustive Presentation
Published 2025-04-01“…As Neuroscience approaches are increasingly accepted by Marketing and other social sciences, a sound and functional ethical foundation would help safe, fair, and fast advances rather than allow for abuses or constitute unnecessary impediments.…”
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2705
Revealing the larval anatomy of the hoverfly Sphaerophoria rueppellii (Wiedemann, 1820) (Diptera, Syrphidae) using micro-computed tomography
Published 2024-11-01“…This study constitutes a true anatomical atlas of the third instar larvae of S. rueppellii. …”
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2706
Information and Life: Towards a Biological Understanding of Informational Phenomena
Published 2008-07-01“…The variant in-formation spelling emphasizes that the cellular coupling among constitutive (proteomic), generative (genomic), and communicational (signaling) information genera produces a differentiated mode of existence, the living state, which is always in the making, perpetually in formation. …”
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2707
Petiveria alliacea and Caesalpinia spinosa extracts reduce the generation of cancer-associated fibroblasts in a 3D platform representative of the tumor microenvironment
Published 2025-07-01“…Conclusions We found that the two extracts interfere with circuits that drive tumor-fibroblast crosstalk, attenuating the phenotype and functional activities associated with CAFs in this TME model.…”
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2708
Interplay of intrinsic and synaptic conductances in the generation of high-frequency oscillations in interneuronal networks with irregular spiking.
Published 2014-05-01“…High-frequency oscillations (above 30 Hz) have been observed in sensory and higher-order brain areas, and are believed to constitute a general hallmark of functional neuronal activation. …”
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2709
Spatiotemporal Evolution and Complexity of Urban Networks in China, 1978–2019: An Enterprise Linkages Perspective
Published 2021-01-01“…There were more cities with headquarter-branches and active investment behaviors, which had strong influence and control over networks, playing their functions of “broker” and “transfer.”…”
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2710
Cultura de inteligencia y sociedad
Published 2022-09-01“…Abstract The doctrine largely identifies intelligence culture as a public awareness policy, which aims to improve society's understanding of the objectives and functions of the Intelligence Services. The common motivation is that all social actors become aware that they have an active role in safeguarding security, and that only the sum of efforts can guarantee security and the defense of shared democratic and constitutional values. …”
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2711
Characteristics of hand and foot soft tissue sarcomas: experience of one institution
Published 2024-04-01“…Soft tissue sarcomas of the distal extremities constitute an extremely rare heterogeneous group of malignant mesenchymal tissue tumors, and very few publications are available on this subject. …”
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2712
Features of the alpha-cell population organization in pancreas of spontaneously hypertensive rats (SHR)
Published 2017-08-01“…Alpha cells of pancreatic islets constitute the second largest population of pancreatic endocrinocytes, and the glucagon synthesized in them plays an important role in the regulation of glucose homeostasis. …”
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2713
Automatically generated language learning exercises for Finno-Ugric languages
Published 2023-12-01“… Morphologically rich languages always constitute a great challenge for language learners. …”
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2714
Analysis of the promoters involved in enterocin AS-48 expression.
Published 2014-01-01“…The production of and immunity towards AS-48 depend upon the coordinated expression of ten genes organized in two operons, as-48ABC (where genes encoding enzymes with processing, secretion, and immunity functions are adjacent to the structural as-48A gene) and as-48C1DD1EFGH. …”
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2715
The African Union and its regional economic communities confronted with coups d’état: between condemning and condoning
Published 2025-04-01“…Although African Union and its regional integration organizations are trapped in a delicate situation regarding their institutional and functional autonomy, they would at least save their legitimacy vis-à-vis the citizens of their member states if they firmly condemned all forms of coups d’état including constitutional or electoral ones. …”
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2716
Early rehabilitation interventions for global developmental delay in children: a narrative review
Published 2025-07-01“…Early action has a meaningful impact on the development of motor functions, cognitive abilities, social skills, language skills, and skills related to socialisation. …”
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2717
Detection of high-risk diseases in poultry feces through transfer learning
Published 2025-04-01“…Poultry farming industry constitutes a significant part of the global economy. …”
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2718
Anxiety, depression, and post-traumatic stress and associated risk factors among out-of-school girls in western Kenya.
Published 2025-01-01“…<h4>Conclusion</h4>Out-of-school girls constitute a vulnerable group with high levels of PTSD and suicide risk. …”
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2719
KrillDB: A de novo transcriptome database for the Antarctic krill (Euphausia superba).
Published 2017-01-01“…The genetics of Antarctic krill has long been of scientific interest for both for the analysis of population structure and analysis of functional genetics. However, the genetic resources available for the species are relatively modest. …”
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2720
THE ROLE OF SELF-MARKETING IN CREATING OPPORTUNITIES FOR ROMA EMPLOYMENT
Published 2024-07-01“…he role of different groups in society in the labour market is of vital importance for the functioning of a nation’s economy. Equal access to employment is a fundamental condition for tackling social exclusion and is closely linked to reducing and combating poverty. …”
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