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2341
Immune in myocardial ischemia/reperfusion injury: potential mechanisms and therapeutic strategies
Published 2025-05-01“…Multiple immune cells are present in the reperfusion area, executing specific functions and engaging in crosstalk during diverse stages, constituting a complex immune microenvironment involved in tissue repair and regeneration after MIRI. …”
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2342
RECOMMENDATIONS FOR THE CONSTRUCTION OF INFORMATION AND TELECOMMUNICATION NETWORKS BASED ON THE COMPARATIVE EVALUATION OF THEIR SUSTAINABILITY
Published 2019-09-01“…Despite the introduction of various methods aimed at increasing the security of information resources in the information and telecommunication systems, the dynamics of the increase and the effects of cybernetic threats, both in the world and in Ukraine, remain rather high and constitute a world-class problem. In connection with this, there is an urgent need to ensure the effective functioning of heterogeneous information and telecommunication networks (ITN) of the Ministry of Defense and Armed Forces of Ukraine in the conditions of cyber attacks. …”
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2343
Understanding strategies for overcoming peripherality: A Polish experience of transition
Published 2018-06-01“…This article addresses the problematic county of Wieruszow-a peripheral area of Poland, constituting a classic case of historical development away from urban agglomerations, additionally burdened by the stigma of a former near-border location, and later (including today) functioning at the fringe of an administrative district. …”
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2344
The IL-33/ST2 axis and tissue Treg maintain epithelial homeostasis and restrain cancer development in the skin
Published 2025-06-01“…Summary: Interleukin (IL)-33 is constitutively expressed in many epithelial tissues at steady state and signals through the receptor, ST2. …”
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2345
LINC00622 transcriptionally promotes RRAGD to repress mTORC1-modulated autophagic cell death by associating with BTF3 in cutaneous melanoma
Published 2025-07-01“…As the central hub of nutrient signaling and cell growth, mTOR constitutes mTORC1 to be the main gateway for modulating autophagy. …”
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2346
Chromosome-level genome assembly and annotation of Gypsophila vaccaria
Published 2025-05-01“…A total of 21,795 protein-coding genes were predicted, and repetitive elements were found to constitute 80.43% of the assembled genome. This chromosome-level genome assembly serves as an invaluable resource for future research, including functional genomics and molecular breeding of G. vaccaria.…”
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2347
Bioactive Peptides Derived from Tuna: Screening, Extraction, Bioactivity, and Mechanism of Action
Published 2025-07-01“…Peptides play a crucial role in the development of pharmaceuticals and functional foods. Multiple studies have shown that natural bioactive peptides possess antioxidant, antihypertensive, anti-tumor, and anti-inflammatory activities. …”
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2348
Deciphering Membrane Proteins Through Deep Learning Models by Revealing Their Locale Within the Cell
Published 2024-11-01“…Membrane proteins constitute essential biomolecules attached to or integrated into cellular and organelle membranes, playing diverse roles in cellular processes. …”
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2349
Chromosome-level genome assembly and annotation of Chinese herring (Ilisha elongata)
Published 2025-04-01“…Repetitive sequences were annotated via ab initio and homology predictions, identifying 295.7 Mb of repetitive sequences, constituting 35.08% of the genome. A total of 26,381 protein-coding genes were predicted, with 24,596 functionally annotated.…”
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2350
Clinical and preclinical insights into a novel MDM2::PDGFRA fusion in recurrent glioblastoma
Published 2025-08-01“…In this study, we identify and functionally characterize a novel amplified fusion, MDM2 (exon 1)::PDGFRA (exon 8), mediating resistance to cetuximab in an EGFR-amplified glioblastoma. …”
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2351
Carbene-supported triphosphorus anion
Published 2025-03-01“…Abstract The stabilization of reactive anionic main group species utilizing carbenes constitutes a burgeoning and scarcely explored field. …”
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2352
Telomere-to-telomere genome assembly of Phoxinus lagowskii
Published 2025-06-01“…The transposable elements constituted 512.40 Mb (49.22%) of the assembled P. lagowskii genome, with DNA transposons 25.02% being the predominant repeat type. …”
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2353
Expedient access to bora-butenolide bioisosteres by counteranion-mediated trans-hydroboration of alkynes
Published 2025-05-01“…The practical method is distinguished by excellent regioselectivity, a broad substrate scope, and high compatibility with a variety of functional groups. The exploration of trans-selective patterns affords not only a stereo-complementary approach to traditional organic synthesis, but also mandates a new perspective on the noncanonical trans-hydroboration mechanism. …”
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2354
Tailoring Coherent Microwave Emission from a Solid‐State Hybrid System for Room‐Temperature Microwave Quantum Electronics
Published 2024-09-01“…The work not only pushes the boundaries of the operating frequency and functionality of the existing pentacene masers but also demonstrates a universal route for controlling the masing process at room temperature, highlighting opportunities for optimizing emerging solid‐state masers for quantum information processing and communication.…”
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2355
Fermented Cashew Apple Beverages: Current State of Knowledge and Prospects
Published 2025-04-01“…The cashew apple constitutes approximately 90% of the total fruit mass produced by the cashew tree, with the remaining 10% being the cashew nut. …”
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2356
A comprehensive review on elucidating the host disease resistance mechanism from the perspective of the interaction between cotton and Verticillium dahliae
Published 2025-02-01“…In this review, we comprehensively discuss genetic inheritance associated with Verticillium wilt resistance in cotton, the advancements in molecular markers for disease resistance, the functional investigation of resistance genes in cotton, the analysis of pathogenicity genes in V. dahliae, as well as the intricate interplay between cotton and this fungus. …”
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2357
Fatty acid desaturase genetic variations in heart failure and cardiovascular disease
Published 2025-05-01“…Omega (ω)-3 polyunsaturated fatty acids (PUFAs) have gained prominence for their putative cardioprotective functions. However, the data supporting their beneficial effects has been inconsistent. …”
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2358
The Role of Post-Translational Modifications in Necroptosis
Published 2025-04-01“…Post-translational modifications (PTMs)—chemical alterations occurring after protein synthesis that critically regulate protein functionality—constitute essential regulatory components within these complex signaling cascades. …”
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2359
Communities of Dung Beetles (Coleoptera: Scarabaeoidea) in the Steppe of Mongolia
Published 2021-02-01“…We found 15 species of dung beetles belonging to three families and representing two functional guilds, namely paracoprids and endocoprids. …”
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2360
Ethno-religious Beliefs and Patients’ Healthcare-seeking Behavior in Nigeria
Published 2025-05-01“…This gap invariably constitutes not only a high mortality rate but large-scale human insecurity in terms of loss of lives in the country. …”
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