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  1. 2261

    Black carp RNF115 restricts IRF3/7-mediated antiviral signaling in innate immunity by Yixuan He, Qun Wang, Lili Xiao, Hui Wu, Jun Xiao, Jun Zou, Hao Feng

    Published 2025-01-01
    “…In this paper, we cloned the RNF115 homologue from black carp (Mylopharyngodon piceus) and characterized it. The open reading frame of black carp RNF115 contains 933 nucleotides and encodes 310 amino acids. …”
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  2. 2262
  3. 2263

    Users’ Perspectives of Direct-to-Consumer Telemedicine Services: Survey Study by Kate Churruca, Darran Foo, Andrew Turner, Emily Crameri, Maree Saba, Samantha Spanos, Matthew Vickers, Jeffrey Braithwaite, Louise A Ellis

    Published 2025-02-01
    “…The most frequently cited reasons for using DTC telemedicine were related to convenience (97/121, 80.2%) and flexibility (71/121, 58.7%), while approximately a third of the sample selected that it was difficult to see traditional health care provider in their preferred time frame (44/121, 36.4%) and that the use of DTC telemedicine allowed them to gain access to services otherwise unavailable through traditional health care (39/121, 32.2%). …”
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  4. 2264

    Eu:CROPIS AIV Program: Challenges and Solutions for a Spin-Stabilized Satellite Containing Biology by Toni Delovski, Catherin Düvel, Fabian Greif, Ansgar Heidecker, Sebastian Kottmeier, Olaf Mierheim, Falk Nohka, Fabian Orlowski-Feldhusen

    Published 2019-01-01
    “…In consequence, the clean room facilities of the DLR Institute of Space Systems had to be certified to BSL-1 and new test infrastructure had to be procured in a short time frame to cover for acceptance testing. The design of the satellite and nature of the attitude control subsystem required limits on the magnetic momentum of the system and every unit it contains. …”
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  5. 2265

    A novel protein encoded by porcine circANKRD17 activates the PPAR pathway to regulate intramuscular fat metabolism by Xiao He, Fang Xie, Ying Nie, Xuefeng Wang, Junyi Luo, Ting Chen, Qianyun Xi, Yongliang Zhang, Jiajie Sun

    Published 2025-02-01
    “…In addition, we discovered that circANKRD17 has an open reading frame and can be translated into a novel 571-amino-acid protein that promotes lipid metabolism. …”
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  6. 2266

    Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence by Xiaoyin Wu, Xiaoyin Wu, Buyu Guo, Buyu Guo, Xingyu Chang, Xingyu Chang, Yuxuan Yang, Yuxuan Yang, Qianqian Liu, Qianqian Liu, Jiahui Liu, Jiahui Liu, Yichen Yang, Yichen Yang, Kang Zhang, Yumei Ma, Songbo Fu, Songbo Fu, Songbo Fu

    Published 2025-01-01
    “…In vitro, ELF3, LCN2 and CD163 were induced in high glucose-induced HK-2 cell lines.ConclusionAn integrative machine learning frame established a novel diagnostic signature using glycolysis-related genes. …”
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  7. 2267

    Adaptación y dimensionalidad de la escala DOCS en el contexto organizacional costarricense: aplicación de la entrevista cognitiva y el análisis factorial confirmatorio/ Adaptation... by Tómas Vargas-Halabí, Ronald Mora-Esquivel

    Published 2017-12-01
    “…It was then applied in two samples, with similar characteristics, but belonging two different populations: a) 314 students drawn from 445 active students enrolled in Master’s Programs (MBA and Project Management) at the Costa Rican Institute of Technology, whose prerequisite for admission stipulates experience in professional positions, preferably supervisory and managerial, and; b) 368 managers drawn from a sampling frame of 1743 companies from various business associations. …”
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  8. 2268

    Global vaccine research and application hotspots and trends: a systematic bibliometric analysis based on SCIE highly cited papers by Liming Liang, Xinyu Wang, Yue Zhu, Xu Xia, Runfeng Shi, Huilin Cao, Meixin He, Yuyu Wang, Caizhen You

    Published 2025-01-01
    “…In view of these facts, the current situation, status, problems and development trends of vaccine research and application were explored through bibliometric analysis of highly cited papers in the vaccine field within the time frame of 2014–2024, and the countries, institutions, authors, funding agencies and other relevant information that contributed most to vaccine research and application were summarised.Design Bibliometric analysis through data analysis and visual mapping.Data sources Scientific articles.Data extraction and synthesis ‘Vaccine’ and ‘vaccines’ were used in the WoS database to retrieve the publications and to adequately collect the data; Microsoft Excel was used for data analysis; and VOSviewer was used for visual description of data. …”
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  9. 2269
  10. 2270

    The Metempiricism of Margins: Professor Anthony Aṣiwaju and the Circumference of Knowledge by Toyin Falola

    Published 2021-12-01
    “…I think Professor Aṣiwaju’s life breaks the rules, creating a frame much larger than his beginnings. Contrary to the man-confining adage of “cut your coat according to your cloth/size,” the autobiography of Professor Aṣiwaju has exemplified that the Supreme God cuts and designs coat without the delimitations or regard of one’s size or cloth. …”
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  11. 2271
  12. 2272

    Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples by Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Vladimir Lyadov, Vladimir Lyadov, Vladimir Lyadov, Maria Suntsova, Marat Garipov, Anna Semenova, Natalia Popova, Egor Guguchkin, Rustam Heydarov, Marianna Zolotovskaia, Xiaowen Zhao, Qing Yan, Ye Wang, Evgeny Karpulevich, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin

    Published 2025-01-01
    “…Finally, in one patient, we detected a potentially clinically actionable in-frame fusion of LRRFIP2 and ALK genes not previously described in colorectal cancer with an intact tyrosine kinase domain that can be potentially targeted by ALK inhibitors.…”
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  13. 2273
  14. 2274

    Severe neonatal hypotonia due to SLC30A5 variant affecting function of ZnT5 zinc transporter by Vadim Dolgin, Pauline Chabosseau, Jacob Bistritzer, Iris Noyman, Orna Staretz‐Chacham, Ohad Wormser, Noam Hadar, Marina Eskin‐Schwartz, Bibi Kanengisser‐Pines, Ginat Narkis, Ramy Abramsky, Eilon Shany, Guy A. Rutter, Kyla Marks, Ohad S. Birk

    Published 2025-01-01
    “…Combining homozygosity mapping and exome sequencing studies of consanguineous Bedouin kindred, as well as transfection experiments and zinc monitoring in HEK293 cells, we demonstrate that a bi‐allelic in‐frame 3bp deletion variant in SLC30A5, deleting isoleucine within the highly conserved cation efflux domain of the encoded ZnT5, results in lower cytosolic zinc concentrations, causing a syndrome of severe non‐progressive neonatal axial and limb hypotonia with high‐arched palate and respiratory failure. …”
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  15. 2275
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  17. 2277

    Concomitant exposure to benzodiazepines during pembrolizumab-based therapy for advanced non-small-cell lung cancer: a propensity-score matched analysis of monitoring agency data by Fabrizio Nelli, Enzo Maria Ruggeri, Antonella Virtuoso, Diana Giannarelli, Armando Raso, Federica Natoni, Gloria Pessina, Daniele Remotti, Mario Giovanni Chilelli, Carlo Signorelli, Agnese Fabbri

    Published 2025-01-01
    “…Results: During the time frame from April 2018 to May 2023, we enrolled 258 patients, 156 (60.5%) and 102 (39.5%) of whom received pembrolizumab alone or the combination regimen, respectively. …”
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  18. 2278
  19. 2279

    N‐terminal pro brain natriuretic peptide reference values in community‐dwelling older adults by Ulrike Braisch, Wolfgang Koenig, Dietrich Rothenbacher, Michael Denkinger, Nele Friedrich, Stephan B. Felix, Till Ittermann, Marcus Dörr, Dhayana Dallmeier

    Published 2022-06-01
    “…Our results attempt to provide a frame for the further investigation of age‐specific NT‐proBNP cut‐offs in older adults. …”
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  20. 2280

    Determination of the physicochemical and microbiological quality of buffalo milk in the south of lake Maracaibo by Luis Álvarez, Alexis Zambrano, Datty Rosales-Zambrano

    Published 2023-11-01
    “…The microbiological quality indicators indicate that the processes for obtaining milk must be improved and framed in practice that guarantee the safety of raw milk. …”
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