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    The influence of monosodium glutamate on the development of oxidative-nitrosative stress in the large cerebral hemispheres of rats under the combination of a change in the “light-d... by O. A. Volkova, O. Ye. Akimov, V. O. Kostenko

    Published 2024-06-01
    “…In a 10 % homogenate of the large cerebral hemispheres, we determined the rate of superoxide anion radical (SAR) production, the content of products that react with thiobarbituric acid (TBA-reactants), their increase, activity of catalase, superoxide dismutase (SOD), ornithine decarboxylase (ODC), concentration of nitrites, peroxynitrites, total activity of NO-synthase (NOS), its constitutive (cNOS) and inducible (iNOS) isoforms. Results. In the group of SIR, AD and glutamate combination, compared to the control, the following was noted: an increase in the rate of basic production of SAR by 175.8 %, by the microsomal pathway by 20.0 %, by the mitochondrial pathway by 51.2 %, the concentration of TBA-reactants by 83.4 %, their increase – by 61.7 %, decrease in the activity of SOD by 57.1 %, catalase – by 38.1 %; an increase in peroxynitrite content by 116.7 %, ODC activity by 161.5 %, total NOS activity by 25.6 % and iNOS by 27.4 %, a decrease in cNOS activity by 15.0 % and nitrite concentration by 35.0 % in brain tissues. …”
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    Surface Roughness and Color Stability of Conventional and Bulk-Fill Resin Composite with S-PRG Fillers After Coffee Exposure: An in-vitro Study by Janisch FADS, Falcon Aguilar M, Aguiar FHB, França FMG, Basting RT, Vieira-Junior WF

    Published 2025-01-01
    “…For ΔE00, a significant difference was noted between Beautifil Bulk Restorative and Beautifil II (p < 0.05).Conclusion: Resin composites with S-PRG fillers exhibited similar pigmentation dynamics to conventional composite but showed greater surface roughness after exposure to coffee. …”
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  14. 794

    Optimum technique of carotid artery reconstruction in her atherosclerotic lesion by V. V. Akhmetov, V. I. Dunaeva, F. A. Vryganov, S. V. Ordynets, I. P. Dudano

    Published 2020-12-01
    “…When assessing the geometrical changes in the group with the patching, it was noted that the worst results were obtained using the technique with a U-shaped fixation suture on the distal part of the patch and the use of a wide patch. …”
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  15. 795

    Burden of type 2 diabetes due to high body mass index in different SDI regions and projections of future trends: insights from the Global Burden of Disease 2021 study by Yun-fa Ding, An-xia Deng, Teng-fei Qi, Hao Yu, Liang-ping Wu, Hong-bing Zhang

    Published 2025-01-01
    “…In addition, the study noted that individuals in the 65- to 75-year-old age group accounted for a higher proportion of T2DM-related deaths and DALYs, with females affected at a greater rate than males. …”
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  16. 796

    Safety and feasibility of En‐bloc holmium laser enucleation for very large prostates (> 200 cc) with trainee involvement by Feres C. Maluf, Ansh Bhatia, Archan Khandekar, Diana M. Lopategui, Joao G. Porto, Ryan R. Chen, Jean C. Daher, Mohamadhusni Zarli, Robert Marcovich, Hemendra N. Shah

    Published 2025-01-01
    “…Median postoperative PSA was 0.4 [0.21–0.78] ng/ml. At 1‐year follow‐up, mean IPSS was 1 ± 2.4, Qmax was 27.03 ± 11.57 ml/s and PVR was 21.6 ± 28.6 ml. …”
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    Cresp®: transforming the landscape of chemotherapy-induced anemia - a comprehensive retrospective real-world analysis in 523 Indian patients by MV Chandrakanth, Vivek Agarwala, Pranav Sopory, Himadri Nayak, Purvish M. Parikh, Minakshi Roy, Rajib De, Pradeep Narayan, Anjuli Tuladhar Barai, Kaustav Mandal, Moinak Basu, Subhabrata Kumar, Rajdeep Singh Uppal, Syed Mujtaba Hussain Naqvi, Rohit Desai

    Published 2025-01-01
    “…Significant improvements were noted from baseline in fatigue, and dyspnea. Adverse drug reactions included hypertension (5.4%), deep vein thrombosis (2.9%), and arrhythmias (0.8%).DiscussionDA demonstrates impressive efficacy and safety in managing CIA, leading to substantial improvements in mean hemoglobin levels in palliative setting. …”
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    Analyzing the discourse of tourism development with a justice-oriented and moderate approach by Mostafa Ghodrati, Mehraban Hadipeykani, Reza Ebrahimzadeh

    Published 2024-09-01
    “…Looking at the data in the table, it can be said that almost the level of expertise of the managers of all four periods is in the average level and it has affected the efficiency and effectiveness.…”
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