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Should the Food and Drug Administration Limit Placebo-Controlled Trials?
Published 2022-07-01“…The Common Rule requires IRBs for human research and reflects principles noted in the Belmont Report. The Belmont Report covers three applications of its principles: Informed consent, selection of research subjects, and risk-benefit assessments.[10] In 1979, Beauchamp and Childress established the four principles approach to bioethics including autonomy, beneficence, nonmaleficence, and justice. …”
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Ablation Depth-Dependent Survival Analysis of Phototherapeutic Keratectomy for Recurrent Corneal Erosion Syndrome
Published 2024-11-01“…Methods Retrospective case notes review with prospective patient-reported outcome measures for all patients who had undergone PTK for RCES at a single tertiary referral unit. …”
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The Effects of Microseconds Electroporation on Pore Size, Viability and Mitochondrial Membrane Potential of Cervical Cancer Cells
Published 2025-01-01“…A slight decrease in ΔΨm was observed between the control and the 0.8 and 1.6 kV/cm EP groups, but ΔΨm was higher in the 2.4 and 3.2 kV/cm EP groups compared to the control group. …”
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Association of the triglyceride glucose index with obesity indicators and hypertension in American adults based on NHANES 2013 to 2018
Published 2025-01-01“…Results showed strong correlations between TyG, TyG-BMI, TyG-WHtR, TyG-WC and hypertension, with odds ratios (ORs) of hypertension rising across TyG quartiles (Q1–Q4). Cardiovascular mortality analysis revealed that TyG (HR = 1.89, 95% CI (1.03,3.51), P < 0.05) and the Q2 group (HR = 4.93, 95% CI (1.29,18.80), P < 0.05) were significantly associated with increased risk. …”
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Bond Strength of Porcelain Fused to Casting and Selective Laser Base Metal Alloy with a Bonding Agent
Published 2022-09-01Get full text
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Facilitation of students’ disembedding in an online visual arts and mathematics education program
Published 2025-02-01Get full text
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The Content-Validated Geometry Lessons in Islam Observed Brain-based Learning
Published 2023-11-01“…Designed in a qualitative grounded theory approach, an interview script was used for individual and focus group interviews. Ten content validated -lessons in geometry were designed to capture the Islamized learning phenomenon wherein field notes of observations and video footages were qualitatively analyzed using the lens of systematic approach coined as constant comparative method of analysis. …”
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mHealth App to Promote Healthy Lifestyles for Diverse Families Living in Rural Areas: Usability Study
Published 2025-02-01“…MethodsDuring a 3-phased approach, usability testing was conducted with a diverse group of parents. In total, 7 mothers of children with obesity from rural communities (average age 39, SD 4.9 years; 4 Spanish-speaking and 3 English-speaking) provided feedback on a prototype of the dashboard. …”
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A randomized double-blind active-controlled clinical trial on the efficacy of topical basil (Ocimum basilicum) oil in knee osteoarthritis
Published 2024-05-01“…However, significant improvements were noted within each group for most variables.ConclusionTopical application of the traditional formulation of basil oil appears to improve clinical symptoms and certain functional indicators of knee osteoarthritis to a similar extent as diclofenac gel. …”
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Effect of epileptiform discharges and hippocampal volume on cognitive dysfunction following clipping of ruptured aneurysms in the anterior circulation
Published 2025-01-01“…A significant difference was noted in elevated SI on the approach side of the MCA (p < .001), ICA (p < .001), and ACA (p < .001) in the transsylvian approach group. …”
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Experimental evidence-based construction of electroacupuncture for ischemic stroke: a meta-analysis and systematic review
Published 2025-02-01“…Data on cerebral infarction volume, neurological deficit scores, cellular apoptosis, and molecular pathways were extracted and analyzed.ResultsEleven eligible studies involving 302 animals (151 in EA treatment groups and 151 in control groups) were included. Meta-analysis revealed that EA significantly reduced cerebral infarction volumes [MD = −15.78, 95%CI (−21.40, −10.16), p < 0.05] and TUNEL-positive cells [MD = −26.46, 95%CI (−40.40, −12.51), p < 0.05], indicating reduced apoptosis. …”
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