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    Should the Food and Drug Administration Limit Placebo-Controlled Trials? by Max Goodman, Connor Pedersen

    Published 2022-07-01
    “…The Common Rule requires IRBs for human research and reflects principles noted in the Belmont Report. The Belmont Report covers three applications of its principles:  Informed consent, selection of research subjects, and risk-benefit assessments.[10] In 1979, Beauchamp and Childress established the four principles approach to bioethics including autonomy, beneficence, nonmaleficence, and justice. …”
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  6. 686

    Ablation Depth-Dependent Survival Analysis of Phototherapeutic Keratectomy for Recurrent Corneal Erosion Syndrome by Kunal A. Gadhvi, Georgios Vakros, Alfredo Borgia, Kirithika Muthusamy, Laura de Benito-Llopis, Alexander C. Day, Daniel M. Gore

    Published 2024-11-01
    “…Methods Retrospective case notes review with prospective patient-reported outcome measures for all patients who had undergone PTK for RCES at a single tertiary referral unit. …”
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  7. 687

    The Effects of Microseconds Electroporation on Pore Size, Viability and Mitochondrial Membrane Potential of Cervical Cancer Cells by Güney GÜRSOY, Meriç Arda ESMEKAYA, Zehra ÇİÇEK

    Published 2025-01-01
    “…A slight decrease in ΔΨm was observed between the control and the 0.8 and 1.6 kV/cm EP groups, but ΔΨm was higher in the 2.4 and 3.2 kV/cm EP groups compared to the control group. …”
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    Association of the triglyceride glucose index with obesity indicators and hypertension in American adults based on NHANES 2013 to 2018 by Pingping Huang, Hongwei Zhang, Gaocan Ren, Yifei Wang, Shuangqing Fu, Yicheng Liu, Zhibo Zhang, Lijun Guo, Xiaochang Ma

    Published 2025-01-01
    “…Results showed strong correlations between TyG, TyG-BMI, TyG-WHtR, TyG-WC and hypertension, with odds ratios (ORs) of hypertension rising across TyG quartiles (Q1–Q4). Cardiovascular mortality analysis revealed that TyG (HR = 1.89, 95% CI (1.03,3.51), P < 0.05) and the Q2 group (HR = 4.93, 95% CI (1.29,18.80), P < 0.05) were significantly associated with increased risk. …”
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    The Content-Validated Geometry Lessons in Islam Observed Brain-based Learning by Sherma O. Sappari, Florante P. Ibarra, Amirul Mukminin, Kasinyo Harto, Lenny Marzulina, Herri Mulyono, Asmendri Asmendri

    Published 2023-11-01
    “…Designed in a qualitative grounded theory approach, an interview script was used for individual and focus group interviews.  Ten content validated -lessons in geometry were designed to capture the Islamized learning phenomenon wherein field notes of observations and video footages were qualitatively analyzed using the lens of systematic approach coined as constant comparative method of analysis. …”
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  17. 697

    mHealth App to Promote Healthy Lifestyles for Diverse Families Living in Rural Areas: Usability Study by Alejandra Perez Ramirez, Adrian Ortega, Natalie Stephenson, Angel Muñoz Osorio, Anne Kazak, Thao-Ly Phan

    Published 2025-02-01
    “…MethodsDuring a 3-phased approach, usability testing was conducted with a diverse group of parents. In total, 7 mothers of children with obesity from rural communities (average age 39, SD 4.9 years; 4 Spanish-speaking and 3 English-speaking) provided feedback on a prototype of the dashboard. …”
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  18. 698

    A randomized double-blind active-controlled clinical trial on the efficacy of topical basil (Ocimum basilicum) oil in knee osteoarthritis by Alireza Askari, Fatemeh Sadat Hasheminasab, Fatemeh Sadat Hasheminasab, Omid Sadeghpour, Mohammad Mehdi Naghizadehd, Seyed Ali Ravansalar, Aida Iraji, Mohammad Hashem Hashempur

    Published 2024-05-01
    “…However, significant improvements were noted within each group for most variables.ConclusionTopical application of the traditional formulation of basil oil appears to improve clinical symptoms and certain functional indicators of knee osteoarthritis to a similar extent as diclofenac gel. …”
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    Effect of epileptiform discharges and hippocampal volume on cognitive dysfunction following clipping of ruptured aneurysms in the anterior circulation by Kunitoshi Otsuka, Shigeki Sunaga, Hiroyuki Jimbo, Yoshinori Suzuki, Michihiro Kohno

    Published 2025-01-01
    “…A significant difference was noted in elevated SI on the approach side of the MCA (p &lt; .001), ICA (p &lt; .001), and ACA (p &lt; .001) in the transsylvian approach group. …”
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    Experimental evidence-based construction of electroacupuncture for ischemic stroke: a meta-analysis and systematic review by Yaoguang Guo, Sihan Hu, Sihan Hu, Shiman Luo, Lang Tu, Yao Tang, Fang Zeng, Fang Zeng, Fang Zeng

    Published 2025-02-01
    “…Data on cerebral infarction volume, neurological deficit scores, cellular apoptosis, and molecular pathways were extracted and analyzed.ResultsEleven eligible studies involving 302 animals (151 in EA treatment groups and 151 in control groups) were included. Meta-analysis revealed that EA significantly reduced cerebral infarction volumes [MD = −15.78, 95%CI (−21.40, −10.16), p &lt; 0.05] and TUNEL-positive cells [MD = −26.46, 95%CI (−40.40, −12.51), p &lt; 0.05], indicating reduced apoptosis. …”
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