Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti... by Arndt Borkhardt, Nan Qin, Stephen T Keir, Darell D Bigner, Allison Cole, Matthias Wölfl, Viktoria Marquardt, Johanna Theruvath, David Pauck, Daniel Picard, Lena Blümel, Mara Maue, Jasmin Bartl, Ulvi Ahmadov, Maike Langini, Frauke-Dorothee Meyer, Joselyn Cruz-Cruz, Claus M Graef, Till Milde, Olaf Witt, Anat Erdreich-Epstein, Gabriel Leprivier, Ulf Kahlert, Anja Stefanski, Kai Stühler, Julia Hauer, Thomas Beez, Christiane B Knobbe-Thomsen, Ute Fischer, Jörg Felsberg, Finn K Hansen, Rajeev Vibhakar, Sujatha Venkatraman, Samuel H Cheshier, Guido Reifenberger, Thomas Kurz, Marc Remke, Siddhartha Mitra

“…Background While major advances have been made in improving the quality of life and survival of children with most forms of medulloblastoma (MB), those with MYC-driven tumors (Grp3-MB) still suffer significant morbidity and mortality. …”
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Structure variety and its potential effects on biological activity of tea polysaccharides by Ting Hu, Peng Wu, Jianfeng Zhan, Weixin Wang, Junfeng Shen, Meiyan Wang, Chi-Tang Ho, Shiming Li

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Analytical Solution for the Gross-Pitaevskii Equation in Phase Space and Wigner Function by A. X. Martins, R. A. S. Paiva, G. Petronilo, R. R. Luz, R. G. G. Amorim, S. C. Ulhoa, T. M. R. Filho

“…As a consequence a nonlinear Schrödinger equation is derived in phase space. The formalism is based on the noncommutative structure of the star product, and using the group theory approach as a guide a physically consistent theory is constructed in phase space. …”
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Understanding Hip Contact Stress Based on Types of Physical Activity: A Systematic Review by Arief Indra Perdana Prasetya, Muhammad Imam Ammarullah, Tri Indah Winarni, Adriyan Pramono, Jamari Jamari, Tunku Kamarul, Ardiyansyah Syahrom

“…Full articles that matched our inclusion criteria were selected using PubMed, Web of Science, and Scopus search engines and keywords such as “hip contact stress,” “hip contact force,” and/or “hip contact pressure.” Category of factors, experimental design, results of the study, and evidence from each article were analyzed. …”
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Median nerve entrapment neuropathy: a review on the pronator syndrome by Saud Binsaleem, MD

“…Pronator syndrome is a compression neuropathy of the median nerve within the anatomical structures of the elbow and forearm. It presents with neuropathic pain, numbness, and weakness of the forearm and hand, which are often exacerbated by repetitive pronation-supination movements. …”
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Analysis of Meshing Characteristic and Return Clearance of Precision Cycloid Transmission for Robot by Zhang Liyong, Zhou Hongkai, Wang Changlu, Qiao Xuetao

“…The influence of different tooth modification methods on the number of meshing teeth,force and distortion of each mesh point and the return clearance of cycloid transmission is calculated through iterative method. …”
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Systemic Inflammation and Acute-on-Chronic Liver Failure: Too Much, Not Enough by Wim Laleman, Joan Claria, Schalk Van der Merwe, Richard Moreau, Jonel Trebicka

“…ACLF is a specific, but complex and multifactorial form of acute decompensation of cirrhosis and is characterized by an extraordinary dynamic natural course, rapidly evolving organ failure, and high short-term mortality. …”
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Functional transposition of TILL and UNTIL from a diachronic perspective by Kovbasko Yurii

“…It is hypothesized that despite being synonyms and representatives of the same grammatical categories of prepositions and conjunctions in modern English, the lexical units TILL and UNTIL were initially formed as prepositions and later, following their own transpositional patterns, they were transposed into conjunctions.…”
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Editorial Vol6 no2 by Irene Stevens

“…Changing Lives (Scottish Executive, 2006), otherwise known as the Report of the 21st Century Social Work Review will be the key policy document for social service development and reform in the foreseeable future. The bulk of the report discusses the role of the social worker, and residential child care is not discussed specifically. …”

Multisite Infection with Mycobacterium abscessus after Replacement of Breast Implants and Gluteal Lipofilling by Eva Rüegg, Alexandre Cheretakis, Ali Modarressi, Stephan Harbarth, Brigitte Pittet-Cuénod

“…As NTM grow in biofilms, implantations of foreign bodies are at risk. Due to late manifestation, infections occur when patients are back home, where they must be managed properly. …”
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miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1 by Yang Ke, Weiyong Zhao, Jie Xiong, Rubo Cao

“…Furthermore, we demonstrated that miR-149 directly targeted Forkhead box M1 (FOXM1), and FOXM1 was involved in the EMT induced by TGF-β1 in A549 cells. …”
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Dynamic Characteristic Analysis and Experimental Investigation on Gearbox Housing of Heavy Scraper Conveyor by Cao Baolin, Zhang Yunbo, Lü Kaibo, Ji Chaoyue, Li Zhizhong, Lian Zisheng

“…Under the rated load condition,through dynamics analysis simulation and experiments,the supporting dynamic reaction force and boundary condition of gearbox housing are determined,the transient stress and vibration response characteristics of the CST gearbox housing are analyzed,and the weak location of natural characteristic and rigidity of gearbox is acquired. …”
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Zika, a Mosquito-Transmitted Virus by L. Phil Lounibos, Barry W. Alto, Nathan D. Burkett-Cadena, Cynthia C. Lord, Chelsea T. Smartt, C. Roxanne Rutledge Connelly, Jorge R. Rey

“…In its native range in West Africa and Uganda, the Zika virus stays in the forest for the most part, and human infections are considered incidental and medically inconsequential. …”
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Power and authority in Matthew's gospel by F. P. Viljoen

“…Herod, Antipas and Pilate specifically impersonate this foreign domination. Apparently these figures have unlimited power which leaves Jesus and his followers as exposed victims. …”
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Le retour des communs by Benjamin Coriat

“…In addition to recalling the discussion that spread around the famous article of Hardin on the “Tragedy of the commons”, the emphasis is put on an essential but little-known episode of the history of the commons: the conference hold in Annapolis in 1983 at the inititiave of the NRC (National Research Council) to review the forms of ownership and rural exploitation in tropical countries that were at that time experiencing severe degradation and a fall in productivity. …”
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2013 Okul Öncesi Eğitim Programının Değerlendirilmesi by Semra Tican Başaran, Özgür Ulubey

“…Araştırmanın nicel verileri, araştırmacılar tarafından geliştirilen okul öncesi eğitim programını değerlendirme anketi, nitel verileri ise yarı yapılandırılmış görüşme formu ile toplanmıştır. Araştırma kapsamında toplanan nicel veriler betimsel analizler, nitel verileri ise tümevarımsal içerik analizi ile çözümlenmiştir. …”
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Labor Industry Allocation, Industrial Structure Optimization, and Economic Growth by Liyuan Shi

“…The allocation of production factors among industries affects the evolution of industrial structure and then acts on economic growth. Labor force is one of the most important factors of production. …”
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Growth and Comprehensive Quality Index of Tomato under Rain Shelters in Response to Different Irrigation and Drainage Treatments by Guang-cheng Shao, Ming-hui Wang, Na Liu, Min Yuan, Prem Kumar, Dong-Li She

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The Experience of University Department in Organizing Research Circles at Schools as a Direction of University Career Guidance Work by E. A. Kogan, D. I. Ponomareva

“…The authors present an experience of organizing and conducting research circles in sociology and social psychology for students of grades 8-11.The activity of the sociological research circle “First steps in science” was aimed at forming students’ ideas about research, its methods and stages; developing skills of independent work with the received social information; obtaining skills for developing, conducting and presenting research results. …”
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Disease burden of biliary tract cancer in 204 countries and territories, 1990–2021: A comprehensive demographic analysis of the Global Burden of Disease Study 2021 by Xuheng Sun, Jiangmei Liu, Wei Zhang, Yijun Wang, Yan Jiang, Lijun Wang, Yixin Zou, Yuxuan Xiao, Yongbing Xiang, Maolan Li, Maigeng Zhou, Yingbin Liu, Sihan Zhou, Xiuyuan Hao

“…This study provided a comprehensive comparison of differences in the burden of disease across populations and over time, and further presented evidence concerning the formulation of prevention and control policies and etiologic studies for BTCs and proposed logical hypotheses to investigate.…”
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