Drug Clues for the Treatment of Fungal Catheter-Related Bloodstream Infection With Antifungal Lock Therapy by Li X, Yu B, Li H, Liu Z, Fu X, Jiao P, Wang L

“…Shandong First Medical University @ Shandong Academy of Medical Sciences, Jinan, 250117, People’s Republic of ChinaCorrespondence: Ping Jiao; Lei Wang, Email jiaopingonlyone@163.com; wanglei1118@sdfmu.edu.cnBackground: Biofilm formation often represents significant challenges in managing of bloodstream infections associated with catheter use.Objective: Antimicrobial lock therapy serves as an adjunctive treatment for catheter-related infections, effectively eradicating or inhibiting biofilm growth.Methods: This review synthesizes the current knowledge on antifungal lock therapy (ALT) targeting clinically common fungi, primarily Candida species, based on both in vitro and in vivo studies (animals and patients) from the past decade.Results: Amphotericin B (AmB) and echinocandins are identified as the most promising antifungal agents for ALT. …”
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De sur a sur. El intercambio técnico agrario entre Brasil y los países del Río de la Plata (1930-1955) by Carolina da Cunha Rocha

“…El artículo analiza el proceso de consolidación en Brasil de una administración agraria que requirió la formación científica y profesional de cuadros técnicos en cuestiones rurales entre 1930-1955, y rastreó los objetivos del gobierno brasileño en incrementar la cooperación tecnocientífica en materia agraria en el contexto sur-sur en esos años. …”
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« Retail the coda » : le retour au sonnet dans l’œuvre récente de Geoffrey Hill by Carole Birkan-Berz

“…In more recent volumes, however, the form seemed to have disappeared, only to survive in a palimpsestic way. …”
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Enhancing electric vehicle battery lifespan: integrating active balancing and machine learning for precise RUL estimation by Yara A. Sultan, Abdelfattah A. Eladl, Mohamed A. Hassan, Samah A. Gamel

“…Among these, k-nearest Neighbors and Random Forest models deliver the highest accuracy, achieving R2 values of 0.996 and above with low MAE, demonstrating strong predictive capability. …”
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Nodular Fasciitis Complicating a Staged Surgical Excision of Dermatofibrosarcoma Protuberans by C. Helen Malone, Brandon Goodwin, Richard F. Wagner, Vicente Resto, Brent Kelly

“…Dermatofibrosarcoma protuberans (DFSP) is an unusual spindle cell tumor with a high rate of local recurrence with traditional excision. Fortunately, Mohs micrographic surgery yields excellent cure rates for this neoplasm due to contiguous tumor spread and meticulous tumor mapping and margin analysis. …”
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ACTUAL PROBLEMS OF PERSONNEL POLICY AT THE ENTERPRISES OF PASSENGER MOTOR TRANSPORT by Y. Proshina

“…In the article the urgency of formation and implementation of personnel policies at the sector enterprises. …”
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Considerações sobre terceirização e precarização do trabalho no contexto brasileiro: uma revisão by Raquel Libório Feitosa, Adauto de Vasconcelos Montenegro

“…A  discussão  dos resultados  e  as  considerações  finais  deste  artigo  retomam  os  principais  achados  bibliográficos,  com  intuito  principal  de  suscitar formas de enfrentamento.…”
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A Brief Study to Clarify Some Aspects Related to Vibrational Density of States for the Far Infrared Range in Amorphous Semiconductors by M. A. Grado-Caffaro, M. Grado-Caffaro

“…On the basis of this formulation, optical absorption corresponding to structural disorder is evaluated and discussed at the far-infrared range for a-Ge and a-Si.…”
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Nε-Carboxymethyl-Lysine Negatively Regulates Foam Cell Migration via the Vav1/Rac1 Pathway by Zhengyang Bao, Lili Zhang, Lihua Li, Jinchuan Yan, Qiwen Pang, Zhen Sun, Yue Geng, Lele Jing, Chen Shao, Zhongqun Wang

“…Cytoskeletal staining showed that advanced glycation end products inhibited the formation of lamellipodia in foam cells, and inhibition of the Vav1/Rac1 pathway restored the formation of lamellipodia. …”
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Enhancing Paediatric and Strabismus Ophthalmology Departments in Spain Through the Inclusion of Orthoptists: Insights from a Nationwide Survey by Ana María Cruz Lasso

“…Open-ended questions captured themes, and comments. Results: Forty-two paediatric and strabismologists in Spain participated, mostly hospital-employed with advanced degrees, 90% supported integrating orthoptists into their teams, with 83% interested in having them in their workplace. …”
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Siltuximab-Related Favorable Clinical Outcome for a Patient Suffering from Idiopathic Multicentric Castleman Disease by Stamatios Chrysochoou, Andreas Kreft, Eberhard Schneider

“…RationalCastleman disease is a rare lymphoproliferative disorder that can be subdivided into unicentric and multicentric forms, the latter of which causes a spectrum of serious medical conditions. …”
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Tokay gecko tail regeneration involves temporally collinear expression of HOXC genes and early expression of satellite cell markers by Luthfi Nurhidayat, Vladimir Benes, Sira Blom, Inês Gomes, Nisrina Firdausi, Merijn A. G. de Bakker, Herman P. Spaink, Michael K. Richardson

“…In axolotls and zebrafish, regeneration involves stem cells produced by de-differentiation. These cells form a growth zone which expresses developmental patterning genes at its apex. …”
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Local wisdom-based instant cream soup as functional emergency food during health crises and disasters by Estuti Wiwit, Wayansari Lastmi, Rahman Nur, Nurul Alfiyah Isnar, Samuel Samuel, Kusmiyati Kusmiyati, Pertiwi Sinar, Rohmatin Etin, Widia Lestari Meti, Enis Rosulina Novi, Asti Rahmawati Vera

“…Background: The development of functional food with local ingredients of black soybeans and brown rice in the form of cream soup as emergency food is important. …”
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Experimental Investigation on Organic Matter Orientation Characteristics of Terrestrial and Marine Shale in China by Dunqing Liu, Hongkui Ge, Yinhao Shen, Kui Zhang

“…OM grains in samples from terrestrial C-7(Chang-7 Formation) exhibit the strongest directionality in their arrangement, and OM grains in samples from marine LMX (Longmaxi Formation) shale in the Fuling area also exhibit strong directional alignment. …”
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An elementary approach to modeling drug resistance in cancer by Cristian Tomasetti, Doron Levy

“…In contrast,our approach is based on an elementary, compartmental system of ordinarydifferential equations.We use our very simple approach to derive resultson drug resistance that are comparable to those that were previously obtained using much more complex mathematical techniques.The simplicity of our model allows us to obtain analytic results forresistance to any number of drugs.In particular, we show that the amountof resistance generated before the start of the treatment, and present at some given time afterward, always depends onthe turnover rate, no matter how many drugs are simultaneously used inthe treatment.…”
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Feature enhancement and bilinear feature vector fusion for text detection of mobile industrial containers by Haiyang HU, Zepin LI, Zhongjin LI

“…In the real factory environment, due to factors such as dim light, irregular text, and limited equipment, text detection becomes a challenging task.Aiming at this problem, a feature vector fusion module based on bilinear operation was designed and combined with feature enhancement and semi-convolution to form a lightweight text detection network RGFFD (ResNet18 + Ghost Module + FPEM(feature pyramid enhancement module)) + FFM(feature fusion module) + DB (differentiable binarization)).Among them, the Ghost module was embedded with a feature enhancement module to improve the feature extraction capability, the bilinear feature vector fusion module fused multi-scale information, and an adaptive threshold segmentation algorithm was added to improve the segmentation capability of the DB module.In the real industrial environment, the RGFFD detection speed reached 6.5 f/s, when using the embedded device UP2 board for text detection of container numbers.At the same time, the detection speed on the public datasets ICDAR2015 and Total-text reached 39.6 f/s and 49.6 f/s, respectively.The accuracy rate on the custom dataset reached 88.9%, and the detection speed was 30.7 f/s.…”
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Research on Tooth Surface Design of Curved Tooth Face Gear based on Cylindrical Gear Addendum Modified by Yong Chen, Zhanrong Feng, Yulong Zhao, Ning Huang, Lingfeng Gao, Guangjin Xiong

“…Face gear is a new gear transmission form in which involute cylindrical gear and approximate bevel gear mesh with each other. …”
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Hegemonia e distinção em manifestações de humoristas brasileiros sobre liberdade de expressão by Nara Lya Cabral Scabin

“…O artigo pretende contribuir para a compreensão das formas pelas quais são representados, em discursos produzidos por humoristas brasileiros, o lugar e o papel da categoria liberdade de expressão em relação às disputas por capital e às formas de distinção no campo do humor. …”
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Mapping of Novel QTL Regulating Grain Shattering Using Doubled Haploid Population in Rice (Oryza sativa L.) by Gyu-Ho Lee, In-Kyu Kang, Kyung-Min Kim

“…Several important genes are distributed in 1 Mbp region of the QTL on chromosome 6 and they are related to the formation of abscission layer. We decide to name this QTL qSh6 and the candidate genes in the qSh6 region can be employed usefully in further research for cloning.…”
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GIS and remote sensing based assessment of West Rapti River channel migration in Nepal by Sandesh Gharti, Prabin Poudel, Ramesh Silwal, Suchana Baniya, Jeetendra Gautam, Om Mishra, Sijan Bista, Dipendra Dhungana

“…These results are crucial for formulating integrated river basin management plans in the West Rapti River basin laying the foundation for future research to explore sustainable river management practices in the future.…”
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