Colorimetric aptasensor coupled with a deep-learning-powered smartphone app for programmed death ligand-1 expressing extracellular vesicles by Adeel Khan, Adeel Khan, Haroon Khan, Nongyue He, Zhiyang Li, Heba Khalil Alyahya, Yousef A. Bin Jardan

“…To transform the qualitative colorimetric approach into a quantitative operation, we developed an intelligent convolutional neural network (CNN)-powered quantitative analyzer for chromaticity in the form of a smartphone app named ExoP, thereby achieving the intelligent analysis of chromaticity with minimal user intervention or additional hardware attachments for the sensitive and specific quantification of PD-L1@EVs. …”
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A General Criterion for Unidirectionally Coupled Generalized Chaotic Synchronization with a Desired Manifold by Xiang Yu, Zhaolun Zuo, Shijian Zhu, Xuxin Zhang

“…Two numerical examples are used to construct unidirectional coupled chaotic systems in the form of different types of manifolds. Numerical simulation is carried out to verify the feasibility of the construction method and the criterion.…”
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METHODOLOGICAL APPROACHES TO DEVELOPMENT REGIONAL INTERACTION CENTER «GOVERNMENT-BUSINESS-SCIENCE» IN THE CONTEXT OF «TRIPLE HELIX» MODEL by V. Mikhaylov

“…The article describes the interaction mechanisms of external forms and methods of partnership of science/education, business and government in the context of «triple helix» model. …”
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Linguistic aspects of law: problems and prospects by S. P. Girenko, O. B. Overchuk, V. A. Pertseva

“…On the basis of a systematic analysis, the linguistic and legal research on the problem has been reviewed; the main vectors of domestic and foreign jurisprudence development with a projection on the linguistics of law have been identified; the issues of streamlining legal terminology, searching for interlingual equivalents and creating dictionaries of legal terms have been considered; the problems of combining theoretical and applied methods for qualitative linguistic examination of legal texts have been characterised; the positive and negative consequences of semantic and textual linguistic examinations of legal texts have been studied. …”
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Enhanced Beidou user equipment access authentication protocol based on location key by Jin CAO, Qiuyu BU, Yuanyuan YANG, Hui LI, Qiao LIU, Maode MA

“…In order to solve the shortcomings of the existing Beidou user equipment access solutions such as prolonged authentication, and in response to the need of user privacy protection, a user equipment access authentication protocol based on location key was proposed, which realized the mutual authentication and session key negotiation between entities.Combining Beidou’s location information and master key to form a two-factor, the proposed protocol solved the security problem of the master key leaking due to the equipment being captured during the authentication process to some extent.The proposed protocol can meet different security requirements through the verification of the Scyther formal tool.Compared with other similar schemes, it has better performance overhead, and is suitable for Beidou satellite navigation system with limited node resources.…”
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Association of genetic variations in the NOS1 gene with insomnia, sleep duration and obstructive sleep apnea-related clinical quantitative traits by YUAN Haolin, LI Niannian, HU Junhui, SHEN Jinhong, GAO Zhenfei, GUAN Jian, LIU Feng, YIN Shankai

“…Furthermore, we explored the relationships between rs7305526 and rs11615756 with clinical quantitative traits of OSA, such as respiratory events, oxygen levels, and sleep traits, using clinical monitoring data from the Shanghai Sleep Health Study Cohort (SSHS) based on standard polysomnography (PSG).Results·The NOS1 gene demonstrated elevated levels of expression in various brain regions crucial for regulating sleep, namely the amygdala, basal forebrain, striatum, and thalamus, as well as in the respiratory center, including the mesencephalon and pontine tegmentum. …”
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The Y-Index of Some Complement Graph Structures and Their Applications of Nanotubes and Nanotorus by Mohammed Alsharafi, Abdu Alameri, Yusuf Zeren, Mahioub Shubatah, Anwar Alwardi

“…Moreover, the Y-polynomial of titania nanotubes and the formulae for the Y-index, Y-polynomial, F-index, F-polynomial, and Y-coindex of the HAC5C7q,p and HAC5C6C7q,p nanotubes and their molecular complement graphs have been investigated.…”
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The Evaluation of Antibacterial Coatings Against Commonly Found Pathogenic Bacteria in the Environment—Implications for Environmental Safety and Infection Prevention by Wei-Chuan Chen, Mei-Hsiu Ho, Shin-Huan Yuan, Hui-Wen Chou, Chi-Chuan Chang, Chih-Hung Chen, Yusen Eason Lin

“…This study aimed to determine the antibacterial effect of two coating formulas against common environmental pathogens like <i>Escherichia coli</i>, <i>Staphylococcus aureus</i>, <i>Acinetobacter baumannii</i>, <i>Pseudomonas aeruginosa</i>, <i>Salmonella</i> sp., vancomycin-resistant <i>Enterococcus faecium</i>, and <i>Klebsiella pneumoniae</i>. …”
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Optimisation Design and Damping Effect Analysis of Large Mass Ratio Tuned Mass Dampers by Ying-jie Kang, Ling-yun Peng

“…The results show that when the mass ratio is large, the error between the existing fitting formula and the actual optimal value is quite large, and the revised fitting formula is applicable to the parameter design of the traditional small mass ratio and large mass ratio (≤1) TMDs. …”
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Antecedents and consequences of professional competence of school administrators with emphasis on environmental sustainability and sustainable development by mohamadreza rasouli, ghafar tari, hossein Baghaei

“…In the quantitative section, the Cochran formula with a five percent error level was used, and a sample size of 384 individuals was determined and selected using simple random sampling method. …”
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Non-linear oral bioavailability and clinical pharmacokinetics of high-dose Andrographis paniculata ethanolic extract: relevant dosage implications for COVID-19 treatment by Phanit Songvut, Jaratluck Akanimanee, Tawit Suriyo, Nanthanit Pholphana, Nuchanart Rangkadilok, Duangchit Panomvana, Porranee Puranajoti, Jutamaad Satayavivad

“…Further research is warranted to explore alternative extraction methods or formulation developments that can enhance the bioavailability of andrographolide and its potential therapeutic effects for COVID-19 treatment.…”
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El clero y los usos políticos de la Virgen del Quinche en la sierra centro-norte de Ecuador (1883-1914) by Luis Esteban Vizuete Marcillo

“…Se estudia, mediante manuscritos e impresos, el discurso del clero sobre esa Virgen, y las prácticas que este fomentó, ajustó y fortaleció conforme el contexto y el cambio en su postura lo requirieron. …”
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Retrospective analysis of exporting agricultural processing industry products by Yu. S. Lisachkina

“…At the same time, the share of processed food products in the total volume of domestic exports from 2014 to 2021 increased from 1.7 to 3.1%, which is a favorable factor in reducing the mineral-raw materials orientation of Russia’s foreign trade. The increase in processed products exports contributes to the export-oriented nature of the domestic food industry, which grew from 6.5 to 11.6 % over the period. …”
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With great power, comes great responsibility: the importance of broadly measuring Fc-mediated effector function early in the antibody development process by Silvia Crescioli, Shashi Jatiani, Lenny Moise

“…Building on many years of progress, the biopharmaceutical industry is now advancing innovative research and development by exploring new targets and new formats and using antibody engineering to fine-tune functions tailored to specific disease requirements. …”
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Processing of retransmitted GPS signals in the problem of measuring the total electron content in the ionosphere by Y. A. Kapliarchuk, S. V. Kozlov, I. E. Savinykh, A. S. Shapkin

“…Coherent accumulation, taking into account a random uncontrolled shift in the frequency of the retransmitted signal, is implemented by discrete Fourier transform of the vectors formed for each resolution element in the delay time from inter-period readings of the results of intra-period processing, taking into account the range migration during the mutual movement of the NS, SR and RP.Results. …”
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Corporate Pension Insurance as the Element of Human Resource Management by L. V. Anikeeva

“…We draw attention to reasons and conditions of corporate pension formation. There is the relation of pension rate and level of payment and way to ensure the percentage of reimbursement of pre-retirement income in the amount of pensions no lower than the level recommended by the minimum monthly wage. …”
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Evaluación y análisis visual de la postura corporal en pacientes con prótesis o dispositivos ortopédicos en los miembros inferiores by Mauricio Orlando Gómez, Carlos Filiberto Alfaro

“…Esto va a ayudar a los profesionales de la salud a comprender y analizar la forma en que los pacientes se posicionan y se mueven, lo que a su vez puede influir en el diseño y ajuste de las órtesis o prótesis, así como en el desarrollo de planes de tratamiento personalizados. …”
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Development and validation of an explainable machine learning model for mortality prediction among patients with infected pancreatic necrosisResearch in context by Caihong Ning, Hui Ouyang, Jie Xiao, Di Wu, Zefang Sun, Baiqi Liu, Dingcheng Shen, Xiaoyue Hong, Chiayan Lin, Jiarong Li, Lu Chen, Shuai Zhu, Xinying Li, Fada Xia, Gengwen Huang

“…Findings: Random survival forest (RSF) model showed the best predictive performance than other 9 ML models (internal validation, C-index = 0.863 [95% CI: 0.854–0.875]; external validation, C-index = 0.857 [95% CI: 0.850–0.865]). …”
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Hacia una ética transdisciplinaria de los estudios globales by Shu-Mei Shih

“…Este artículo busca intervenir en los límites disciplinarios que hasta ahora han impedido el intercambio de ideas significativo entre diferentes formaciones intelectuales en los estudios de «literatura universal», «historia mundial», «arte universal», «música mundial», «cine mundial» y demás, en un conglomerado bajo el nombre de «estudios globales». …”
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Abnormal directed migration of blood polymorphonuclear leukocytes in rheumatoid arthritis. Potential role in increased susceptibility to bacterial infections by F. Aglas, J. Hermann, G. Egger

“…The migration of PMNs from RA patients and controls was stimulated using the bacterial chemoattractant N-formyl-methionyl-leucylphenylalanine (fMLP). Unstimulated PMN migration of RA patients was increased compared with healthy controls as measured by the following parameters: (a) absolute number of migrant PMNs (1954 ± 87 vs. 1238 ± 58 PMN/mm2), (b) percentage of PMNs migrated into the filter (total migration index, TMI) (28.6 ± 0.9 vs. 24.0 ± 0.8 %), (c) the distance half the migrating PMNs had covered (distribution characteristic, DC) (22.6 ± 1.1 vs. 16.1 ± 0.6 mm) and (d) the product of TMI and DC (neutrophil migratory activity, NMA) (669.0 ± 45.0 vs. 389.0 ± 18.9). fMLP stimulated PMNs of RA patients showed defective migration compared to unstimulated samples as shown by (a) a reduced number of migrant PMNs (1799 ± 93 PMN/mm2), (b) lower TMI (26.1 ± 0.9 %), (c) unremarkable altered distribution characteristic (22.9 ± 0.8 mm) and (d) significant reduced migratory activity (600.0 ± 30.0). …”
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