Analysis of drug release models from biodegradable nanomodified chitosan based materials by М. О. Кумеда, Л. Б. Суходуб, Л. Ф. Суходуб

“…Objectives: Most forms of drug delivery systems demonstrate rapid release of ceftriaxone (CFT) and anasthesin (ANA) within 2 days, characterized by a "burst release" that may cause overdose in the first hours of use. The aim of this work was to investigate and compare the drug release kinetics from convectionally and MW-synthesized CS matrices modified with HA, multiphasic CaP, and fullerene C60 nanoparticles for long-term bone tissue regeneration. …”
Get full text

Validation of a B-type natriuretic peptide as a prognostic marker in pneumonia patients: a prospective cohort study by Yu Hashimoto, Daisuke Usuda, Ryusho Sangen, Emiri Muranaka, Yoshitsugu Iinuma, Tsugiyasu Kanda

“…In multivariable Cox-regression analysis, BNP remained an independent mortality predictor (HR 10.01, 95% CI 1.32 to 75.7, p=0.03) in CAP.Conclusions BNP levels may be a useful single prognostic marker for CAP. …”
Get full text

Abnormal dynamic functional networks during pain-free periods: Resting-state co-activation pattern analysis in primary dysmenorrhea by Huiping Liu, Xing Su, Meiling Shang, Ling Ma, Weixian Bai, Hui Wang, Lu Quan, Youjun Li, Zigang Huang, Jiaxi He, Wanghuan Dun, Yuchen Zhang

Get full text

Trend of Use of Quinolone Antibiotics in Community-Acquired Pneumonia by Kadir Burak AKGÜN, Emel CEYLAN, Mehmet KARADAĞ, Merve AYIK TÜRK

“…However, the relevant guidelines conflict with each other regarding their first-line of use in CAP. In addition, knowledge about the side effects of quinolones is increasing. …”
Get full text

Ocular inoculation of toad venom: toxic cataract and proteomic profiling by Danni Lyu, Danni Lyu, Shuang Ni, Shuang Ni, Jia Xu, Jia Xu, Sha Zhu, Sha Zhu, Jing-Wei Xu, Jing-Wei Xu, Yixuan Feng, Yixuan Feng, Ce Shi, Ce Shi, Wen Xu, Wen Xu

“…Specifically, a total of 204 DEPs were identified in PT_CAP compared to C_CAP, with MYH6, MYL2, MYL3, STAT1, and ANK1 among the foremost regulated DEPs. …”
Get full text

Retrograde Balloon Dilation outside the Main Branch Stent to Restore the Occlusion of Side Branch in Chronic Total Occlusion Bifurcation Lesions by Gao Hao-kao, Li Cheng-xiang

Get full text

Polymorphism of genes associated with infectious lung diseases in Northern Asian populations and in patients with community-acquired pneumonia by S. V. Mikhailova, L. V. Shcherbakova, N. I. Logvinenko, I. I. Logvinenko, M. I. Voevoda

“…The innate Iнн\mmune system is the first to respond to invading pathogens. It is responsible for invader recognition, immune-cell recruitment, adaptive-immunity activation, and regulation of inflammation intensity. …”
Get full text

Association between Smoking and Liver Fibrosis among Patients with Nonalcoholic Fatty Liver Disease by Hongjie Ou, Yaojie Fu, Wei Liao, Caixia Zheng, Xiaolu Wu

Get full text

Selected Biomarkers Correlate with the Origin and Severity of Sepsis by Michal Holub, Olga Džupová, Michaela Růžková, Alžběta Stráníková, Eva Bartáková, Jan Máca, Jiří Beneš, Heiko Herwald, Ondřej Beran

“…Therefore, the plasma levels of cytokines (IL-6, IL-8, and IL-10), chemokines (CCL2/MCP-1, MIP-1β), heparin-binding protein (HBP), soluble CD14 (sCD14), and cortisol were analyzed in blood from septic patients obtained during the first 96 hours of intensive care unit hospitalization. …”
Get full text

A vestige of FZZ duality in higher dimensions by Chethan Krishnan, Sarthak Talukdar

“…In this note, we observe that a similar re-writing exists in higher dimensions, so that the degree of the dilaton-winding subsystem reduces to first order. The 1+1 first order equations emerge as a natural limit of the higher dimensional HP system in the cap region of the cigar. …”
Get full text

Improvement on Structural Forms of Pile Group Foundations of Deepwater Bridges by Enbo Yu, Sen Ren, Haojun Tang, Yongle Li, Chen Fang

“…The wave theory and the method used for computing wave forces on foundations are first introduced. Then, a pile group foundation is taken as the research object, and different pile lengths ranging from 16 m to 46 m are considered. …”
Get full text

STUDY ON THE STRUCTURAL CHARACTERISTICS OF LARGE WIND TURBINE COMPOSITE BLADE BASED ON BEND-TWIST COUPLING by ZHANG Li, MIAO WeiPao, LI Chun, YAN YangTian, LIU QingSong, WANG Bo

“…The critical buckling load of spar cap-coupled blades have a large decrease, while other BTC blades have a slight increase, and the amount of the first-order buckling deformation is lower than traditional blades.…”
Get full text

Sleep stages classification based on feature extraction from music of brain by Hamidreza Jalali, Majid Pouladian, Ali Motie Nasrabadi, Azin Movahed

“…REM) is made with an accuracy of 90.1 % (Cap sleep database),88.9 % (Sleep-EDF database), 90.1 % (Sleep-EDF expanded database). …”
Get full text

Effects of Tributyrin Supplementation on Growth Performance, Intestinal Digestive Enzyme Activity, Antioxidant Capacity, and Inflammation-Related Gene Expression of Large Yellow Cr... by Xiuneng Wang, Min Wan, Zhen Wang, Haitao Zhang, Si Zhu, Xiufei Cao, Ning Xu, Jichang Zheng, Xianyong Bu, Wei Xu, Kangsen Mai, Qinghui Ai

“…An 8-week growth experiment was conducted to investigate effects of tributyrin (TB) supplementation on growth performance, intestinal digestive enzyme activity, antioxidant capacity, and inflammation-related gene expression of juvenile large yellow croaker (Larimichthys crocea) (initial weight of 12.90±0.02 g) fed diets with high level of Clostridium autoethanogenum protein (CAP). In the negative control diet, 40% fish meal was used as the major source of protein (named as FM), while 45% fish meal protein of FM was substituted with CAP (named as FC) to form a positive control diet. …”
Get full text

The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis by Song Hu, Yundong Wang, Hongbing Li

“…In recent years, studies have found that the body’s cholinergic system can spontaneously and dynamically regulate inflammation and immunity in sepsis according to the needs of the body. Firstly, the vagus nerve senses and regulates local or systemic inflammation by means of the Cholinergic Anti-inflammatory Pathway (CAP) and activation of α7-nicotinic acetylcholine receptors (α7nAChRs); thus, α7nAChRs play important roles for the central nervous system (CNS) to modulate peripheral inflammation; secondly, the activation of muscarinic acetylcholine receptors 1 (M1AChRs) in the forebrain can affect the neurons of the Medullary Visceral Zone (MVZ), the core of CAP, to regulate systemic inflammation and immunity. …”
Get full text

Translational Modulation of Proteins Expressed from Bicistronic Vectors by Prasun J. Mishra, Lata G. Menon, Pravin J. Mishra, Philipp Mayer-Kuckuk, Joseph R. Bertino, Debabrata Banerjee

“…Using rapamycin pretreatment followed by MTX treatment, we also devised a strategy to modulate levels of two proteins expressed from a bicistronic construct in a cap-independent manner. To our knowledge, this is the first report demonstrating that levels of proteins in DHFR-based bicistronic constructs can be induced and modulated using MTX and rapamycin treatment.…”
Get full text

Chimen an nou, une carte contributive pour se rapprocher du territoire by Bertilla Baudinière, Jeanne Lacour

“…Chimen an nou is intended to develop the practice of walking and cycling on a daily basis in the area of the conurbation of Cap Excellence in Guadeloupe. A contributory digital tool was combined with fieldwork and public events to disseminate sensory knowledge of the territory and invite people to experiment with new ways of getting around. …”
Get full text

Thermospheric Wind Response to March 2023 Storm: Largest Wind Ever Observed With a Fabry‐Perot Interferometer in Tromsø, Norway Since 2009 by S. Oyama, H. Vanhamäki, L. Cai, A. Shinbori, K. Hosokawa, T. Sakanoi, K. Shiokawa, A. Aikio, I. I. Virtanen, Y. Ogawa, Y. Miyoshi, S. Kurita, N. Nishitani

“…On March 24, the first day of the storm recovery phase, thermospheric wind disturbed and the ionospheric density decreased significantly at high latitudes. …”
Get full text

IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome by Min Guo, Rui Yan, Hongmei Yao, Liqin Duan, Meng Sun, Zheng Xue, Yongping Jia

Get full text

Infinitely many solutions for an anisotropic differential inclusion on unbounded domains by Giovany Figueiredo, Abdolrahman Razani

“…By establishing the existence of infinitely many solutions, we achieve a first result within the anisotropic framework.…”
Get full text