Emotion dysregulation in adolescents is normalized by ADHD pharmacological treatment by Krisztina Kondi, Mária Takács, Evelyn Kovács-Posta, Claudia Szajli, Tünde Sebők-Welker, János M. Réthelyi, Nóra Bunford

“…Abstract Background Attention-deficit/hyperactivity disorder (ADHD) is associated with emotion dysregulation (ED) and in ADHD, beyond ADHD and comorbidity severity, ED confers increased risk for negative outcomes. First- and second-line ADHD pharmacotherapy is effective at ameliorating core symptoms and improving cognitive functioning and accumulating evidence indicates primairly in children and adults, active ADHD pharmacotherapy has beneficial effects on emotional symptoms. …”
Get full text

Real-World Parkinson’s Hand Tremor Detection Using Ensemble Learning Techniques by Sungwook Hur, Jieming Zhang, Moon-Hyun Kim, Tai-Myoung Chung

“…The results of our five-fold cross-validation experimental evaluation using the PD-BioStampRC21 dataset show that our method achieved an accuracy of 86.67% and an AUC score of 95.56%, representing a significant improvement over the baseline model’s accuracy of 72.67% and surpassing other existing methods. …”
Get full text

Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model by Frida Wilske, Olof Eriksson, Rose-Marie Amini, Sergio Estrada, Helena Janols, Amina Khalil, Anders Larsson, Miklós Lipcsey, Sara Mangsbo, Jonathan Sigfridsson, Jan Sjölin, Paul Skorup, Anders Wall, Viola Wilson, Markus Castegren, Gunnar Antoni

“…Repeated PET–CT investigations were performed before and after induction of sepsis. Results At baseline [11C]NES uptake was found in the bone marrow, spleen and liver. …”
Get full text

Insights from serial cardiovascular magnetic resonance imaging show early progress in diastolic dysfunction relates to impaired right ventricular deformation by Sören J. Backhaus, Alexander Schulz, Torben Lange, Simon F. Rösel, Lennart S. Schmidt-Schweda, Shelby Kutty, Johannes T. Kowallick, Julia Treiber, Andreas Rolf, Samuel Sossalla, Gerd Hasenuß, Andreas Schuster

“…Clinicaltrials.gov: NCT03260621 (First posted date 24/08/2017).…”
Get full text

Joint Distribution pada Weighted Majority Vote (WMV) untuk Peningkatan Kinerja Sentiment Analysis Tersupervisi pada Dataset Twitter by Bagus Setya Rintyarna

“…Selanjutnya kinerja weighted majority vote secara ekstensif dibandingkan dengan 4 metode baseline sebagai pembanding, yaitu: Naïve Bayes, Gaussian Naïve Bayes, Multinomial Naïve Bayes dan Majority Vote dari ketiga single classifier tersebut. …”
Get full text

Acute and chronic effects of physical exercise on atherosclerosis, kynurenine pathway, endothelial function and inflammation in patients with coronary artery disease: a clinical tr... by Eliete Bouskela, Gabriela Andrade Paz, Marcus VDS Rangel, Caio Luan Farias, André Luiz Conveniente Soares, Erica Langner, Tatiana Teixeira, Patrícia M L Dutra, Paulo Farinatti, Maria das Graças C Souza, Juliana P Borges

“…Evaluations will occur at baseline and post-intervention. On the first visit, carotid artery thickness will be assessed via ultrasound before and after cardiopulmonary exercise testing. …”
Get full text

Automatic cervical lymph nodes detection and segmentation in heterogeneous computed tomography images using deep transfer learning by Wenjun Liao, Xiangde Luo, Lu Li, Jinfeng Xu, Yuan He, Hui Huang, Shichuan Zhang

Get full text

Protocol of the Nurses’ Mental Health Study (NMHS): a nationwide hospital multicentre prospective cohort study by Jiaxin Yang, Chongmei Huang, Shuiyuan Xiao, Xuting Li, Meng Ning, Zengyu Chen, Yusheng Tian, Qiang Yu, Yamin Chen, Ya-Min Li

Get full text

Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab by Hans-Christoph Diener, Kathleen A. Day, Sarah Lipsius, Sheena K. Aurora, Nada A. Hindiyeh, Holland C. Detke

“…Trial registration Clinicaltrials.gov NCT02614261, first registered November 25, 2015.…”
Get full text

Age-related changes in DNA methylation in a sample of elderly Brazilians by Hayley Welsh, Caio M. P. F. Batalha, Weili Li, Nadja C. Souza-Pinto, Yeda A. O. Duarte, Michel S. Naslavsky, Esteban J. Parra

“…Using mixed-effects models, we examined changes in DNAm patterns using both quantitative age and binary timepoint (e.g., baseline vs. follow-up) as predictors of interest to identify differentially methylated positions (DMPs). …”
Get full text

Derivation of a simple risk calculator for predicting clinical worsening in patients with pulmonary hypertension due to interstitial lung disease by K. El-Kersh, R. Bag, N. Bhatt, C. King, A. Waxman, F. Rischard, H. Kim, D. Cella, E. Shen, SD Nathan

“…Methods: The INCREASE study was a 16-week study that evaluated inhaled treprostinil in patients with ILD-PH. Baseline data from patients who were randomized to the placebo arm (n=163) and thus untreated with any approved pulmonary artery vasodilators were used to derive a risk calculator. …”
Get full text

Weight loss-independent changes in human growth hormone during water-only fasting: a secondary evaluation of a randomized controlled trial by Benjamin D. Horne, Benjamin D. Horne, Benjamin D. Horne, Jeffrey L. Anderson, Jeffrey L. Anderson, Heidi T. May, Tami L. Bair, Viet T. Le, Viet T. Le, Leslie Iverson, Kirk U. Knowlton, Kirk U. Knowlton, Joseph B. Muhlestein, Joseph B. Muhlestein

“…HGH, weight, and other parameters were measured at baseline and at the end of the first and second days.ResultsBaseline HGH had median 0.50 ng/mL for females (n=20) and 0.04 ng/mL for males (n=10), and correlated inversely with weight, glucose, insulin, and triglycerides and positively with changes in insulin and HOMA-IR. …”
Get full text

Effect of the cervical and thoracic “Daoyin” training on posture and pulmonary function in patients with upper crossed syndrome: a randomized controlled trial by Yue Guo, Ming Li, Chaowei Xie, Xiaoyan Liu, Yushan Chen, Jun Yang, Yuxue Wu, Shaoqing Chen, Shizhong Wang, Jianping Lin

Get full text

The Effect of Vitamin D3 on Serum Creatine Phosphokinase Level in Patients with Multiple Trauma: A Pilot Randomized Clinical Trial by Mehran Kouchek, Niloufar Taherpour, Mahya Farasat, Mirmohammad Miri, Sara Salarian, Seyedpouzhia Shojaei, Rezvan Hassanpour, Hossein Amini, Mohammad Sistanizad

“…Conclusion: The current study revealed that vitamin D3, could prevent the increasing trend of CPK during the first days and accelerate the normalization of CPK in patients with elevated CPK due to multiple trauma.Trial registration number: IRCT20120703010178N23.…”
Get full text

Accelerated aging as a mediator of the association between co-exposure to multiple air pollutants and risk of chronic kidney disease by Shuo Zhang, Yuxin Liu, Jike Qi, Yu Yan, Tongyu Gao, Xin Zhang, Dong Sun, Ting Wang, Ping Zeng

“…Methods: Using a cohort of 313,908 participants without CKD at baseline from the UK Biobank, we examined the potential association between co-exposure to multiple air pollutants, including PM2.5, PM10, PM2.5–10, NO2 and NOx, and the incidence of CKD by calculating an air pollution score. …”
Get full text

A novel early stage drip irrigation system cost estimation model based on management and environmental variables by Masoud Pourgholam-Amiji, Khaled Ahmadaali, Abdolmajid Liaghat

“…A database (a matrix of 515 × 43) was created, and the costs of all projects were updated for the baseline year of 2022. Then, several feature selection algorithms, such as WCC, LCA, GA, PSO, ACO, ICA, LA, HTS, FOA, DSOS, and CUK, were employed to choose the most significant features that had the biggest influence on the system cost. …”
Get full text

Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial by Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez, Natalia Garcia-Giralt

“…The primary outcome was to evaluate the absolute change in questionnaire scores between baseline and two follow-up points: immediately after balneotherapy (or one-month post-baseline for the control group) and 2 months post-baseline. …”
Get full text

Consecutive prediction of adverse maternal outcomes of preeclampsia, using the PIERS-ML and fullPIERS models: A multicountry prospective observational study. by Guiyou Yang, Tünde Montgomery-Csobán, Wessel Ganzevoort, Sanne J Gordijn, Kimberley Kavanagh, Paul Murray, Laura A Magee, Henk Groen, Peter von Dadelszen

“…The main limitation of this study is that the baseline performance of the PIERS-ML model was assessed on its development data; however, its baseline performance has also undergone external evaluation.…”
Get full text

Zooarchaeological investigation of the Hoabinhian exploitation of reptiles and amphibians in Thailand and Cambodia with a focus on the Yellow-headed Tortoise (Indotestudo elongata... by Bochaton, Corentin, Chantasri, Sirikanya, Maneechote, Melada, Claude, Julien, Griggo, Christophe, Naksri, Wilailuck, Forestier, Hubert, Sophady, Heng, Auertrakulvit, Prasit, Bowonsachoti, Jutinach, Zeitoun, Valéry

“…Additionally, we provide a baseline for future zooarchaeological studies and a methodological framework for the detailed analysis of archaeological turtle bones in continental Southeast Asia. …”
Get full text

Exploring the impact and mechanisms of behavioral activation on sleep disorders in colorectal cancer: a randomized controlled trial by Anlong Li, Runze Huang, Han Ge, Dajie Liu, Shaochun Liu, Yingxue Jia, Jiaying Chai, Xinyi Zheng, Lijun Liu, Chen Gan, Jian Xu, Ling Cheng, Mingjun Zhang, Huaidong Cheng

“…Cognitive behavioral therapy for insomnia (CBT-I) is considered the first-line treatment but is often complex, costly, and requires highly trained therapists. …”
Get full text