Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled t... by Torben Hansen, Tina Vilsbøll, Filip Krag Knop, Alexander Sidelmann Christensen, Heidi Storgaard, Sofie Hædersdal

“…Sulfonylurea (SU) is used as a first-line therapy in HNF1A-diabetes. However, SU therapy may be problematic as it confers a high risk of hypoglycaemia. …”
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Length-weight relationship, condition factors and reproductive biology of the spineless cuttlefish Sepiella inermis (Ferussac & d’Orbigny, 1848) in the southeastern regions of... by Roksana Jahan, Md. Nasim Mahmud

“…Sepiella inermis, spineless and small-size cuttlefish, is one of the important species of cephalopods and widely distributed in the Indo-west Pacific region. This study, for the first time in the southeastern region of the Bay of Bengal, Bangladesh, was conducted to investigate the length-weight relationship, condition factors and spawning season of S. inermis. …”
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Radiographic Evaluation of The Bone Density Around Tooth-Anchored One-Piece Immediate-Loading Dental Implant by Bangen Mohammed Karam, Bahar Jaafar Selivany, Huda Jameel Qasim, Rafah Hussein Mohammed

“…Cone beam computed tomography (CBCT) was used for treatment planning, and intra-oral digital radiographs were taken at baseline (T0), six months (T1), and one year (T2). …”
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The Effects of Adverse Events and Associated Costs on Value-Based Care for Metastatic Pancreatic Ductal Adenocarcinoma by Prachi Bhatt, Jared Hirsch, Paul Cockrum, George Kim, Gabriela Dieguez

“…**Objectives:** To compare the incidence of adverse events (AEs), AE-associated excess costs, and total cost of care (TCOC) of 3 cohorts receiving first-line treatment for metastatic pancreatic ductal adenocarcinoma (mPDAC). …”
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Spatiotemporal clusters of acute respiratory infections associated with socioeconomic, meteorological, and air pollution factors in South Punjab, Pakistan by Munazza Fatima, Ibtisam Butt, Shahab MohammadEbrahimi, Behzad Kiani, Oliver Gruebner

“…In addition, this study provides the first baseline of ARI cases in Pakistan to plan for intervention and adaptation strategies and may be replicated in other regions of comparable settings worldwide.…”
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The antimicrobial susceptibility patterns of diabetic foot ulcers in the South African public healthcare sector by M J Turner, S Leigh-de Rapper, T P Mokoena, S van Vuuren

“…Amoxicillin/clavulanic acid, the first-line treatment according to the STGs, was found to be ineffective for many of the isolated pathogens. …”
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Impact of parathyroidectomy on inflammatory and cardiovascular risk parameters in primary hyperparathyroidism: a retrospective analysis by Nese Bulbul, Suat Sen, Fettah Acibucu

“…Conclusion Our findings highlight a potential link between PHPT and inflammatory-cardiovascular risk, with parathyroidectomy exerting a beneficial effect within the first month post-surgery. The study also suggests that these risk factors may be modifiable with timely surgical intervention. …”
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Analysis of Air Pollution Data in India between 2015 and 2019 by Disha Sharma, Denise Mauzerall

“…Our dataset also provides a baseline to evaluate the future success of National Clean Air Programme as well as aids in assessment of existing and future air pollution mitigation policies.…”
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Atopic Dermatitis Treatments Before and After Initiation of Ruxolitinib Cream: 6-Month Follow-Up Analysis of a US Payer Claims Database by Liu J, Desai K, Teng CC, Sturm D, Stockbower G, Patadia H, Willey V

“…Data from 6 months before ruxolitinib cream initiation (baseline period) and after initiation (follow-up period) were summarized using descriptive statistics.Results: Of 1,581 patients in the overall AD cohort, 749 had a history of more advanced AD therapy. …”
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Effect of arm-ergometry versus treadmill supervised exercise on health-related quality of life and mental health in patients with peripheral artery disease: secondary outcomes from... by Sandra Magalhães, Mário Santos, Sofia Viamonte, Fernando Ribeiro, Joana Martins, Cristine Schmidt, Henrique Cyrne-Carvalho

“…Differences between groups in the change from baseline to the end of the study were analyzed using ANCOVA, adjusted for baseline values, or the Mann-Whitney U test. …”
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Oral dydrogesterone versus oral micronized progesterone in threatened miscarriage: protocol paper for a randomized controlled trial by Alka Kriplani, Gouri Shankar Kamilya, T Ramani Devi, Ashima Taneja, Amol Pawar, Gayathri Karthik Nagesh, Tapan Pattanaik, Tanusree Gupta, Mahima Jain, Monjori Mitra

“…Threatened miscarriage is a common complication of early pregnancy characterized by symptoms of vaginal bleeding with/without abdominal cramps/pain in the first trimester. Progestogens are often administered for the management of this condition. …”
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Electrogastrogram-based detection of cybersickness with the application of wavelet transformation and machine learning: A case study by Ilija V. Tanasković, Nenad B. Popović, Jaka J. Sodnik, Sašo J. Tomažič, Nadica S. Miljković

“…Furthermore, the paper investigates recovery from CS following VR and examines the application of unsupervised machine learning (ML) for segmenting EGG into baseline and CS, utilizing significant features previously identified. …”
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Clinical course of patients relisted for orthotopic heart transplantation: A national study by David Rekhtman, BS, Amit Iyengar, MD, MSE, Nikhil Ganjoo, BA, Cindy Song, BA, Noah Weingarten, MD, Max Shin, MD, Michaela Asher, MPhil, John DePaolo, MD, PhD, Marisa Cevasco, MD, MPH, Pavan Atluri, MD

“…We sought to describe the baseline characteristics, outcomes, and hospital selection of relisted patients by comparing their clinical status at the time of initial and subsequent listing. …”
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Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial by Xue Gao, Lu Liu, Mei-Rong Pan, Hai-Mei Li, Yu-Feng Wang, Xue-Ying Liu, Zhong-Fang Fu, Qiujin Qian

“…Participants will be assessed at baseline (T1), week 4 (T2), week 8 (T3), post-treatment (T4) and 3 month follow-up (T5).Discussion This protocol outlines the first randomised controlled trial investigating the efficacy of the UP-A among Chinese adolescents with emotional disorders. …”
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An Efficient and Hybrid Deep Learning-Driven Model to Enhance Security and Performance of Healthcare Internet of Things by Muhammad Babar, Muhammad Usman Tariq, Basit Qureshi, Zabeeh Ullah, Fahim Arif, Zahid Khan

“…In this method, we have first considered SDN architecture as a promising solution since it allows for reconfiguration over static network infrastructure and manages the distributed architecture of intelligent H-CIoT networks by keeping the data and control planes apart. …”
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Efficacy and safety of once-weekly semaglutide monotherapy in a young subject with Prader-Willi syndrome, obesity, and type 2 diabetes: a case report by Elisa Dinoi, Giuseppe Daniele, Giuseppe Daniele, Angela Michelucci, Fulvia Baldinotti, Fabrizio Campi, Piero Marchetti, Stefano Del Prato, Angela Dardano, Angela Dardano

“…However, data on their use in PWS are scarce.Case descriptionIn 2019, a 27-year-old male came to our Clinic because of first appearance of severe hyperglycemia (fasting plasma glucose 22.5 mmol/L). …”
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Hospitalisation from seasonal influenza among persons with type 1 diabetes: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Björn Eliasson, Hanne Krage Carlsen, Lena Svensson, Magnus Gisslén, Elin Allansson Kjölhede, Oliver Martyn

“…Persons with T1D had an unadjusted HR 4.7 (95% CI 4.0 to 5.5) for risk of hospitalisation from influenza during the study period and HR 3.4 (95% CI 2.9 to 4.0) when adjusted for age, sex, socioeconomic factors and chronic medical conditions at baseline. Within the T1D cohort, individuals hospitalised due to influenza were older, were more often smokers, had lower glomerular filtration rate and more often had a previous history of ischaemic heart disease and stroke.Conclusions To our knowledge, this is the first large study to highlight that persons with T1D have a threefold higher risk of hospitalisation due to seasonal influenza compared with matched controls from the general population. …”
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Real-World Assessment of Weight Change in African American Females and Hispanics with HIV-1 After Initiating Integrase Strand-Transfer Inhibitors or Protease Inhibitors by Yen-Wen Chen, David Anderson, Christopher D. Pericone, Prina Donga

“…Female African Americans or Hispanics initiating INSTI- or PI-based regimens between January 1, 2015, and December 31, 2018 (first prescription was index date), with ≥12-month baseline and follow-up periods, ≥1 weight measure during each period, and no prior antiretroviral (ARV) use were included. …”
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Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY stud... by Fuminori Taniguchi, Motoko Fukui, Yutaka Osuga, Tasuku Harada, Jo Kitawaki

“…Progestin preparations, such as dienogest, are the first-line therapy for endometriosis symptoms, but may cause abnormal uterine bleeding. …”
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Long term cost-effectiveness analysis of IDegLira in the treatment of type 2 diabetes patients compared to GLP-1RA added to basal insulin after IDegLira entered the national reimbu... by Dunming Xiao, Junling Weng, Lei Zhang, Chang Xing, Yan Wei, Yingyao Chen

“…<h4>Background</h4>Degludec insulin liraglutide injection is the world's first and only approved basal insulin GLP-1RA injection in China (GLP-1RA stands for Glucagon-Like Peptide-1 Receptor Agonist. …”
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