Effectiveness and safety of the XEN45 gel stent compared to trabeculectomy in primary open-angle glaucoma: the Gold-Standard Pathway Study by Kaweh Mansouri, Xuemin Gu, Ingeborg Stalmans, Herbert A Reitsamer, Iqbal K Ahmed, Vanessa Vera, Antonio Maria Fea, Earl Randy Craven

“…Visual recovery was faster/better (per the mean and time to first return to baseline best corrected visual acuity) and SHPC-18-related improvements were greater post-gel stent than post-trabeculectomy.Conclusion Similar proportions of eyes with POAG achieved the primary endpoint post-gel stent and post-trabeculectomy. …”
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Temporal changes in prevalence and severity of pulmonary hypertension, and relationship to outcomes in coarctation of aorta by Ahmed Younis, Yogesh N.V. Reddy, William R. Miranda, Ahmed T. Abdelhalim, Barry A. Borlaug, Heidi M. Connolly, Alexander C. Egbe

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Association of Race and Major Adverse Cardiac Events (MACE): The Atherosclerosis Risk in Communities (ARIC) Cohort by Ericha G Franey, Donna Kritz-Silverstein, Erin L Richard, John E Alcaraz, Caroline M Nievergelt, Richard A Shaffer, Vibha Bhatnagar

“…Included in this longitudinal study were 12,770 black or white participants from the Atherosclerosis Risk in Communities (ARIC) cohort who completed a baseline visit (1987–1989) with PON genotyping. Demographic, behavioral, and health information was obtained at baseline. …”
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Depression Following Thrombotic Cardiovascular Events in Elderly Medicare Beneficiaries: Risk of Morbidity and Mortality by Christopher M. Blanchette, Linda Simoni-Wastila, Fadia T. Shaya, Denise Orwig, Jason Noel, Bruce Stuart

“…Time to death and first recurrent TCE were assessed using descriptive and multivariate statistics. …”
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Clinical trial participation, clinical care, and patient outcomes by practice setting: a real-world database analysis of patients with Chronic Lymphocytic Leukemia or Mantle Cell L... by Debora S. Bruno, Manoj Khanal, Xiaohong Li, Maricer P. Escalon, Katherine Winfree, Lisa M. Hess

“…Cox proportional hazards regression model was used to adjust for baseline covariates.Results A total of 6,372 patients with CLL and 3,411 with MCL met eligibility criteria for this analysis; 13.9% and 22.2%, respectively, were treated in academic settings. …”
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The Effects of Pilot Structure on the Lean Ignition Characteristics of the Internally Staged Combustor by Zhengyan Guo, Yan Lu, Jingtao Yuan, Pimin Chen, Qibin Zhang, Wei Fan

“…Under the typical working conditions (the air mass flow rate is 46.7 g/s and the ignition energy is 4 J), for a pilot swirler with a rotating direction opposite to the main swirler, the diameter of the auxiliary fuel nozzles is 0.2 mm, the swirl number of first-stage of pilot swirler is 1.4, and the lean ignition fuel–air ratio was reduced to 0.0121, which is 32.78% lower than the baseline scheme, which further broadens the lean ignition boundary of the centrally staged combustion chamber.…”
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Longitudinal Assessment of Pain in Rheumatoid Arthritis: Increases in Pain and Their Relationship to Functional Declines and Medication Changes by Hallie M. Altwies, Leah M. Santacroce, Javier Marrugo, Jacklyn Stratton, Jack Ellrodt, Robert S. Rudin, Daniel H. Solomon

“…The median number of pain interference PROs answered per patient was 37 over 52 weeks. Using the first five pain interference PRO responses as the baseline, 60 (72%) patients experienced worsening of at least the MCID, with a median duration of 16 days. …”
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Systemic Factors Associated with Treatment Response in Diabetic Macular Edema by Wendy Meihua Wong, Caroline Chee, Mayuri Bhargava, Charmaine Chai, Hazel Lin, Paul Zhao, Erlangga Ariadarma Mangunkusumo, Thet Naing, Yew Sen Yuen, Tien Yin Wong, Xinyi Su, Gopal Lingam

“…Better glycemic control is associated with a greater reduction in central macular thickness after the first injection of bevacizumab or ranibizumab in diabetic macular edema. …”
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Long-term cardiac MRI follow up of MANTICORE (Multidisciplinary Approach to Novel Therapies in Cardio-Oncology REsearch) by Dina Labib, Mark Haykowsky, Emer Sonnex, John R. Mackey, Richard B. Thompson, D. Ian Paterson, Edith Pituskin

“…We posit that the presence of HER2 overexpressing breast cancer influenced hypertrophic changes to cardiac geometry observed at baseline and one year, which resolved after completing HER2-blocking treatment. …”
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The influence of gender and waist circumference in the association of body fat with cardiometabolic diseases by Milad Bagheri, Mehran Nouri, Ali Kohanmoo, Reza Homayounfar, Masoumeh Akhlaghi

“…We investigated the association between body fat percentage (BF%), as an appropriate indicator of obesity, and prevalence of cardiometabolic diseases using baseline data of Fasa PERSIAN cohort study. Methods The cross-sectional study was performed on data obtained at the first phase of the Fasa cohort study in Iran (n = 4658: M/F: 2154/2504). …”
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Sublingual Buprenorphine and Methadone Maintenance Treatment: A Three-Year Follow-Up of Quality of Life Assessment by Salvatore M. Giacomuzzi, Markus Ertl, Georg Kemmler, Yyvonne Riemer, Alexander Vigl

“…Urine tests were carried out randomly to detect additional consumption. In the first study period, 53 opioid-dependent subjects were enrolled and 25 could be reached after 3 years. …”
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Effect of the Interaction between Depression and Sleep Disorders on the Stroke Occurrence: An Analysis Based on National Health and Nutritional Examination Survey by Jia Li, Leijun Li, Yan Lv, Yanhai Kang, Mingjin Zhu, Wenfeng Wang

“…Univariate analysis was first performed between the stroke and nonstroke patients, and then, multivariate logistic regression models were conducted to analyze the association of depression, sleep disorders, and their interactions with stroke occurrence. …”
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Topic-aware neural attention network for malicious social media spam detection by Maged Nasser, Faisal Saeed, Aminu Da’u, Abdulaziz Alblwi, Mohammed Al-Sarem

“…Using dataset 1, the proposed model outperformed the baseline techniques, with average improvements in recall, precision, and F1 and accuracies of 17.54 %, 6.19 %, 11.91 %, and 12.27 %, respectively. …”
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Functional MRI-guided microsurgery of intracranial arteriovenous malformations: study protocol for a randomised controlled trial by Shuo Wang, Yuanli Zhao, Jun Wu, Bing Zhao, Yong Cao

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Effects of interleukin-12/23 inhibitors and interleukin-17 inhibitors on myocardial functions in patients with severe psoriasis by Leyla Baykal Selçuk, Mursel Şahin, Burcu Aydemir, Deniz Aksu Arıca, Savaş Yaylı

“…No significant changes in biochemical metabolic parameters were observed in any groups during the first year of treatment. A significant improvement in left ventricular global strain was observed in the ustekinumab, secukinumab, and ixekizumab groups compared to baseline (p<0.001, p=0.005, and p<0.001, respectively). …”
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Facilitating automated fact-checking: a machine learning based weighted ensemble technique for claim detection by Md. Rashadur Rahman, Rezaul Karim, Mohammad Shamsul Arefin, Pranab Kumar Dhar, Gahangir Hossain, Tetsuya Shimamura

“…Evaluation metrics showcased that the proposed weighted ensemble approach outperformed all baseline models, achieving a maximum F1 score of 0.87. …”
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Development of an mPBPK machine learning framework for early target pharmacology assessment of biotherapeutics by Krutika Patidar, Nikhil Pillai, Saroj Dhakal, Lindsay B. Avery, Panteleimon D. Mavroudis

“….), and virtual target candidates with varying characteristics (baseline expression, half-life, etc.) to unravel rules for antibody drug candidate selection that achieve favorable drug-target interaction, which is defined by target occupancy (TO) percentage. …”
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SleepNow – A combined cognitive behavioral therapy for insomnia and physical exercise intervention in men with metastatic prostate cancer: results from a feasibility randomized con... by Beverley Lim Høeg, Katrine Bjerre Løppenthin, Josée Savard, Christoffer Johansen, Jesper Frank Christensen, Mads Nordahl Svendsen, Niels Holländer, Pernille Envold Bidstrup

“…We assessed feasibility and measured objective and patient-reported outcomes at baseline and 3-months follow-up. Changes in both groups were compared using the Wilcoxon test. …”
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YOLO-IRS: Infrared Ship Detection Algorithm Based on Self-Attention Mechanism and KAN in Complex Marine Background by Limin Guo, Yuwu Wang, Muran Guo, Xiaohai Zhou

“…The model introduces the following optimizations: First, to address the difficulty of detecting weak and small targets, the Swin Transformer is introduced to extract features from infrared ship images. …”
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Oral Hygiene in Children with Autism: Teaching Self-Toothbrushing via Behavioural Intervention Including Parents by Marco Esposito, Carlotta Piersanti, Roberta Fadda, Marco Boitani, Monica Mazza, Giuseppina Marrocco

“…In this study, the efficacy is explored of a behavioral intervention mediated by staff and parents in teaching self-brushing teeth in eight autistic children. First, we wanted to examine whether the intervention improved self-brushing teeth skills in a short-term period. …”
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