Fluid accumulation syndrome in sepsis and septic shock: pathophysiology, relevance and treatment—a comprehensive review by Carmen Andrea Pfortmueller, Wojciech Dabrowski, Rob Wise, Niels van Regenmortel, Manu L. N. G. Malbrain

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Association of alcohol abstinence with risk of hyperuricemia in rural Chinese adults: the Henan Rural Cohort Study by Xiaokang Dong, Lulu Zhang, Ning Kang, Huanxiang Zhang, Wei Liao, Xiaotian Liu, Pengling Liu, Lei Yin, Chongjian Wang

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Efficacy and safety of immunotherapy in locally advanced or metastatic pulmonary lymphoepithelioma-like carcinoma: a multicenter retrospective study by Xiongwen Yang, Yi Xiao, Yubin Zhou, Hao Hu, Huiyin Deng, Jian Huang, Maoli Liang, Zihao Yuan, Longyan Dong, Shaohong Huang

“…Results: Chemoimmunotherapy significantly improved both PFS and OS compared to chemotherapy alone, in both first- and second-line settings. In first-line treatment, chemoimmunotherapy resulted in a median PFS of 17.6 months and OS of 26.1 months, compared to chemotherapy alone (PFS 8.7 months, OS 19.2 months). …”
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BIPOC Community Perspectives on Environmental Justice in Georgia by Stephanie Cho, LP Green, Marianne Chung, Julia Lee-Hong, Darlene Xiomara Rodriguez

“…This survey establishes a baseline understanding of these communities’ current perceptions, needs, practices, and potential localized solutions. …”
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Efficacy of Abiraterone and Enzalutamide in Pre- and Postdocetaxel Castration-Resistant Prostate Cancer: A Trial-Level Meta-Analysis by Mike Fang, Mary Nakazawa, Emmanuel S. Antonarakis, Chun Li

“…We examined the comparative efficacies of first-line abiraterone and enzalutamide in pre- and postdocetaxel settings in castration-resistant prostate cancer (CRPC) through a trial level meta-analysis. …”
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The Effects of Self-Monitoring Using a Smartwatch and Smartphone App on Stress Awareness, Self-Efficacy, and Well-Being–Related Outcomes in Police Officers: Longitudinal Mixed Desi... by Herman Jaap de Vries, Roos Delahaij, Marianne van Zwieten, Helen Verhoef, Wim Kamphuis

“…The data of 79 participants were included for analysis. During the first 5 weeks, participants used no self-monitoring technology (control period). …”
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Evaluation of the Clinical Efficacy of Prednisolone in the Treatment of Inflammatory Bowel Diseases with Different Dosage Methods by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…Two efficiency functions were constructed, compared and analyzed: the first — at the initial dosage of prednisolone in mg and the second calculating the dose in mg/kg of patient weight. …”
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Pyelonephritis and Bacteremia Caused by Klebsiella variicola following Renal Transplantation by Cody Lo, Shazia Masud, Gregory D. Deans

“…Hospitalization with acute pyelonephritis within the first year following kidney transplant is common and is associated with increased risk of graft loss and mortality. …”
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Barriers and facilitators for social inclusion among people with concurrent mental health and substance use problems. A qualitative scoping review. by Silje Nord-Baade, Ottar Ness, Camilla Bergsve Jensen, Michael Rowe, Elin Opheim, Anne Landheim

“…<h4>Methods</h4>We explored first-person perspectives on social inclusion among people with concurrent mental health and substance use problems, employing Arksey and O'Malleys framework. …”
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Phenobarbital as an adjunctive agent for sedation in pediatric intensive care unit patients: A single-center, retrospective study from Colorado by Kelli Jo Welter, Mackenzie N. DeVine, Sharon E. Gordon, Gina Demasellis

“…The median number of rescue sedative boluses, morphine equivalents (MEs), and benzodiazepine equivalents (BZDE) significantly decreased 2 days after the first phenobarbital dose compared to the 2 days before the first phenobarbital dose. …”
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Effect of Vitamin B12 supplementation in late-life depression: A randomized controlled trial by Pooja Misal, Shrikant Srivastava, Akanksha Sonal, Vivek Agarwal, Wahid Ali

“…Background: Late-life depression (LLD) has a poor response to the first-line standard antidepressant medications. This study aims to determine the effect of Vitamin B12 supplementation as an augmentation to the antidepressant medications as the first-line therapy in LLD to accelerate and/or maximize the response and remission. …”
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Nitric Oxide Concentration and Other Salivary Changes after Insertion of New Complete Dentures in Edentulous Subjects by Maria de Lourdes Breseghelo, Lídia Andreu Guillo, Túlio Eduardo Nogueira, Cláudio Rodrigues Leles

“…Pairwise comparison showed a reduction in NO concentration at the first follow-up compared to baseline values but differences were not statistically significant. …”
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Multi-center, prospective, non-interventional, observational study on the efficacy and safety of Mirabek® in adult patients with overactive bladder by Jee Soo Park, Won Sik Jang, Jongchan Kim, Moon-Hwa Park, Won Sik Ham

“…"Purpose: Mirabegron, the first-in-class beta-3 agonist, is the mainstay medication for overactive bladder (OAB). …”
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Monitoring of milk rennet coagulation: Chemical and physical perspective using Raman spectroscopy by Leonardo Sibono, Stefania Tronci, Martin Aage Barsøe Hedegaard, Massimiliano Errico, Massimiliano Grosso

“…Rheological cutting time was modelled using the time at the inflection point of first principal component scores, from which an R2 of 0.901 was obtained for calibration purposes, while 0.872 resulted from a 6-fold cross-validation. …”
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Anticoagulant management of cancer-associated thrombosis and thrombocytopenia: a retrospective chart review by Umaima Abbas, Robin MacKenzie, Ushra Khan, Rija Fatima, Tzu-Fei Wang, Rong Luo, Caroline Hamm, Andrea Cervi

“…Among patients treated with DOACs, there were no recurrent VTEs, 2 clinically relevant nonmajor bleeding events (12.5%) within the first 2 weeks, and 1 minor bleed (6.3%) in the second month, while those treated with LMWH had 1 recurrent VTE (5.3%) in the second month and 2 clinically relevant nonmajor bleeding events (10.5%) within the first 2 months. …”
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Clinical characteristics of EGFR-ctDNA shedders in EGFR-mutant NSCLC patients by Martina Ruglioni, Iacopo Petrini, Stefania Crucitta, Andrea Sbrana, Giovanna Irene Luculli, Leila Sadeghi Gol, Carola Forte, Antonio Chella, Christian Rolfo, Romano Danesi, Marzia Del Re

“…EGFR was assessed on tissue by standard procedures, while EGFR status on ctDNA was tested using dPCR at baseline and at the first reassessment. NGS was used to evaluate patients mutational status at the progression of the disease. …”
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Share on vk Share on google_plusone_share Share on twitter Share on email More Sharing Services Changes in the structure of the fungal soil community induced by contamination with... by L.R. Biktasheva, S.Y. Selivanovskaya, P.Y. Galitskaya

“…With the help of the Illumina MiSeq high-throughput sequencing, it was revealed that the fungal communities of the oil-contaminated samples S and C were least resistant to the oil contamination (the first changes were registered on the third day of incubation) as compared to sample D that suffered the first structural changes on the 30th day of the experiment. …”
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Identification and prioritization of effective approaches for public education and participation in household waste management (A case study: Tehran, Iran) by Esmatossadat Hashemi, Hooman Bahmanpour, Amir Hesam Hassani, Amir Hooman Hemmasi

“… This study aimed to identify and prioritize effective methods to increase public education and participation in household waste management in Tehran (capital of Iran) as a pilot city. First, baseline data were gathered through a library research process, and then 33 waste management experts were employed as a panel to complete a researcher-made questionnaire on a Likert scale. …”
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Surgical Treatment Patterns, Healthcare Resource Utilization, and Economic Burden in Patients with Tenosynovial Giant Cell Tumor Who Underwent Joint Surgery in the United States by Feng Lin, Winghan J. Kwong, Sherry Shi, Irina Pivneva, Eric Q. Wu, John A. Abraham

“…Opioids and nonsteroidal anti-inflammatory drugs (NSAIDs), and physical therapy, occupational therapy, and rehabilitation services, were commonly used during baseline (45%, 40%, and 30%, respectively). More patients used opioids in year 1 vs baseline (78% vs 45%; _P_<0.0001), while its utilization return to baseline levels in year 2 (41%) and year 3 (42%). …”
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Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments by Ning Ning, Sunandana Chandra, Andriy Moshyk, Divya Patel, Isabella C Glitza Oliva, Jennell Palaia, Leon A Sakkal, Natalia Han, Shardul Odak, Jordana K Schmier

“…However, the observed benefit may have been due to confounding and selection bias, given that patients receiving nivolumab plus ipilimumab had favourable baseline prognostic factors compared with patients receiving anti-PD-1 monotherapy or BRAF/MEK inhibitors.…”
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