The Use of Opioids and Pain Medications in the Management of Postoperative Pain in Total Knee Arthroplasty Patients: A Retrospective Study by Ammar Almustafa, Asdghig Der-Boghossian, Abdel Majid Sheikh Taha

“…For our 78 patients, there was no statistical difference for stratification by baseline characteristics except in spinal anesthesia, which decreased pain on the first day. …”
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Association between neutrophil-albumin ratio and ultrasound-defined metabolic dysfunction-associated fatty liver disease in U.S. adults: evidence from NHANES 2017–2018 by Ming-yu He, Xin-jie Du, Yi-ming Liu

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Programmed cell death 1 inhibitor alone or combined with chemotherapy for patients with locally advanced or metastatic urothelial carcinoma: a single-center experience by Xing Huang, Chupeng Sun, Peng Zhang, Lei Wang

“…A Cox regression analysis was conducted to explore the association of baseline variables with OS. Results In our cohort of 35 patients, 7 patients were treated with PD-1 inhibitor alone and 28 with PD-1 inhibitor plus platinum-based chemotherapy. …”
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The obesity paradox in osteoporosis risk among older adults is mostly driven by women: a population-based prospective study by Qingfeng Luo, Shiyong Zhang, Zixin Liang, Danni Wang, Yanlin Zhong, Bin Xia, Peng Xie, Can Wang, Jinqiu Yuan, Ziji Zhang, Xingsheng Li

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Correlation between Hyperalgesia and Upregulation of TNF-α and IL-1β in Aqueous Humor and Blood in Second Eye Phacoemulsification: Clinical and Experimental Investigation by Ruibo Yang, Chang Liu, Di Yu, Lechong Ma, Yan Zhang, Shaozhen Zhao

“…Corneal sensitivity (F =244.910, P <0.05), TNF-α and IL-1β levels in AH (F =184.200, 82.900, P <0.05) of non-surgical eyes and in whole blood (F =272.800, 193.530, P <0.05) in the experimental group were significantly higher than the baseline levels after phacoemulsification. In the clinical study, NRS scores of second eye surgery were higher than those of the first eye(P =0.0025) and 19 (63.3%) patients reported more pain during the second eye surgery. …”
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A single flow detection enabled method for DDoS attacks in IoT based on traffic feature reconstruction and mapping by Lixia XIE, Bingdi YUAN, Hongyu YANG, Ze HU, Xiang CHENG, Liang ZHANG

“…To address the slow response time of existing detection modules to Internet of things (IoT) distributed denial of service (DDoS) attacks, their low feature differentiation, and poor detection performance, a single flow detection enabled method based on traffic feature reconstruction and mapping (SFDTFRM) was proposed.Firstly, SFDTFRM employed a queue to store previously arrived flow based on the first in, first out rule.Secondly, to address the issue of similarity between normal communication traffic of IoT devices and DDoS attack traffic, a multidimensional reconstruction neural network model more lightweight compared to the baseline model and a function mapping method were proposed.The modified model loss function was utilized to reconstruct the quantitative feature matrix of the queue according to the corresponding index, and transformed into a mapping feature matrix through the function mapping method, enhancing the differences between different types of traffic, including normal communication traffic of IoT devices and DDoS attack traffic.Finally, the frequency information was extracted using a text convolutional network and information entropy calculation and the machine learning classifier was employed for DDoS attack traffic detection.The experimental results on two benchmark datasets show that SFDTFRM can effectively detect different DDoS attacks, and the average metrics value of SFDTFRM is a maximum of 12.01% higher than other existing methods.…”
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Solifenacin in Multiple Sclerosis Patients with Overactive Bladder: A Prospective Study by Farida van Rey, John Heesakkers

“…Thirty MS patients suffering from OAB were treated with solifenacin 5/10 mg for 8 weeks. The first 4 weeks patients received solifenacin 5 mg. …”
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User Outcomes for an App-Delivered Hypnosis Intervention for Menopausal Hot Flashes: Retrospective Analysis by Katherine Scheffrahn, Claire Hall, Vanessa Muñiz, Gary Elkins

“…The participants in the first group (daytime hot flashes and night sweats) were 139 women with ≥3 daily hot flashes who downloaded the Evia app between November 6, 2021, and June 9, 2022, with a baseline mean of 8.330 (SD 3.977) daily hot flashes. …”
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A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors by Mingchuan Zhao, Xichun Hu, Pengpeng Zhuang, Aiping Zeng, Yan Yu, Zhendong Chen, Hongmei Sun, Weihua Yang, Lili Sheng, Peijian Peng, Jingfen Wang, Tienan Yi, Minghong Bi, Huaqiu Shi, Mingli Ni, Xiumei Dai, Changlu Hu, Hongjie Xu, Dongqing Lv, Qingshan Li, Kaijian Lei, Xia Yuan, Ou Jiang, Xicheng Wang, Baihui Hu, Zhe Hou, Zhaoping Su, Song Zheng, Ming Zhou, Changlin Dou

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Downregulation of serum miR-30c-5p serves as a biomarker to predict disease onset and short-term prognosis in acute coronary syndrome patients by Bo Chang, Xiangfeng Zhang, Riliang Fang, Huibin Li, Youdan Zhou, Yakun Wang

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Efficacy of Topical Hydrocortisone in Combination with Topical Ciclosporin A for the Treatment of Dry Eye Disease in Patients with Sjögren Syndrome by Klemens Fondi, Kata Miháltz, Pia Veronika Vécsei-Marlovits

“…After 6 months of treatment, significant increases of tear BUT and corneal Fluorescein Oxford staining grade compared to baseline could be observed in both treatment groups. …”
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The Effects of Catheter Ablation Therapy on Medication Use and Expenditures in Patients with Atrial Fibrillation by Matthew R. Reynolds, Guy David, Candace Gunnarsson, Jamie L. March, Steven C. Hao

“…Propensity matching was used to account for baseline differences between groups, and multivariable regression models adjusted for patient characteristics and baseline healthcare resource utilization. …”
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Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 by Henry Chen, Henry Chen, Adam L. Numis, Adam L. Numis, Renée A. Shellhaas, John R. Mytinger, Debopam Samanta, Rani K. Singh, Rani K. Singh, Shaun A. Hussain, Danielle Takacs, Kelly G. Knupp, Li-Rong Shao, Carl E. Stafstrom

“…BackgroundInfantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin. …”
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Role of Huangqin Qingre Chubi Capsule in the Reduction of the Risk of Re-Admission in Patients With Ankylosing Spondylitis: A Cohort Study by Qi Y, Liu J, Chen Y, Hu Y, Zhou Q, Huang D, Cong C, Li Y

“…Patients were allocated into HQC and non-HQC groups. Baseline data between the two groups were matched with propensity score matching (PSM). …”
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Timing of Acupuncture during LTP-Like Plasticity Induced by Paired-Associative Stimulation by Xiao-kuo He, Qian-qian Sun, Hui-hua Liu, Xin-yi Guo, Cheng Chen, Li-dian Chen

“…The present examination is the first to report the influence of acupuncture on the motor-evoked potential (MEP) throughout the treatment process, including baseline (before acupuncture), the needle in situ, and the needle removal. …”
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Comprehensive Cervical Cancer Prevention in Tanzania (CONCEPT) study: Cohort profile by Ditte Søndergaard Linde, Vibeke Rasch, Julius D Mwaiselage, Rachel Manongi, Patricia Swai, Chunsen Wu, Bariki Mchome, Johnson Katanga, Crispin Kahesa, Susanne Kjaer

“…Data were collected at baseline, at 14 months (first follow-up) and at 28 months (second follow-up). …”
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Supraorbital Nerve Radiofrequency for Severe Neuralgia Caused by Herpes Zoster Ophthalmicus by Huan Zhang, Huadong Ni, Songlei Liu, Keyue Xie

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Mobile-based in-home telerehabilitation compared with in-hospital face-to-face rehabilitation for elderly patients after total hip arthroplasty in China's level 1 trauma center: a... by Yang Zhou, Yiming Lyu, Qiaojie Wang, Yanhong Ma, Lihua Huang, Xin Zhang, Xin Zhang

“…At 12 weeks follow-up evaluation, the main differences between the two groups regarding the HOOS gains, adjusted for baseline values, were close to zero (P &gt; 0.05). …”
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Effectiveness of Spinal Stabilization Exercises on Dynamic Balance in Adults with Chronic Low Back Pain by Yousef M. Alshehre, Khalid Alkhathami, Kelli Brizzolara, Mark Weber, Sharon Wang-Price

“…However, there were no significant between-group differences from baseline to two weeks (*p* =0.098), and from four weeks to eight weeks (*p* = 0.413)…”
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Prospective Study on Retinal Nerve Fibre Layer Thickness Changes in Isolated Unilateral Retrobulbar Optic Neuritis by Gordon S. K. Yau, Jacky W. Y. Lee, Patrick P. K. Lau, Victor T. Y. Tam, Winnie W. Y. Wong, Can Y. F. Yuen

“…This prospective cohort study recruited consecutive patients with a first episode of isolated, unilateral acute optic neuritis. …”
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