Effects of Metformin Added to Insulin in Adolescents with Type 1 Diabetes: An Exploratory Crossover Randomized Trial by Daizhi Yang, Jinhua Yan, Hongrong Deng, Xubin Yang, Sihui Luo, Xueying Zheng, Jing Lv, Wen Liang, Mengjie Hong, Zekai Wu, Bin Yao, Jianping Weng, Wen Xu

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Effectiveness of the Chronic Care Model in Type 2 Diabetes Management in a Community Health Service Center in China: A Group Randomized Experimental Study by Jing-Xia Kong, Lin Zhu, Hong-Mei Wang, Ying Li, An-Ying Guo, Chao Gao, Yan-Yao Miao, Ting Wang, Xiao-Yang Lu, Hong-Hong Zhu, Donald L. Patrick

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Elexacaftor/tezacaftor/ivacaftor and inflammation in children and adolescents with cystic fibrosis: a retrospective dual-center cohort study by Angela Pepe, Cristina Fevola, Daniela Dolce, Silvia Campana, Novella Ravenni, Giovanni Taccetti, Donatello Salvatore, Vito Terlizzi

“…Data on immunoglobulins (Ig) (A, G, and M), γ-globulin, leukocyte levels, percent predicted forced expiratory volume in the first second (ppFEV1), sweat chloride (SC) concentration, and sputum cultures were collected at baseline, 12, and 24 months of treatment. …”
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Characteristics and real-world medication persistence of people living with HIV treated with DTG/3TC or BIC/FTC/TAF: a hospital claims database study in Japan by Rie Kanamori, Nozomi Aoki, Akio Kanazawa, Mayumi Yuda, Nao Makino, Emi Ohata, Nobuyuki Fukui, Hirotake Mori, Hirohide Yokokawa, Toshio Naito

“…The proportion of dyslipidemia at baseline was significantly higher in the DTG/3TC cohort than in the BIC/FTC/TAF cohort after adjusting for mean age (p = 0.002). …”
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Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-naï... by David J Diemert, Maria Zumer, Mark Bova, Christina Gibbs-Tewary, Elissa M Malkin, Doreen Campbell, Lara Hoeweler, Guangzhao Li, Maria Elena Bottazzi, Peter J Hotez, Jeffrey M Bethony

“…In each cohort of 12 participants, 4 were randomized to receive 100 µg of Na-GST-1/Alhydrogel and 8 to receive 30 µg or 100 µg of Na-GST-1/Alhydrogel plus the Cytosine-phospho-Guanine (CpG) oligodeoxynucleotide Toll-like receptor-9 agonist, CpG 10104, in the first and second cohorts, respectively. Progression to the second cohort was dependent upon evaluation of 7-day safety data after all participants in the first cohort had received the first dose of vaccine. …”
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Enhancing Health Equity and Patient Engagement in Diabetes Care: Technology-Aided Continuous Glucose Monitoring Pilot Implementation Project by Madhur Thakur, Eric W Maurer, Kim Ngan Tran, Anthony Tholkes, Sripriya Rajamani, Roli Dwivedi

“…Their clinical characteristics included an average BMI of 29.91 kg/m2 and a mean baseline HbA1c level of 9.73%. Results indicate that the CGM program reduced HbA1c levels significantly from baseline to first follow-up (P<.001) and second follow-up (P<.001), but no significant difference between the first and second follow-up (P=.94). …”
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Effects of Urea Removal on the Stable Isotopes δ13C and δ15N in Rays from the Coastal Waters of Peninsular Malaysia by Maizah Mohd Abdullah, Wei Yien Lua, Roslanzairi Mostapha, Zalina Bashir, Mohd Naimullah, Sukree Hajisamae, Fazrul Hisam

“…Highlight Research • This is the first stable isotopes study of rays from Malaysian waters • Urea extraction significantly enriched the δ15N values ("°) • Urea removal is obliged for stable isotope studies on rays • Such methodological information is critical for marine research in the region   Abstract This is the first reported record of stable isotope values for elasmobranch rays within Malaysian waters, and serves as an important baseline methodological information for future studies investigating stable isotope values in both shark and ray species in the region. …”
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Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS... by Ramakanth Kavuluru, Xuan Wang, Paul Avillach, Florence Bourgeois, Kee Yuan Ngiam, Gabriel A Brat, Isaac Kohane, Tianxi Cai, Yuk-Lam Ho, Yuan Luo, Harrison G Zhang, Kelly Cho, Vincent Benoit, Antoine Neuraz, Chuan Hong, Sehi L'Yi, Griffin Weber, Bryce W Q Tan, Alba Gutiérrez-Sacristán, Clara-Lea Bonzel, Nathan P Palmer, Alberto Malovini, Valentina Tibollo, Meghan R Hutch, Molei Liu, Riccardo Bellazzi, Luca Chiovato, Fernando J Sanz Vidorreta, Trang T Le, William Yuan, Bertrand Moal, Michele Morris, David A Hanauer, Sarah Maidlow, Kavishwar Wagholikar, Shawn Murphy, Hossein Estiri, Adeline Makoudjou, Patric Tippmann, Jeffery Klann, Robert W Follett, Nils Gehlenborg, Gilbert S Omenn, Zongqi Xia, Arianna Dagliati, Shyam Visweswaran, Lav P Patel, Danielle L Mowery, Emily R Schriver, Malarkodi Jebathilagam Samayamuthu, Sara Lozano-Zahonero, Daniela Zöller, Amelia L M Tan, Byorn W L Tan, John H Holmes, Petra Schubert, Brett K. Beaulieu-Jones, Miguel Pedrera-Jiménez, Noelia García-Barrio, Pablo Serrano-Balazote, Andrew South

“…The laboratory recovery rates and mortality rates over time were compared between the two waves of the pandemic.Primary and secondary outcome measures The primary outcome was all-cause mortality rate within 28 days after hospitalisation stratified by predicted low, medium and high mortality risk at baseline. The secondary outcome was the average rate of change in laboratory values during the first week of hospitalisation.Results Baseline Charlson Comorbidity Index and laboratory values at admission were not significantly different between the first and second waves. …”
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Investigating the relationship between thought interference, somatic passivity and outcomes in patients with psychosis: a natural language processing approach using a clinical reco... by Robert Stewart, Anna Kolliakou, Jyoti Sanyal, Rashmi Patel, Thibault Thierry Magrangeas

“…Objectives We aimed to apply natural language processing algorithms in routine healthcare records to identify reported somatic passivity (external control of sensations, actions and impulses) and thought interference symptoms (thought broadcasting, insertion, withdrawal), first-rank symptoms traditionally central to diagnosing schizophrenia, and determine associations with prognosis by analysing routine outcomes.Design Four algorithms were developed on deidentified mental healthcare data and applied to ascertain recorded symptoms over the 3 months following first presentation to a mental healthcare provider in a cohort of patients with a primary schizophreniform disorder (ICD-10 F20-F29) diagnosis.Setting and participants From the electronic health records of a large secondary mental healthcare provider in south London, 9323 patients were ascertained from 2007 to the data extraction date (25 February 2020).Outcomes The primary binary dependent variable for logistic regression analyses was any negative outcome (Mental Health Act section, &gt;2 antipsychotics prescribed, &gt;22 days spent in crisis care) over the subsequent 2 years.Results Final adjusted models indicated significant associations of this composite outcome with baseline somatic passivity (prevalence 4.9%; adjusted OR 1.61, 95% CI 1.37 to 1.88), thought insertion (10.7%; 1.24, 95% CI 1.15 to 1.55) and thought withdrawal (4.9%; 1.36, 95% CI 1.10 to 1.69), but not independently with thought broadcast (10.3%; 1.05, 95% CI 0.91 to 1.22).Conclusions Symptoms traditionally central to the diagnosis of schizophrenia, but under-represented in current diagnostic frameworks, were thus identified as important predictors of short-term to medium-term prognosis in schizophreniform disorders.…”
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Investigating the Efficacy of an Individualized Alpha/Delta Neurofeedback Protocol in the Treatment of Chronic Tinnitus by Dominik Güntensperger, Christian Thüring, Tobias Kleinjung, Patrick Neff, Martin Meyer

“…First attempts have demonstrated that the application of alpha/delta neurofeedback in the treatment of chronic tinnitus leads to a reduction of symptoms at the group level. …”
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Impact of prolonged one or more natural menstrual cycles on the outcomes of ovulation induction intrauterine artificial insemination pregnancy: a single-centre, retrospective study... by Shuai Zhang, Han-Han Tang, Ming-Lian Zhou

“…Study participants were assigned into continuous and discontinuous groups. Differences in baseline clinical pregnancy and abortion rates were compared between the groups. …”
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Randomised control trial to compare the efficacy of traditional Thai massage and ultrasound therapy for treating plantar heel pain by Supamas Somphai, Wiraphong Sucharit, Punnee Peungsuwan, Neil Roberts, Uraiwan Chatchawan

“…Trial registration TCTR20210909001 (First Submitted Date: September 2021).…”
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The Impact of Step Recommendations on Body Composition and Physical Activity Patterns in College Freshman Women: A Randomized Trial by Bruce W. Bailey, Ciera L. Bartholomew, Caleb Summerhays, Landon Deru, Sharla Compton, Larry A Tucker, James D. LeCheminant, Joseph Hicks

“…Body weight and body composition were assessed at baseline and 24 weeks. Body composition was assessed by dual X-ray absorptiometry. …”
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Repeatability, reproducibility, and the effects of radiotherapy on radiomic features of lowfield MR-LINAC images of the prostate by Parker Anderson, Nesrin Dogan, John Chetley Ford, Kyle Padgett, Garrett Simpson, Radka Stoyanova, Matthew Charles Abramowitz, Alan Dal Pra, Rodrigo Delgadillo

“…This work investigated baseline repeatability of radiomic features (RFs) by comparing planning MR images (pMR) with first-fraction setup images (FX1) taken with onboard MRI. …”
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Study protocol for a hybrid implementation-effectiveness trial of Game Changers for Cervical Cancer Prevention in Uganda. by Glenn J Wagner, Laura M Bogart, Joseph K B Matovu, Violet Gwokyalya, Jolly Beyeza-Kashesya, Allison Ober, Harold D Green, Sylvia Nakami, Margrethe Juncker, Eve Namisango, Emmanuel Luyirika, Ryan K McBain, Kathryn Bouskill, Rhoda K Wanyenze

“…<h4>Discussion</h4>This is one of the first studies to use a network-driven approach and empowerment of CC screened peers as change agents to increase CC screening. …”
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A Review of Organic Photovoltaic Energy Source and Its Technological Designs by Egidius Rutatizibwa Rwenyagila

“…This is followed by the description of baseline organic solar cell (OSC) structures and materials. …”
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Real-World Long-Term Experience on Endoxifen in Bipolar Disorder with Psychotic Symptoms by Vikas Thanvi

“…This report presents a severe case of a BPAD patient with a baseline Young Mania Rating Scale (YMRS) score of 49, associated family history and addiction to psychostimulants, with no improvement by the first and second-generation antipsychotics. …”
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Whitefringed Beetles, Naupactus (= Graphognathus) spp. (Insecta: Coleoptera: Curculionidae) by Wayne N. Dixon

“… Naupactus leucoloma Boheman, the whitefringed beetle, was first collected in North America near Svea, Florida in 1936 (Buchanan 1939). …”
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Whitefringed Beetles, Naupactus (= Graphognathus) spp. (Insecta: Coleoptera: Curculionidae) by Wayne N. Dixon

“… Naupactus leucoloma Boheman, the whitefringed beetle, was first collected in North America near Svea, Florida in 1936 (Buchanan 1939). …”
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A distributed expectation maximization-principal component analysis monitoring scheme for the large-scale industrial process with incomplete information by Xuanyue Wang, Xu Yang, Jian Huang, Xianzhong Chen

“…Case studies on the Tennessee Eastman process is applied to show the effectiveness and performance of our proposed approach.…”
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