Oxygenation improvement and duration of prone positioning are associated with ICU mortality in mechanically ventilated COVID-19 patients by Silvia De Rosa, Nicolò Sella, Giacomo Bellani, Giuseppe Foti, Andrea Cortegiani, Giulia Lorenzoni, Dario Gregori, Annalisa Boscolo, Lucia Cattin, Muhammed Elhadi, Giorgio Fullin, Eugenio Garofalo, Leonardo Gottin, Alberto Grassetto, Salvatore Maurizio Maggiore, Elena Momesso, Mario Peta, Daniele Poole, Roberto Rona, Ivo Tiberio, Andrea Zanoletti, Emanuele Rezoagli, Paolo Navalesi, for the SIAARTI Study Group

“…We measured the difference for arterial partial pressure of oxygen to inspired fraction of oxygen ratio (PaO2/FiO2), ventilatory ratio, and respiratory system compliance (Crs) between baseline supine position and at either the end of the first cycle of prone position (Delta-PP) or re-supination (Delta-PostPP). …”
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The Relationship Between LRP-5 and LRP-6 Gene Mutations and Postmenopausal Type 2 Diabetes and Obesity by Jun Li, Ya Li, Yunqiu Lu, Siyuan Li, Yecheng Zhu, Chuanbing Sun, Partab Rai, Xuehai Jia

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Jinbei oral liquid for idiopathic pulmonary fibrosis: a randomized placebo-controlled trial by Aijun Zhang, Kangkang Han, Fangfang Chen, Xiao Chen, Jun Wang, Yikai Niu, Zhaoqiu Hu, Chunyan Zheng, Liping Han, Zhaoqing Meng, Liangzong Zhang, Qingcui Xu, Cuixiang Yu, Wei Zhang, Quanguo Li, Ningning Tao, Weixiang Kong, Fei Liu, Min Wang, Juanjuan Jiang, Honglin Li, LongBin Pang, Huaichen Li

“…To assess efficacy, over the duration of the trial, we measured serial changes in a composite indicator encompassing time to first acute exacerbation of IPF (first hospitalization or death due to respiratory cause), total lung capacity (TLC) (mL), predicted forced vital capacity (FVC%), forced vital capacity (FVC) (mL), predicted diffusing capacity of the lungs for carbon monoxide (predicted DLco%), 6-minute walk distance (6MWD), St. …”
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Prevalence and predictive factors of testosterone-induced erythrocytosis: a retrospective single center study by Anina Neidhart, Viktor von Wyl, Viktor von Wyl, Benno Käslin, Christoph Henzen, Stefan Fischli

“…There was an association between the baseline HCT measurement and the outcome of a HCT measurement ≥0.46 (p=0.025), patients with high starting values were more likely to develop TIE.ConclusionsTIE appears to be frequent and does not only present within the first year of therapy which indicates a close follow-up of laboratory values within the first year followed by annual controls. …”
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Expression of Interferon Effector Gene SART1 Correlates with Interferon Treatment Response against Hepatitis B Infection by Yong Li, Chuanlong Zhu, Faxi Wang, Tiantian Zhu, Jun Li, Shufeng Liu, Fei Xiao

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The impact of short-term changes in sleeping and eating patterns on glucometabolic health and gut microbiota in healthy young adults: a proof-of-concept controlled feeding study by Jiehua Chen, Ruijie Zhang, Chao Zhou, Louise Weiwei Lu, Dana Feng, Haiqiao Zou, Ran Gao, Xinying Zhang, Peiyi Chen, Jiayue Zhu, Haoxie Xu, Nina Zeng, Cijuan Zhang, Bin Liu, Mingfu Wang, Qian Ge, Caiqun Ouyang, Feng Chen

“…Circadian rhythm misalignment led to significantly higher levels of fasting glucose and homeostatic model assessment for insulin resistance (HOMA-IR) of subjects compared to baseline and failed to recover to the baseline level in circadian rhythm realignments. …”
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A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint by Zhi-qiang Song, Chen‑xi Li, Zhong‑cheng Gong

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Effect of β-blocker on clinical outcomes in patients with traumatic brain injury: a retrospective propensity-matched study by Yaxin Zhang, Tingting Liu, Wenwen Ji, Guangdong Wang

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Effects of levothyroxine therapy on bone and mineral metabolism in hypothyroidism: a systematic review and meta-analysis by Xiaotao Li, Taotao Zhang, Hongling Zhang, Shanshan Liu, Limin Tian

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A Comparative Study of Two Anesthetic Agents Thiopentone Sodium and Propofol in Modified Electroconvulsive Therapy by Sanagapalli S. V. L. Manasa, E. Ananda Reddy, V. Harshitha, Velama Pooja Prasanna, Chennuru Kavya Lekha, Javangula Swetha Krishna

“…The mean BCRS scores were significantly different at the first post-MECT (p < 0.05) and the last post-MECT (p < 0.05) between two anesthetic groups. …”
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Treatment Patterns of Follicular Lymphoma in the United States: A Claims Analysis by Scott F. Huntington, Sreevalsa Appukkuttan, Wenyi Wang, Yuxian Du, Sari Hopson, Svetlana Babajanyan

“…Descriptive statistics were reported for baseline characteristics, primary outcome, and treatment pattern measures. …”
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Long-Term Effects of Adjuvant Intravitreal Treatment with Autologous Bone Marrow-Derived Lineage-Negative Cells in Retinitis Pigmentosa by Marta P. Wiącek, Wojciech Gosławski, Aleksandra Grabowicz, Anna Sobuś, Miłosz P. Kawa, Bartłomiej Baumert, Edyta Paczkowska, Sławomir Milczarek, Bogumiła Osękowska, Krzysztof Safranow, Alicja Zawiślak, Wojciech Lubiński, Bogusław Machaliński, Anna Machalińska

“…Patients whose symptoms started less than 10 years ago gained 14±10 letters, while those with a longer disease duration gained 2.86±8.54 letters compared to baseline at the 12-month follow-up (p=0.021). There were significantly higher differences in response densities of P1-wave amplitudes in the first ring of multifocal ERGs in treated eyes than FE recordings in all follow-up points were detected. …”
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Aerodynamic Optimization of a UAV Wing subject to Weight, Geometric, Root Bending Moment, and Performance Constraints by Durmuş Sinan Körpe, Öztürk Özdemir Kanat

“…Three different optimization problems are solved. In the first problem, the maximization of CL3/2/CD is the objective function, while level flight condition at maximum CL3/2/CD is defined as a constraint. …”
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Exploring the clinical significance of anti-acetylcholine receptor antibody titers, changes, and change rates in Myasthenia Gravis by Lijun Luo, Xinyi Zhu, Chunbei Wen, Yifan Guo, Jie Yang, Dongsheng Wei, Ping Yu, Mei Wan

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Efficacy and safety of sequential therapy for primary osteoporosis with bone formation promoters followed by bone resorption inhibitors: a meta-analysis by Yuxin Liu, Xin Liu, Yuefeng Wu, Tao Luo

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Knowledge Enhancement of Elementary School Staff about Traumatic Dental Injuries Using Different Educational Tools by Mojtaba Salehi Karizmeh, Fatemeh Mozaffari, Monirsadat Mirzadeh, Razieh Jabbarian

“…A significant correlation was noted between the baseline knowledge level of the participants and their educational level, participation in first aid courses covering TDIs, and history of encountering TDIs (P<0.05). …”
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Population pharmacokinetics of iruplinalkib in healthy volunteers and patients with solid tumors by Guihong Yang, Yimei Wang, Huimin Zhao, Ziyi Jiang, Shansong Zheng, Mingjing Ge, Meimei Si, Xiaoyan Kang

“…Iruplinalkib plasma concentrations were best described by a two‐compartment model with first‐order absorption and first‐order elimination. …”
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Collagen turnover biomarkers to predict outcome of patients with biliary cancer by Leonard Kaps, Muhammed A. Genc, Markus Moehler, Stephan Grabbe, Jörn M. Schattenberg, Detlef Schuppan, Rasmus Sund Pedersen, Morten A. Karsdal, Philipp Mildenberger, Annett Maderer, Nicholas Willumsen

“…Methods We measured the seven biomarkers of collagen turnover in sera of 72 patients with BTC at baseline and after first and second chemotherapy cycle (CTX). …”
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Exploring early Acheulian technological decision-making: A controlled experimental approach to raw material selection for percussive artifacts in Melka Wakena, Ethiopia. by Eduardo Paixão, Tegenu Gossa, Walter Gneisinger, João Marreiros, Sören Tholen, Ivan Calandra, Erella Hovers

“…We present the results of the first experimental step, in which we identified and measured the engineering properties of raw materials in the lithic assemblages. …”
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Modified autologous neurosensory retinal transplantation and bevacizumab injection in primary extra-large chronic macular holes by Hossein Ashraf, Sezaneh Haghpanah, Mohammad Hossein Nowroozzadeh

“…The median LogMAR BCDVA at baseline was 1.4 (1.3–1.4) which decreased to 1.1(1.0–1.1) (P = 0.041) at the first month and 1.0 (0.7–1.2) (P = 0.043) at the last follow-up. …”
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