Granulomatous lymphocytic interstitial lung disease in common variable immune deficiency: an in-depth clinical, immunological, functional and radiological exploration with a focus... by Mattia Moratti, Mattia Moratti, Gioacchino Schifino, Francesco Baccelli, Francesco Baccelli, Simona Ferrari, Elisabetta Magrini, Mirna Bassi, Aldo Guerrieri, Maurizio Zompatori, Marcello Lanari, Marcello Lanari, Francesca Conti, Francesca Conti

“…CMV infection in patients with GLILD on immunosuppressants resulted in favorable outcomes, underscoring the importance of personalized treatment strategies.ImplicationsThis study highlights novel immunological markers and clinical-radiological patterns as potential predictors for GLILD, advocating for their integration into diagnostic and monitoring frameworks to reduce reliance on invasive histopathology. …”
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Dementia Scale Score Classification Based on Daily Activities Using Multiple Sensors by Akira Minamisawa, Shogo Okada, Ken Inoue, Mami Noguchi

“…We analyzed the effects of different types of sensor data, such as time spent in an individual room according to human motion sensors, location in a facility, and sleep patterns, on dementia detection. We then developed a feature extraction method related to daily activity patterns based on a clustering algorithm and analyzed its effectiveness. …”
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A next-generation system for smoke inhalation integrated with a breathing lung-on-chip to model human lung responses to cigarette exposure by Arunima Sengupta, Saskia Schmid, Noémie Grangier, Aurélien Dorn, Marco Hebestreit, Andreas Hugi, Kristína Žajdlíková, Anja Herbst, Paula Losada-Oliva, Heidi Ortolf-Wahl, Philippe Krebs, Janick D. Stucki, Vera van der Velpen, Jesus Perez-Gil, Tobias Krebs, Nina Hobi, Olivier T. Guenat

“…Abstract Continuous exposure to cigarette smoke (CS) significantly contributes to the development and progression of chronic obstructive pulmonary disease (COPD) and lung cancer. …”
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Study on the prehistoric decorated spindle whorls in Haidai region of China by Yuan Tao, Qicai Wang

“…The patterns on the decorated spindle whorls were analyzed and classified, and the characteristics of the patterns in different cultural periods were studied, and based on this, the purpose of making decorated spindle whorls and the function and meanings of the patterns were discussed. …”
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Editorial by Bulent Cavas

“…Dear Readers,It is with great pleasure that we present the June 2025 issue of Science Education International. This issue features 11 original research articles that highlight contemporary developments, challenges, and opportunities in science education. …”
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Hematological analysis as a method of monitoring physiological status of medium carnivorous mammals in the Russian Far East by Galina S. Alekseeva, Mariya N. Erofeeva, Jose A. Hernandez-Blanco, Mikhail N. Litvinov, Mariya D. Chistopolova, Mariya D. Kim, Viatcheslav V. Rozhnov, Sergey V. Naidenko

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Optimizing Monkeypox Lesions Detection With a Lightweight Hybrid Model by Mehdhar S. A. M. Al-Gaashani, Reem Ibrahim Alkanhel, Dina S. M. Hassan, Abduljabbar S. Ba Mahel, Ahmed Aziz, Mashael M. Khayyat, Ammar Muthanna

“…The increasing global prevalence of monkeypox (mpox) has necessitated the development of accurate, efficient, and interpretable diagnostic models for timely disease identification. …”
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An enhanced fusion of transfer learning models with optimization based clinical diagnosis of lung and colon cancer using biomedical imaging by N. A. S. Vinoth, J. Kalaivani, R. Madonna Arieth, S. Sivasakthiselvan, Gi-Cheon Park, Gyanendra Prasad Joshi, Woong Cho

“…Furthermore, fusion models such as CapsNet, EffcientNetV2, and MobileNet-V3 Large are employed for the feature extraction. The FTLMO-BILCCD technique implements a hybrid of temporal pattern attention and bidirectional gated recurrent unit (TPA-BiGRU) for classification. …”
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Identification of Cultural Landscapes and Spatial Distribution Characteristics in Traditional Villages of Three Gorges Reservoir Area by Jia Jiang, Zhiliang Yu, Ende Yang

“…Through field surveys, landscape feature assessments, GIS spatial analysis, and multi-source data analysis, we systematically analyse their cultural landscape type systems and spatial differentiation characteristics, and then reveal their cultural landscape types and spatial differentiation patterns. (1) The results of the study show that the spatial distribution of traditional villages exhibits significant altitude gradient differentiation—the low-altitude area is dominated by traffic and trade villages, the middle-altitude area is dominated by patriarchal manor villages and mountain farming villages, and the high-altitude area is dominated by ethno-cultural and ecologically dependent villages. (2) Slope and direction analyses further reveal that the gently sloping areas are conducive to the development of commercial and agricultural settlements, while the steeply sloping areas strengthen the function of ethnic and cultural defence. …”
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Multi-omics analysis identifies a liquid-liquid phase separation-related subtypes in head and neck squamous cell carcinoma by Peng-Lei Zhai, Peng-Lei Zhai, Meng-Min Chen, Meng-Min Chen, Meng-Min Chen, Qi Wang, Jing-Jun Zhao, Xiao-Mei Tang, Cui-Ni Lu, Jia Liu, Qin-Xin Yang, Ming-Liang Xiang, Qing-Hai Tang, Biao Gu, Shu-Ping Zhang, Si-Ping Tang, Da Fu, Da Fu

“…We confirmed notable differences among these subtypes in terms of prognosis, functional enrichment, genomic alterations, TIME patterns, and responses to immunotherapy. Additionally, we developed the LPRS, a prognostic signature for personalized integrative assessments, which demonstrated strong predictive capability for HNSCC prognosis across multiple cohorts. …”
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Improved chaotic fruit fly optimization with elman neural network based data-driven approach on product reviews classification by Mohammed Alghamdi, Najla I. Al-shathry, Yahia Said, Hasan Beyari, Shaymaa Sorour, Khalid Nazim Abdul Sattar, Fouad Shoie Alallah, Abdulrhman Alshareef

“…Yet, predicting the correct sentiment difference in customer feedback is challenging due to complicated logic, sequence length, and text pattern adjustments. This article focuses on designing and developing Enhanced NLP with Data-driven Product Reviews Classification using the improved chaotic fruit fly optimization (ENLPPR-ICFFO) method. …”
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The Microchimerism Literature Atlas by Michael Christian Gruber, Daniel Kummer, Katja Sallinger, Henderson James Cleaves, Arsev Umur Aydinoğlu, Thomas Kroneis

“…The MCLA is being developed as an essential resource for the MC research community while its framework is easily adaptable for custom literature datasets, enabling its use in other research fields.…”
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Psychotherapist remarks’ ML classifier: insights from LLM and topic modeling application by Alexander Vanin, Vadim Bolshev, Anastasia Panfilova

“…The resulting topics are used as features to train an ML classifier, which is then tested on a case study comparing Carl Rogers’ sessions with those of modern Cognitive Behavioral Therapy (CBT) practitioners.ResultsThe analysis identifies the most common and stable topics across both therapist groups, highlighting recurring patterns and unique thematic compositions. …”
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Dichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome by Jiao Sun, Jin-Young Kim, Semo Jun, Meeyeon Park, Ebbing de Jong, Jae-Woong Chang, Sze Cheng, Deliang Fan, Yue Chen, Timothy J. Griffin, Jung-Hee Lee, Ho Jin You, Wei Zhang, Jeongsik Yong

“…The application of this workflow to RNA-seq data from The Cancer Genome Atlas demonstrated that this dichotomous intronic APA pattern is a consistent feature in transcriptomes across both normal tissues and various cancer types. …”
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Vibration mitigation in interlocking metasurfaces by O. Bolmin, P.J. Noell, N. Leathe, B.L. Boyce

“…Interlocking metasurfaces (ILMs) are a new class of mechanical metamaterials with patterned surface features that enable joining of two adjacent bodies, serving as an alternative to welds, fasteners, or adhesives. …”
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Polygenic prediction of human longevity on the supposition of pervasive pleiotropy by M. Reza Jabalameli, Jhih-Rong Lin, Quanwei Zhang, Zhen Wang, Joydeep Mitra, Nha Nguyen, Tina Gao, Mark Khusidman, Sanish Sathyan, Gil Atzmon, Sofiya Milman, Jan Vijg, Nir Barzilai, Zhengdong D. Zhang

“…We showed that coefficients derived from our ensemble model could potentially reveal an interesting pattern of genomic pleiotropy specific to lifespan. …”
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Classification of Beef, Goat, and Pork using GLCM Texture-Based Backpropagation Neural Network by Irma Saraswati, Rian Fahrizal, Anugrah Nuur Fauzan, Muchtar Ali Setyo Yudono

“…This research makes a significant contribution to developing a meat identification system that safeguards consumers and promotes awareness of food safety issues. …”
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The Architectural Production of India’s Everyday Modernism: Middle-class Housing in Pune, (1960-1980) by Sarah Melsens, Inge Bertels, Amit Srivastava

“…The large-scale appropriation of modernist architectural features in everyday housing projects in postcolonial India is remarkable. …”
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A Comprehensive Analysis of Imbalance Signal Prediction in the Japanese Electricity Market Using Machine Learning Techniques by Kaiyao Jiang, Yuji Yamada

“…By incorporating a diverse range of features—including lagged imbalance data, weather forecast errors specific to Japan, and temporal patterns—we demonstrate that the prediction accuracy of imbalance signals is significantly improved compared to a baseline reflecting random forecasts based on class distribution observed during the initial training period. …”
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The use of artificial intelligence to analyze and optimize financial flows by М. А. Miakisheva

“…The article systematizes modern ideas about the features of using artificial intelligence tools in order to analyze and optimize financial flows. …”
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