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  1. 3061

    Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. by Shih Chieh Liang, Ben Hartwig, Pumi Perera, Santiago Mora-García, Erica de Leau, Harry Thornton, Flavia de Lima Alves, Juri Rappsilber, Suxin Yang, Geo Velikkakam James, Korbinian Schneeberger, E Jean Finnegan, Franziska Turck, Justin Goodrich

    Published 2015-12-01
    “…The antagonistic interaction of a modified transposase with the PcG machinery is novel and may have arisen as a means for the cognate transposon to evade host surveillance or for the host to exploit features of the transposition machinery beneficial for epigenetic regulation of gene activity.…”
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  2. 3062

    Nosological and Age and Gender Profile of the Vologda Oblast Population Mortality and the Associated Demographic Losses by A. V. Korolenko

    Published 2021-07-01
    “…At the same time, its features “slow down” the evolution of the mortality structure, such as a high proportion of young age groups (under 45 years old), especially categories 30-44 years old, in mortality from external causes, infectious and parasitic diseases, endocrine diseases, nutritional disorders, metabolic disorders and, as a result, the large scale of premature mortality of the region's population; male premature super-mortality, as well as the high contribution of the child population (0-14 years old) to premature mortality from diseases of the nervous system and sensory organs.Conclusion. …”
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  3. 3063
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  5. 3065

    Towards a learning healthcare community in the Bronx: evaluating the Bridging Research, Accurate Information and Dialogue (BRAID) model by Sarah M. McNeilly, Katherine W. Wang, Sarah A. Jacobs, Nang S. Yone, Debra A. Williams, Bruce D. Rapkin, Caroline Davis Joseph, Damara N. Gutnick

    Published 2025-02-01
    “…Abstract Background Learning healthcare communities (LHCCs) have been proposed as a next-generation evolution of learning health systems that can advance health equity; however, a practical mechanism for enabling the active and continuous community engagement required for one has not yet been described in the literature. …”
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  6. 3066

    Visibility Graph Investigation of the Shallow Seismicity of Lai Chau Area (Vietnam) by Luciano Telesca, Anh Tuan Thai, Dinh Trong Cao, Thanh Hai Dang

    Published 2024-10-01
    “…Analyzing the variation of the seismological and topological parameters of the seismicity relative to the distance from the center of the Lai Chau reservoir revealed the following features: (1) the <i>b</i>-value fluctuates around a mean value of 1.21 at distances of up to 10–11 km, while, for distances larger than 25–30 km, it tends to the value of 0.86; (2) the maximum IMI between the monthly number of earthquakes and the monthly mean water level occurs at a distance of 9–11 km, showing a distance evolution similar to that of the <i>b</i>-value; (3) at these distances from the center of the reservoir, the time lag between the earthquake monthly counts and the monthly water level mean is 9–10 months; (4) the relationship between the <i>b</i>-value and the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>k</mi><mo>−</mo><mi>M</mi></mrow></semantics></math></inline-formula> slope suggests that the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>k</mi><mo>−</mo><mi>M</mi></mrow></semantics></math></inline-formula> slope depends on the number of earthquakes within a 22 km radius from the center of the dam. …”
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  7. 3067

    Study on Secondary Remelting Modification of Laser Cladding Ni60/WC Composite Coatings by Jianwen Zhang, Gui Wang, Jingquan Wu, Jiang Huang, Wenqing Shi, Fenju An, Xianglin Wu

    Published 2025-05-01
    “…The results underscore the critical influence of laser scanning velocity and remelting frequency on microstructural evolution, mechanical strength, and electrochemical stability. …”
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  8. 3068

    Spatiotemporal patterns of accumulation and surface roughness in interior Greenland with a GNSS-IR network by D. J. Pickell, R. L. Hawley, A. LeWinter

    Published 2025-03-01
    “…For the first time, we also validate GNSS-IR sensitivity to meter-scale surface heterogeneities such as sastrugi, and we construct a time series of surface roughness evolution that suggests a seasonal pattern of heightened wintertime roughness features in this region. …”
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  9. 3069

    Mechanical properties and permeability characteristics of mudstone-slag-based water barrier material by Yu ZHANG, Yuanguang CHEN, Qibo PAN, Yafei ZHANG, Tian CHEN, Pengjiao ZHANG, Jiangsen ZHU

    Published 2025-06-01
    “…Based on the uniaxial compressive strength and permeability obtained from the test, we investigated the influence mechanism of mudstone content on the mechanical properties and permeability characteristics of mudstone-slag-based water barrier materials, analyzed the evolution law of the mechanical properties and permeability characteristics of mudstone-slag-based water barrier materials under different curing age conditions, and supplemented with scanning electron microscope tests, studied the characteristics and morphological features of different cementation products in mudstone-slag-based water barrier materials, and studied the influence of mudstone proportion on the macroscopic damage forms of mudstone-slag-based water barrier materials. …”
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  10. 3070

    Early Diabetic Retinopathy Detection from OCT Images Using Multifractal Analysis and Multi-Layer Perceptron Classification by Ahlem Aziz, Necmi Serkan Tezel, Seydi Kaçmaz, Youcef Attallah

    Published 2025-06-01
    “…Therefore, the development of reliable, non-invasive, and automated screening tools has become increasingly vital in modern ophthalmology. With the evolution of medical imaging technologies, Optical Coherence Tomography (OCT) has emerged as a valuable modality for capturing high-resolution cross-sectional images of retinal structures. …”
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  11. 3071
  12. 3072

    Microbial Ecology and Metabolism of Emerging Adulthood: Gut Microbiome Insights from a College Freshman Cohort by Alex E. Mohr, Paniz Jasbi, Irene van Woerden, Jinhua Chi, Haiwei Gu, Meg Bruening, Corrie M. Whisner

    Published 2024-12-01
    “…Despite improved understanding over the past years about how genetics, lifestyle, and the external environment impact the GM, limited research has explored the GM’s evolution during late-stage adolescence, especially among college students. …”
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  13. 3073
  14. 3074

    Geochemical and tectonic setting of mafic dyke swarms of the Juruena-Teles Pires mineral province, southwestern Amazonian craton, Brazil by Gilmar Rizzotto, Cléber Alves

    Published 2025-04-01
    “…The HTi and LTi dykes are tholeiitic and classified as continental flood basalts, displaying distinct geochemical features. LTi dykes have Mg# values ranging from 0.32 to 0.58 and are enriched in Ba, K, Rb, Sr, Ce, and Y, with low to moderate MgO, Ni, and Cr contents, and moderate LREE enrichment. …”
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  15. 3075

    Study on the Characteristics of Top-Coal Caving and Optimization of Recovery Ratio in Steeply Inclined Residual High Sectional Coal Pillar by Wenhua Yang, Xingping Lai, Pengfei Shan, Feng Cui, Yiran Yang

    Published 2020-01-01
    “…With the advancement of the working face, the top-coal arch structure was in the process of dynamic evolution, as the old arch balance system was continuously replaced by the new arch balance system, and it continuously moved towards the upper top coal. …”
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  16. 3076
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  18. 3078

    Unbiased High-Precision Cloud Detection for Advanced Himawari Imager Using Automatic Machine Learning by Bochun Liu, Jinming Ge, Qingyu Mu, Chi Zhang, Xiaoyu Hu, Jiajing Du, Yanyan Wu, Bo Wang, Xiang Li, Jianping Huang, Qiang Fu

    Published 2025-01-01
    “…Clouds play a pivotal role in the global radiation budget and energy cycle, making accurate cloud detection via satellite remote sensing essential for understanding their evolutions. However, existing machine learning-based cloud detection algorithms have limitations, particularly in data preprocessing and feature engineering, and few are designed to cover the entire geostationary satellite observation region. …”
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