LC-QTOF-MSE with MS1-based precursor ion quantification and SiMD-assisted identification enhances human urine metabolite analysis by Alongkorn Kurilung, Suphitcha Limjiasahapong, Kwanjeera Wanichthanarak, Weerawan Manokasemsan, Khwanta Kaewnarin, Kassaporn Duangkumpha, Siriphan Manocheewa, Rossarin Tansawat, Roongruedee Chaiteerakij, Intawat Nookaew, Yongyut Sirivatanauksorn, Sakda Khoomrung

“…This study presents the development and validation of a liquid chromatography–quadrupole-time-of-flight mass spectrometry method with data-independent acquisition (LC-QTOF-MSE) for targeted quantification, post-targeted screening, and untargeted metabolite profiling. …”
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Teaching coherent descriptive speech to children of senior preschool age with speech underdevelopment problems by L. G. Shadrina, O. V. Efimova

“…However, in modern speech therapy, the development of coherent speech is made dependent on the elimination of the shortcomings of unformed language structures and involves the use of reproductive techniques, including mainly constant repetitions of speech patterns. …”
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Intellectual elite and Homo intellectualis of the information civilization by Tamara L'vovna Salova

“…The emergence of a new class of intellectuals - the intellectual elite - is associated with the transition to an information civilization, which is considered by futurologists as the modern stage of human development, when intelligence becomes the central concept, and intellectual culture determines the level of intelligence development.The study of the role of the intellectual elite in the society and the description of the "portrait" of a representative of the intellectual elite is the purpose of the research.The methodological basis of the research is a dialectical logic, which gives an idea of the patterns of the development; a systematic approach associated with the idea of an object as an integral system, with the identification of diverse types of connections of a complex object and bringing them into a single theoretical picture.As a result of the research, the main purpose of the intellectual elite has been revealed, the features of intellectual labor in a society with a network structure of interaction determined, and the conclusion made that the intellectual elite is at the same time a spiritual and moral elite, i.e. represents the modern intelligentsia.The rationale for the introduction of the new concept of "Homo intellectualis" (intellectual person) into scientific circulation can be considered as a key conclusion.The relevance of the topic and its practical significance is connected with the strategic line of the state to raise the prestige of intellectual labor and increase the intellectual potential of the nation.…”
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Light focusing and additive manufacturing through highly scattering media using upconversion nanoparticles by Qianyi Zhang, Antoine Boniface, Virendra K. Parashar, Viola Sgarminato, Jorge Madrid-Wolff, Martin A. M. Gijs, Christophe Moser

“…The propagation of light is scrambled to form random speckle patterns, making it impossible to print features at the diffraction-limited size with conventional printing approaches. …”
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Land cover changes in grassland landscapes: combining enhanced Landsat data composition, LandTrendr, and machine learning classification in google earth engine with MLP-ANN scenari... by Cecilia Parracciani, Daniela Gigante, Onisimo Mutanga, Stefania Bonafoni, Marco Vizzari

“…However, the classification of shrublands proved challenging due to their mixed composition and unique spatial patterns, resulting in lower accuracies. Feature importance analysis demonstrated the value of the enhanced map composition, and applying the LandTrendr algorithm simplified the diachronic land use and land cover (LULC) classification and change analysis by supporting automatic training data collection. …”
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Reusable Respiratory and Skin Protective Devices Will Help Russian NBC Protection Troops to Avoid Pathogenic Biological Agents by Valerii V. Vasilyev, Sergei N. Solovykh, Nikita V. Danyakin., Pavel V. Gorbachev

“…Considering all that the enterprises started a large-scale production of efficient respiratory and skin protective devices for medical staff in Kostroma and other regions of the Russian Federation. Design features of garment with respiratory and skin protective devices have served as a pattern for a promising protective set for Russian NBC Protection Troops that will help them to avoid pathogenic biological agents.…”
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Complex immunohistochemical and molecular study on 5 cases of ovarian juvenile granulosa cell tumors reveals a consistent alteration in the PI3K/AKT/mTOR signaling pathway by Adam Šafanda, Nikola Hájková, Michaela Kendall Bártů, Marián Švajdler, Radoslav Matěj, Jitka Hausnerová, Tomáš Zima, Pavel Dundr, Kristýna Němejcová

“…Abstract Background Juvenile granulosa cell tumor (JGCT) of the ovary is a rare tumor with distinct clinicopathological and hormonal features primarily affecting young women and children. …”
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Kinship analyses in forensic genetics: when complex hypotheses meet (very) complex genotypes by Marisa Faustino, Leonor Gusmão, António Amorim, Daniel Kling, Nádia Pinto

“…In such cases, it might be useful to analyze the X chromosome due to its unique features, specifically its haplodiploid mode of transmission and recombination pattern, which have been proven to be powerful to complement the information given by the autosomes or to solve complex kinship cases [1]. …”
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Clinical manifestations, histopathological changes and quality of life in patients with advanced knee osteoarthritis caused by age, trauma, obesity and their combination by Kristina V. Korochina, Tatyana V. Chernysheva, Irina E. Korochina

“…The methodological basis for differential approach to treating different categories of OA patients was developed.…”
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Non-invasive detection of Parkinson’s disease based on speech analysis and interpretable machine learning by Huanqing Xu, Wei Xie, Mingzhen Pang, Ya Li, Luhua Jin, Fangliang Huang, Xian Shao

“…This study aims to develop an interpretable machine learning model that uses speech recordings and acoustic features to predict PD.MethodsA dataset of speech recordings from individuals with and without PD was analyzed. …”
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Generation and recognition of eye movement samples based on generative artificial intelligence by TAN Xueqing, SONG Jun, ZHANG Manman, ZANG Chuanli

“…Interpreting generative datasets based on grey relational analysis and confusion matrix.ResultsThe results showed that： （1）the eye movement datasets generated by VAE for 4， 5， and 6 years old children had higher accuracy than the MINIST dataset（mixed National Institute of Standards and Technology）， and were consistent with the MLP analysis results， with accuracy， diversity， and certain interpretability； （2）The results of generative eye movement data and confusion matrix indicated that in unfocused structure， children’s understanding level improved at the ages of 4~5 and 5~6， while the eye movement characteristics of object-focus structure and subject-focus structure changed less at the ages of 4~5 and more at the ages of 5~6， indicating that children’s understanding of focus structure was a critical period at the age of 5， which was in line with the development law of children’s understanding of focus structure.ConclusionsThe artificial intelligence coupling analysis proposed in this article could identify the development patterns of eye movement features and generate reliable new samples， providing new ideas for the combination of generative artificial intelligence and eye movement technology.…”
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Integration of biomimetic organoid-on-chip and 2D models advances the mechanistic Understanding of STEAP3-mediated regulation in intestinal viral infection by Yi-Wen Chen, Huan-Jung Chiang, Kuan-Ting Liu, Chun-Wei Kao, Shan-Ren Xie, Chao-Ming Su, Yu-Yin Shih

“…These systems often fail to capture key features such as spatial cell–cell interactions, tissue-specific heterogeneity, and microenvironmental complexity that govern virus–host dynamics in vivo. …”
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Dynamic token encryption for preventing permission leakage in serverless architectures by Yu Liu, Fu Li, Chenhao Sun

“…Moreover, the designed multi-factor token verification model integrates dynamic factors such as call chain features and behavior patterns, which can defend against various security threats. …”
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Sedimentary characteristics and influencing factors of steep slope platform-margin reefs: A case study of Changxing Formation in Kaijiang-Liangping Trough in northeastern Sichuan B... by HUANG Yuxuan, CHEN Xu, WU Saijun, WEI Junhong, WANG Jingyuan

“…Gentle and steep slope platform-margin reefs are well-developed in the Changxing Formation in the Kaijiang-Liangping Trough in the northeast Sichuan Basin. …”
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Radiology of viral pneumonia by A. A. Speranskaia, L. N. Novikova, O. P. Baranova, M. A. Vasilieva

“…Objective: to evaluate the clinical and radiological features of viral pneumonia caused by influenza A (H1N1) in 2015–2016.Material and methods. …”
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Analysis of Points of Interest in Hsinchu Old City Blocks Using Space Syntax by Shaofu Li

“…Modern cities’ grid patterns and straight roads connect various scenic spots. …”
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Sparse Convolution FPGA Accelerator Based on Multi-Bank Hash Selection by Jia Xu, Han Pu, Dong Wang

“…To address this issue, we propose a shared feature map cache design for asynchronous convolution in the accelerators presented in this paper. …”
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A novel measurement system for unattended, in situ characterization of carbonaceous aerosols by A. Keller, P. Specht, P. Steigmeier, E. Weingartner

“…To address this issue we have developed the fast thermal carbon totalizator (FATCAT). …”
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Topology-aware pathway analysis of spatial transcriptomics by Siras Hakobyan, Maria Schmidt, Hans Binder, Arsen Arakelyan

“…To support interactive exploration of results, we developed the PSF Spatial Browser, an R Shiny application for visualizing pathway activities, gene expression patterns, and deregulated pathway networks.…”
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Regularities of crustal faulting and tectonophysical indicators of fault metastability by Yu. L. Rebetsky

“…The seismic data show that in the source of a large earthquake, displacement develops as a running band (‘rolling-carpet’ principle). …”
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