Expression of selected epithelial–mesenchymal transition transcription factors in serous borderline ovarian tumors and type I ovarian cancers by Pawel Sadlecki, Jakub Jóźwicki, Paulina Antosik, Marek Grabiec

“…Epithelial ovarian neoplasms are a heterogeneous group including tumor subsets with distinct clinicopathologic and molecular features. Recent evidence from molecular and genomic studies suggests that whereas low-grade serous carcinomas and high-grade serous carcinomas likely develop on two separate pathways, the low-grade serous carcinomas and serous borderline ovarian tumors may represent various stages of the same developmental continuum. …”
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AI-powered simulation-based inference of a genuinely spatial-stochastic gene regulation model of early mouse embryogenesis. by Michael Alexander Ramirez Sierra, Thomas R Sokolowski

“…Understanding how multicellular organisms reliably orchestrate cell-fate decisions is a central challenge in developmental biology, particularly in early mammalian development, where tissue-level differentiation arises from seemingly cell-autonomous mechanisms. …”
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Older adults' needs and preferences for a nutrition education digital health solution: A participatory design study by Ashlee Turner, Victoria M. Flood, Haley M. LaMonica

“…Patient or Public Contribution Older adults actively participated in the development and evaluation process to generate ideas about potential features, functionalities, uses and practicalities of an online nutrition education resource.…”
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AI-Driven Plant Health Assessment: A Comparative Analysis of Inception V3, ResNet-50 and ViT with SHAP for Accurate Disease Identification in Taro by Valeria Maeda-Gutiérrez, Juan José Oropeza-Valdez, Luis C. Reveles-Gómez, Cristian Padron-Manrique, Osbaldo Resendis-Antonio, Luis Octavio Solís-Sánchez, Hector A. Guerrero-Osuna, Carlos Alberto Olvera Olvera

“…The proposed models significantly improve the ability to recognize complex patterns and features, achieving high accuracy and robust performance in disease classification. …”
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Classification of hoarding and comorbid neuropsychiatric symptoms by Sara K. Nutley, Catherine W. Striley, Linda B. Cottler, Joseph Eichenbaum, Rachel L. Nosheny, R. Scott Mackin, Carol A. Mathews

“…Conclusions: Neuropsychiatric symptom patterns among individuals with hoarding are heterogenous in nature and uniquely associated with clinical features and functional outcomes. …”
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Multisensor Remote Sensing and Advanced Image Processing for Integrated Assessment of Geological Structure and Environmental Dynamics by Luo Bin, Rana Waqar Aslam, Iram Naz, Dmitry E. Kucher, Zohaib Afzal, Danish Raza, Rana Muhammad Zulqarnain, Yahia Said

“…The findings indicate that sustainable management of lake requires the consideration of both structural controls and anthropogenic influences, with particular attention to the eastern shore’s development patterns where human activities are concentrated.…”
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Ангари як архітектурний елемент авіаційних музейних комплексів by Yuriy Doroshenko, Alexander Khlyupin, Bohdana Nikolchuk

“…Aim: to determine the design features of hangars in museum complexes, their practical significance and functional purpose. …”
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P4HA2 promotes proliferation, invasion, and metastasis through regulation of the PI3K/AKT signaling pathway in oral squamous cell carcinoma by Zengpeng Chi, Qimin Wang, Xin Wang, Dagang Li, Lei Tong, Yu Shi, Fang Yang, Qingyuan Guo, Jiawei Zheng, Zhenggang Chen

“…Various databases, including TCGA, TIMER, UALCAN, GEPIA, and K-M plotter, along with paraffin-embedded samples, were used to ascertain P4HA2 expression in cancer and its correlation with clinicopathological features. P4HA2 knockdown and overexpression cell models were developed to assess its oncogenic roles and mechanisms. …”
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An Explanation Interface for Healthy Food Recommendations in a Real-Life Workplace Deployment: User-Centered Design Study by Robin De Croon, Daniela Segovia-Lizano, Paul Finglas, Vero Vanden Abeele, Katrien Verbert

“…MethodsAn iterative, user-centered design process guided the development and refinement of the system across 4 phases: (Phase 0) an exploratory qualitative study (N=26) to understand stakeholder needs and initial system impressions, (Phases 1 and 2) rapid prototyping in real-life deployments (N=45 and N=16, respectively) to iteratively improve usability and features, and (Phase 3) a proof-of-principle study with employees (N=136) to evaluate a set of design goals. …”
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Atypical hierarchical brain connectivity in autism: Insights from stepwise causal analysis using Liang information flow by Shan Sun, Fei Wang, Fen Xu, Yufeng Deng, Jiwang Ma, Kai Chen, Sheng Guo, X. San Liang, Tao Zhang

“…These disruptions were detected at multiple hierarchical levels, indicating changes in communication patterns across brain regions. By leveraging features of hierarchical causal connectivity, we achieved high classification accuracy between ASD and healthy individuals. …”
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MACHINE LEARNING TECHNIQUES FOR RETINOPATHY DETECTION IN DIABETIC PATIENTS by Ajay Kushwaha, Ahankari Sachin Suresh, Chennoju Phanindra, Anil Kumar Sahu, Devanand Bhonsle, Yamini Chouhan

“…The core technology involves deep learning algorithms, particularly Convolutional Neural Networks (CNNs), which are designed to identify complex patterns and features within retinal images. These algorithms are trained on extensive datasets of retinal images, allowing them to learn the subtle signs of diabetic retinopathy, such as microaneurysms, hemorrhages, and other vascular anomalies.…”
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Revealing heterogeneity in mild cognitive impairment based on individualized structural covariance network by Xiaotong Wei, Ronglong Xiong, Ping Xu, Tingting Zhang, Junjun Zhang, Zhenlan Jin, Ling Li

“…Significant differences between two subtypes were found in clinical cognition and biomarkers, cerebral atrophy patterns, and enriched genes for metal ion transport and neuron projection development. …”
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Properties of novel biodegradable film from gelatin capsule waste as influenced by various solvents and washing cycles by Pudthaya Kumnerdsiri, Sasina Sanprasert, Anusorn Seubsai, Jaksuma Pongsetkul, Nathdanai Harnkarnsujarit, Saroat Rawdkuen, Samart Sai-ut, Suphat Phongthai, Piyangkun Lueangjaroenkit, Ekasit Onsaard, Ali Muhammed Moula Ali, Thomas Karbowiak, Wanli Zhang, Passakorn Kingwascharapong

“…FTIR spectroscopy revealed differences in bands and patterns between control film (GCWF) and washed films (GCWF Alc and GCWF W). …”
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Has the Three Gorges Reservoir Impacted Regional Moisture Recycling? by Jia Wei, Weiguang Wang, Mingzhu Cao, Jianyun Zhang, Junliang Jin, Guoqing Wang, Hongbin Li, Xiaolong Pan, Zongchao Ye, Adriaan J. Teuling, Shuo Wang

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Whole transcriptome analysis of unmutated sporadic ALS patients' peripheral blood reveals phenotype-specific gene expression signature by Francesca Dragoni, Maria Garofalo, Rosalinda Di Gerlando, Bartolo Rizzo, Matteo Bordoni, Eveljn Scarian, Camilla Viola, Veronica Bettoni, Giuseppe Fiamingo, Danilo Tornabene, Lucia Scanu, Orietta Pansarasa, Luca Diamanti, Stella Gagliardi

“…Classification based on clinical phenotypes could be associated with peculiar gene expression patterns shaped during lifespan, allowing the identification of specific sporadic ALS (sALS) subtypes with less heterogeneous clinical and biological features. …”
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Hybrid Graph Representation and Learning Framework for High-Level Synthesis Design Space Exploration by Pouya Taghipour, Eric Granger, Yves Blaquiere

“…Indeed, modeling HLS-related problems using GNNs that efficiently capture the complex patterns arising from applied pragmas and low-level characteristics of HLS specifications is challenging. …”
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Cyclin D2 – a potential biomarker in uterine corpus endometrial carcinoma through methylation chip and bioinformatic analysis by Lizhen Wang, Lizhen Wang, Wu Qu, Zhifu Yang

“…TCGA datasets were analyzed to explore differential patterns involving mRNA and DNA methylation features associated with CCND2. …”
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Landscape genetics highlights species-specific ecological influences on gene flow in highland frog populations from northeastern Brazil by José Henrique de Andrade Lima, Marco Katzenberger, Marcelo Gehara, Pedro Ivo Simões

“…We conducted a comparative landscape genetics study to assess the influence of geographic and environmental landscape features on genetic differentiation in two ecologically distinct anurans species: Dendropsophus oliveirai, a diminutive treefrog that uses ponds for reproduction and larval development, and Physalaemus cuvieri, a terrestrial frog that breeds in both ponds and rain pools, depositing eggs in foam nests where embryos develop. …”
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Dynamic tensile mechanical properties and damage fracture mechanisms of saturated frozen sandstone by Ming Li, Fuqiang Zhu, Yiwen Mao, Peng Wu, Yanlong Chen, Ketong Wu, Jiazhi Zhang, Hao Yu

“…At lower strain rates, the stress–strain curves display features of ductile deformation, whereas at higher strain rates, they exhibit typical brittle failure behavior. …”
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Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes by Martin V. Hamann, Shweta Godbole, Maisha Adiba, Sabrina M. Leddy, Jelena Navolić, Ghazaleh Tabatabai, Daniel J. Merk, Ulrike C. Lange, Julia E. Neumann

“…Extensive molecular characterization based on gene expression and DNA methylation patterns has solidly established three major ATRT subtypes (MYC, SHH and TYR), which show distinct clinical features, setting the basis for more effective, targeted treatment regimens. …”
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