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Dynamic Synergy Network Analysis Reveals Stage-Specific Regional Dysfunction in Alzheimer’s Disease
Published 2025-06-01“…<b>Result:</b> The key finding are as follows: (1) synergy metrics exhibited lower intra-group coefficient of variation than mutual information metrics, indicating higher computational stability; (2) single-sample reconstruction significantly enhanced the statistical power in intergroup difference detection; (3) synergy metrics captured brain network features that are undetectable by traditional mutual information methods, with more pronounced differences between networks; (4) key node analysis demonstrated spatiotemporal degradation patterns progressing from initial dysfunction in orbitofrontal–striatal–temporoparietal pathways accompanied by multi-regional impairments during prodromal stages, through moderate-phase decline located in the right middle frontal and postcentral gyri, to advanced-stage degeneration of the right supramarginal gyrus and left inferior parietal lobule. …”
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2242
Prognostic model identification of ribosome biogenesis-related genes in pancreatic cancer based on multiple machine learning analyses
Published 2025-05-01“…Single-cell RNA sequencing analysis (GSE155698 dataset) was performed to assess gene expression patterns and module scores. Results Sixty ribosome biogenesis-related prognostic genes were identified in pancreatic cancer. …”
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2243
Expression of selected epithelial–mesenchymal transition transcription factors in serous borderline ovarian tumors and type I ovarian cancers
Published 2018-06-01“…Epithelial ovarian neoplasms are a heterogeneous group including tumor subsets with distinct clinicopathologic and molecular features. Recent evidence from molecular and genomic studies suggests that whereas low-grade serous carcinomas and high-grade serous carcinomas likely develop on two separate pathways, the low-grade serous carcinomas and serous borderline ovarian tumors may represent various stages of the same developmental continuum. …”
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Older adults' needs and preferences for a nutrition education digital health solution: A participatory design study
Published 2024-02-01“…Patient or Public Contribution Older adults actively participated in the development and evaluation process to generate ideas about potential features, functionalities, uses and practicalities of an online nutrition education resource.…”
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2245
Application of EMD, ANN and DNN for Self-Aligning Bearing Fault Diagnosis
Published 2018-01-01“…Time domain and time-frequency domain features are then extracted which are used to implement the neural networks through the pattern recognition tool in MATLAB. …”
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2246
Dermatomyositis-Associated Interstitial Lung Disease Misdiagnosed as Pulmonary Tuberculosis
Published 2025-01-01“…Further testing revealed positive antinuclear antibodies, anti-Mi-2, and anti-Jo-1 antibodies, restrictive lung pattern on pulmonary function test and high-resolution computer tomography (HRCT) features of non-specific interstitial pneumonia (NSIP), confirming dermatomyositis-associated interstitial lung disease (DM-ILD). …”
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A spatiotemporal model for urban taxi Origin–Destination prediction based on Multi-hop GCN and Hierarchical LSTM
Published 2025-09-01“…Specially, DBSTNet models pick-up and drop-off patterns via transposed OD matrices and employs 2 independent branches to separately capture spatial–temporal features. …”
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2248
The effective landscape design parameters with high reflective hardscapes: guidelines for optimizing human thermal comfort in outdoor spaces by design -a case on hot arid climate w...
Published 2025-05-01“…These results highlight the importance of balancing hardscape and softscape areas, integrating vegetation and water features, and utilizing light-colored materials in dispersed patterns. …”
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Full-length ribosome density prediction by a multi-input and multi-output model.
Published 2021-03-01“…Most of the existing computational approaches for modeling translation elongation from ribosome profiling data mainly focus on local contextual patterns, while ignoring the continuity of the elongation process and relations between ribosome densities of remote codons. …”
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2250
Unveiling a novel model of cell senescence-related genes for prognostic assessment and immunotherapeutic insights in gastric cancer
Published 2025-02-01“…The mRNA expression patterns, gene mutations, and clinical information of STAD were obtained from the cancer genome atlas (TCGA) and gene expression omnibus (GEO). …”
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2251
Calculation and Experimental Study of the Dynamics of the Track Mover Bypass of a Cross-Country Transport Vehicle
Published 2024-12-01“…Thus, based on the results of the studies, the features of dynamic processes in the track mover were established, the main patterns of the formation process of transverse oscillations, their dependence on the design parameters of the bypass and various operational factors were revealed.…”
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2252
Patho-Ecological Distribution and Genetic Diversity of <i>Fusarium oxysporum</i> f. sp. <i>cubense</i> in Malbhog Banana Belts of Assam, India
Published 2025-03-01“…The morpho-cultural characterization of Foc isolates showed large variations in colony morphological features, intensity, and pattern of pigmentation, chlamydospores, and conidial size. …”
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Tectonic geomorphological evidence of late Quaternary segmented activity along the northern margin fault of Lajishan
Published 2025-03-01“…HI spatial distribution patterns along the North Lajishan fault show multiple high-value zones within piedmont basins. …”
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2255
Cognitive and neuropsychiatric disorders in extrapyramidal diseases
Published 2014-01-01“…The basis for these disorders are most commonly dysfunction of one or a few parallel frontostriatal circuits combining the basal ganglia with the thalamus, limbic structures, frontal and other cortical regions into the uniform functional system. The pattern of neuropsychological disorders has both specific and common features, the discussion of which is the subject matter of this paper. …”
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2256
Imaging cherubism: Radiologic hallmarks of a rare jaw anomaly
Published 2025-07-01“…Based on the radiological features grading systems have been developed that help decide the management.…”
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2257
SLAMF receptors: key regulators of tumor progression and emerging targets for cancer immunotherapy
Published 2025-05-01“…Abstract The signaling lymphocytic activation molecule family (SLAMF) consists of nine distinct cell surface receptors predominantly expressed on immune cells, each characterized by unique structural features, expression patterns, downstream signaling pathways, and biological functions. …”
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Classification of Individuals With COVID-19 and Post–COVID-19 Condition and Healthy Controls Using Heart Rate Variability: Machine Learning Study With a Near–Real-Time Monitoring C...
Published 2025-08-01“…A secondary objective was to assess the feasibility of a near–real-time health monitoring system based on these patterns using wearable-derived HRV data. …”
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From lab to field with machine learning – Bridging the gap for movement analysis in real-world environments: A commentary
Published 2024-09-01“…Finally, automated classification (e) refers to the process of developing a predictive model that assigns input features of data samples to predefined categories or classes using supervised ML. …”
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Early and Delayed Rebound Intracranial Hypertension following Epidural Blood Patch in a Case of Spontaneous Intracranial Hypotension
Published 2022-01-01“…Following EBP for treatment of SIH, new onset of headache having a different pattern and location should always be monitored for the occurrence of RIH. …”
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