Intratumoral heterogeneity and drug resistance in cancer by Yue-Chun Fu, Shao-Bo Liang, Min Luo, Xue-Ping Wang

“…Understanding the role of intratumoral heterogeneity, it becomes clear that a single therapeutic agent or regimen may only be effective for subsets of cells with certain features, but not for others. This necessitates a shift from our current, unchanging treatment approach to one that is tailored against the killing patterns of cancer cells in different clones. …”
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First retrogressive thaw slump (RTS) inventory for the Kanin Peninsula (NW Russia) by Ionut Cristi Nicu, Lena Rubensdotter, Hakan Tanyaș, Luigi Lombardo

“…Using 2022 ESRI Wayback satellite imagery, we manually digitized 900 RTS polygons on the Kanin Peninsula (NW Russia), categorizing them into 633 inactive and 267 active features based on morphology and vegetation patterns. …”
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DEEP CRUSTAL STRUCTURE AND MODEL OF NEORCHAEAN EVOLUTION OF THE NORTH AMERICAN CRATON by M. V. Mints, T. B. Afonina

“…The Neoarchaean North American Craton is one of a series of similar phenomena that occurred ~2.75 Ga ago in a number of continental regions. The most important features, repeated to a certain degree in tectonic units of this type, are: (1) synchronous formation between 2.79 and 2.58 Ga; (2) mainly intracontinental development; (3) the prevalence of oval‐shaped synformal tectonic structures of different ranks with some form of concentric zoning; (4) high‐temperature magmatism (usually with the participation of enderbite‐charnockites and gabbro‐anorthosites) and metamorphism of the granulite facies; (5) a frequently repeated combination of high‐grade (granulite and high‐ temperature amphibolites facies) and low‐ or moderate‐grade (greenschist and epidote‐amphibolite facies) meta‐ morphic rocks; (6) the lower‐crust granulite‐basaltic layer that had formed and was deformed at the final stage of endogenic activity; (7) a thick lithosphere (the lithospheric keel reaches a depth of 250–350 km).…”
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Classifying Emotionally Induced Pain Intensity Using Multimodal Physiological Signals and Subjective Ratings: A Pilot Study by Eun-Hye Jang, Young-Ji Eum, Daesub Yoon, Sangwon Byun

“…SC features emerged as key biomarkers, while valence and arousal offered complementary insights, supporting the development of personalized, psychologically informed pain assessment systems.…”
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Assessment of economic well-being in South Africa based on remote sensing transfer learning by L. Wang, L. Wang, T. Long, T. Long, E. Adam

“…CNNS are trained to predict nighttime light intensity, act as proxies for economic activity, while learning to recognize environmental features. Patterns indicating economic activity and environmental conditions can be identified from daytime images alone. …”
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Hierarchical Embedded System Based on FPGA for Classification of Respiratory Diseases by Trong-Thanh Han, Kien Le Trung, Phuong Nguyen Anh, Anh Do Trung

“…Objectives: This research aims to design and develop a hierarchical embedded system that utilizes respiratory sound features for diagnosing COPD and other respiratory disorders. …”
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Hydroformer: Frequency Domain Enhanced Multi‐Attention Transformer for Monthly Lake Level Reconstruction With Low Data Input Requirements by Minglei Hou, Jiahua Wei, Yang Shi, Shengling Hou, Wenqian Zhang, Jiaqi Xu, Yue Wu, He Wang

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Language mixing in traditional medicine manuscripts: public access to health knowledge and practices in Indonesia by Ellyana Hinta, Mirna Yusuf, Asna Ntelu, Muassomah, Rasuna Thalib

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Risk factors of incident in-hospital pulmonary embolism and its outcomes: autopsy study data by O. Ya. Vasiltseva, I. N. Vorozhtsova, A. V. Krestinin, E. V. Stefanova, R. S. Karpov

“…Overall, the risk of fatal PTE was explained by RF patterns (56,0%), inadequate treatment (43,9%), and other factors (0,1%). …”
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In vivo electrophysiology recordings and computational modeling can predict octopus arm movement by Nitish Satya Sai Gedela, Ryan D. Radawiec, Sachin Salim, Julianna Richie, Cynthia Chestek, Anne Draelos, Galit Pelled

“…This study demonstrates how real-time motor behaviors can be predicted and distinguished, contributing to the development of brain-machine interfaces. The ability to accurately model and predict complex movement patterns has broad implications for advancing technologies in robotics, neuroprosthetics, and artificial intelligence, paving the way for more sophisticated and adaptable systems.…”
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A practical method to predict the critical zone of coastal cliffs at high risk of failure considering the effects of fluid–structure interaction by Ali Khosravifardshirazi, Akbar A. Javadi, Ali Johari, Mohammad Akrami

“…Validated numerical simulations demonstrate strong agreement with observed deformation patterns, confirming model reliability and predictive capability. …”
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Perception of Space and Sense of Place among Elderly Residents of the Solovetsky Village by Regina A. Pshenko

“…This article examines and analyses the results of a survey of the elderly population of the Solovetsky village, identifying the features and patterns of sensory-emotional perception of space. …”
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The impact of targeted advertising on the consumer by E. A. Ponomareva, E. A. Popova, N. R. Ponomarev

“…Surveys were conducted among users to identify their attitudes towards targeted advertising and its impact on their purchasing decisions, statistical methods were used to analyze data and identify patterns in user behavior and the effectiveness of targeted advertising.Results and discussion. …”
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Genomic survey, gene expression analysis and structural modeling suggest diverse roles of DNA methyltransferases in legumes. by Rohini Garg, Romika Kumari, Sneha Tiwari, Shweta Goyal

“…These results provide valuable insights into role of various domains in molecular recognition and should facilitate mechanistic understanding of their function in mediating specific methylation patterns. Further, the comprehensive gene expression analyses of MTases in legumes provided evidence of their role in various developmental processes throughout the plant life cycle and response to various abiotic stresses. …”
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Posthypoxic encephalopathy in patients after cardiac surgery: etiological, pathogenetic, and clinical aspects (a literature review) by T. M. Alekseeva, O. A. Portik, M. P. Topuzova

“…To determine the individual management tactics for such patients, combining both successful surgical treatment, by reducing perioperative stress, and prevention of cerebral complications, it is necessary to analyze the patterns of their development. The role of pathophysiological risk factors, including preoperative, perioperative and postoperative ones, for posthypoxic encephalopathy, is considered. …”
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Revolutionizing Sperm Analysis with AI: A Review of Computer-Aided Sperm Analysis Systems by Francisco J. Baldán, Diego García-Gil, Carlos Fernandez-Basso

“…These advanced systems offer significant advantages, including enhanced objectivity, improved consistency over manual methods, and the ability to detect subtle predictive patterns not discernible by human observation. The emergence of extensive open datasets and big data analytics has enabled the development of more robust models. …”
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Exploring the spatiotemporal dynamics and resilience assessment of urban networks from the perspective of population flow. by Jiulin Li, Wenhui Lin, Jinlong Chu

“…The spatial patterns of population mobility serve as a critical indicator for urban network characterization, providing an essential foundation for resilience assessment. …”
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Neurocinematic therapy - An interdisciplinary perspective by Wolfgang Mastnak

“…The present study identifies seven potentially therapeutic features of movie experience which suggest a preliminary scientific framework: i) change of pathological cognitive patterns and compulsive thought, ii) integration of fragmentised identities, iii) intuitive development of self-therapeutic measures, iv) re-balancing of inner calmness and dynamic lifestyles, v) biographical work and episodic exposure training, vi) synchronisation of movie rhythms, life rhythms and inner rhythms, and vii) clinical trance as well as movie-based auto-hypnosis. …”
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Sentiment analysis of user reviews: exploring Duolingo and Babbel in English language learning by Husnat Ahmed Tabssam, Saima Akhtar Chattha, Muhammad Farooq Javeed, Ali Hayat

“…The research reveals distinct sentiment clusters, network metrics, and user engagement patterns, highlighting how sociocultural factors and user experiences shape perceptions of app functionality and effectiveness. …”
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Advanced neural activity mapping in brain organoids via field potential imaging with ultra-high-density CMOS microelectrode arrays by Remi Yokoi, Naoki Matsuda, Yuto Ishibashi, Ikuro Suzuki

“…FPI also enabled frequency-domain analyses, revealing region-specific activity, including distinct gamma-band patterns. In midbrain–striatal assembloids, 4-aminopyridine enhanced interorganoid connectivity.ConclusionThis single-cell-resolved, large-scale recording approach using UHD-CMOS MEAs enables detailed analysis of network connectivity, propagation dynamics, and frequency features. …”
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