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Distribution patterns of fungal community diversity in the dominant tree species Dacrydium pectinatum and Vatica mangachapoi in tropical rainforests
Published 2025-06-01“…According to the Mantel test, soil pH mainly influenced roots, while the main driving factors for leaves were rainfall and temperature. …”
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2′-Fucosyllactose mitigates cognitive deficits in Alzheimer models: targeting amyloid pathology, oxidative stress, and synaptic plasticity
Published 2025-08-01“…This study aimed to investigate the therapeutic potential of 2′-FL in an aging mouse model of AD and to explore the underlying mechanisms involved.Methods5xFAD transgenic mice were treated with 2′-FL and assessed for cognitive function using the Morris water maze and Y-maze tests. …”
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Association between thyroid stimulating hormone levels and nonproliferative diabetic retinopathy: a cross-sectional study
Published 2025-04-01“…The demographic data and biochemical parameters were compared between groups using the Student’s t - test or the Mann‒Whitney U test, anthropometric measurements, thyroid function, and NPDR were evaluated, and the associations between TSH and NPDR were assessed using logistic regression models. …”
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Forecasting the gross municipal product taking into account the investment component
Published 2024-10-01“…The research methodology includes methods of relative values, dynamics analysis, and regression analysis; a classical two-factor (labor and capital) production function of Cobb- Douglas was used to describe the revealed patterns and build a forecast, and trend models was constructed. …”
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Sleep efficiency and event−related potentials in patients with depression: the mediating role of serum C-reactive protein
Published 2025-07-01“…CRP mediated the association between SE and P3b latency.ConclusionLow SE with MDD was associated with chronic inflammation and impaired cognitive function, suggesting that inflammation may act as a potential mediating factor in the relationship between SE and impaired cognitive function.…”
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Oral administration of anti-lipopolysaccharide factor isoform 3 via the bait microalga for controlling bacterial infection of Atlantic Bay scallop (Argopecten irradians)
Published 2024-12-01“…Combined with changes in immune factors and endotoxin, it indicated that exogenous ALFPm3–2 played antimicrobial and anti-inflammatory functions in the guts of bay scallops. …”
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Increased Incidence of Chronic Obstructive Pulmonary Disease in Women Due to Long-Term Passive Smoking
Published 2025-08-01“…Participants underwent comprehensive assessments including pulmonary function tests (spirometry), hematological analyses, and structured questionnaires evaluating COPD symptoms and passive smoking exposure. …”
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Positive selection analyses identify a single WWE domain residue that shapes ZAP into a more potent restriction factor against alphaviruses.
Published 2024-08-01“…The host interferon pathway upregulates intrinsic restriction factors in response to viral infection. Many of them block a diverse range of viruses, suggesting that their antiviral functions might have been shaped by multiple viral families during evolution. …”
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High-Titer Rheumatoid Factor is Associated with Worse Clinical Outcomes and Higher Needs for Advanced Therapies in Rheumatoid Arthritis Under Real-Life Conditions
Published 2024-12-01“…Bivariate (Student’s t and chi-squared tests) tests and multiple logistic and linear regression analyses were conducted. …”
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A randomized controlled trial of statin therapy effect on androgen status and erectile function in men with high and very high cardiovascular risk (TRISTAN): rationale and study pr...
Published 2025-06-01“…Additionally, to assess the association between sex hormone levels, erectile function parameters, and traditional cardiovascular risk factors, arterial stiffness, and endothelial function in this patient category.Material and methods. …”
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Cycling training for endothelial dysfunction correction and atherosclerotic risk factor modification in young males (data from Tomsk City university students’ survey)
Published 2006-10-01“…To assess physical training (PT) effect on NO-dependent vascular and autonomous tonus disturbances in male students with atherosclerosis risk factors (ARF) and endothelial dysfunction (ED), as well as to develop the optimal PT protocol. …”
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Hepatoprotective potential of Chrysin in a rat model of isoniazid- and rifampicin-induced hepatic injury: suppression of matrix metalloproteinase and transforming growth factor β
Published 2025-01-01“…In this study, Group VI Silymarin (100 mg/kg, p.o.) functioned as the standard drug. The blood was drawn as the study was done, and tests for oxidative stress indicators, haematological parameters, biochemical parameters, and pro-inflammatory cytokines were performed. …”
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Coastal Urban Ecological Security Pattern Identification Integrating Land Subsidence Factors: A Deep Learning-Based Case Study of Zhuhai City
Published 2025-04-01“…Using Zhuhai City as a case study, we analyzed 30 environmental variables, including historical land subsidence data, topography, soil distribution, land use, climatic factors, and human activity indicators. The methodology consisted of four main steps: (1) correlation and principal component analyses to identify key factors and reduce dimensionality; (2) development of a multilayer perceptron (MLP) deep learning model with three fully connected hidden layers using ReLU activation functions and dropout regularization to predict ecological pattern types; (3) comparison of four fusion methods (weighted average, nonlinear sigmoid transformation, information entropy, and principal component analysis) to integrate prediction results; and (4) spatial analysis of the relationship between land subsidence and ecological security patterns using chi-square tests and spatial overlay analysis. …”
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Influence of Urinary Incontinence Related Factors on Health-Related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
Published 2025-06-01“…Notably, greater UI severity corresponded to more substantial impairments in HRQoL, with severe cases reporting greater negative effects on daily functioning. These findings underscore the importance of routine screening for UI in COPD patients and the implementation of targeted continence care strategies to enhance overall quality of life.Plain Language Summary: This study highlights significant correlations between UI, HRQoL, and factors such as age, BMI, and breathlessness. …”
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APOE gene polymorphism as a potential predictor of postoperative cognitive dysfunction in colon cancer surgery under general anesthesia
Published 2025-01-01“…Seven days after surgery, a statistically significant impairment of cognitive functions was found in patients with the APOE ε4 allele in their genotype (p = 0.007). …”
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Assessing Pulmonary Function in Children and Adolescents After Cancer Treatment: Protocol for a Multicenter Cohort Study (Swiss Childhood Cancer Survivor Study FollowUp–Pulmo)
Published 2025-04-01“… BackgroundChildhood cancer survivors (CCS) are at risk of pulmonary dysfunction due to cancer treatments, but evidence on prevalence and risk factors remains limited. Most previous studies had small sample sizes or retrospective study designs, little information about treatments, or a lack of standardization of pulmonary function tests (PFTs) or limited their investigation to certain PFTs. …”
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Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regenera...
Published 2025-01-01“…These effects substantially enhance motor function in SCI rats, positioning it as a promising candidate for future clinical applications. …”
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Metagenomics-based analysis of microbial community structure and functional differences in fermented grains of Jiang-flavored baijiu from different production regions and policy re...
Published 2025-07-01“…By applying metagenomics technology and various analytical and statistical methods, we analyzed the community structures of bacteria and fungi in fermented grains, their functional genes, and their correlations with environmental factors.ResultsWe identified 1063 bacterial genera and 411 fungal genera. …”
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