The effects of frailty, mental health, and cardiac function on quality of life in patients undergoing transcatheter aortic valve replacement by Jinyao Wang, Jun Cui, Xuemei Yang, Shuangyan Tu, Ying Wang, Yan Jiang, Lihong Zhao, Mao Chen, Zhonglan Chen, Yun Bao

“…However, the relationships between frailty, mental health, cardiac function, and QoL in patients after TAVR have not been well-studied. …”
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High-density lipoprotein cholesterol subfraction HDL2 is associated with improved endothelial function in systemic lupus erythematosus by Tze Ping Loh, Lieng Hsi Ling, Anselm Mak, Lingli Gong, Nien Yee Kow, Chun En Yau, Sen Hee Tay, Ainsley Ryan Yan Bin Lee, Cheryl Kai Ting Chua, Wan Ling Cheng, Avery Joy Li Chia, Shi Yin Wong, Bernett Teck Kwong Lee

“…We tested the hypothesis that lipoprotein subfractions are independently associated with FMD.Methods Forty-one consecutive adult patients with SLE without known cardiovascular risk factors or disease were recruited in this cross-sectional study. …”
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Risk factors for diabetic autonomic cardiovascular neuropathy in children and adolescents with type 1 diabetes mellitus by Maria Rustemovna Shaidullina, Farida Vadutovna Valeeva, Eduard Zakirzyanovich Yakupov

“…Heart rate variability (HRV) was assessed in 101 subjects with type 1 diabetes mellitus aged 5?17 y.o. in 4 functional tests. Subjects with 3 positive tests out 4 were considered positive for DACN. …”
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Maternal Risk Factors, Patterns, and Outcomes of Antenatal Congenital Anomalies: A Hospital-Based Study by Seham M. Abufraijeh, Ahlam M. Al-Kharabsheh, Ala N. Uwais, Malek Al Qasem

“…<b>Background/Objective</b>: Congenital anomalies (CAs) are structural or functional abnormalities contributing to global neonatal morbidity and mortality. …”
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Markers of placental function correlate with prevalence and quantity of nucleated fetal cells in maternal circulation in normotensive term pregnancies by Heidi E. Fjeldstad, Daniel P. Jacobsen, Guro M. Johnsen, Meryam Sugulle, Angel Chae, Sami B. Kanaan, Hilary S. Gammill, Anne Cathrine Staff

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The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis. by Patrick A Carroll, Brian W Freie, Pei Feng Cheng, Sivakanthan Kasinathan, Haiwei Gu, Theresa Hedrich, James A Dowdle, Vivek Venkataramani, Vijay Ramani, Xiaoying Wu, Daniel Raftery, Jay Shendure, Donald E Ayer, Charles H Muller, Robert N Eisenman

“…Our genomic and functional analyses identify loci directly bound by MLX involved in these processes, including metabolic targets, obligate components of male-specific GC development, and apoptotic effectors. …”
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Clinicopathologic characteristics of kidney and other organs in ANCA-associated vasculitis patients and outcomes and risk factors by LIU Guo-ping, WANG Chun-yan, XU Li-bin, CAO Sai-xia, GUO Yan

“…Objective To investigate the clinicopathological characteristics of antineutrophil cytoplasmic antibody(ANCA)-associated vasculitis(AAV) with renal involvement and other organs in Inner Mongolia People’s Hospital and to analyze the outcomes and risk factors.Methods Clinical features of 123 cases of AAV hospitalized from September 1995 to September 2009 were reviewed retrospectively.According to the ANCA test results,the patients were divided into cytoplastic ANCA positive group(C-ANCA group) and perinuclear ANCA positive group(P-ANCA group).The differences in clinicopathological manifestations,laboratory tests and functional outcomes were observed.The death and renal failure were the end point in the 5 years.Results Of 123 AAV patients,63 were male,and 60 were female(the male and female ratio was 1.05:1).The age ranged from 38-82 years old.82.9%of them(102 cases) were in the range of 50-82 years old(mean 60 ± 22).109 were PANCA positive,and 14 were C-ANCA positive.Renal involvement and lung involvement were similar between C-ANCA group and P-ANCA group.The prevalence of respiratory,gastrointestinal,articular and ophthalmic involvements was higher in P-ANCA group than in C-ANCA group(P<0.05).There was no significant difference in otologic,cutaneous,muscular and neural involvements between two groups.Of the 62 cases receiving renal biopsy,crescent nephritis was found in 30 cases,glomerrular segmental necrosis in 12 cases,mesenteria crescent in 15 cases,and fabric crescent with focal segmental sclerosis in 15 cases.There was no significant difference in mortality and renal failure between two groups.Respiratory failure and multiple organ dysfunctions were relative mortality factors in the analysis of age,sex,types of ANCA,fever,renal failure,respiratory and lung infection.There were significant relationships between clinical terminus with serum creatinine,erythrocyte sediment rate,plasma-albumin and hemoglobin.Logistic regression analysis revealed that serum creatinine level and erythrocyte sediment rate at the baseline were associated with poor outcomes.Conclusions AAV is common in elders and men with multiple organ involvement P-ANCA positive patients are more than C-ANCA patients.The number of organ involvements in P-ANCA group is greater than that in C-ANCA group.The disease spectrum is different in these two groups.Respiratory failure and multiple organ dysfunctions were relative mortality factors.…”
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Assessing the Elderly Health-related Unmet Needs and Some Related Factors in Hamadan City, Iran by Fatemeh Mansouri-Shad, Parvin Cheraghi, Sediqheh Mafakheri-Bashmagh, Qhadir Nouri, Zahra Cheraghi

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Risk Factors for Chronic Pain in Women: The Role of Violence Exposure in a Case–Control Study by Allison Uvelli, Erica Pugliese, Fabio Ferretti

“…Methods: A case–control study (December 2023–June 2024) used odds ratios and Fisher’s exact test to explore risk factors associated with chronic pain. …”
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Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor. by Caitlin M Conboy, Christiana Spyrou, Natalie P Thorne, Elizabeth J Wade, Nuno L Barbosa-Morais, Michael D Wilson, Arindam Bhattacharjee, Richard A Young, Simon Tavaré, Jacqueline A Lees, Duncan T Odom

“…In contrast, we found minimal mRNA expression perturbations in this core set of E2f4 bound genes in the liver, kidney, and testes of E2f4 null mice. Thus, the regulatory mechanisms maintaining quiescence are robust even to complete loss of conserved transcription factor binding events.…”
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Factors of coxitis progression in patients with axial spondyloarthritis. Results of a two-year dynamic observation by E. M. Agafonova, Sh. Erdes, T. V. Dubinina, A. B. Demina, A. V. Smirnov

“…According to studies conducted in the Russian Federation, the main factors leading to disability of patients with axial spondylitis (acSpA) is coxitis.The aim of our study was to evaluate the factors of radiographic progression of coxitis in patients with axial spondylitis.Material and methods. …”
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Annual Dynamics of Phytoplankton Communities in Relation to Environmental Factors in Saline–Alkaline Lakes of Northwest China by Yuying Ma, Linghui Hu, Ruomei Ma, Liting Yang, Qiang Huo, Yong Song, Xuyuan Lin, Zhen Sun, Sheng’ao Chen, Daoquan Ren

“…Biodiversity indices were calculated, and redundancy analysis (RDA), Spearman’s correlation analysis, and Mantel test were carried out to assess the functional community structure of phytoplankton and its environmental drivers. …”
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Aspergillus fumigatus-Associated Disease Spectrum, Virulence Factors, Pathogenicity, and Currently Used Diagnostic Approaches by Priya Koundal, Sunita Manhas, Shakeel Ahmed Mohammed, Kajal, Ajaydeep Singh, Jay Punjani, Shahbaz Aman, Adesh K. Saini

“…To dominate the human body and escape the human immune system, A. fumigatus produces a number of virulence factors as well as pathogenicity determinants to establish disease. …”
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Factors Affecting the Health-Related Quality of Life of Korean Adult Workers: An Analysis by Age Group by Inkyoung Park, Youngho Kim

“…Following guidelines for complex sample design, frequency analyses, group difference tests, and multiple regression analyses were conducted using SPSS version 24.0. …”
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The clinical efficacy and influencing factors of uterine artery embolization in the treatment of different types of uterine adenomyosis by Wen-Jiang Wei, Zuo-Fu Tian, Hao Liu, Cheng-Jiang Xiao

“…In this study, the patients were divided into two groups based on magnetic resonance imaging (MRI) test. Their serum CA125 level was detected, and the degree of symptom relief and health index were evaluated, aiming to explore the clinical efficacy and influencing factors of UAE in the treatment of adenomyosis. …”
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Self-Movement Screening using the Symmio Application is Reliable and Valid for Identifying Musculoskeletal Risk Factors by Kyle Matsel, Jonathan Kirsch, Tessa Netelbeek, Rolando Rodriguez, Ervin Velic, Kate Schwartzkopf-Phifer

“…The validity of Symmio was determined by comparing self-screen performance dichotomized as pass or fail with the reference standard of pain with movement, failure on the Functional Movement Screen™, and asymmetry on the Y Balance Test-Lower Quarter™ using three separate 2x2 contingency tables…”
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Relapse and associated factors among psychiatric patients in Africa: a systematic review and meta-analysis by Belete Birhan, Gidey Rtbey, Kelemu Abebe Gelaw

“…This phenomenon can adversely affect the prognosis of the disorder, the functionality of individuals, and may even increase the overall costs of treatment. …”
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Soluble human macrophage factors are able to inhibit TGF-β-induced differentiation of lung fibroblasts by A. A. Maksimova, E. Ya. Shevela, L. V. Sakhno

“…To do this, TGF-β (inducing differentiation factor) and conditioned macrophage medium were added to fibroblast cultures. …”
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Рrediction risk factors of gastroesophageal reflux disease in children and adolescents with chronic gastroduodenal pathology by L. M. Boiarskа, К. А. Ivanova

“…The following methods were conducted: clinical and medical history, instrumental - fibroesophagogastroduodenoscopy, intragastric pH-metry, ambulatory around-the clock pH monitoring in the esophagus, functional - Holter cardiac monitoring, respiratory HELIK urease test, mathematics and statistics - variational statistics, correlation analysis, binary logistic regression and multivariate regression analysis. …”
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The transcription factor PbeNAC83 positively regulates the Valsa canker resistance in apple and pear by DOU Zhiqi, CAI Minrui, DU Chenglong, HU Huanhuan, ZUO Cunwu

“…As a vital plant-specific transcription factor family, NAC factors are significantly involved in this process. …”
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