Evaluation of the effects of thyroid functions on frailty in geriatric patients using the Edmonton, SOF and FRAIL Scales by Galip Can Uyar, Mustafa Kemal Kılıç

“…Comprehensive geriatric assessments were conducted, including detailed medical histories, sociodemographic data collection, and thyroid function tests. Frailty was assessed using the SOF, EFS, and FRAIL scales. …”
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The interplay of SARS-CoV-2 evolution and constraints imposed by the structure and functionality of its proteins. by Lukasz Jaroszewski, Mallika Iyer, Arghavan Alisoltani, Mayya Sedova, Adam Godzik

“…By the analysis of close to 200,000 genomes we show that the patterns of the SARS-CoV-2 virus mutations along its genome are closely correlated with the structural and functional features of the encoded proteins. Requirements of foldability of proteins' 3D structures and the conservation of their key functional regions, such as protein-protein interaction interfaces, are the dominant factors driving evolutionary selection in protein-coding genes. …”
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Plasma Extracellular Vesicles Biomarkers Linked to Lower Muscle Mass, Function and Physical Performance in Sarcopenia by Ji Yeon Kim, Tae‐Hwan Gil, Hyo Gyeong Lee, Ji‐Won Shin, Dong‐Hyun Jang, Hyeon Soo Kim, Seung Shin Park, Sang Wan Kim, Chan Soo Shin, Sung Hye Kong, Ok Hee Jeon

“…Hand grip strength was measured using a hydraulic hand dynamometer for muscle function and physical performance based on the Short Physical Performance Battery (SPPB), walking speed and the five‐time‐sit‐to‐stand test. …”
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The Relationship Between Core Stability, Muscular Endurance, and Static Balance, and Shooting Function in Military Soldiers by Saied Nourizadeh, Mona Mirjani, Hamidreza Naserpour

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Investigation of Withdrawal, Controlling Difficulty, Disorder in Functionality, and Social Isolation in Problematic Internet Use in Adolescents by Sema Bayraktar, Merve Boşat Sönmez

“…In addition, the study determined that the relationship between impairment of functioning and social Isolation was significant. When the coefficients related to path analysis were tested, it was found that the effect of impairment of functioning on deprivation was not statistically significant, whereas the effect of control difficulty and social isolation on deprivation was statistically significant. …”
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Functional analysis and signaling pathway enrichment analysis of genes associated with Alzheimer’s disease and Parkinson’s disease by N. Yu. Chasovskikh, A. Yu. Grechishnikova, D. V. Smirnov

“…ClueGO plugin was used for functional and pathway enrichment analysis of genes based on the hypergeometric test. …”
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Comparison of perceived family state and functioning among individuals with depression and general population in Southern Thailand. by Jarurin Pitanupong, Kwanpond Traivaranon, Napakkawat Buathong

“…Data analysis involved descriptive statistics, Chi-square or Fisher's exact test, Wilcoxon rank sum test and Student's t-test.…”
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Physical Fitness, Executive Functions, and Academic Performance in Children and Youth: A Cross-Sectional Study by Valter Fernandes, Arthur Silva, Andrea Carvalho, Sidarta Ribeiro, Andrea Deslandes

“…A total of 131 students (49% female) aged 10–15 years from a public school in Rio de Janeiro were assessed in executive functions (hearts and flowers, Corsi’s block, and digit span tasks), academic performance (Portuguese, reading, math, and overall school grade), physical tests (touch test disc, agility, lower limb and upper limb explosive strength), and anthropometric measurements. …”
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THE SEVERITY OF THE COURSE, RATHER THAN IMPAIRED EXTERNAL RESPIRATORY FUNCTION, DETERMINES THE OUTCOME OF COPD TREATMENT by V.V. Bilko

“…All patients underwent assessment of the function of external respiration, assessment of quality of life by SF-36, SGRQ questionnaires, severity of dyspnoea and severity of symptoms - mMRC and SBP test, BODE index and predicted survival for 4 years were calculated. …”
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The mediating effect of anxiety and depression on the association between adverse experiences and executive functioning in young adults by Juan Francisco Palomares Gómez, Anyerson Stiths Gómez Tabares, Catalina Gallego Montes

“…Conclusion: ACEs have a direct and prolonged effect on emotional well-being, however, emotional factors alone may not mediate impairments in executive functioning.  …”
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Patellofemoral Pain (Ⅱ): Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability and Health by The Academy of Orthopaedic Physical Therapy of the American Physical Therapy Association

“…The Academy of Orthopaedic Physical Therapy of the American Physical Therapy Association(APTA)created clinical practice guidelines on patellofemoral pain(PFP)based on the International Classification of Functioning, Disability and Health(ICF).Firstly, the guidelined describes the formulation method, International Classification of Diseases(ICD)-10 codes and ICF codes corresponding to PFP.In addition, the guidelines reviewed the latest peer-review literature to grade different levels of evidence, and provided recommendations on assessment and physical therapy for patellofemoral pain with recommendation grades, which were divided into three parts:1)Impairment/function-based diagnosis: prevalence and incidence, pathoanatomical features, risk factors, diagnosis and classifications(overuse/overload without other impairment, muscle performance deficits, movement coordination deficits, and/or mobility impairments)and differential diagnosis.2)Examination: outcome measures, activity limitations, physical impairment. …”
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Dynamic Functional Ability in Lacrosse Players in Relation to Development of Sport-Related Onset of Musculoskeletal Pain by Zane Thompson, Joseph G. Wasser, Kevin R. Vincent, Heather K. Vincent

“… # Purpose The purposes of this study were to: 1) determine whether age and sex differences exist in dynamic physical function tests and drop jump performance among lacrosse players, and 2) determine whether pre-seasonal physical function scores predict onset of either lower extremity or low back pain over time…”
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Association of menarche, menopause, and reproductive history with cognitive performance in older US women: a cross-sectional study from NHANES 2011–2014 by Anquan Hu, Lu Xiong, Huijun Wei, Liangyan Yuan, Yumeng Li, Heyan Qin, Feng Chen, Tao Liu

“…The cognitive performance was assessed by the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) Word Learning sub-test, Animal Fluency test (AFT), and Digit Symbol Substitution Test (DSST), in relation to reproductive history variables like age of menarche, menopause, reproductive span, number of pregnancies, and parity. …”
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Protein-bound uremic toxin clearance as biomarker of kidney tubular function in diabetic kidney disease by Sabbir Ahmed, Rolf W. Sparidans, Robin W. M. Vernooij, Silvia M. Mihaila, Roel Broekhuizen, Roel Goldschmeding, Tri Q. Nguyen, Rosalinde Masereeuw, Karin G. F. Gerritsen

“…We here hypothesize that PBUT clearance may be a sensitive tubular function marker, and tested this in a DKD mouse model and in type 2 diabetic patients. …”
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The association of systemic microvascular changes with lung function and lung density: a cross-sectional study. by Bianca Harris, Ronald Klein, Michael Jerosch-Herold, Eric A Hoffman, Firas S Ahmed, David R Jacobs, Barbara E K Klein, Tien Y Wong, Joao A C Lima, Mary Frances Cotch, R Graham Barr

“…Measures of microvascular function included retinal arteriolar and venular caliber, urine albumin-to-creatinine ratio and, in a subset, myocardial blood flow on magnetic resonance imaging. …”
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Impact of nutritional status and pulmonary function on short- and long-term overall survival in hemodialysis patients. by Özge Aydın Güçlü, Hasim Atakan Erol, Nilüfer Aylin Acet Öztürk, Asli Gorek Dilektasli, Funda Coskun, Abdulmecid Yıldız, Mehmet Karadag

“…<h4>Conclusion</h4>The study demonstrates that PNI, age, and pulmonary function are critical factors influencing the survival of hemodialysis patients. …”
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The mediating role of anxiety and depression in the relationship between alexithymia, somatosensory amplification, and functional impairment in fibromyalgia by Arda Kazim Demirkan, Gizem Gerdan

“…Participants completed self-report measures assessing alexithymia, anxiety, depression, SSA, and functional impairment. Statistical analyses included independent samples t-tests and multivariate analyses of covariance (MANCOVA) to compare groups, and mediation analyses to examine indirect effects of anxiety and depression.ResultsThe FMS group reported significantly higher levels of anxiety, depression, DIF, and SSA compared to controls. …”
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MRI based radiomics nomogram for predict recurrence of non functioning pituitary macroadenomas post surgery by Ji-ping Zhao, Xue-jun Liu, Hao-zhi Lin, Chun-xiao Cui, Ying-jie Yue, Song Gao

“…Abstract Objective: To establish and validate a comprehensive predictive model combining clinical data and radiomics features to improve the accuracy of predicting recurrence within five years after surgery in patients with non-functioning pituitary macroadenomas (NFMA). Methods: This retrospective study included 292 NFMA patients who underwent surgery between January 2012 and January 2018, with an additional 123 patients as an external test set. …”
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Influence of physical loading on behavioral reactions of rats in cerebral hypoperfusion by V. V. Сhrishtop, T. A. Rumyantseva, V. G. Nikonorova, I. V. Fateev

“…Before the simulation, and at 6, 8, 14, 21, 28, 35, 60 and 90 days postoperatively, the animals were tested using a Morris water maze and an “open field” test. …”
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Assessment of Functional Capacity of Immune System in Patients with Multiple Sclerosis using QuantiFERON Monitor by Zbysek Pavelek, Ondrej Soucek, Jan Krejsek, Ilona Sejkorova, Oldrich Vysata, Blanka Klimová, Francesco Angelucci, Pavel Stourac, Martin Valis, Marek Peterka, Lukáš Sobisek, Michal Novotny

“…This result was also confirmed by a validation analysis to exclude impact of variable factors, such as disease duration and Expanded Disability Status Scale scores. …”
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