Applying the blended KTA-Sprint framework to a usability assessment of a digital health module for informal caregivers co-managing heart failure by Ting Xiong, Camila Benmessaoud, Kaylen J. Pfisterer, Noor El-Dassouki, Raima Lohani, Karen Young, Quynh Pham

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The influence of subjective well-being on anxiety, depression and quality of life in patients with functional dyspepsia by Guizhen Yong, Xi Wang, Yan Xu, Guobin He

“…Abstract Background Subjective well-being (SWB) encompasses both subjective happiness and objective factors. Anxiety and depression are increasingly recognized as contributing causes of functional dyspepsia (FD), yet the role of SWB in FD patients has been largely overlooked. …”
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Functional capacity, health impact, and risk of sarcopenia in individuals with chronic obstructive pulmonary disease. by Janine Bosi Tonel, Maitê Mendes Pellenz, Maria Elaine Trevisan, Ariovaldo Leal Fagundes, Luciane Flores Jacobi

“… This study aimed to verify the functional capacity of individuals with chronic obstructive pulmonary disease (COPD) and its associated factors. …”
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BRAIN NATRIURETIC PEPTIDE AS BIOCHEMICAL MARKER FOR STRUCTURAL AND FUNCTIONAL HEART DISORDERS IN ARTERIAL HYPERTENSION by S. V. Ivanova, Yu. A. Vasyuk, E. Yu. Shupenina, P. V. Krikunov, I. A. Sadulaeva

“…Assessment of structural and functional condition of the left and right heart chambers related to the level of NT-proBNP and clinical signs of CHD in AH patients.Material and methods. …”
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Validation of the Chinese version of Brief Assessment of Cognition in Schizophrenia by Wang LJ, Lin PY, Lee Y, Huang YC, Hsu ST, Hung CF, Chen CK, Chen YC, Wang YL, Tsai MC

“…Liang-Jen Wang,1 Pao-Yen Lin,2,3 Yu Lee,2 Yu-Chi Huang,2 Su-Ting Hsu,4 Chi-Fa Hung,2 Chih-Ken Chen,5,6 Yi-Chih Chen,5,6 Ya-Ling Wang,2 Ming-Che Tsai2 1Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 2Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 3Institute for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital, 4Department of Community Psychiatry, Kaohsiung Municipal Kai-Syuan Psychiatric Hospital, Kaohsiung, 5Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, 6Chang Gung University College of Medicine, Taoyuan, Taiwan, Republic of China Objective: A test battery that measures cognitive function impairment in patients with schizophrenia, the Brief Assessment of Cognition in Schizophrenia (BACS), has been translated into various languages and validated. …”
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Non-employment over the working life: Implications for cognitive function and decline in later life by A.J. Sizer, A. Sacker, R.E. Lacey, M. Richards

“…Objectives: Disuse theory predicts that cognitive function is vulnerable to transitions that remove factors that support cognitive skills. …”
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Effects of demographic characteristics on burnout, psychological resilience, and family functioning in parents of children with disabilities by Mehmet Salih Yildirim, Mustafa Özkan Firat, Mehmet Emin Atay, Dursun Alper Yilmaz, Gökhan Dege

“…Descriptive statistics, chi-square tests, and t-tests were used to analyze relationships between demographic factors, burnout, resilience, and family functionality. …”
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Anemia Is a Predictor of Withdrawal from Peritoneal Dialysis in Stable Peritoneal Dialysis Patients by Kenta Torigoe, Emiko Otsuka, Kiyokazu Tsuji, Ayuko Yamashita, Mineaki Kitamura, Takahiro Takazono, Noriho Sakamoto, Kumiko Muta, Hiroshi Mukae, Tomoya Nishino

“…The negative correlation between Hb levels and the annual decline in urine volume implies that anemia may contribute to PD withdrawal via the deterioration of residual renal function.…”
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Cognitive functions in schizophrenia: the interplay between blood viscosity, serum osmolarity, and symptom severity by Ipek Özönder Ünal, Miray Pirincci Aytac, Derya Adalı Aker, Tomris Duymaz, Tonguc Demir Berkol

“…Conclusion This study highlights the potential contribution of systemic physiological factors to cognitive function in schizophrenia. Higher WBV, within a physiological range, may support cerebral perfusion and be associated with better executive performance. …”
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Distinct risks of exacerbation and lung function decline between never-smokers and ever-smokers with COPD by Heemoon Park, Soo Min Jo, Kwang Nam Jin, Hyo Jin Lee, Hyun Woo Lee, Tae Yun Park, Eun Young Heo, Deog Kyeom Kim, Jung-Kyu Lee

“…Methods We retrospectively analyzed patients with COPD who underwent chest computed tomography and longitudinal lung function tests from January 2013 to December 2020. …”
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Stress Response of Aspergillus niger Spores to Copper Surfaces and the Implications for Antifungal Surface Functionalization by Stella Marie Timofeev, Katharina Siems, Daniel Wyn Müller, Aisha Saddiqa Ahmed, Alessa Schiele, Kristina Brix, Carolin Luisa Krämer, Franca Arndt, Ralf Kautenburger, Frank Mücklich, Stefan Leuko

“…Fungal spore viability assays show that 9 µm periodicities on copper surfaces achieve a 99% reduction in spore viability, indicating that increased copper ion release is a key factor in enhanced antifungal effectivity. Scanning electron microscopy (SEM) analysis confirm substantial spore damage, linked to the viability testing and the measured copper ion release by inductively coupled plasma triple quadrupole mass spectrometry (ICP‐QQQ) spectrometry. …”
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Effect of gut microbiome modulation on muscle function and cognition: the PROMOTe randomised controlled trial by Mary Ni Lochlainn, Ruth C. E. Bowyer, Janne Marie Moll, María Paz García, Samuel Wadge, Andrei-Florin Baleanu, Ayrun Nessa, Alyce Sheedy, Gulsah Akdag, Deborah Hart, Giulia Raffaele, Paul T. Seed, Caroline Murphy, Stephen D. R. Harridge, Ailsa A. Welch, Carolyn Greig, Kevin Whelan, Claire J. Steves

“…Outcomes are physical function and cognition. The trial is carried out remotely using video visits, online questionnaires and cognitive testing, and posting of equipment and biological samples. …”
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Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. by Chisom Soremekun, Tafadzwa Machipisa, Opeyemi Soremekun, Fraser Pirie, Nashiru Oyekanmi, Ayesha A Motala, Tinashe Chikowore, Segun Fatumo

“…<h4>Background</h4>Liver disease is any condition that causes liver damage and inflammation and may likely affect the function of the liver. Vital biochemical screening tools that can be used to evaluate the health of the liver and help diagnose, prevent, monitor, and control the development of liver disease are known as liver function tests (LFT). …”
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Functional Capacity and Inflammatory Mediators in Elderly Residents of Counties with Different Human Development Index by Lygia P. Lustosa, Daniele R. Xavier, Giane A. Ribeiro-Samora, Daniele S. Pereira, Adriana N. Parentoni, Ronaldo L. Thomasini, Leani S. M. Pereira

“…A number of studies have indicated that certain factors, including socioeconomic status and education, are associated with the functional health status of the elderly. …”
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Association of serum klotho with cognitive function among individuals with nonalcoholic fatty liver disease by Feilong Wu, Jie Pan, Mingtao Chen, Xuye Lai, Yingying Gu, Lei Pei, Lili Yang

“…Weighted logistic regression and restricted cubic splines were employed to analyze the relationship between klotho levels and cognitive scores.ResultsA significant nonlinear association was observed between klotho levels and the performance in DSST and Delayed Recall Test (DRT). After controlling for confounding factors, the study found a positive association between higher serum klotho levels and improved cognitive performance in both AFT and DSST. …”
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Stroke ICF Core Element Scale and Stroke Common Functional Scale: Association Studies by Qiao JIN, Xiaoyan YANG, Qijing REN

“…Objective:To investigate the correlation between Stroke ICF Core Element Scale and Stroke Common Functional Scale.Methods:Using Stroke ICF Core Element Scale, Fugl-Meyer Scale, Modified Barthel Index (MBI) to assess 50 cases of stroke patients, performing the correlation test with <italic>Pearson</italic> coefficient, <italic>Kappa</italic> value and <italic>Cronbach</italic> alpha coefficient to evaluate the validity, reliability and content consistency of the ICF Scale.Results:The <italic>Kappa</italic> values were between 0.676-0.958 (<italic>P</italic>&lt;0.001), with a good test-retest reliability and inter-rater reliability, the evaluation outcomes of two raters had a better consistency; <italic>Cronbach</italic> alpha coefficient had a good consistency in body functions, activities, participation and the environmental factors. …”
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Objective and subjective assessment of back shape and function in persons with and without low back pain by N. Taheri, L. Becker, L. Fleig, F. Schömig, B. U. Hoehl, L. M. S. Cordes, U. Grittner, L. Mödl, H. Schmidt, M. Pumberger

“…Participants with back pain lasting for 12 weeks or more were categorized as cLBP patients, while participants with back pain for less than 12 weeks were classified as non-chronic LBP patients (ncLBP). Back function was quantified using finger-to-floor distance (FFD), Ott and Schober test, and 30 s sit-to-stand test (STS). …”
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A new Drosophila model of prolonged inactivity shortens lifespan and impairs muscle function by Jodi Protasiewicz, Sarah Snider, Mousumee Khan, Li Tao, Robert J. Wessells, Alyson Sujkowski

“…Here, we developed a Drosophila model of confinement inactivity (CI) to observe its effects on lifespan and muscle function. We found that, similar to mammalian models and humans, CI negatively impacted longevity and function in Drosophila. …”
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A Cross-Sectional Study on Functional Disability among the Elderly in Rural Area of Goa by Arya Ravi, Vanita G. Pinto Da Silva

“…To determine the factors associated with functional disability among study participants Methods: A community-based cross-sectional study was conducted among elderly individuals (aged 60 years and above) in the field practice area of Rural Health and Training Centre, Mandur, Goa. …”
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Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease. by Maria Sabater-Lleal, Anders Mälarstig, Lasse Folkersen, María Soler Artigas, Damiano Baldassarre, Maryam Kavousi, Peter Almgren, Fabrizio Veglia, Guy Brusselle, Albert Hofman, Gunnar Engström, Oscar H Franco, Olle Melander, Gabrielle Paulsson-Berne, Hugh Watkins, Per Eriksson, Steve E Humphries, Elena Tremoli, Ulf de Faire, Martin D Tobin, Anders Hamsten

“…To identify potential common pathways across the two diseases, we tested all recently published single nucleotide polymorphisms (SNPs) associated with human lung function (spirometry) for association with carotid intima-media thickness (cIMT) in 3,378 subjects with multiple CAD risk factors, and for association with CAD in a case-control study of 5,775 CAD cases and 7,265 controls. …”
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