Estimation of the effect of lithium salts on cytokine production by blood cells in in vitro experiments by T. R. Vetlugina, E. V. Epimakhova, D. N. Savochkina, E. V. Plotnikov, A. S. Boiko, S. A. Ivanova, N. A. Bokhan

“…In parallel, control samples without lithium salts were tested; the samples were incubated for a day. The concentration of cytokines (interferon (IFN) γ, interleukin (IL)-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-17A, tumor necrosis factor (TNF) α) was determined in the culture supernatants on the MAGPIX multiplex analyzer (Luminex, USA) (Center for Collective Use “Medical Genomics”, Tomsk NRMC) using the Human Cytokine / Chemokine Magnetic Bead Panel (Merck, Germany).Results. …”
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Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection by Thomas J. Waller, Catherine A. Collins, Monica Dus

“…Synaptic and axonal degeneration were measured through immunohistochemistry, microscopy, and blinded scoring of fly larvae at both early and later 3rd instar stages to test for progressive phenotypes. Nervous system injury through a physical nerve crush assay was used to assay functional outcomes of protective stress responses. …”
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Impaired central sensitivity to thyroid hormone is associated with hypertriglyceridemia in euthyroid population by Yu Gong, Yu Gong, Guojuan Wang, Qianqian Zhang, Xu Jiang, Zhangxiang Zhu, Ying Li

“…Biochemical parameters including thyroid hormones (THs), liver and kidney functions, blood glucose, and blood lipids were measured. …”
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A Study on the Preparation of Multifunctional <i>Bacillus</i> spp. Composite Inoculants and Their Ability to Promote Watermelon Growth by Lin Li, Ke Liu, Fafa Lan, Wentao Xiao, Baoping Wang, Jing Zhou, Jitao Zhang, Yunjie Wen, Xiuhong Wang, Xiangyuan Shi

“…The optimal media were peptone (15 g/L), sucrose (10 g/L), and KCl (2 g/L); the optimal incubation conditions were an initial pH of 7.0, a volume of 47 mL/250 mL, an inoculum size of 6% <i>v</i>/<i>v</i>, an incubation temperature of 31 °C, a shaking speed of 205 r/min, and an incubation period of 20 h, as determined through a single factor test and the response surface methodology (RSM). …”
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Markers of Inflammation and Hypofibrinolysis Are Associated with Cognitive Dysfunction and Motor Performances in Atrial Fibrillation Patients on Oral Anticoagulant Therapy: Insight... by Francesco Alfano, Francesca Cesari, Anna Maria Gori, Martina Berteotti, Emilia Salvadori, Betti Giusti, Alessia Bertelli, Filippo Fratini, Angela Rogolino, Benedetta Formelli, Francesca Pescini, Enrico Fainardi, Eleonora Barucci, Giulia Salti, Arianna Cavaliere, Andrea Ginestroni, Rossella Marcucci, Anna Poggesi

“…Results refer to 180 subjects who underwent a complete clinical, biohumoral, cognitive, and functional evaluation. <b>Results:</b> At multivariate logistic regression, Clot Lysis Time (CLT) and circulating levels of von Willebrand Factor (vWF) remained significantly associated with pathological performances at the Stroop test (expressed as execution time) [OR 95% CI 1.54 (1.02–2.35), <i>p</i> = 0.042 and 1.75 (1.08–2.82), <i>p</i> = 0.023, respectively]. …”
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Efficacy and Safety Assessment of a Dietary Supplement in a Rat Model of Osteoarthritis and Dogs with Arthritic Signs by Geon A Kim, Mi-Jin Lee, Eun Pyo Kim, Gun Ho Heo, Seung Gyu Oh, Se Chang Park, Byeong Chun Lee, Sang O Park

“…BJH administration before OA induction significantly decreased OA severity and functional recovery. Consuming a BJH supplement showed modifying and chondroprotective effects and significantly reduced cartilage degeneration and inflammation with no side effects. …”
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Effectiveness of a Virtual Reality Serious Video Game (The Secret Trail of Moon) for Emotional Regulation in Children With Attention-Deficit/Hyperactivity Disorder: Randomized Clin... by Marina Martin-Moratinos, Marcos Bella-Fernández, María Rodrigo-Yanguas, Carlos González-Tardón, Chao Li, Ping Wang, Ana Royuela, Pilar Lopez-Garcia, Hilario Blasco-Fontecilla

“…Analysis was conducted using the Student 2-tailed t test and 2-factor ANOVA. An independent monitor supervised the study. …”
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ROLE OF SERUM EOSINOPHILIC CATIONIC PROTEIN AND TRYPTASE IN MYELOPROLIFERATIVE AND LYMPHOPROLIFERATIVE DISORDERS by L. S. Komarova, N. B. Mikhaylova, I. I. Nesterovich, Ye. Ye. Zueva, B. V. Afanasyev, Areg A. Totolian

“…Therapeutic interventions into key events controlling eosinophil migration may be a leading factor in treatment of hypereosinophylic states in onco-hematological disorders. …”
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ALDOC promotes neuroblastoma progression and modulates sensitivity to chemotherapy drugs by enhancing aerobic glycolysis by Yunpeng Chen, Haixia Zhu, Yishu Luo, Tianyue Xie, Youyang Hu, Zhiwei Yan, Weichao Ji, YaXuan Wang, Qiyou Yin, Hua Xian

“…Functional experiments, including proliferation and migration assays, were conducted in ALDOC-interfered NB cell lines. …”
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The impact of health care financing on the economic growth: EU countries analysis by Anastasiia Samoilikova, Rosen Kunev

“…The key aim of the research is to investigate the dynamics of health care financing as a factor of economic growth based on EU countries analysis. …”
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Airway epithelial cell-specific deletion of EGFR modulates mucoinflammatory features of cystic fibrosis-like lung disease in mice by Ishita Choudhary, Kshitiz Paudel, Rahul Kumar, Amit Sharma, Sonika Patial, Yogesh Saini

“…Therefore, we hypothesized that airway epithelial cell-specific deficiency of EGFR mitigates mucoinflammatory responses in Scnn1b-transgenic (Tg+) mice that phenocopy human CF-like lung disease. To test this hypothesis, we examined the effect of airway epithelial cell-specific EGFR deficiency on the manifestation of mucoinflammatory outcomes in Tg+ mice. …”
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The impact of urbanization on land use land cover change using geographic information system and remote sensing: a case of Mizan Aman City Southwest Ethiopia by Addis Bikis, Muluye Engdaw, Digvijay Pandey, Binay Kumar Pandey

“…Preprocessing, classification of the images and accuracy assessment were tested separately using the kappa coefficient. The analysis incorporates factor graph optimization for ambiguity resolution. …”
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Prognostic value of lymphocyte-to-monocyte ratio in patients with endometrial cancer: an updated systematic review and meta-analysis by Zijing Huang, Donghua Yang, Congrong Liu

“…Biological mechanisms linking inflammation and cancer support the role of LMR in prognosis, given the functions of lymphocytes and monocytes in tumor progression and immune response. …”
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FLI1 Induces Plaque Psoriasis and Its Inhibition Attenuates Disease Progression by Hu M, Yu K, Wang C, Liu W, Hu A, Kuang Y, Gajendran B, Zacksenhaus E, Sartori G, Bertoni F, Xiao X, Ben-David Y

“…Inhibitors such as chelerythrine (CLT) were tested for their suppressive effects on these genes. …”
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Anxiety-depressive disorders in patients with coronary artery disease with borderline coronary artery stenosis and visceral obesity by D. A. Yakhontov, Yu. O. Ostanina, O. V. Dunicheva, T. G. Tsibina, N. A. Kokoulina, V. L. Lukinov

“…The first group consisted of patients with stable borderline CAD with increased epicardial fat thickness (EFT) — 57 (28,4%) people, the second group — patients without increased EFT — 144 (71,6%) people. Blood biochemical tests, levels of inflammatory markers (high-sensitivity C-reactive protein, interleukin (IL)-1, IL-6, IL-8, IL-10, tumor necrosis factor alpha, N-terminal pro-brain natriuretic peptide) were assessed. …”
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Clinical Efficacy and Safety of the Herbal Prescription, HH333, in Preventing Recurrent Stroke in Patients With Ischemic Stroke Induced by Small-Vessel Disease: Protocol for Multic... by Han-Gyul Lee, Seungwon Kwon, Woo-Sang Jung, Sang-Kwan Moon, Cheol-Hyun Kim, Dong-Jun Choi

“… BackgroundPatients with ischemic stroke are at high risk of recurrence, making preventive care an important factor. Current antiplatelet therapy for recurrence prevention treatment has several limitations. …”
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CircRNA-miRNA-mRNA regulatory network in high-altitude hypobaric hypoxia-induced hearing impairment and hearing acclimatization by Danzeng Awang, Kanzi Danzeng, Tianheng Wang, Quzong Deji, Mengting Huang, Hailong Ren, Xinzhu Liu, Binghan Zhao, Lanzi Gongga

“…The DEmRNAs in this network were functionally annotated using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses based on Metascape. …”
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Identification of ZNF652 as a Diagnostic and Therapeutic Target in Osteoarthritis Using Machine Learning by Chen Y, Liang R, Zheng X, Fang D, Lu WW, Chen Y

“…Zinc Finger Protein 652 (ZNF652) is a transcription factor implicated in various biological processes. …”
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Development of an iridium complex fluorescent probe for FGF21 protein labeling and tracking by Lili Zhang, Shaobo Du, Wangye Ji, Jianfei Li, Ruilin Ma, Dexiang Yan, Yuhao Niu, Shuqin Zhao, Jiaxi Ru, Yuan Gao

“…In this study, a non-emissive cyclometalated Ir(III) solvent complex IrCN was synthesized for FGF21 protein labeling. Binding test showed that the optimal binding ratio of IrCN and FGF21 protein was 1:100 (W/W). …”
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Measuring attitudes towards ethnic minority patients: the revalidated REMP-3 instrument for graduate healthcare practitioners by Stijn Schelfhout, Robin Vandecasteele, Sara Willems, Eva Derous, Stéphanie De Maesschalck

“…As theoretically predicted, the REMP-3 also functions as a measure of intercultural attitudes in an intercultural competence framework. …”
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