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ASSESSMENT OF THE N-TERMINAL COLLAGEN III-TYPE PROPEPTIDE IN PATIENTS WITH CHRONIC HEART FAILURE AND METABOLIC SYNDROME
Published 2015-12-01“…The severity of clinical manifestation of CHF was evaluated, and patients functioning status. All patients underwent clinical and biochemical blood tests, electrocardiography. …”
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5342
Nanoparticles from grape seed extract inhibit inflammatory cytokines and ameliorate CCl4-induced hepatotoxicity
Published 2025-07-01“…Conversely, GS extract NPs supplementation potentially ameliorate hepatic functions by normalization of serum ALT, AST and ALP, reduced MDA level, improved antioxidant CAT, regulated liver inflammatory cytokines via maximal reduction of hepatic IL-1β, IL-4, IL-6 and TNF-α. …”
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5343
"Preparation and curing kinetics of “bottlebrush-like structure” green bio-based ultra-low-temperature polyfarnesene nanocomposites"
Published 2024-12-01“…In this work, hydroxyl-terminated polyfarnesene (HTPF) was synthesized by free-radical solution polymerization, and enhanced HTPF-based polyurethane elastomers (HTPF-PU) was prepared using HTPF as soft segment and functionalized graphene oxide (GO) modified with isophorone diisocyanate (IPDI) as functional filler by one-step process for the first time, which allowed the isocyanate groups on modified graphene oxide (iGO) and the hydroxyl groups in HTPF to form covalent bonds to prepare nanocomposites with a strong interfacial bonding effect, as shown in Fig 1. …”
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Correlation Between Electronic Patient-Reported Outcomes and Biological Markers of Key Parameters in Acute Radiation Cystitis Among Patients With Prostate Cancer (RABBIO): Prospect...
Published 2024-12-01“…An increase in serum and urine levels of macrophage colony-stimulating factor (M-CSF), hepatocyte growth factor, and macrophagic inflammatory protein was observed at week 12 compared to baseline levels. …”
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5346
RETRACTED ARTICLE: Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-β1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-α-induced NF-κB/Sna...
Published 2014-11-01“…Moreover, the activation of nuclear factor κB (NF-κB)/Snail signaling pathway induced by tumor necrosis factor-α (TNF-α) was also attenuated under the pretreatment of COE. …”
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5347
Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides
Published 2025-02-01“…Objectives: In this study, the lipopolysaccharide-binding domain (LBD) was identified through machine learning-guided directed evolution, which acts as a functional domain of the anti-lipopolysaccharide factor family of AMPs identified from Marsupenaeus japonicus. …”
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5348
The association between vitamin D level and periodontal disease in Saudi population, a preliminary study
Published 2021-11-01“…Objective: Among other regulatory functions, vitamin D has a role in modulating the inflammatory process of periodontal disease. …”
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5349
Exploring the Relationship Between Childhood Maltreatment, Alexithymia, and Facial Emotional Recognition in Schizophrenia
Published 2025-08-01“…ABSTRACT Background: Childhood maltreatment is a significant factor affecting social cognition in schizophrenia (SCZ) patients. …”
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5350
Integrating behavioral and neurophysiological insights: High trait anxiety enhances observational fear learning
Published 2025-02-01“…Neuroimaging data, derived via functional near-infrared spectroscopy (fNIRS) revealed heightened medial prefrontal cortex activation in HTA participants when directly facing threats. …”
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5351
Genome-wide identification of lipid transfer proteins in Sorghum bicolor and discovery of flower-specific promoters
Published 2025-07-01“…Their promoters were functionally tested in transgenic Arabidopsis thaliana, revealing distinct spatial and stress-responsive expression profiles. …”
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5352
The impact of early life experiences on inhibitory control and working memory
Published 2024-11-01“…Dramatic environmental events during this period, such as history of institutionalisation, can disrupt optimal developmental pathways, leaving biological scars for life.MethodsThe focus of this study was to investigate the impact of institutionalisation on the development of inhibitory control and working memory in three groups of children matched for age (n = 130; 7.1 ± 2.0 years): (1) early institutionalised (n = 35; age of placement: 6.9 ± 10.6 months; duration of placement: 14.6 ± 10.4 months); (2) late institutionalised (n = 29; age of placement: 49.3 ± 30.6 months; the duration of placement: 16.0 ± 19.4 months); (3) never institutionalised (n = 66).ResultsResults showed that the early institutionalised group had the lowest scores on tests of inhibitory control (p = 0.03), working memory (p = 0.03) and retrieval-based learning (p = 0.04), while the results of the group of late institutionalised children do not differ significantly from never institutionalised.DiscussionThe existence of a sensitive period during the first 18 months of a child’s life is discussed, which determines the formation of the retrieval-based learning mechanism and of inhibiting ineffective experience, for which executive functions are responsible.…”
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5353
Evaluation of Regeneration Effects of Different Rejuvenators on Aged Asphalt
Published 2025-04-01“…Regeneration technology is the main approach to achieve its recycling; therefore, the rejuvenator is an important factor affecting the regeneration effect. In order to evaluate the rejuvenation effects of rejuvenators on aged asphalt, fluid catalytic cracking (FCC) slurry and a penetrant containing epoxy functional groups were used to prepare conventional rejuvenators (CR1 and CR2) and a penetrable rejuvenator (PR). …”
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5354
The Role of Anti-Interferon-α Autoantibodies in Severe COVID-19: Implications for Vaccination Prioritization
Published 2025-07-01“…<b>Conclusions</b>: Elevated and functionally neutralizing anti-IFN-α AAbs were associated with severe COVID-19. …”
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5355
Silence of a dependence receptor CSF1R in colorectal cancer cells activates tumor-associated macrophages
Published 2022-12-01“…However, we found here that the CSF1R expression was abnormally down-regulated in colorectal cancer (CRC), and its biological functions and underlying mechanisms have become elusive in CRC progression.Methods The expression of class III receptor tyrosine kinases in CRC and normal intestinal mucosa was accessed using The Cancer Genome Atlas and Gene Expression Omnibus datasets and was further validated by our tested cohort. …”
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BLOOD PRESSURE VARIABILITY AND THE CONDITION OF TARGET ORGANS IN MENOPAUSAL WOMEN
Published 2014-06-01“…Increased variability of arterial pressure among menopausal women can be considered as additional factor of target organ damage in early stages of climacteric.…”
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Optimizing energy efficiency in residential buildings: A comprehensive evaluation of solar concrete water heaters integrated with photovoltaics and thermoelectric cooling
Published 2025-08-01“…This study presents a Solar Concrete Water Heater (SCWH) integrating solar water heating, photovoltaic (PV) power generation, and thermoelectric generator (TEG) cooling, functioning as a structural roof component. The system was tested in three stages: Phase One evaluated Copper (C)- and Galvanized Iron (GI)-SCWHs, Phase Two integrated PV panels, and Phase Three added TEGs for cooling and additional power generation. …”
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SLPDBO-BP: an efficient valuation model for data asset value
Published 2025-04-01“…Secondly, in an attempt to comprehensively evaluate the optimization performance of SLPDBO, a series of numerical optimization experiments are carried out with 20 test functions and with popular optimization algorithms and dung beetle optimizer (DBO) algorithms with different improvement strategies. …”
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Comparison of different graft materials on the proliferation, mineralization and mineralized tissue-related gene expressions of cementoblasts
Published 2025-03-01“…In conclusion, released components of all graft materials have positive effects on the cementoblast’s functions while Bio-Oss® might be preferable for gene expressions. …”
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Rifampicin Repurposing Reveals Anti-Melanogenic Activity in B16F10 Melanoma Cells
Published 2025-02-01“…Applying this approach to the development of cosmeceutical ingredients enables the creation of functional compounds with proven safety and efficacy, adding significant value to the cosmetic industry. …”
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