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4981
Validating an IoT implementation framework for supporting industry 4.0 in SMEs: a Delphi and focus group approach
Published 2025-05-01“…Despite recognizing the framework's comprehensiveness, experts highlighted the need for improved functionality and real-time performance, while expressing concerns about complexity. …”
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4982
Quantifying the burden of hereditary hemorrhagic telangiectasia on quality of life and psychological health: a cross-sectional study
Published 2025-03-01“…Participants expressed a substantial effect on their physical (143/560 [25%]), role (140/556 [25%]), emotional (124/554 [22%]), social (104/556 [18%]), and cognitive (64/550 [11%]) functioning. However, more participants considered extremely important to improve their physical (289/560 [51%]), cognitive (266/550 [47%]), role (253/556 [43%]), emotional (243/554 [45%]), and social (233/556 [41%]) functioning affected by HHT. …”
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4983
Association between daily living activities and quality of life in post-COVID-19 patients: a cross-sectional study
Published 2025-06-01“…After the acute period of COVID-19, many people still face considerable difficulties in carrying out activities of daily living (ADLs), which are essential for independent functioning and overall quality of life (QoL). Objective This study aimed to prompt how these persistent symptoms affect individuals’ ability to perform ADLs-basic tasks essential for self-care and daily functioning and how these limitations, in turn, influence overall QoL. …”
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4984
Causal relationships between four types of lipids and breast cancer risk with potential mediators: evidence from Mendelian randomization study and bioinformatics analysis
Published 2025-05-01“…Abstract Background and purpose Breast cancer (BC) is the primary cause of cancer-related deaths among women worldwide, with increasing evidence pointing to the effect of metabolic factors, particularly lipid levels, in its pathogenesis. …”
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4985
Prognostic Significance of Elevated Platelet Count (>200 x 10^9 per L) in BCLC Stages B and C of Hepatocellular Carcinoma: A Retrospective Multicenter Analysis
Published 2025-05-01“…Various platelet count cutoffs (X to Y × 10^9/L) were tested to identify the optimal prognostic threshold. …”
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4986
Bioremediation of malachite green dye using Sargassum wightii seaweed and its biological and physicochemical characterization
Published 2025-04-01“…FTIR interpretation revealed that the treated water reduces the dye concentration in water, which is evident through reduction of functional groups when compared with FTIR results of untreated water. …”
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4987
Application of indigenous Saccharomycopsis fibuligera for light-flavor Baijiu fermentation: Changes of microbial community and flavor metabolism
Published 2025-01-01“…(the main fungal biomarkers), which was driven by the functional S. fibuligera. Mantel test further highlighted acidity, temperature, and moisture as critical environmental factors influencing the microbial community (P < 0.05, |ρ| > 0.7). …”
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4988
Arabic validation and cross-cultural adaptation of climate anxiety scale
Published 2024-11-01“…Model reliability coefficient omega (omega/omega S) for general factor, functional domain, and cognitive domain were 0.94, 0.92, and 0.89, respectively, suggesting a satisfactory fit threshold. …”
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4989
Virtual reality solution to promote adapted physical activity in older adults: outcomes from VR2Care project exploratory study
Published 2025-05-01“…BackgroundInsufficient physical activity is one of the leading risk factors for death worldwide. Regular exercise can improve physical performance and quality of life, reduce the risks of falls and depressive symptoms, and reduce the likelihood of cognitive decline in older adults. …”
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4990
The 3′ region of the ZPA regulatory sequence (ZRS) is required for activity and contains a critical E-box
Published 2025-07-01“…We hypothesized that the central E-box was required for activity, while the other E-boxes and Hoxd13 sites localize ZRS activity to the distal posterior limb mesoderm.MethodsTo identify the functional role of each subdomain, we generated three ZRS fragments (5′, central, and 3′) and combined fragment constructs to test subdomain collective contributions. …”
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4991
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4992
Microglial CD2AP deficiency exerts protection in an Alzheimer’s disease model of amyloidosis
Published 2024-12-01“…Single nucleotide polymorphisms (SNPs) in the CD2AP gene have been associated with Alzheimer’s disease (AD). However, the functional role of CD2AP, especially its role in microglia during AD onset, remains elusive. …”
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4993
AI-driven pharmacovigilance: Enhancing adverse drug reaction detection with deep learning and NLP
Published 2025-12-01“…BERT and GPT, were also employed to provide the functionality of textual interactions over medical data. • Performance metrics such as accuracy, precision, recall, and F1-score were systematically applied to evaluate each model’s performance. …”
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4994
Postgraduate Clinical Residency: The Impact of Multiple-Choice Question Quality on Exam Success Rates
Published 2025-08-01“…Other potentially influential factors require further multivariate analytical research. …”
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4995
Multidimensional analysis of sedentary behaviour and participation in Spanish stroke survivors (Part&Sed-Stroke): a protocol for a longitudinal multicentre study
Published 2023-02-01“…Introduction Stroke survivors usually experience long-lasting functional, emotional and social consequences that might contribute to sedentary behaviour and participation restrictions, which are important targets to address during rehabilitation. …”
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4996
The Assessment of Utility and the Role of Rural Entrepreneurship Ecosystem in West Azerbaijan Province
Published 2017-08-01“…In the first step, one-sample T-test in SPSS software is applied to analyze the questionnaires. …”
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4997
Multi-omics unveils BCAA metabolism markers L-leucine and HMGCS1 as prognostic marker for immunotherapy efficacy in non-small cell lung cancer
Published 2025-06-01“…Methods Plasma metabolites were measured using untargeted UPLC-MS/MS (n = 94 and 40), with lymphocyte subset tests on 72 patients. BCAA-related subtypes were identified in NSCLC datasets (n = 274, 176, and 196). …”
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4998
ASSESSMENT OF IMPACT OF ORAL HEALTH PARAMETERS ON ORAL HEALTH-RELATED QUALITY OF LIFE IN FUTURE DENTISTS
Published 2020-06-01“…There were seven dimensions of negative impact on OHRQoL: functional limitation, physical pain, psychological discomfort, physical disability, psychological disability, social disability, and handicap. …”
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4999
Predictors of probable sarcopenia and sarcopenia in older adults under outpatient geriatric care
Published 2025-06-01“…This study investigated predictive factors for probable sarcopenia and sarcopenia in older adults in outpatient care. …”
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5000
Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review
Published 2025-05-01“…The search covered evidence from 1 January 2001 up to 21 July 2021 and yielded 16,775 hits, which were then reduced to 14,383, after using EndNote X9’s (2013) inbuilt duplication detection function and manual de-duplication. Results were imported to Covidence. …”
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