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4501
Employment of Regression-Based Decision Tools to Predict the Shear Capacity of Reinforced Concrete Beams Without Web Reinforcement
Published 2025-07-01“…Other key factors included the beam width, effective depth, reinforcement area, concrete compressive strength, and the shear span-to-depth ratio. …”
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4502
State ownership and firm performance: A performance evaluation of disinvested public sector enterprises
Published 2021-12-01“…Further, the paper intends to study the other firm factors that influence the performance parameters. …”
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4503
Genetic and Molecular Characterization of Atopic Eczema: A Comprehensive Bioinformatics Analysis of Gene Interactions and Pathways
Published 2025-04-01“…Genes including interleukin (IL) 10, transforming growth factor-β1 (TGFB1), tumor necrosis factor (TNF), and IL4 emerged as central nodes within multiple interacting networks, underscoring their potential roles in mediating disease processes. …”
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4504
Do wild ungulates utilize at-grade fauna passages as effectively as fauna overpasses or underpasses?
Published 2025-03-01“…However, at-grade passages have besides risk for vehicle collision involvement, a higher disturbance potential, compared to most over- and underpasses, considering foremost its multiuse with vehicle traffic. We tested if the crossing probability in common Scandinavian ungulates; wildboar (Sus scrofa), roedeer (Capreolus capreolus) and fallow deer (Dama dama), was impacted due to different types of crossing structure, while accounting for availability to alternative crossing sites and environmental factors. …”
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4505
Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence.
Published 2009-08-01“…Analysis of polymorphism and divergence in the non-coding portion of the human genome yields crucial information about factors driving the evolution of gene regulation. …”
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4506
Depression among Elderly - An Unaddressed Emerging Burden. A Community Based Cross Sectional Study
Published 2019-12-01“…Depression can cause great suffering and impaired functioning in daily life. Aim: study are to find the prevalence and factors influencing depression among rural elderly study partici-pants. …”
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4507
Content Analysis of Judges’ Sentiments Toward Artificial Intelligence Risk Assessment Tools
Published 2024-03-01“…Objective: to analyze the positions of judges on risk assessment tools using artificial intelligence.Methods: dialectical approach to cognition of social phenomena, allowing to analyze them in historical development and functioning in the context of the totality of objective and subjective factors, which predetermined the following research methods: formal-logical and sociological.Results: Artificial intelligence (AI) uses computer programming to make predictions (e.g., bail decisions) and has the potential to benefit the justice system (e.g., save time and reduce bias). …”
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4508
The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse.
Published 2014-01-01“…While Shh(+/-) and Gli2(+/-) mice have been described as phenotypically normal, these results illustrate a functional haploinsufficiency of both genes in combination with ethanol exposure. …”
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4509
Antidepressant effects and mechanisms of Wuhua herbal tea in a rat model of chronic unpredictable mild stress
Published 2025-07-01“…It also restores BDNF-CREB pathway function, reducing depressive symptoms.…”
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4510
Alfacalcidol in clinical practice: focus on the efficacy and safety of the Russian generic drug
Published 2024-04-01“…The most important factors that determine the risk of fractures are not only the presence of osteoporosis (OP), but also the risk of falls. …”
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4511
Severe Hypoglycemia and Pituitary Stalk Interruption Syndrome in a 5-Year-Old Boy with Coexistent Hyperprolinaemia: A Case Report and Literature Review
Published 2025-05-01“…Hormone profiling revealed lower-than-expected insulin-like growth factor-1 (IGF-1) concentrations, prompting a GH stimulation test, which, in turn, revealed GHD. …”
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4512
Rational design of FVIII sialylated peptides to target Siglec-3 and Siglec-9 and improve peptide formulations for reverse vaccines
Published 2025-04-01“…Reverse vaccine formulations have shown their potential for the treatment of allergies and other autoimmune diseases by the design of antigens that modify dendritic cell function towards tolerogenic responses. We here demonstrate that modification of an immunodominant peptide from factor VIII (FVIII) with a tolerizing molecule, sialic acid, improves existing peptide formulations towards the induction of tolerogenic cytokine secretion by DCs. …”
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4513
Influence law of abnormal coal thickness zone on coal and gas outburst
Published 2025-06-01“…The abnormal area of coal thickness is an important factor affecting the occurrence of coal and gas outburst. …”
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4514
Mangiferin mitigates dexamethasone-induced insulin resistance in rats: insight into vascular dysfunction and hepatic steatosis
Published 2025-05-01“…Additionally, Mang attenuated DEX-induced alterations in liver function parameters and improved serum lipid profiles, oxidative stress, and antioxidant biomarkers. …”
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4515
Aegeline improves doxorubicin-induced liver toxicity by modulating oxidative stress and Bax/Bcl2/caspase/NF-κB signaling
Published 2025-07-01“…Administration of aegeline at both tested doses led to a significant (P < 0.05) reduction in liver enzyme levels such as ALT, ALP, and AST—in rats with DOX-induced hepatotoxicity, indicating improved liver function. …”
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4516
Comparison of Malondialdehyde, Acetylcholinesterase, and Apoptosis-Related Markers in the Cortex and Hippocampus of Cognitively Dysfunctional Mice Induced by Scopolamine
Published 2024-10-01“…And this study evaluates the differences in cognitive function and the expression of malondialdehyde (MDA), acetylcholinesterase (AChE), and brain-derived neurotrophic factor (BDNF) in mice’s hippocampi and cortexes based on scopolamine dosages. …”
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4517
A role for TRPC3 in mammalian testis development
Published 2024-02-01“…In summary, our study suggests that SOX9 positively regulates Trpc3 in mouse testes and TRPC3 may mediate SOX9 function during Sertoli, germ and endothelial cell development.…”
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4518
Dietary Choline Deprivation Exacerbates Kidney Injury in Streptozotocin-Induced Diabetes in Adult Rats
Published 2025-01-01“…Rats were euthanized at week 5 of the study. Biochemical tests, renal histopathology, immunohistochemistry of the kidney injury molecule-1 (KIM-1), and vascular endothelial growth factor-A (VEGF-A) expression were assessed. …”
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4519
Visual impairment in any eye adversely affects quality of life: Psychometric validation of the Malay NEI VFQ-25.
Published 2025-01-01“…Psychometric analysis was performed including test-retest and internal consistency reliability, convergent validity, discriminant validity, and factor analysis. …”
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4520
Methods to assess lower limb prosthetic adaptation: a systematic review
Published 2025-04-01“…The predominant methods for assessing lower-limb prosthetic fitting include mobility evaluation, gait analysis, measurement of physical variables, and stability assessment. Functional tests and self-report questionnaires, which do not require specialized equipment or great expertise, are the most widely utilized techniques. …”
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