Fatigue outcomes following COVID-19: a systematic review and meta-analysis by Rachael A Evans, Trudie Chalder, Fiona Gaughran, Kim Poole-Wright, Ismail Guennouni, Olivia Sterry

“…Heterogeneity was assessed using Cochran’s Q and I2 statistic. Egger’s tests for publication bias.Results Database searches returned 14 262 records. …”
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Neuropsychological and clinical variables associated with cognitive trajectories in patients with Alzheimer's disease by Marianna Riello, Monica Moroni, Stefano Bovo, Flavio Ragni, Manuela Buganza, Raffaella Di Giacopo, Marco Chierici, Lorenzo Gios, Matteo Pardini, Matteo Pardini, Federico Massa, Federico Massa, Monica Dallabona, Elisa Vanzetta, Cristina Campi, Cristina Campi, Michele Piana, Michele Piana, Sara Garbarino, Manuela Marenco, Venet Osmani, Giuseppe Jurman, Antonio Uccelli, Antonio Uccelli, Bruno Giometto, Bruno Giometto, NeuroArtP3 Network, Filippo Gerli, Guido Pasquini, Claudia Niccolai, Matteo Betti, Emilio Portaccio, Maria Pia Amato, Rossi Andrea, Parodi Costanza, Ramaglia Antonia, Tortora Domenico, Severino Mariasavina, Andrea Falini, Antonella Castellano, Nicolò Pecco, Paola Scifo, Sonia Calloni

“…Also, our study used the results of single cognitive tests as a measure of specific cognitive functions allowing for a finer-grained analysis of risk factors with respect to the other studies that have principally used aggregated scores obtained by short neuropsychological batteries. …”
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Microstructure and resultant properties of ex-situ Alloy 625+TiB2 nanocomposites processed via suction casting as filler material for Ni-based superalloys repair applications by Łukasz Rakoczy, Małgorzata Grudzień-Rakoczy, Grzegorz Cempura, Tomasz Kargul, Ewa Rząd, Marcin Madej, Tomasz Dudziak, Dawid Kozień, Rafał Cygan, Adrian Graboś, Dušan Galusek

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METHODS FOR CELLULAR AND MOLECULAR COMPOUND OF ATHEROSCLEROTIC PLAQUES ASSESSMENT: LITERARY REVIEW by Yu. V. Saranchina, O. Yu. Kilina, S. V. Dutova, N. G. Polshcha, N. V. Khanarin, T. S. Kulakova

“…The article points on the review of the main modern laboratory tests for atherosclerotic plaques assessment. The opportunities discussed for the study of cellular contents of the plaques, as functional evaluation of the cells in plaques.…”
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Association of a pace of aging epigenetic clock with rate of cognitive decline in the Framingham Heart Study Offspring Cohort by Micah J. Savin, Haoyang Wang, Heming Pei, Allison E. Aiello, Stephanie Assuras, Avshalom Caspi, Terrie E. Moffitt, Peter A. Muenning, Calen P. Ryan, Baoyi Shi, Yaakov Stern, Karen Sugden, Linda Valeri, Daniel W. Belsky

“…RESULTS Participants with faster DunedinPACE had poorer cognitive functioning at baseline and experienced more rapid cognitive decline over follow‐up. …”
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Macrophage activation syndrome in COVID-19 by K. N. Grigorieva, V. O. Bitsadze, J. Kh. Khizroeva, M. V. Tretyakova, D. V. Blinov, V. I. Tsibizova, D. A. Ponomarev, A. S. Shkoda, E. A. Orudzhova, E. Grandone, G. Rizzo, A. D. Makatsariya

“…The novel coronavirus epidemic is characterized by high rates of morbidity and relatively high mortality. Laboratory test results in patients include leukopenia, an increase in liver function tests and ferritin levels reaching hundreds, and sometimes thousands of units. …”
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The Impact of Edentulism and Periodontitis on Cognition by Lauren Berard, Miou Zhou

“…Both in vivo and in vitro studies have identified key pathogens, molecules, or cellular pathways that contribute to a more comprehensive understanding of the pathophysiologic processes that link different types of oral disease to cognitive brain function.Practical Implications The correlation between oral disease and cognitive impairment has been well established but further exploration of the molecular and cellular mechanisms underlying these relationships can provide therapeutic implications and stress the importance of oral health and preventative care.AbbreviationsAD: Alzheimer’s Disease; AFT: animal fluency test; BOP: bleeding on probing; BGI: biofilm-gingival interface; CAL: clinical attachment loss; CDT: clock drawing test; CERAD: Consortium to Establish a Registry for Alzheimer’s Disease word learning test; CNS: central nervous system; CP: chronic periodontitis; DSST: digital substitution test; IL-1β: interleukin 1β; IL-6: interleukin 6; LC: locus coeruleus; MMP: matrix metalloproteinase; MMSE: Mini-Mental Status Examination; MoCA: Montreal Cognitive Assessment; MRI: Magnetic Resonance Imaging; MWM: Morris water maze; NO: nitric oxide; PDL: periodontal ligament; PISA: periodontal inflamed surface area; PP2A: protein phosphatase 2A; RABL: radiographic alveolar bone loss; RANKL: Receptor activator of nuclear factor-κB ligand; SCT: spatial copying task; TLR4: toll-like receptor 4; TNF-α: tumor necrosis factor α; Vmes: Mesencephalic trigeminal nucleus.…”
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Association between distress tolerance and cannabis use disorder symptoms is stronger among U.S. young adults who identify as Hispanic and non-Hispanic Black by Jessica P. Orea, Haylee K. DeLuca Bishop, Kim Pulvers

“…One important yet understudied behavioral factor linked with CUD is Distress Tolerance (DT), and it is unknown whether this association varies as a function of race/ethnicity, despite health disparities. …”
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Thiostrepton-Nanomedicine, a TLR9 Inhibitor, Attenuates Sepsis-Induced Inflammation in Mice by K. Esparza, S. D. Oliveira, M. Castellon, R. D. Minshall, H. Onyuksel

“…Moreover, plasma levels of pro-inflammatory cytokines (interleukin 6 and tumor necrosis factor-alpha) and NO derivatives were also reduced, whereas renal and hepatic function biomarkers creatinine and aspartate transferase were significantly improved. …”
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Differential Evolution-Based Transient Search Optimizer for Image Multi-Thresholding Problem by Nitin Mittal, Supreet Singh, Lalit Kumar, Gurpreet Kaur, Vikas Mittal, A. Johnson Santhosh

“…This study aims to investigate the thresholding performance of well-recognized fitness function called Kapur’s entropy, for a selected threshold. …”
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A study of the efficacy and safety of plaque psoriasis treatment by TNF‐α and IL‐17A inhibitor biologics in patients who received the inactivated SARS‐CoV‐2 vaccine by Shuhong Ye, Hong Sun, Zining Xu, Bingyang Xu, Na Wu, Jiawen Wu

“…Results After inactivated COVID‐19 vaccination, biologics retained considerable advantages in terms of improving skin lesions (measured by PASI) and quality of life (measured by DLQI), compared with conventional treatment (p < 0.05 and p < 0.01, respectively). Routine blood tests and hepatorenal function analyses suggested that inactivated SARS‐CoV‐2 vaccines did not alter the safety of biologics treatment (p > 0.05). …”
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Edaravone Improves Streptozotocin-Induced Memory Impairment via Alleviation of Behavioral Dysfunction, Oxidative Stress, Inflammation, and Histopathological Parameters by Mahdieh Anoush, Soroush Bijani, Fatemeh Moslemifar, Fatemeh Jahanpour, Ali Kalantari-Hesari, Mir-Jamal Hosseini

“…Our results demonstrated that administration of STZ induced memory impairment in the Morris water maze (MWM) test and decreased the discriminative factor in novel object recognition (NOR). …”
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Analysis of Support Design in Weak Rock Drift Using a Systematic Approach by Xingdong Zhao, Shujing Zhang, Huaibin Li, Guoju Chen, Pengqiang Zhang

“…The factor of safety (FOS) of 8.28 of the combination support system is much more than the FOS of 1.5 for permanent drift. …”
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Neuroprotective Effects of ZiBuPiYin Recipe on db/db Mice via PI3K-Akt Signaling Pathway by Activating Grb2 by Wei-ming Ren, Ze-bin Weng, Xin Li, Li-bin Zhan

“…Oral glucose tolerance and insulin tolerance tests were used to assess insulin sensitivity. Morris water maze (MWM) tests were used to assess memory function. …”
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Biotin Mitigates Alcohol Withdrawal‐Induced Anxiety and Depression by Regulating Serotonin Metabolism, BDNF, Inflammation, and Oxidative Stress in Rats by Dawood Hossaini, Adam Khan Alipour, Meysam Sajjadi, Mustafa Ansari, Murtaza Haidary

“…Behavioral assessments included the Open Field Test, Elevated Plus Maze, and Forced Swimming Test, administered post‐withdrawal to evaluate anxiety and depression behaviors. …”
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Preparation of Aloe vera extract-loaded chitosan nanoparticles for the controlled delivery of extract phytochemicals in carbon tetrachloride-induced liver injury rat model by Omar Ashraf, Alyaa Farid, Gehan Safwat

“…Abstract Background A significant contributing factor to liver damage is drug consumption. Phytochemicals of Aloe vera extract are effective against a variety of diseases. …”
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Dysregulated mTOR networks in experimental sporadic Alzheimer’s disease by Suzanne M. de la Monte, Ming Tong

“…Its broad impact on brain structure and function suggests that mTOR is likely an important therapeutic target for AD.ObjectiveThis study characterizes temporal lobe (TL) mTOR signaling abnormalities in a rat model of sporadic AD neurodegeneration.MethodsLong Evans rats were given intracerebroventricular injections of streptozotocin (ic-STZ) or saline (control), and 4 weeks later, they were administered neurobehavioral tests followed by terminal harvesting of the TLs for histopathological study and measurement of AD biomarkers, neuroinflammatory/oxidative stress markers, and total and phosphorylated insulin/IGF-1-Akt-mTOR pathway signaling molecules.ResultsRats treated with ic-STZ exhibited significantly impaired performance on Rotarod (RR) and Morris Water Maze (MWM) tests, brain atrophy, TL and hippocampal neuronal and white matter degeneration, and elevated TL pTau, AβPP, Aβ, AChE, 4-HNE, and GAPDH and reduced ubiquitin, IL-2, IL-6, and IFN-γ immunoreactivities. …”
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Plasma sCD14 as a biomarker to predict pulmonary exacerbations in cystic fibrosis. by Bradley S Quon, David A Ngan, Pearce G Wilcox, S F Paul Man, Don D Sin

“…<h4>Background</h4>One in four cystic fibrosis (CF) patients diagnosed with a pulmonary exacerbation will not recover their baseline lung function despite standard treatment. This highlights the importance of preventing such events. …”
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Predicting the Electrical Conductivity of Partially Saturated Frozen Porous Media, a Fractal Model for Wide Ranges of Temperature and Salinity by Haoliang Luo, Damien Jougnot, Anne Jost, Jidong Teng, Aida Mendieta, Gang Lin, Luong Duy Thanh

“…The predicted values of the apparent formation factor also agree very well with the experimental data. …”
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Stellate ganglion block attenuates chronic stress induced depression in rats. by Weiwei Wang, Weidong Shi, Hua Qian, Xijin Deng, Tong Wang, Wenzhi Li

“…Stress-induced effects and the function of SGB were assessed using measures of body weight, coat state, sucrose consumption, and behavior in open-field and Y-maze tests. …”
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