Improvement of electrospark deposition technology of steel units for drilling rigs and mining equipment by D. N. Korotaev, E. V. Ivanova

“…In this regard, there is a need to create functional coatings with unique physical, mechanical and operational properties.Aim. …”
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Seizure-like behavior and hyperactivity in napb knockout zebrafish as a model for autism and epilepsy by Kyung Chul Shin, Waseem Hasan, Gowher Ali, Doua Abdelrahman, Tala Abuarja, Lawrence W. Stanton, Sahar I. Da’as, Yongsoo Park

“…Abstract We identified N-ethylmaleimide-sensitive factor attachment protein beta (NAPB) as a potential risk gene for autism and epilepsy. …”
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Effects of acanthoic acid on TNF-α gene expression and haptoglobin synthesis by H-S. Kang, H. K. Song, J-J. Lee, K-H. Pyun, I. Choi

“…Tumour necrosis factor-α (TNF-α) is a major proinflammatory cytokine inducing the synthesis and release of many inflammatory mediators. …”
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Exploring new Frontiers in dry eye Disease: Treatments, mechanisms, and diagnostic innovations a comprehensive review by K. Narendra, Sonali K. Singh, C.K. Deepa, S. Meghana, K.R. Akanth, M. Manjushree, D. Raajasubramaniyan, S. Srinivasan, R. Murali, H.N. Sowbhagya

“…Lifestyle modifications and nutritional supplements, such as omega-3 fatty acids and antioxidants, are also explored.Mechanistic insights cover tear film instability, inflammatory pathways, neuropathic pain, and meibomian gland dysfunction, emphasizing recent findings on the ocular surface microbiome, genetic and epigenetic factors, and chronic inflammation. Diagnostic innovations include AI and machine learning integration, advanced imaging techniques, tear film analysis, and functional tests, enhancing early detection and monitoring.Emerging research on gene therapy, stem cell therapy, ocular surface microbiota, and gene editing technologies like CRISPR is examined for future treatment potential. …”
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Using artificial intelligence and promoter-level transcriptome analysis to identify a biomarker as a possible prognostic predictor of cardiac complications in male patients with Fa... by Hiroshi Kobayashi, Norio Nakata, Sayoko Izuka, Kenichi Hongo, Masako Nishikawa

“…To predict cardiac complications of Fabry disease, we extracted RNA from the venous blood of patients for cap analysis of gene expression (CAGE), performed likelihood ratio tests for each RNA expression dataset obtained from individuals with and without cardiac complications, and analyzed the correlation between cardiac functional factors observed using magnetic resonance imaging data extracted using artificial intelligence algorithms and RNA expression. …”
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Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model by Yong Wha Moon, Nahee Park, Kamal Pandey, Sei Kyung Chang, Ah-Young Kwon, Young Bin Cho, Jin Hur, Nar Bahadur Katwal, Seung Ki Kim, Seung Ah Lee, Gun Woo Son, Jong Min Jo, Hee Jung Ahn

“…Early increase in serum tumor necrosis factor α levels, late increase in serum interleukin 6 levels and increase in tumor-infiltrating CD8+ T lymphocytes correlated more with a durable response over 60 days than with a non-durable response.Conclusions Our CD34+ humanized mouse model is the first in vivo platform for testing the long-term efficacy of anticancer immunotherapies and biomarkers, given that none of the preclinical models has ever been evaluated for such a long duration.…”
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Kidney Injury in Children Infected with HIV, Followed at the Teaching Hospital of Borgou (Benin): Epidemiological and Clinical Aspects by Séraphin Ahoui, Falilatou Agbeille, Gerard Kpanidja, Alphonse Noudamadjo, Muriel Fridzie Toutche, Bruno Leopold Agboton, Evariste Eteka, Jacques Vigan, Adedemy Julien Didier, Joseph Agossou

“…Comparisons were made using the Chi- square test or Fisher’s exact test. The identification of associated factors was possible using a multiple logistic regression model at 5% threshold. …”
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Effects of liver-specific LCMT1 gene knockout on glycolipid metabolism, learning and memory in mice by CHEN Sihong, TANG Tingting, CAI Haiqing, WANG Xinhang, WANG Minghong, PENG Yang, ZHANG Minhua, WEI Meifang, ZHU Congrui, ZHANG Jing, LI Xiaoying, LU Cailing, TANG Shen, LI Xiyi

“…HE staining of the liver tissue and serum liver function tests showed that, compared with WT mice, the liver-specific LCMT1 knockout had no effect on liver tissue morphology, serum AST and ALT levels (P > 0.05), and did not impair liver function. …”
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Low Carbon Economic Dispatch of Gas Electricity Coupling System Considering Carbon Capture and Hydrogen Mixing in Gas Grid by Yuxuan YANG, Dongliang GAO, Yiming CHEN, Buxiang ZHOU, Yang CHEN, Tianlei ZANG

“…Then the sum of incentive carbon trading cost and operation cost is used as the objective function. Finally, an arithmetic test is carried out based on the improved Belgian 20-node natural gas system and IEEE 39-node power system models. …”
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What are the Necessary Psychological Well-being Conditions for Women Entrepreneurs to Feel Effective? by Sayonara de Fátima Teston, Patrick Zawadzki, Hilka Pelizza Vier Machado, Carla Fabiana Cazella

“…We validated the instruments with robust confirmatory factor analysis and tested the statements through multiple necessary condition analysis (NCA). …”
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Critical Design and Characterization Methodology for a Homemade Three-Axis Fluxgate Magnetometer Measuring Ultra-Low Magnetic Fields by Hava Can, Fatma Nur Çelik Kutlu, Peter Svec, Ivan Skorvanek, Hüseyin Sözeri, Çetin Doğan, Uğur Topal

“…Additionally, the paper introduces a model function in matrix form to relate the magnetometer’s output voltage to the measured magnetic field, incorporating temperature dependency and cross-field effects. …”
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Bruxism and other jaw loading behaviours are associated with somatic symptoms and psychological distress in orofacial pain-free adults: a cross-sectional study by Nontawat Chuinsiri, Nontawat Chuinsiri, Peungchaleoy Thammanichanon, Peungchaleoy Thammanichanon, Pornputthi Puttaravuttiporn, Wittawat Mongkolchart, Chadatorn Chudet, Chadatorn Chudet, Sirada Thongraksri, Sirada Thongraksri

“…Among orofacial pain patients, non-functional oral behaviours have been observed in association with elevated psychosocial factors. …”
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Harnessing Polyethylene Glycol 3350 for Enhanced Peripheral Nerve Repair: A Path to Accelerated Recovery by Erdinç Tunç, Ejder Saylav Bora, Oytun Erbaş

“…Electromyography (EMG) and the inclined plane test assessed functional recovery. Sciatic nerve tissues were analyzed histologically and biochemically, including nerve growth factor (NGF), heat shock protein 70 (HSP-70), and malondialdehyde (MDA) levels. …”
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−254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children by Xinyu Kuang, Qian Zhou, Zhuying Li, Yujie Hu, Yulin Kang, Wenyan Huang

“…In conclusion, the −254C>G SNP is a gain-of-function variation of the TRPC6 gene, and it is also an early and effective factor for predicting steroid-resistant nephrotic syndrome (SRNS) in Chinese children.…”
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Association of Forced Vital Capacity with the Developmental Gene NCOR2. by Cosetta Minelli, Charlotte H Dean, Matthew Hind, Alexessander Couto Alves, André F S Amaral, Valerie Siroux, Ville Huikari, María Soler Artigas, David M Evans, Daan W Loth, Yohan Bossé, Dirkje S Postma, Don Sin, John Thompson, Florence Demenais, John Henderson, SpiroMeta consortium, CHARGE consortium, Emmanuelle Bouzigon, Deborah Jarvis, Marjo-Riitta Järvelin, Peter Burney

“…For SNPs with evidence of replication, effects on the expression levels of nearby genes in lung tissue were tested in 1,111 lung samples (Lung eQTL consortium), with further functional investigation performed using public epigenomic profiling data (ENCODE).…”
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SUBCLINICAL CARDIOVASCULAR SYSTEM INVOLVEMENT IN RHEUMATIC DISEASES by A. L. Maslyansky, N. E. Zvartau, E. P. Kolesova, A. V. Kozlyonok, E. Yu. Vasilyeva, V. I. Mazurov, A. O. Konradi, E. V. Shlyakhto

“…Estimated glomerular filtration rate was calculated by MDRD equation. Functional assessment included EchOCG, ultrasound visualization of carotid arteries and vessel stiffness evaluation. …”
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Coordinated changes in midkine expression and midkine-associated multiomic profile in glioma microenvironment by Mieszko Lachota, Katarzyna Zielniok, Agata Góźdź, Patrycja Szpak, Ilona Kalaszczyńska, Radosław Zagożdżon

“…To investigate MDK’s function in glioma, we integrated four RNA-Seq datasets into a harmonized cohort of 1,017 adult gliomas, including 256 GBM samples. …”
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Brachial plexus block in American Kestrels (Falco sparverius) using a peripheral nerve stimulator with different doses of lidocaine by Ana Paula Morel, Maria Lucia Rösler, Ana Júlia Fazenda de Souza, Márcio Nunes Corrêa, Raqueli Teresinha França

“…These findings suggest that achieving motor blockade with lidocaine in small birds of prey like F. sparverius may be challenging using the tested doses and volumes and that the anesthetic volume is likely a determining factor for successful blockade. …”
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Overall Ultra-high Energy Neutrino Emission from GRBs During Jet Expansion by Qinyuan Zhang, Zhuo Li

“…The faster magnetic field decay leads to larger UHE neutrino fluence, and the UHE neutrino spectra are weakly dependent on the energy dissipation radius and the jet Lorentz factor. Observations of prompt EeV neutrinos from GRBs by the next-generation neutrino telescopes, e.g., GRAND and IceCube-Gen2, will test the hypothesis of GRBs as UHECR sources and probe the physics of GRB jets.…”
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Research on Acoustic Field Correction Vector-Coherent Total Focusing Imaging Method Based on Coarse-Grained Elastic Anisotropic Material Properties by Tianwei Zhao, Ziyu Liu, Donghui Zhang, Junlong Wang, Guowen Peng

“…An ultrasound simulation model was developed based on material backscatter diffraction results, and the scattering attenuation compensation factor was optimized. The acoustic field correction function was derived by combining acoustic field directivity with diffusion attenuation compensation. …”
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