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4001
Opportunities for immunocorrection aiming for reduction of morbidity in the areas with adverse occupational and environmental conditions
Published 2021-01-01“…Following the immunotropic therapies, the subjects showed an increase in relative content of CD3+, CD4+, and CD8+ subpopulations, normalization of functional oxygen-dependent metabolism of polymorphonuclear neutrophil granulocyte system in the NBT test, as well as harmonization of the content of serum immunoglobulin contents. …”
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4002
Evaluation of Hippocampal Microanatomy and Neuro-Biomarkers Following Administration of Silver Nanoparticles Conjugated with Tenofovir Disoproxil Fumarate in Experimental Diabetic...
Published 2024-12-01“…This study shows that AgNPs-TDF restores various alterations in the hippocampus and improves cognitive functions in diabetic rats.…”
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4003
T-cell agonists in cancer immunotherapy
Published 2020-10-01“…Other mechanisms for promoting antitumor T-cell function are the targeting of costimulatory molecules expressed on the surface of T cells, such as 4-1BB, OX40, inducible T-cell costimulator and glucocorticoid-induced tumor necrosis factor receptor. …”
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4004
Wafer-Scale Experimental Determination of Coupling and Loss for Photonic Integrated Circuit Design Optimisation
Published 2025-03-01“…Third, we demonstrate how curve fitting of loss and coupling coefficients as a function of the gaps can be used to estimate the optimal gap that realizes critical coupling with a significantly reduced number of manufactured test structures needed to find optimal design parameters.…”
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4005
Does Urban Polycentric Structure Improve Carbon Emission Efficiency? A Spatial Panel Data Analysis of 279 Cities in China from 2012 to 2020
Published 2024-12-01“…Urban spatial structure, shaped by human intervention in the natural environment, impacts the functional space and socioeconomic efficiency of cities. …”
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4006
Exploring the associations of plasma proteins with frailty based on Mendelian randomization
Published 2024-12-01“…Methods Associations of plasma proteins with frailty were assessed using inverse variance weighted (IVW), MR-Egger regression, weighted median, maximum-likelihood method, and MR-PRESSO test. Protein-protein interaction network construction and gene ontology functional enrichment analysis were conducted based on MR-identified target proteins. …”
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4007
Impaction of Deciduous and Permanent Teeth Related to Local Obstacles: A Retrospective Study of 10 Years of Institutional Experience
Published 2025-07-01“…<b>Background</b>: Dental eruption pathways could be influenced by several factors, both general and local, with different prevalence and morbidity. …”
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4008
Spectrophotometric Analysis of Dental Staining Induced by Different Pulpotomy Materials
Published 2025-01-01“…Statistical Analysis: The statistical tests used were the two-factor ANOVA test and the Tukey test, which allowed the multiple comparisons of the ΔE parameter between the different groups and within the same group as a function of time. …”
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4009
Role of Leukocytospermia in the Management of Male Infertility: Decoding a Mystery for the Busy Clinicians
Published 2025-07-01“…Leukocytospermia, defined as a leukocyte concentration in semen exceeding 1×106 leukocytes/mL, significantly impacts male reproductive health by affecting sperm functionality and fertility outcomes. This condition arises from various etiological factors, including infections, autoimmune responses, lifestyle factors, and other physiological conditions. …”
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4010
The development of the Polish version of the Compassionate Engagement and Action Scales.
Published 2025-01-01“…In the first, the model includes a general compassion for others factor alongside specific factors for engagement and actions. …”
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4011
Direct and indirect effects of spliceosome disruption compromise gene regulation by nonsense-mediated mRNA decay
Published 2025-08-01“…Pre-mRNA splicing, carried out in the nucleus by a large ribonucleoprotein machine known as the spliceosome, is functionally and physically coupled to the mRNA surveillance pathway in the cytoplasm called nonsense-mediated mRNA decay (NMD). …”
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4012
The impact of environmental quality components on enhancing social health: a case study on residential complexes of Ardabil city
Published 2025-06-01“…For data analysis, SPSS and LISREL software were employed, along with regression analysis, Pearson tests, and structural equation modeling. Results: The findings revealed that environmental quality components—such as economic factors, socio-human aspects, environmental dimensions, functional and physical characteristics of residential units, aesthetics, visual appeal, use of natural elements, lighting, safety, and perceptual meanings—significantly impact social health enhancement. …”
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4013
Role of Toll-like receptor gene polymorphism in pathogenesis of new coronavirus infection
Published 2023-11-01“…These reactions lead to the production of the most important antiviral response substances. The factors that lead to reduced / increased expression of TLR genes include gene polymorphisms which control the functioning of the immune system in some ways, thus causing a reduced, or hyperinflammatory response to an infectious agent. …”
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4014
Zebra optimization algorithm incorporating opposition-based learning and dynamic elite-pooling strategies and its applications.
Published 2025-01-01“…During experimental evaluation, the efficiency of OP-ZOA was verified using the CEC2017 test functions, demonstrating superior performance compared to seven recently proposed meta-heuristic algorithms (Bloodsucking Leech Algorithm (BSLO), Parrot Optimization Algorithm (PO), Polar Lights Algorithm (PLO), Red-tailed Hawk Optimization Algorithm (RTH), Bitterling Fish Optimization Algorithm (BFO), Spider Wasp Optimization Algorithm (SWO) and Zebra Optimization Algorithm (ZOA)). …”
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4015
Vision guides the twilight search for oviposition sites of the Asian tiger mosquito, Aedes albopictus.
Published 2024-11-01“…Vision plays an important role in this behavior, and factors such as the shape, size, and color of the container, light intensity, polarization, spectrum, and other visual cues guide the search for suitable oviposition sites, but the mechanistic factors driving this behavior are unclear.…”
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4016
Peculiarities of the morphology of the fish stomach
Published 2025-03-01“…Histochemical characteristics of the stomach of fish can serve as a theoretical basis for the development of a normal stomach test system for detecting functional changes under the influence of environmental factors.…”
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4017
Determinants of child physical health development in Bangladesh: a study of key socioeconomic and cultural influences
Published 2025-07-01“…To examine the associations between variables, the Mann-Whitney U and Kruskal-Wallis H tests were conducted for bivariate analysis, while a generalized log-normal regression model was employed to assess the impact of various socioeconomic and demographic factors on children’s physical health development. …”
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4018
The effect of transcranial alternating current stimulation over the supplementary motor area on bimanual coordination in elderly people
Published 2023-01-01“…The Bonferroni tests revealed the significant improvement of bimanual coordination in the tACS condition compared to the sham condition in all retention and transfer tests (P<0.05).Conclusion: The findings highlights the potential use of offline beta tACS over the SMA as a modulatory factor for enhancing bimanual coordination in the elderly women.…”
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4019
Improved Manta Ray Foraging Optimization for PID Control Parameter Tuning in Artillery Stabilization Systems
Published 2025-04-01“…Comparative experiments using five benchmark test functions demonstrate that the IMRFO algorithm outperforms five commonly used heuristic algorithms in four cases. …”
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4020
Clinical spectrum and long-term outcomes of antibody-negative severe autoimmune encephalitis: a retrospective study
Published 2025-05-01“…Additionally, 30.6% of patients had relapsed, with refractory status epilepticus being an independent risk factor for relapse.ConclusionAlthough patients with antibody-negative severe AE experience significant disability in the early stages of their disease, the majority eventually regain independent functioning. …”
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