Optimization of medium components for the production of exopolysaccharide by Lycoperdon pyriforme Schaeff.: Pers. using response surface methodology by MA Xiaokui, JIANG Hua, LI Junzhi, CHEN Yong, HE Xiaojing

“….: Pers. is one of medicinal macro-fungi, which has become an attractive topic as a functional food and as a source for the development of drugs and nutraceuticals. …”
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Towards propagation of epidermal cells for wound repair: glass, as cell culture substrate, enhances proliferation and migration of human keratinocytes by Hady Shahin, Hady Shahin, Hady Shahin, Ingrid Steinvall, Ingrid Steinvall, Folke Sjöberg, Folke Sjöberg, Moustafa Elmasry, Moustafa Elmasry, Ahmed El-Serafi, Ahmed El-Serafi

“…Proliferation, migration, DNA methylation, as well as gene and protein expression were assessed to characterize the effect of the tested culture substrates on keratinocytes at the molecular and functional levels.ResultsKeratinocytes cultured on glass exhibited faster proliferation, global DNA demethylation and upregulation of epidermal differentiation markers. …”
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Extracorporeal Membrane Oxygenation as Life Support in Neonatal Respiratory Failure: A Single-Center Cohort Study and a Systematic Review by Raffaele Falsaperla, Rosanna Zanai, Ausilia Desiree Collotta, Vincenzo Sortino, Giovanna Vitaliti, Carla Cimino, Bruna Scalia, Marco Simone Vaccalluzzo, Michela Spatuzza, Grete Francesca Privitera, Alfredo Pulvirenti, Piero Pavone, Martino Ruggieri, Andrea Marino, Salvatore Agati

“…Conclusions: ECMO functions as life support, although mortality and morbidity risks are high.…”
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International Mind, Activities and Urban Places (iMAP) study: methods of a cohort study on environmental and lifestyle influences on brain and cognitive health by Amanda J Wheeler, Kaarin J Anstey, Mark J Nieuwenhuijsen, Ester Cerin, Nicola T Lautenschlager, David W Dunstan, Bin Jalaludin, Basile Chaix, James F Sallis, Michael Y Ni, Takemi Sugiyama, Anthony Barnett, Karen Caeyenberghs, Govinda Poudel, David Donaire-Gonzalez, Rachel Tham, Luke Knibbs, Linwei Tian, Yih-kai Chan, Alison Carver

“…Two assessments taken 24 months apart will capture changes in brain and cognitive health. Cognitive function is gauged with a battery of eight standardised tests. …”
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A retrospective cohort study of the efficacy and safety of oral azvudine versus nirmatrelvir/ritonavir in elderly hospitalized COVID-19 patients aged over 60 years by Bo Yu, Haiyu Wang, Guangming Li, Junyi Sun, Hong Luo, Mengzhao Yang, Yanyang Zhang, Ruihan Liu, Ming Cheng, Shixi Zhang, Guotao Li, Ling Wang, Guowu Qian, Donghua Zhang, Silin Li, Quancheng Kan, Jiandong Jiang, Zhigang Ren

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Relationship Between Muscle Tone and Elasticity: Simultaneous Quantitative Assessment Using Train-of-Four Monitoring and Continuous Shear Wave Elastography During Anesthesia Induct... by Hitoshi Shitara, Tadanao Hiroki, Ren Koda, Tsuyoshi Sasaki, Masataka Kamiyama, Ryosuke Miyamoto, Kurumi Nakase, Fukuhisa Ino, Takuma Kachi, Rie Mieda, Chizu Aso, Yoshiki Yamakoshi, Shigeru Saito, Hirotaka Chikuda

“…These findings have implications for improving intraoperative muscle function assessments and advancing the application of C-SWE in clinical practice.…”
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An Experimental Study of the Feasibility of Identifying the Impact Damages of Reinforced Concrete Piers Using a Modal Frequency Method by Xiwu Zhou, Wenchao Zhang, Yushen Gao, Guoxue Zhang, Mengdan Wen

“…Also, the modal frequency damage factors were determined to be functions of the ultrasonic wave velocity damage factors. …”
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The GLP-1 receptor agonist liraglutide inhibits necroptosis and neuroinflammation in a mouse model of Parkinson’s disease with diabetes co-morbidity by Xiaomin Zhang, Pengyang Du, Bo Bai, Peng Feng, Xia Lian, Christian Hölscher, Yongqing Wang, Guofang Xue

“…After that, body weight and blood glucose of each group mice were measured, and the open field experiment and gait analysis experiment were performed to detect the motor and non-motor symptoms of mice, western blotting and immunohistochemistry experiments were performed to test the levels of necroptosis-related proteins tumor necrosis factor-α (TNF-α), receptor interacting serine/threonine kinase 1 (RIP1) and neuroinflammation-related proteins nuclear factor kappa-B p-p65 (NF-κB p-p65), nuclear factor kappa-B p65 (NF-κB p65), interleukin-1 beta (IL-1β), and monocyte chemoattractant protein-1 (MCP-1).ResultsThe GLP-1 receptor agonist liraglutide inhibited necroptosis and neuroinflammation via TNF-α signaling in diabetic PD mice, decreasing blood glucose and improving motor function and mood. …”
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Single-nucleotide polymorphisms in dizygotic twin ovine fetuses are associated with discordant responses to antenatal steroid therapy by Erin L. Fee, Haruo Usuda, Sean W. D. Carter, Hideyuki Ikeda, Tsukasa Takahashi, Yuki Takahashi, Yusaku Kumagai, Michael W. Clarke, Demelza J. Ireland, John P. Newnham, Masatoshi Saito, Sebastian E. Illanes, Binny Priya Sesurajan, Liang Shen, Mahesh A. Choolani, Gokce Oguz, Adaikalavan Ramasamy, Sara Ritchie, Andrew Ritchie, Alan H. Jobe, Matthew W. Kemp

“…We aimed to test the degree of concordance in preterm lung function, and correlate this with genomic, transcriptomic, and pharmacokinetic variables in preterm dizygotic twin ovine fetuses. …”
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MULTI-OBJECTIVE ROBUST OPTIMIZATION DESIGN OF COMPLIANT HINGE BASED ON BP NEURAL NETWORK (MT) by WU JianJun, LI JiaHui

“…The experimental results show that the comprehensive evaluation function of the compliant hinge is better, which achieves the purpose of robust optimization design, and proves the effectiveness of the method.…”
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The RITE Assay: Identifying Effectors that Target the Transcription Machinery Using Phage Display Technology by Joan M. Mazzarelli, Robert P. Ricciardi

“…Candidate effectors from the homology search are synthesized from recombinant clones and tested for their abilities to bind to the target protein and to functionally modulate transcription in vivo when co-expressed with the transcriptional target protein. …”
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Business and entrepreneurship is declining as scholarly field: Empirical evidence. by Wim Naudé

“…Estimates from an ideas production function suggest that the field is getting fished out and that researchers may be stepping on one another's toes. …”
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Fufang Zhenzhu Tiaozhi capsule attenuates renal damage by restoring Th17/Treg balance in diabetic db/db mice by Yiqi YANG, Haibo TAN, Xiaoyu ZHANG, Minyi HUANG, Weijian BEI, Jiao GUO

“…The inflammation factors including TNF-α, TGF-β, IL-6, IL-8, and IL-10 were detected by ELISA kits. …”
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Electroacupuncture Improves Learning and Memory Impairment in Rats with Cerebral Ischemia/Reperfusion Injury by Promoting Microglia/Macrophage M2 Polarization Through Nrf2/HO-1 Pat... by Xiao Y, Bai Y, Sun K, Wan J, Chen L, Chen S, Wang Y, Li W, Liu A

“…The goal of this study was to investigate whether EA improves learning and memory deficits in MCAO rats by regulating microglia/macrophage polarization through the nuclear factor red lineage 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway.Methods: Sprague-Dawley rats were subjected to MCAO modeling and treated with EA 24 hours post-MCAO for a period of two weeks. …”
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Effects and underlying mechanisms of novel phenothiazine derivative DA414 in rats with intracerebral hemorrhage by MA Yufan, WANG Bingqiao, LIN Sen

“…The integrity of the blood-brain barrier (BBB) was assessed by Evans blue staining, and the biosafety of DA414 for the liver, kidneys and heart was assessed by HE staining and clinical biochemical tests. Results‍　‍DA414 significantly promoted the absorption of hematoma, reduced neuronal injury, and improved neurological function scores. …”
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A formal notation of legal rules applicable in the local space by Anna M. Barańska, Konrad Eckes

“…The established hierarchy is the first factor considered. The second factor is variability over time. …”
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Selective recruitment of beneficial microbes in the rhizosphere of maize affected by microbial inoculants, farming practice, and seasonal variations by Ioannis D. Kampouris, Theresa Kuhl-Nagel, Jan Helge Behr, Loreen Sommermann, Doreen Babin, Davide Francioli, Rita Zrenner, Susanne Kublik, Michael Schloter, Uwe Ludewig, Kornelia Smalla, Günter Neumann, Rita Grosch, Joerg Geistlinger

“…Abstract Background Plant beneficial microorganisms as inoculants can improve crop performance, but factors affecting their impact on plant performance under field conditions remain unclear, thereby limiting their use in farming. …”
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Effect of high-intensity anaerobic exercise on electrocortical activity in athletes and non-athletes. by Élida Costa, Mariana Gongora, Juliana Bittencourt, Victor Marinho, Mauricio Cagy, Silmar Teixeira, Eduardo Nicoliche, Isabelle Fernandes, Danilo Fagundes, Caroline Machado, Juliana Dias, Renan Vicente, Pedro Ribeiro, Daya S Gupta, Bruna Velasques, Henning Budde

“…<h4>Aim</h4>The present study aims to verify the information processing in athletes through electroencephalography, analyze cortical areas responsible for cognitive functions related to attentional processing of visual stimuli, and investigate motor activity's influence on cognitive aspects. …”
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PO90 | Acquired hemophilia A with high-titer inhibitor in a patient with cardiovascular and metabolic comorbidities

“…At discharge, the patient showed hemodynamic stability, no further arrhythmic episodes, resolution of hematomas, and partial functional recovery. Conclusions: AHA may present acutely and severely, even in patients without overt autoimmune disease. …”
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Method for Distinguishing the Digital Images in Different Formats by Kobozeva A.A., Bobok I.I., Kushnirenko N.I.

“…Nowadays, the energy systems are considered to be the main vital factor for the functioning of society. Today, this part of the infrastructure cannot exist without the informative infrastructure, so it needs efficient information and cyber protection. …”
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