Prediction of knee joint pain in Tai Chi practitioners: a cross-sectional machine learning approach by Yang Chen, Xiaojie Su, Fei Yao, Yushan Liu, Hua Xing, Yubin Ju, Zhiran Kang, Wuquan Sun, Lijun Yao, Li Gong

“…Dataset 1 was established by whether the participant had knee pain, and dataset 2 by whether the participant’s knee pain affected daily living function. Then both datasets were randomly assigned to a training and validating dataset and a test dataset in a ratio of 7:3. …”
Get full text

Antibody signatures elicited by potent and subpotent whole-cell pertussis vaccines in mice by Yetunde Adewunmi, Jennifer Doering, Prashant Kumar, Jozelyn V. Pablo, Andy A. Teng, Vu Huynh, Kathryn Secrist, David B. Volkin, Sangeeta B. Joshi, Joseph J. Campo, Nicholas J. Mantis

“…We then screened immune sera on a limited B. pertussis Tahoma I proteome array and identified >30 antigens whose antibody reactivity profiles either increased, decreased, or were unchanged as a function of wP potency. Moreover, virtually all the “indicator” antigens identified are known virulence factors or reactive with human convalescent sera, thereby establishing a potential link between wP potency and pertussis infection and immunity. …”
Get full text

Physical activity level and health-related quality of life in adults with multiple osteochondromas: a Dutch cross-sectional study by Ihsane Amajjar, Kuni Vergauwen, Nienke W. Willigenburg, Ivan P. J. Huijnen, Rob J. E. M. Smeets, S. John Ham

“…The PAL, physical and mental HRQOL were compared with reference scores of healthy subjects using a one-sample t-test. An a-priori defined theoretical framework (ICF-model) was used to select explanatory variables, including several psychological factors, for the multiple linear regression models of the dependent variables PAL and HRQOL. 342 patients (42.6% males) with a mean age of 41.8 ± 16.3 completed the survey. …”
Get full text

The diversity of local political agendas during COVID-19: A comparison of Mexican states by Enrique García-Tejeda, Juan Guillermo Vieira-Silva

“…At least for the case of COVID-19 in the short run, the size and diversity of local agendas in Mexico seem to be based on institutional factors, such as information processing according to bounded rationality, incremental solutions, and the functional labeling of local governments. …”
Get full text

Diagnostic potential of soluble TNF alpha receptor 1 in diabetic and hypertensive patients with renal impairment and UTI. by Fatin Ayoob Hameed, Ali Mansoor Al Ameri, Israa Hashim Saadoon

“…Several novel diagnostic markers are being under investigation nowadays. Tumor necrosis factor-alpha and its receptors are examples. Aim: The present study was conducted to evaluate the role of tumor necrosis factor α  receptor 1 (TNFR1) as a biomarker for detection of renal dysfunction. …”
Get full text

Model Predictive Current Control with Asymmetric Stacked Multilevel Inverter and LCL-Filter Based STATCOM by Mostafa Q. Kasim, Raaed Faleh Hassan

“…Therefore, this control strategy allows injecting harmonic current and reactive power compensation to reduce source current distortion and improve the voltage profile and power factor. The optimization mechanism reduces the cost function, which is a function of measuring the network current's deviation from the reference value and how the capacitor voltage deviates from the required values. …”
Get full text

Vasoreparative dysfunction of CD34+ cells in diabetic individuals involves hypoxic desensitization and impaired autocrine/paracrine mechanisms. by Yagna P R Jarajapu, Sugata Hazra, Mark Segal, Sergio Li Calzi, Chandra Jadhao, Kevin Qian, Sayak K Mitter, Mohan K Raizada, Michael E Boulton, Maria B Grant

“…We hypothesized that endothelial progenitor cells derived from individuals with diabetes would exhibit functional defects including inability to respond to hypoxia and altered paracrine/autocrine function that would impair the angiogenic potential of these cells. …”
Get full text

Model of quality of life in a group of people with chronic low back pain by Urszula Ziętalewicz, Kamilla Bargiel-Matusiewicz

“…We conducted a cross-sectional study in which a multi-module self-administered questionnaire examining biological factors, personality traits, personal values, body assessment, symptoms of depression and anxiety, functional status, general perception of health, life satisfaction, received social support, economic support, satisfaction of health care and sociodemographic factors was adopted. …”
Get full text

Psychological distress among workers at a mine by Yolanda Havenga, Michelle Bester

“…Conclusion: Psychological distress potentially impacts daily functioning for a third of employees, indicating a need for prevention and management interventions addressing personal, workplace and environmental factors. …”
Get full text

Research on bearing fault diagnosis based on improved northern goshawk algorithm optimizing SVM by WU Xiaojun, LI Quwei

“…In order to evaluate the performance of the improved algorithm, firstly, benchmark testing functions were used for experiments, and the improved algorithm was compared with existing optimization algorithms such as NGO, particle swarm optimization (PSO), sparrow search algorithm (SSA), etc. …”
Get full text

Modelling analysis of dietary behaviors and oral health status to assess the impact on the mental well-being of elderly individuals: a cross-sectional survey study by Chan Huang, Mingzhu Song, Xiao Wei, Xingyan Wang, Honglin Dai, Zhiqiong Gou, Feiyang Chenwu, Yanqiu Jiang, Jie Wan, Yurun Guo, Xiaoping Yu

“…The mental health of the elderly is influenced by a plethora of factors such as physical health, social support, lifestyle, and psychological aspects. …”
Get full text

Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk by Marios K. Georgakis, Rainer Malik, Omar El Bounkari, Natalie R. Hasbani, Jiang Li, Jennifer E. Huffman, Gabrielle Shakt, Reinier W. P. Tack, Tamara N. Kimball, Yaw Asare, Alanna C. Morrison, Noah L. Tsao, Renae Judy, Braxton D. Mitchell, Huichun Xu, May E. Montasser, Ron Do, Eimear E. Kenny, Ruth J. F. Loos, James G. Terry, John Jeffrey Carr, Joshua C. Bis, Bruce M. Psaty, W. T. Longstreth, Kendra A. Young, Sharon M. Lutz, Michael H. Cho, Jai Broome, Alyna T. Khan, Fei Fei Wang, Nancy Heard-Costa, Sudha Seshadri, Ramachandran S. Vasan, Nicholette D. Palmer, Barry I. Freedman, Donald W. Bowden, Lisa R. Yanek, Brian G. Kral, Lewis C. Becker, Patricia A. Peyser, Lawrence F. Bielak, Farah Ammous, April P. Carson, Michael E. Hall, Laura M. Raffield, Stephen S. Rich, Wendy S. Post, Russel P. Tracy, Kent D. Taylor, Xiuqing Guo, Michael C. Mahaney, Joanne E. Curran, John Blangero, Shoa L. Clarke, Jeffrey W. Haessler, Yao Hu, Themistocles L. Assimes, Charles Kooperberg, Jürgen Bernhagen, Christopher D. Anderson, Scott M. Damrauer, Ramin Zand, Jerome I. Rotter, Paul S. de Vries, Martin Dichgans

“…Methods Computationally predicted damaging or loss-of-function (REVEL > 0.5) variants within CCR2 were detected in whole-exome-sequencing data from 454,775 UK Biobank participants and tested for association with cardiovascular endpoints in gene-burden tests. …”
Get full text

Enhanced Chaotic Pseudorandom Number Generation Using Multiple Bernoulli Maps with Field Programmable Gate Array Optimizations by Leonardo Palacios-Luengas, Reyna Carolina Medina-Ramírez, Ricardo Marcelín-Jiménez, Enrique Rodriguez-Colina, Francisco R. Castillo-Soria, Rubén Vázquez-Medina

“…Moreover, by incorporating a scaling factor and a sine function, we develop a robust chaotic map, called the Sine-Multiple Modified Bernoulli Chaotic Map (SM-MBCM), which ensures a high degree of randomness, validated through statistical mechanics analysis tools. …”
Get full text

Early Active Exercise Improves MDA, SOD, and GSH Levels without Memory or NO Changes in Wistar Rats by Muhammad Hafiz Zuhdi Fairof, Arimi Fitri Mat Ludin, Nur Diyana Anas, Ainaa Husna, Ahmad Muhaimin Che Hasan, Amirul Hafiz Ahmad Abdullah, Farah Wahida Ibrahim, Adriyan Pramono, Nor Fadilah Rajab

“…However, the effects of exercise timing on cognitive function and oxidative stress remain unclear. One key factor in oxidative stress is nitric oxide (NO), an enzyme complex that produces reactive oxygen species (ROS) as part of normal cellular signaling. …”
Get full text

Impacts of Low-Order Stream Connectivity Restoration Projects on Aquatic Habitat and Fish Diversity by Xinfeng Li, Xuan Che, Xiaolong Chen, Changfeng Tian, Jiahua Zhang

“…Results indicate that (1) the post-restoration aquatic habitat significantly improved with marked increases in fish diversity metrics, where hydrochemical factors and species diversity exhibited the highest sensitivity to connectivity changes; (2) following restoration, the initially barrier-fragmented river segments (upstream, middle, downstream) exhibited significantly decreased differences in aquatic habitat and fish diversity, demonstrating progressive homogenization across reaches; (3) hydrological factors exerted stronger positive effects on fish diversity than hydrochemical factors did, particularly enhancing species diversity, with a significant positive synergistic effect observed between species diversity and functional diversity. …”
Get full text

Study on Identification of Construction Method for Ultra-Large-Span Tunnel by Xu Chongbang, Qin Youlin

“…Meanwhile, the macro form and quantitative method of test combinations under different levels of various factors were proposed to obtain the influence of each factor on the stability of tunnel surrounding rock, and thus the functional relations between various factors and tunnel stability were obtained. …”
Get full text

Computer‐Aided High Tibial Osteotomy—A Comparative Study of Commonly Used 3D Printing Technology and Navigation Application by Elvis Chun‐Sing Chui, Kyle Ka‐Kwan Mak, Randy Hin‐Ting Ng, Ericsson Chun‐Hai Fung, Mei‐Shuen Chan, Kai Yue, Lawrence Chun‐Man Lau, Clifford Long‐Fung Chan, Edmond Wing‐Fung Yau, Wei Zhao, Xiuyun Su, Jin Zhang, Jianglong Xu, Hongxun Sang, Guoxian Pei, Louis Wing‐Hoi Cheung, Sheung‐Wai Law, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung

“…Proper execution of HTO can preserve joint function and delay or avoid the need for total knee replacement. …”
Get full text

Protocol for a prospective cohort study to determine the multimodal biomarkers of delirium and new dementia after acute illness in older adults: ORCHARD-PS by Jessica Knight, Davide Simonato, Sarah Evans, Nicola G Lovett, Jasmine Ming Gan, Aubretia McColl, Lily Elderton, Meenu Vijayakumar Sheela, John Louca, Kinza Shahab, Mary Sneade, Nycola Muchenje, Mariya Fenchyn, Sarah Tamsin Pendlebury

“…Participants are interviewed as soon as possible after admission/assessment using a structured proforma.Data are collected on demographics, diagnosis and comorbidities, social and functional background. Delirium is assessed using the 4A’s test, Confusion Assessment Method (long-form), Observational Scale of Level of Arousal, Richmond Agitation-Sedation Scale and Memorial Delirium Assessment Scale and diagnosed using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria. …”
Get full text

Impact of Hypothermic Perfusion on Immune Responses and Sterile Inflammation in a Preclinical Model of Pancreatic Transplantation by Benoit Mesnard, MD, Sarah Bruneau, PhD, Stéphanie Le Bas-Bernardet, PhD, Etohan Ogbemudia, MD, Delphine Kervella, MD, PhD, Christophe Masset, MD, Mélanie Neel, PhD, M. David Minault, M. Jeremy Hervouet, Diego Cantarovich, MD, PhD, Jérôme Rigaud, MD, PhD, Lionel Badet, MD, PhD, Peter Friend, MD, PhD, Rutger Ploeg, MD, PhD, Gilles Blancho, MD, PhD, James Hunter, MD, PhD, Thomas Prudhomme, MD, Julien Branchereau, MD, PhD

“…We demonstrated that compared with static cold storage, hypothermic oxygenated perfusion is an effective modality for modulating endothelial function by increasing thrombomodulin expression and decreasing ischemia and vascular endothelial growth factor expression.…”
Get full text

Hydrogen Loss on Venus Driven by Photochemistry by Hao Gu, Jun Cui, Xiaoshu Wu, Xu Huang, Shiqi Wu, Wenlong Li, Jinjin Zhao, Haoyu Lu, Lei Li

“…Our findings provide valuable insights into the foundational understanding of photochemically driven H escape because the same mechanism should function in a much broader context.…”
Get full text