Comparative Analysis of Primary Sarcopenia and End‐Stage Renal Disease–Related Muscle Wasting Using Multi‐Omics Approaches by Daiki Setoyama, Dohyun Han, Jingwen Tian, Ho Yeop Lee, Hyun Suk Shin, Ha Thi Nga, Thi Linh Nguyen, Ji Sun Moon, Hyo Ju Jang, Evonne Kim, Seong‐Kyu Choe, Sang Hyeon Ju, Dae Eun Choi, Obin Kwon, Hyon‐Seung Yi

“…The etiological pathways differ, with aging factors implicated in sarcopenia and a combination of uremic factors, including haemodialysis, contributing to ESRD‐related muscle wasting. …”
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Characteristics of myocardial work during exercise stress echocardiography in healthy adults by Liwei Huang, Liwei Huang, Luwei Ye, Luwei Ye, Hongmei Zhang, Hongmei Zhang, Qingfeng Zhang, Qingfeng Zhang, Geqi Ding, Geqi Ding, Chunmei Li, Chunmei Li, Yan Deng, Yan Deng, Lixue Yin, Lixue Yin, Yi Wang, Yi Wang

“…Previous research has shown that global work efficiency (GWE) decreases following exercise.ObjectivesTo characterize sex-based differences in MW during exercise SE in healthy adults and to explore the factors influencing the decline in GWE post-exercise.MethodsThe study enrolled 200 healthy adults, all of whom underwent echocardiographic assessments both at rest and immediately after completing a symptom-limited treadmill stress test. …”
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Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis by Shuo Liu, Kristen D. Popowski, Christina M. Eckhardt, Weihang Zhang, Junlang Li, Yujia Jing, Dylan Silkstone, Elizabeth Belcher, Megan Cislo, Shiqi Hu, Halle Lutz, Asma Ghodsi, Mengrui Liu, Phuong‐Uyen C. Dinh, Ke Cheng

“…Inhaled miR‐30a and Exo consistently lead to improved pulmonary function across six consecutive pulmonary function tests and promote de‐differentiation of profibrotic myofibroblasts. …”
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Developing a predictive model for neoadjuvant therapy in HER2 overexpression breast cancer using multi-parameter MRI radiomics: two-center retrospective study by Lingling Wang, Jingru Yang, Li Yang, Yun Zhu, Xiaomin Tang, Xinyu Cao, Wenbo Kang, Haitao Sun, Zongyu Xie, Zongyu Xie, Zongyu Xie

“…Model performance was evaluated using AUC, DeLong test, calibration curves, and decision curve analysis (DCA).ResultsIn this study, multivariate analysis identified key predictive clinical factors for pCR, including Ki-67 increment index and tumor morphology. …”
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Experimental Study on Desorption Characteristics of Coalbed Methane under Variable Loading and Temperature in Deep and High Geothermal Mine by Haifeng Ma, Lingjie Wang, Housheng Jia, Jucai Chang, YingMing Li, Xiangyang Zhang, Zuxiang Hu, Zhiqiang Yin

“…In order to study the desorption characteristics of coalbed methane under different loading and temperature conditions, the desorption tests at different deformation stages of coal containing methane were carried out in the process of loading-adsorption-desorption-reloading until the coal sample was destroyed by using the seepage-adsorption-desorption test system on coal and rock mass, and the test programs were different combinations of gas pressure 1.2 MPa, two kinds of confining pressure, and three kinds of temperature. …”
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Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways. by Charlie W Lees, William J Zacharias, Mark Tremelling, Colin L Noble, Elaine R Nimmo, Albert Tenesa, Jennine Cornelius, Leif Torkvist, John Kao, Susan Farrington, Hazel E Drummond, Gwo-Tzer Ho, Ian D R Arnott, Henry D Appelman, Lauri Diehl, Harry Campbell, Malcolm G Dunlop, Miles Parkes, Sarah E M Howie, Deborah L Gumucio, Jack Satsangi

“…Since this IBD-associated variant encodes a GLI1 protein with reduced function and our expression studies demonstrated down-regulation of the HH response in IBD, we tested whether mice with reduced Gli1 activity demonstrate increased susceptibility to chemically induced colitis.…”
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Impact of csDMARDs vs. b/tsDMARDs on the Prognosis of Rheumatoid Arthritis-Associated Interstitial Lung Disease: A Multicenter, Retrospective Study by Kyung-Ann Lee, Bo Young Kim, Sung Soo Kim, Yun Hong Cheon, Sang-Hyon Kim, Jae Hyun Jung, Geun-Tae Kim, Jin-Wuk Hur, Myeung-Su Lee, Chong Hyuk Chung, Yun Sung Kim, Seung-Jae Hong, Hae-Rim Kim, Hong Ki Min, Se Hee Kim, Su-Jin Moon, Sung Hae Chang, Soojin Im, Bo Da Nam, Hyun-Sook Kim

“…This study aimed to investigate the effects of csDMARDs and b/tsDMARDs on RA-ILD progression and prognosis based on pulmonary function tests (PFTs), high-resolution computed tomography (HRCT), and symptom changes. …”
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Tight interconnection and multi-level control of Arabidopsis MYB44 in MAPK cascade signalling. by Helene Persak, Andrea Pitzschke

“…Its in vivo interaction with the nuclear sub-pools of both MPK3 and MKK4 renders MYB44 the first plant transcription factor to have a second function as putative MAPK cascade scaffolding protein.…”
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Perfluorohexane Sulfonic Acid Disrupts the Immune Microenvironment for Spermatogenesis by Damaging the Structure of the Blood‐Testis Barrier in Mice by Yan Zhang, Mingxue Shu, Shilin Shan, Huiying Liu, Yucheng Zhang, Chenyang Song, Qiaoqiao Xu, Yun Fan, Chuncheng Lu

“…In summary, the results of this study suggest that in the testes of PFHxS‐treated mice, inflammatory factors disrupt the mitochondrial function and metabolic profiles and hinder the progress of gene transcription through histone Kac, ultimately causing sperm dysfunction.…”
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Correlation Analysis of Clinical Outcomes for Patients With Coronal Pelvic Obliquity After Total Hip Arthroplasty in Direct Anterior Approach by Tianyu Lai, Kaiwei Shen, Yiping Lan, Jinhua Chen, Eryou Feng

“…The Harris score was used to evaluate hip function before and after surgery. Repeated measure ANOVAs were applied to compare multiple time points within groups, while the Fisher's LSD test was used for pairwise comparisons between the means of multiple samples across groups. …”
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Influence of a structured, 1-year-long dietary intervention regarding body composition and cardiovascular risk (ARCTIC) in coeliac disease: a protocol of a multicentre randomised c... by Zsolt Szakács, Nelli Farkas, Judit Bajor, Nándor Faluhelyi, Krisztina Hagymási, Zsófia Vereczkei, Míra Zsófia Peresztegi, Klára Lemes, Sarolta Dakó, Eszter Dakó, Szilvia Lada, Gábor Szekeres, Gyula Pásztor, Gabriella Pár, Emese Mezősi

“…We planned a randomised controlled trial to test the effect of a group-based, structured, 1-year, advanced dietary education, per the proposal of a Mediterranean diet vs standard of care, regarding the most relevant CV risk factors (eg, metabolic parameters and body composition) in CD patients.Methods and analysis Randomisation will occur after the baseline dietary education and interview in a 1:1 allocation ratio. …”
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An analysis of the role of non-governmental organizations in improving the urban management system from the perspective of the citizens of the metropolis of Tehran by sirous rahimzadeh sisibig, alireza shichaslami, Kianoosh zakerhaghighi

“…In the framework of confirmatory factor analysis, comparison of explanatory variance by six factors showed that social, environmental, functional, physical, economic and institutional factors have the highest variance in explaining the role of factors in the urban management system of Tehran. …”
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Association of SNPs in carbohydrate metabolism genes with insulin resistance indicators in the Mexican population by Andrea Méndez-García, Adriana Aguilar-Galarza, Willebaldo García-Muñoz, Juan Brandon Araujo-Mendoza, Teresa García-Gasca, Miriam Aracely Anaya-Loyola, Aarón Kuri-García, Nerina Veyna-Salazar, Lorenza Haddad-Talancón, Ma. de Lourdes Anzures-Cortés, Ulisses Moreno-Celis, Víctor Manuel Rodríguez-García

“…However, the specific contributions of these genetic factors in young Mexicans remain poorly characterized. …”
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Genome analysis of colistin-resistant Salmonella isolates from human sources in Guizhou of southwestern China, 2019–2023 by Jingtong Wu, Yongxian Wen, Lv You, Xiaoyu Wei, Xiaoyu Wei, Junhua Wang, Ge Zhu, Shijun Li

“…The majority of CL-R isolates contained the virulence factor spvB and a notable diversity in other virulence factors with varied functions. …”
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Protocol for an outcome assessor-blinded pilot randomised controlled trial of an ion-exchange water softener for the prevention of atopic eczema in neonates, with an embedded mecha... by Joanne R Chalmers, Sanja Kezic, Zarif K Jabbar-Lopez, Nikeeta Gurung, Danielle Greenblatt, Annette Briley, Kim Suzanne Thomas, Tony Frost, John E A Common, Heidi H Kong, Julie A Segre, Simon Danby, Michael J Cork, Janet L Peacock, Carsten Flohr

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Lignin as a Bioactive Additive in Chlorzoxazone-Loaded Pharmaceutical Tablets by Andreea Creteanu, Gabriela Lisa, Cornelia Vasile, Maria-Cristina Popescu, Daniela Pamfil, Alina-Diana Panainte, Gladiola Tantaru, Madalina-Alexandra Vlad, Claudiu N. Lungu

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Ascites of unknown origin in infant: a rare case report by Rendi Aji Prihaningtyas, Bagus Setyoboedi, Faradila Khoirun Nisa Hakim, Sjamsul Arief

“…Laboratory parameter measurement revealed increased liver function test, hypoalbuminemia, and prolonged coagulation factor. …”
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Predicting 30-Day Venous Thromboembolism Following Total Joint Arthroplasty: Adjusting for Trends in Annual Length of Stay by Johnathan R. Lex, MBChB, MASc, Robert Koucheki, MD, MEng, Aazad Abbas, MD, Jesse I. Wolfstadt, MD, MSc, FRCSC, FAAOS, Alexander S. McLawhorn, MD, MBA, Bheeshma Ravi, MD, PhD, FRCSC

“…The logistic regression model trained on all data with a balanced loss scoring function performed the best (area under the curve = 0.600). …”
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The impact of 24-hour sleep deprivation on cognition and inflammatory response in anesthesiologists and nurses in operating rooms by Tao Ma, Long Feng, Guan-Hua Li, Xiu-Yan Sun, Yang Chu, Wen-Hui Zhao, Shuai Feng, Hao Zhang, Wei Wang

“…Cognitive functions were assessed using the Trail Making Test and the Stroop Color-Word Test. …”
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How common is hypothyroidism after external radiotherapy to neck in head and neck cancer patients? by Nirmala Srikantia, Karthik S Rishi, M G Janaki, Ramesh S Bilimagga, Arul Ponni, A G Rajeev, Kirthi Kaushik, Mala Dharmalingam

“…Recognizing hypothyroidism (clinical or subclinical) early and treating it prevents associated complications. Hence, thyroid function tests should be made routine during follow-up.…”
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