CHANGE OF ORAL LIQUID PROPERTIES UNDER TREATMENTS DEVELOPED INFLAMMATION OF PERIODONTAL TISSUES IN PATIENTS CONSTRUCTIONS WITH FIXED DENTURE IN MOUTH CAVITY DYNAMICS by O. Petrushanko, S. Hermanchuk

“…Oral liquid integrate external and internal factors of the pathogenesis of chronic catarrhal gingivitis. …”
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THE DEVELOPMENT OF SCIENCE AND THE FATE OF A SCIENTIST (FOLLOWING GENETICS) by Jonas Rubikas

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Incidence and Predictors of Postoperative Delirium in Patients Undergoing Elective Hip and Knee Arthroplasty: A Prospective Observational Study by James Paul, Amir Hamid, Heung Kan Ma, Thomas Kim, Lehana Thabane, Thuva Vanniyasingam

“…<b>Methods</b>: This prospective observational study recruited patients (n = 978) with normal cognitive function presenting for elective primary hip or knee arthroplasty at a single tertiary academic center. …”
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Adaptive Stochastic Approach for Evaluating Service Level Using a (SIM-ESL) Module Developed for Optimizing Product Availability and Order Accuracy by Aufy Samah A., Jabbar Rasha, Shiaa Waad Q.

“…While, Taguchi method used to optimize and determine relative magnitude of the effect of various factors and their interactive. The obtained results were proved and reliability in determining the customer satisfaction score in real-world. …”
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The role and mechanism of long non-coding RNA ARID2-IR in chronic glomerulonephritis by ZHANG Ai-ping, HE Fang, SHE Kai-ru

“…Objective To investigate the relationship between LncRNA ARID2-IR and renal function in patients with chronic glomerulonephritis(CGN)and its mechanism.Methods A total of 52 CGN patients(CGN group)and 45 healthy adults(control group)were enrolled in the study.General information(age,gender,blood pressure,body mass index,etc.)was collected.Blood urea nitrogen(BUN)and serum creatinine(Scr)were tested.Target gene prediction was performed through the Starbase database,and KEGG pathway enrichment analysis was performed by Tbtools software.Real-time fluorescent quantitative PCR was used to detect the expression of LncRNA ARID2-IR and target genes.With ROC curve,the diagnostic value of LncRNA ARID2-IR and target genes for CGN was analyzed,and the influencing factors of CGN were analyzed by Logistic regression model.Results Systolic blood pressure,diastolic blood pressure,BUN and Scr in the CGN group were significantly higher than those in the control group(P<0.05).The expression of LncRNA ARID2-IR in the CGN group was significantly higher than that in the control group(P<0.05).LncRNA ARID2-IR expression was significantly correlated with BUN(r=0.225,P<0.05)and Scr(r=0.266,P<0.05),respectively.Target gene prediction showed that LncRNA ARID2-IR had 88 target genes in total,and the top 5 target genes in the score ranking for matching with LncRNA ARID2-IR were IFT80,IGHG4,RLBP1,ANKRD27 and TSPAN6,of which IFT80 and RLBP1 in the CGN group had much higher expression levels than those in the control group(P<0.05).The ROC curve showed that the AUCs of LncRNA ARID2-IR,IFT80 and RLBP1 were 0.783,0.821 and 0.738,respectively,which was of diagnostic significance for CGN.Logistic regression analysis showed that elevated levels of LncRNA ARID2-IR(OR=4.754,P=0.021),IFT80(OR=3.518,P=0.001)and RLBP1(OR=4.718,P=0.021)increased CGN risk.Conclusions Up-regulation of LncRNA ARID2-IR expression plays an important role in CGN.LncRNA ARID2-IR may be a new target for CGN control.…”
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Correlations of strength, proprioception, and dynamic balance to the Cumberland Ankle Instability Tool Score among patients with chronic ankle instability: a cross-sectional study by Dehao Peng, Huiru Tang, Min Mao, Qipeng Song, Dewei Mao, Jiangna Wang, Wei Sun

“…This provides data support for targeted ankle neuromuscular function rehabilitation training for patients. Trial registration Chinese Clinical Trial Registry ChiCTR2100044089. …”
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THE DEVELOPMENT OF SCIENCE AND THE FATE OF A SCIENTIST (FOLLOWING GENETICS) by Jonas Rubikas

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The current role of pentafecta outcomes in open and laparoscopic partial nephrectomy for localized renal tumors by Aly M. Abdel-Karim, Omar A. Bakheet, Gamal Alsagheer, Mostafa AbdelRazek

“…The present study aimed to identify predictive factors associated with the achievement of pentafecta outcomes following PN. …”
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Experimental application results of mesenchymal stem cell microvesicles in the mouse model of acute renal failure by I. P. Ivanova, G. V. Seledtsova, V. I. Seledtsov, T. S. Khabalova, A. B. Dorzhieva

“…They can be a source of cytokines, anti- apoptotic and growth stimulating factors. In addition, MVs carry out transport of mRNA, miRNA, and signal proteins into damaged tissues. …”
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Human Placental Extract as a Promising Epidural Therapy for Lumbar Spinal Stenosis: Enhancing Axonal Plasticity and Mitigating Pain and Inflammation in a Rat Model by Jin Young Hong, Hyun Kim, Wan‐Jin Jeon, Changhwan Yeo, Junseon Lee, Hyunseong Kim, Yoon Jae Lee, In‐Hyuk Ha

“…Additionally, the 3D spinal cord exhibited increased serotonergic axons and upregulated expression of genes related to axonal growth and neurotrophic factors (Nefh, Ngf, Bdnf, Gap43). Conclusions Our findings suggest that repeated epidural injections of human placental extract in LSS rats can improve locomotor function. …”
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Analysis of capacity load and nutritional status of peritoneal dialysis patients with diabetic kidney disease and non diabetic kidney disease by BAI Tian-li, YU Qing, ZHU Bing-bing, WANG Yun-man, WANG Hao

“…Objective To analyze the changes of capacity load and nutritional status of diabetic kidney disease(DKD) and non diabetic kidney disease(NDKD) patients within one year of peritoneal dialysis,so as to provide theoretical basis for better clinical intervention.Methods The general data of 116 patients(42 in DKD group and 74 in NDKD group) who received peritoneal dialysis(PD) in our hospital from January 2010 to August 2019 were collected by retrospective analysis.The indexes of laboratory tests such as liver function and brain natriuretic peptide were measured at baseline and 1,3,6,12 months after PD;and clinical evaluation indexes such as peritoneal dialysis mode,dialysate concentration and dosage,24-hour ultrafiltration volume,24-hour urine volume,blood pressure,edema,and types of antihypertensive drugs were compared within a group and between groups by statistical tools,so as to clarify PD efficacy and the efficacy difference between the two groups.Results The dosage of peritoneal dialysis in the DKD group was higher than that in NDKD group(P<0.05) at various time points one month after dialysis.There was no significant difference in 24-hour peritoneal ultrafiltration volume(P>0.05),but 24-hour urine volume in the DKD group was less than that in the NDKD group(P<0.05),the incidence of edemat was higher than that of NDKD group(P<0.05) after 12 months of dialysis,but there was no significant difference in blood pressure level and types of antihypertensive drugs taken(P>0.05).After treatment,serum albumin(Alb) in the study population was lower than that at baseline(P<0.05),and Alb in the DKD group was lower than that in the NDKD group(P<0.05) from baseline to six months after dialysis.There was no significant difference between the two groups after six months(P>0.05).Conclusions The nutritional status in the DKD group is worse than that in the NDKD group at the early stage of dialysis.After 12 months of dialysis,the patients in the DKD group are in a higher capacity load condition than those in the NDKD group.After 1 month of dialysis,the DKD group needs a bigger peritoneal dialysis dosage than the NDKD group.This suggests that clinicians should make a reasonable peritoneal dialysis plan according to their body fluid retention,blood pressure and other factors to maintain an appropriate blood volume and protect residual renal functions.…”
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Cerebral perfusion and gray matter volume alterations associated with cognitive impairment in metabolic syndrome with cerebral small vessel disease by Han Liu, Han Liu, Wenhui Zheng, Jie Geng, Jie Geng, Xia Zhou, Yu Xia, Yan Liu, Gang Zhang, Gang Zhang, Xiaoqun Zhu, Daping Lv, Daping Lv, Zhongwu Sun

“…Partial correlation analysis revealed that CBF and GMV in the frontotemporal lobe were strongly associated with overall cognitive function, executive function, and language function in the MetS-CSVD group. …”
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Novel application of CHUANG BI FU biologic protein sponge in promoting peripheral nerve injury repair by regulating vascular regeneration by Yunhao Cai, Jiahao Liu, Renwei Han, Zizhao Ma, Kaihang Yu, Ping Wu, Xiaokun Li, Zhouguang Wang, Jian Wang

“…Methods This study used a 3.5-mm nerve defect model in mice, and wrap CHUANG BI FU around the nerve defect site, connecting the distal and proximal ends of the damaged nerve without suturing the nerve. The repair function of the nerve by the wound was tested by detecting mouse footprints, electrophysiology, NF200 staining, CD31 staining, and gastrocnemius muscle Masson staining. …”
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Thyroid Dysfunction and COVID-19 Disease Severity Among Hospitalised COVID-19 Patients: A Multicentre Study by Dr Chee Peng Hor, Dr. Rabeah Md Zuki, Dr. Peng Shyan Wong, Dr. Joo Thye Cheng, Dr. Joelynn Shen Wei Lim, Dr. Chee Hoe Lim, Dr. Min Han Cheng, Dr. Juan Gang Tan, Dr. Jolene Goh, Dr. Je Vin Teh, Dr. Hooi Xian Wang, Dr. Shanty Velaiutham, Dr. Nurain Mohd Noor

“…About 39.7% had normal thyroid tests and 8.9% were found positive for anti-TPO regardless of their thyroid function status. …”
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Associations between milk infrared-predicted plasma biomarkers of stress resilience and fertility in dairy cattle: Insights for enhancing breeding programs and herd management by Alessio Cecchinato, Hugo Toledo-Alvarado, Lucio Flavio Macedo Mota, Vittoria Bisutti, Erminio Trevisi, Riccardo Negrini, Sara Pegolo, Stefano Schiavon, Luigi Gallo, Giovanni Bittante, Diana Giannuzzi

“…The 2 databases were merged according to the milk test day (and thus, the MIR spectrum) closest to the date of insemination. …”
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Increased Degenerative Biomarkers in Females with Patellofemoral Pain: A Cross-Sectional Analysis with 6-Month Progression by Lori A. Bolgla, Tiana V. Curry-McCoy, Maya Giddens, Madelyn Overton, Bryaunna Barrera, Jasmine Crockett, Monte Hunter

“…Background/Objectives: Patellofemoral pain (PFP) is considered a risk factor for knee osteoarthritis (OA) onset. The purpose of this study was to compare degenerative biomarkers in females with and without PFP and to determine changes in these levels, along with pain and function, over 6 months. …”
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The effect of rs776746 polymorphism in the <i>CYP3A5</i> gene on heart rate when using bisoprolol in patients with acute coronary syndrome by V. A. Shumkov, K. A. Zagorodnikova, S. A. Boldueva, A. A. Murzina

“…Taking into account the close to significant differences in glomerular filtration rate (GFR) in patients in the groups with the studied genetic variants, and the known eliminating role of the kidneys for bisoprolol, a linear regression model was built with the inclusion of factors that could affect the dose of bisoprolol: GFR, functional class of chronic heart failure, gender, age, number of simultaneously assigned CYP3A5 substrates. …”
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Revisión narrativa y desarrollo de un programa de intervención para la disminución de los efectos del Alzheimer a través de la práctica del Surf en Personas Mayores (Narrative rev... by Mateo Real Pérez, Cristina Robles Rodríguez, Jesús Gustavo Ponce González

“…La enfermedad de Alzheimer (EA) y otros trastornos demenciales son factores importantes a tener en cuenta en los índices de morbilidad y mortalidad en la sociedad actual. …”
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Enhancing prehension strength and dexterity through cross-education effects in the elderly by Da Won Park, Yang Sun Park, Kyung Koh, Hyun Joon Kwon, Sang Hwa Lee, Jaebum Park, Jae Kun Shim

“…Maximum Grasping Force (MGF), Jebsen–Taylor hand function test, and Purdue Pegboard test were measured. …”
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Transcriptome-wide analysis reveals potential roles of CFD and ANGPTL4 in fibroblasts regulating B cell lineage for extracellular matrix-driven clustering and novel avenues for imm... by Hongwei Wang, Yu-nan Zhu, Sifan Zhang, Kexin Liu, Rong Huang, Zhigao Li, Lan Mei, Yingpu Li

“…However, the compositional patterns of ECM in breast cancer and their underlying biological functions remain elusive. Methods Transcriptome and genome data of breast cancer patients from TCGA database was downloaded. …”
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