Health status, respiratory symptom and dyspnea trajectories in subjects with chronic obstructive pulmonary disease: a seven-year observation in clinical practice by Koichi Nishimura, Masaaki Kusunose, Ayumi Shibayama, Kazuhito Nakayasu

“…Participants underwent pulmonary function tests and completed four PRO measures: St. …”
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Hepatic enzyme alterations as prognostic markers in neonates with hypoxic-ischemic encephalopathy: A hospital-based prospective cohort study. by Dr . Eaka Mahesh, Dr. Ragini Mutukulla, Dr . Durgesh Velupula, Dr. Bindhu Vechangi

“…HIE staging was performed using the modified Sarnat and Sarnat criteria. Liver function tests, including serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), and alkaline phosphatase (ALP), were measured on Days 1 and 3. …”
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Egg freshness during storage: the effect of laying hen age and shelf life prediction using a novel hybrid modeling method by Yifeng Lu, Jing Li, Zihao He, Linyun Chen, Huixin Tian, Chen Xu, Xinglian Xu, Minyi Han

“…The tuning process of hyperparameters such as learning rate, training function, and transfer function was presented in detail. …”
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An Interdisciplinary Ecosystem for the Prevention of Cardiotoxicity in Older Patients With Breast Cancer: Protocol for a Prospective and Multicentric Study by Gaia Giulia Angela Sacco, Ketti Mazzocco, Anastasia Constantinidou, Andri Papakonstantinou, Davide Mauri, Grigorios Kalliatakis, Manolis Tsiknakis, Domen Ribnikar, Dorothea Tsekoura, Valantis Aidarinis, Kalliopi Keramida, Panagiotis Oikonomopoulos, Athos Antoniades, Cameron Brown, Federica Rizzi, Anca Bucur, Elsa Pacella, Georgia Karanasiou, Daniela Cardinale, Carlo Cipolla, Elisabetta Munzone, Dimitrios Fotiadis, Giuseppe Curigliano, Gabriella Pravettoni

“…In total, 750 older patients with breast cancer (aged ≥60 years) are assigned to either the standard practice or enhanced monitoring group, with only patients in the latter receiving access to eHealth psychological, behavioral, and functional interventions implemented on the CARDIOCARE eHealtHeart app. …”
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Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo by Witold N. Nowak, Hevidar Taha, Joanna Markiewicz, Neli Kachamakova-Trojanowska, Jacek Stępniewski, Damian Klóska, Urszula Florczyk-Soluch, Rafał Niżankowski, Marzena Frołow, Zbigniew Walter, Józef Dulak, Alicja Józkowicz

“…They home to sites of neovascularization and contribute to angiogenesis by production of paracrine factors. The number and function of proangiogenic cells are impaired in patients with diabetes or cardiovascular diseases. …”
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Genome-Wide Identification and Expression Analysis of Pseudo-Response Regulators (PRRs) in the Tea Plant <i>Camellia sinensis</i> (L.) O. Kuntze by Lili Ye, Huaqian Xue, Nana Li, Meng Ye, Jianyan Huang, Xinchao Wang, Juan Wu, Changqing Ding

“…This study presents the first comprehensive analysis of <i>CsPRRs</i> in the tea plant, providing vital information for further elucidation of <i>CsPRR</i> functions. It also suggests that tissue type and photoperiod conditions should be taken into consideration when conducting gene function studies in the tea plant.…”
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Shaoyao Gancao decoction alleviates paclitaxel-induced cognitive impairment by activating PTEN/PI3K/AKT pathway to inhibit NETs formation by Xu Ying, Su Yue, Hu Yuwen, Li Xiang, Zhou Ziyan, Yuan Ningning, Ji Xiaowei, Jiang Ruoyu, Wang Wenzhu, Zhang Yafeng, Zhai Guojie, Cheng Xiaolan

“…Secondly, PICI mice model was established, and the neuroprotective effects of SGD on PICI mice were eveluated by using new object recognition, Morris water maze test and TUNEL staining. The impact of SGD on inflammatory factors, microglia activation and NETs formation were also studied by ELISA and immunofluorescence. …”
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Analyzing power errors in the optical pumping system of atomic spin comagnetometers by Jiale QUAN, Ye LIU, Longyan MA, Wenfeng FAN, Wei QUAN

“…A significant challenge in the SERF comagnetometers performance is power errors in optical pumping systems, which affect two critical operational aspects: scale factor and zero-bias stability. The scale factor determines the relationship between the input signal and the comagnetometer output, whereas zero-bias stability refers to the system’s long-term stability in the absence of an input signal. …”
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Effectiveness of isoniazid preventive treatment among patients on antiretroviral treatment in Southeast Nigeria: A retrospective cohort study by Chukwuma David Umeokonkwo, Bello Segun, Patrick Nguku, Muhammad Shakir Balogun, Peter Nsubuga, Lilian Bulage, Adanna Anthonia Umeokonkwo, Olufunmilayo Ibitola Fawole

“…There was no difference in the Kaplan-Meier survival functions between the exposed and unexposed (log-rank test χ2 =1.58, p=0.209). …”
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PediaTrac V.3.0 protocol: a prospective, longitudinal study of the development and validation of a web-based tool to measure and track infant and toddler development from birth thr... by H Gerry Taylor, Renee Lajiness-O'Neill, Seth Warschausky, Alissa Huth-Bocks, Judith Brooks, Angela Lukomski, Trivellore Eachambadi Raghunathan, Patricia Berglund, Angela D Staples, Laszlo Erdodi, Stephen Schilling

“…Participants also will complete legacy (ie, established) measures of development and caregiver health and functioning, used to provide evidence for construct (discriminant) validity. …”
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Determination of specific gas exchange rates in microperforated modified atmosphere packaging: effect of perforation size and gas concentration by Gergő Szabó, Zsuzsanna Horváth-Mezőfi, Lien Le Phuong Nguyen, Stephen Tully, Zoltán Gillay, Christopher Brian Watkins, Tamás Zsom, Géza Hitka

“…Gas exchange rates were calculated using a polynomial function based on the concentration differences of the gases. …”
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The role of melatonin in the regulation of the immune system and reproductive health: mechanisms and prospects for clinical application by M. M. Zhelavskyi, S. P. Kernychnyi, O. Ya. Dmytriv, T. V. Betlinska

“…Beyond its well-known function in circadian rhythm regulation, melatonin exerts potent antioxidant, anti-inflammatory, and immunomodulatory effects. …”
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Effect of Post-Acute Kidney Injury Use of Renin-Angiotensin Inhibitors on Long-term Mortality and Major Adverse Kidney Events: A 5-year Retrospective Observational Cohort Study by Byorn W.L. Tan, Bryce W.Q. Tan, K. Akalya, Wei-Zhen Hong, Yi Da, Sanmay Low, Wan-Ying Ng, Horng-Ruey Chua

“…Rationale &amp; Objective: Acute kidney injury (AKI) is common in hospitalized adults and a risk factor for chronic kidney disease and mortality. The effect of angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs) post-AKI on mortality and long-term kidney function remains unclear. …”
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Genomic and molecular characterization of a ceftazidime-avibactam resistant Klebsiella pneumoniae strain isolated from a Chinese tertiary hospital by Yanye Tu, Hui Gao, Feng Wang, Rongqing Zhao, Shiyong Chen, Yanzi Chang, Hong Li

“…Genomic characterization revealed the strain belonged to capsular type KL16 and harbored multiple resistance determinants, including bla CTX−M−65, bla SHV−103 and bla TEM−1, along with iron acquisition-associated virulence factors (iutA, entABCDEF, and iroN). Plasmid analysis identified three distinct plasmids, among which an IncX3-type plasmid carrying bla NDM−5 was confirmed, while the functional characteristics of the remaining two plasmids require further investigation. …”
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Genetics of catatonia: a systematic review of case reports and a gene pathway analysis by Mylene Moyal, Anton Iftimovici, Wafa Ghoul, Marion Plaze, Boris Chaumette

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Patient experience in retinitis pigmentosa and Choroideremia– a concept elicitation study in 17 patients based on qualitative interviews by Elke Rometsch, Per-Olof Thuresson, Noémie Hurst, Eckhart Eule, Isabel Bachmeier, Benoit Blanchard, José-Alain Sahel, Isabelle Audo

“…These impacts were often exacerbated by environmental factors. For instance, all participants reported this for navigation. …”
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Evaluating the value of machine learning models for predicting hematoma expansion in acute spontaneous intracerebral hemorrhage based on CT imaging features of hematomas and surrou... by Tianyu Yang, Tianyu Yang, Zhen Zhao, Yan Gu, Shengkai Yang, Yonggang Zhang, Lei Li, Ting Wang, Zhongchang Miao

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CMV Retinitis in the Context of SARS-CoV-2 Infection: A Case Study and Comprehensive Review of Viral Interactions by Emil Robert Stoicescu, Laura Andreea Ghenciu, Roxana Iacob, Adina Iuliana Ardelean, Ecaterina Dăescu, Ovidiu Alin Hațegan, Diana Manolescu, Emanuela Tudorache, Casiana Boru, Mirabela Dima

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Monitoring Abiotic Stressors in Rainfed Vineyards Involves Combining UAV and Field Monitoring Techniques to Enhance Precision Management by Federico Valerio Moresi, Pasquale Cirigliano, Andrea Rengo, Elena Brunori, Rita Biasi, Giuseppe Scarascia Mugnozza, Mauro Maesano

“…This study identifies significant soil heterogeneity within the tested vineyard, affecting water retention, nutrient availability, and vine water stress. …”
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Screening 215 Lentil Genotypes under Salinity Stress During the Seedling Stage in Greenhouse Conditions by Ahmad Nezami, jafar Nabati, Mohammad Kafi, Elahe Boroumand Rezazadeh

“…After conducting the data normality test and homogeneity of variances, the means were compared using the Least Significant Difference (LSD) test at a 5% probability level. …”
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