Early weaning-induced intestinal barrier dysfunction associates with Th17/Treg imbalance in squabs by Qianqian Xu, Zhiying Luo, Tianliang Ling, Wenyan Zhao, Xinyang Dong

“…Mantel tests showed that the changes of factors related to the differentiation of Th17/Treg cell subsets were significantly correlated with the diamine oxidase, endotoxin level, and the CDLN1 mRNA expression. …”
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Preliminary effectiveness of social prescription and virtual patient information in increasing tertiary prevention among cancer patients (ESPRIT): protocol for a single-centre, ran... by Karen Steindorf, Michael Koller, Michael Leitzmann, Wolfgang Herr, Daniel Heudobler, Lisa Boyer, Anne Herrmann, Tobias Pukrop, Christine Bernardi, Sabine Einhell

“…The analysis of secondary endpoints will include appropriate statistical methods such as the χ2 test of independence or linear regression models, which will be used to analyse secondary endpoints and to investigate factors influencing preliminary effectiveness.Ethics and dissemination This trial has been approved by the ethics committee of the University of Regensburg (reference: 23-3317-101). …”
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Sodium-Dependent Glucose Transporter-2 Inhibitor Enhances the Hypotensive Effect of Renal Denervation by Inhibiting Sympathetic Activity and Inflammatory Reaction by Hao Zhang, Zhuqing Li, Wei Cai, Yanxin Wang, Jiaxin Feng, Xuemei Yin, Qi Li, Ning Yang, Chengzhi Lu, Yuming Li

“…Additionally, the proportions of inflammatory mononuclear cell subsets and the levels of inflammatory factors improved. Although DAPA reduced inflammation and sympathetic nerve overexcitation alone, it could not completely reverse blood pressure (BP) or cardiac function. …”
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Identification of genetic mechanisms of non-isolated auditory neuropathy with various phenotypes in Chinese families by Yang Cao, Xiaolong Zhang, Lan Lan, Danyang Li, Jin Li, Linyi Xie, Fen Xiong, Lan Yu, Xiaonan Wu, Hongyang Wang, Qiuju Wang

“…Genes associated with non-isolated AN were summarized from prior reports, and functional enrichment analysis was conducted using Gene Ontology databases. …”
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Refractory angina in women with ischemia and no obstructive coronary artery disease — A report from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD... by Judy M. Luu, Janet Wei, Chrisandra Shufelt, Anum Asif, Benita Tjoe, Galen Cook-Wiens, Eileen M. Handberg, Puja K. Mehta, Jenna Maughan, Daniel S. Berman, Louise E.J. Thomson, Carl J. Pepine, C. Noel Bairey Merz

“…In a pre-defined subgroup (n = 198) with repeat cardiac magnetic resonance imaging (CMRI) at 1-year, we investigated severity of angina (Seattle Angina Questionnaire-7) in relation to risk factors, baseline invasive coronary function testing, and CMRI parameters. …”
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Solving UAV 3D Path Planning Based on the Improved Lemur Optimizer Algorithm by Haijun Liang, Wenhai Hu, Ke Gong, Jie Dai, Lifei Wang

“…A Gaussian function model is used to simulate the mountain environment, and a mathematical model for UAV flight is established based on constraints and objective functions. …”
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Wheat disease recognition method based on the SC-ConvNeXt network model by Tianliang Dong, Xiao Ma, Bin Huang, Wenyu Zhong, Qingan Han, Qinghai Wu, You Tang

“…Subsequently, the CBAM attention module is integrated into ConvNeXt-T to enhance the model’s feature extraction and generalization capabilities in complex backgrounds, and each attention module’s loss function is improved with a LeakyReLU activation function to prevent neuron deactivation when inputs are negative. …”
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Semaglutide: an emerging treatment option for patients with obesity related HFpEF by Sanya Ashraf Khaskheli, Najaf Ahmed Rajpar

“…Initially, the use of Semaglutide, a glucagon-like peptide-1 receptor agonist, showed favourable outcomes in cardiac function of mice. This study observed that weight loss achieved using Semaglutide was met with improvements in several factors associated with HFpEF (reduced LV hypertrophy and fibrosis, improved diastolic function, reduced lung congestion and improved exercise capacity) as compared to weight loss achieved through simple dietary means3. …”
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Heritability of cardiovascular and personality traits in 6,148 Sardinians. by Giuseppe Pilia, Wei-Min Chen, Angelo Scuteri, Marco Orrú, Giuseppe Albai, Mariano Dei, Sandra Lai, Gianluca Usala, Monica Lai, Paola Loi, Cinzia Mameli, Loredana Vacca, Manila Deiana, Nazario Olla, Marco Masala, Antonio Cao, Samer S Najjar, Antonio Terracciano, Timur Nedorezov, Alexei Sharov, Alan B Zonderman, Gonçalo R Abecasis, Paul Costa, Edward Lakatta, David Schlessinger

“…On average, genetic effects explained 40% of the variance for 38 blood tests, 51% for five anthropometric measures, 25% for 20 measures of cardiovascular function, and 19% for 35 personality traits. …”
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The efficacy and safety of fecal microbiota transplantation in the treatment of sarcopenia: a retrospective study by Bo Yang, Xinhui Li, Jiahui Wang, Yue Xu, Le Wang, Zhifeng Wu, Di Zhao, Long Huang, Ning Li, Qiyi Chen, Zhongchen Liu

“…Muscle mass was measured using bioelectrical impedance analysis, while muscle function was assessed through grip strength and the five-time sit-to-stand test. …”
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Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages. by Steven J Conrad, Tahseen Raza, Erich A Peterson, Jason Liem, Richard Connor, Bernice Nounamo, Martin Cannon, Jia Liu

“…The M062R gene product is essential for MYXV infection in almost all cells tested from different mammalian species and specifically inhibits the function of host Sterile α Motif Domain-containing 9 (SAMD9), as M062R-null (ΔM062R) MYXV causes abortive infection in a SAMD9-dependent manner. …”
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Predicting poor self-management behaviors in adults with newly diagnosed COPD: based on the information-motivation-behavioral skills model by Xiaomei Chen, Jia Liu, Yuxuan He, Li Wei, Menghui Deng, Rui Zhang, Huiqin Song, Yanni Yang

“…The AUC of the validation cohort was 0.898 and the Hosmer-Lemeshow test indicated good model prediction. Conclusions The risk prediction model based on IMB model and a nomogram including 3 easily available prediction factors (cognitive function, patient activation and depression) on poor self-management behaviors for newly diagnosed COPD patients was established, which showed good discrimination, and calibration. …”
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Attitude and knowledge of women about menopause and hormone replacement therapy by Roya Faraji, Maryam Asgharnia, Fatemeh Hosseinzadeh, Seyedeh Fatemeh Dalil heirati, Atefeh Emadi

“…These data were analysed by T test and Chi-square and spss10 software. Results: 32.1% of 277 women had high knowledge about predisposing factors of menopause 60.7%(168) were well informed about menopausal signs ,75.5%(209)were agreed about hormone therapy, between attitude and knowledge of inducing factors ,also attitude and knowledge of menopausal signs were direct correlation(p<0.0001 - P<0.0001). …”
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Ensuring the safety of the surface of calibrated rolled products in the conditions of small-grade wire mill 370/150 OJSC «BSW – Management Company of the Holding «BMC» by I. A. Kovaleva, I. V. Bazuyev, Yu. V. Prybytkov, N. A. Khodosovskaya

“…It is established that the advantage of packaging of rolled products in anticorrosive paper is that it, combining the functions of packaging means and means of preservation, allows you to completely abandon the expensive and time-consuming preservation of metal products with oils and greases. …”
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Software Define Wide Area Network (SDWAN) network optimization analysis on radiolink-fiber optic access media migration by Nugraha Beny, Muslim Muslim, Mega Nur Khotimah, Lukman Medriavin Silalahi, Dhiya Akmal Firdaus, Christ Geofany

“…The test method used in this study is a connectivity test from each remote fortigate located in the branch office. …”
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Evidence of Subsurface Control on the Coevolution of Hillslope Morphology and Runoff Generation by David G. Litwin, Ciaran J. Harman

“…We found that hillslopes were systematically shorter and saturated areas more dynamic at the lower transmissivity site. To test whether these features could be the result of coevolution between topography, hydrological function, and subsurface properties, we estimated all parameters of a coupled groundwater‐landscape evolution model for each site. …”
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Increased thyroxine levels of patients with allergic rhinitis by Violeta Lokaj-Berisha, Besa Gacaferri Lumezi

“…Abstract Allergic rhinitis and asthma are common respiratory conditions with complex etiologies involving genetic, environmental, and physiological factors. In these conditions, the role of thyroid function remains underexplored. …”
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Computer-aided cognitive recovery in patients with cardiovascular diseases by I. V. Tarasova, D. S. Kupriyanova, O. A. Trubnikova, O. L. Barbarash

“…We describe a cognitive training software to stimulate perception, attention, short-term memory, executive functions, speech, and thinking. Baseline neurological examination and neuropsychological testing are mandatory before starting a cognitive recovery. …”
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Differential gene expression analysis identified determinants of cell fate plasticity during radiation-induced regeneration in Drosophila. by Michelle Ledru, Caitlin A Clark, Jeremy Brown, Shilpi Verghese, Sarah Ferrara, Andrew Goodspeed, Tin Tin Su

“…We used here a combination of lineage tracing, FACS-sorting of cells that change fate, genome-wide RNAseq, and functional testing of 42 genes, to identify two key changes that are required cell-autonomously for IR-induced hinge-to-pouch fate change: (1) repression of hinge determinants Wg (Drosophila Wnt1) and conserved zinc-finger transcription factor Zfh2 and (2) upregulation of three ribosome biogenesis factors. …”
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Clinical features and management of eyes with acute retinal necrosis presenting with rhegmatogenous retinal detachment by Jinal Gore, Anup Kelgaonkar, Anamika Patel, Soumyava Basu, Avinash Pathengay

“…Conclusion: ARN with RD at presentation is a unique medical and surgical challenge, wherein good anatomical and functional outcomes could be achieved. The large size of retinitis and delayed presentation were the risk factors associated with poor visual outcomes.…”
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