The NFATC2/Nrf2 cascade regulates spinal cord ischemia-reperfusion injury by controlling inflammation, apoptosis and oxidative stress by Kunbin Li, Liming Lu, Xianli Yao, Zhiyuan Wu, Pingge Sun, Xiaopeng Wen, Xiaoxing Li, Kai Wang, Xiran Yin

“…The oxidative stress was tested by assessing ROS and MDA contents and SOD and GSH-Px activity. …”
Get full text

Does a whole plant conservation gradient exist within a subtropical broadleaved evergreen forest? by Ailian Fan, Ailian Fan, Xue Wang, Xue Wang, Xiaojun Yan, Xiaojun Yan, Tingting Chen, Tingting Chen, Qi Jiang, Qi Jiang, Linqiao Jia, Linqiao Jia, Weiwei Wang, Weiwei Wang, Decheng Xiong, Decheng Xiong, Jinxue Huang, Jinxue Huang, Guangshui Chen, Guangshui Chen

Get full text

Role of BDNF-TrkB signaling pathway in early-life cadmium exposure induced cognitive dysfunction in mice by Yan SHI, Siqi YANG, Yougang WANG, Qiumei WU, Jinquan LI

“…The cadmium content in brain was detected and the learning and memory ability was tested by Y maze and Morris water maze to evaluate cognitive function of offspring mice. …”
Get full text

Three Strategies Enhance the Bionic Coati Optimization Algorithm for Global Optimization and Feature Selection Problems by Qingzheng Cao, Shuqi Yuan, Yi Fang

“…The bionic ABCCOA algorithm was tested on the CEC2020 test functions and engineering problem, achieving an over 90% optimization success rate and faster convergence, confirming its efficiency. …”
Get full text

Monitoring the labor market in the field of preschool education as a tool for forecasting and improving personnel policy by Lyubov N. Dukhanina

“…The following methods were used in the study: online survey, calculation of descriptive statistics, factorial (exploratory) analysis, correlation analysis according to Charles Spearman, Mann-Whitney U-test. Results. The degree of satisfaction of preschool education workers with working conditions was determined, as a result of the analysis of the functional load of educators, the frequency of their performance of certain labor functions was established, additional, redundant and duplicating labor functions of educators were identified, the need of the preschool education system for new qualifications was clarified, factors influencing the passage of advanced training by educators were highlighted. …”
Get full text

Diagnosis and Prognostic Assessment of Drug-Induced Liver Injury: What Are the Outpatient Options? (Review) by E. V. Gantsgorn, A. V. Bozhko, S. V. Yarchenko

“…The initial screening for liver injury and the determination of its severity necessitate taking a comprehensive medication history and conducting standard liver function tests (alanine transaminase, aspartate transaminase, alkaline phosphatase, total bilirubin). …”
Get full text

Rosuvastatin effects on the HDL proteome in hyperlipidemic patients by Vavlukis Ana, Mladenovska Kristina, Davalieva Katarina, Vavlukis Marija, Dimovski Aleksandar

“…The advancements in proteomics have provided a better understanding of the functionality of apolipoproteins and lipoprotein-associated proteins, with the HDL lipoprotein fraction being the most studied. …”
Get full text

L-Malic Acid Descaler for Drinking Water—Physicochemical Analysis and Biological Activity by Teodora Todorova, Krassimir Boydzhiev, Ignat Ignatov, Teodora Petrova Popova, Zhechko Dimitrov, Irina Gotova, Fabio Huether, Alexander Ignat Ignatov, Yordan Georgiev Marinov

“…In conclusion, water treated with L-malic acid descaler possesses antioxidant effects in yeast-cell-based tests, independent of YAP1 transcription factor activity. …”
Get full text

Differences in efficacies of continuous renal replacement therapy and intermittent hemodialysis upon urinary levels of insulin-like growth factor binding protein 7，neutrophil gelat... by Wang Xiang, Zhang Zhi-min, Li Jian-guo, Song Ya-jun

“…Observation group underwent CRRT while control group had IHD. All cardiac function tests were completed and blood biochemical parameters detected during treatment. …”
Get full text

Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence by Ji‐Hua Shi, Wen‐Zhi Guo, Yang Jin, Hua-Peng Zhang, Chun Pang, Jie Li, Pål‐Dag Line, Shui‐Jun Zhang

“…Signal analysis revealed that HER2 functioned through upregulation of β‐catenin and inhibition of SMAD3. …”
Get full text

Analysis of the Impact of Global Oil Prices On GDP (on the Example of the Azerbaijan Republic) by N. S. Ayyubova

“…When forming the VECM model, the hypotheses put forward in the work were tested using econometric tests. The responses of the impulse function to the independent variables of the model were studied by the method of graphical representation based on the values of the model and its residuals.Results. …”
Get full text

Suppression and control of unbalanced and misalignment coupler vibration of a double-rotor permanent magnet drive by Yongcun GUO, Xin MA, Shuang WANG, Deyong LI, Tun YANG

“…In order to effectively suppress vibration, an adaptive factor σ based on the error value and a regularized weight attenuation factor λ are innovatively introduced to quickly respond to system changes and reduce the error. …”
Get full text

Protective Effects of the Ketogenic Diet on Cognitive Impairment Induced by Status Epilepticus in Rats: Modulation of Neuroinflammation Through the NF‐κB Signaling Pathway by Wandi Wang, Lingman Wang, Chunxue Jiang, Shengxuan Zhang, Chen Tan, Liqiong Peng, Ran Ding, Bing Tian, Xiaojie Song, Li Jiang

“…After 7 and 20 days of KD treatment, cognitive function was assessed using the elevated plus‐maze, Morris water maze, novel object recognition, and Y‐maze tests. …”
Get full text

LncRNA PELATON regulates Th2 cell differentiation by miR-10b-5p/GATA3 axis in allergic rhinitis by Zhen Liu, MD, Yumei Li, PhD, Xiangkun Zhao, MM, Qi Sun, MD, Yu Zhang, MD, Yaqi Wang, MM, Han Fang, MD, Yujuan Yang, MD, Yakui Mou, MD, Xicheng Song, MD

Get full text

Succession and Assembly Mechanism of Bacterial Communities in Different Grades of Jinhui Baijiu Daqu during Storage by REN Haiwei, LI Yunfan, ALIMIRE·Keremu, MA Donglin, GUO Xiaopeng, ZHANG Bingyun,ZHANG Zhiliang, LI Yantao, WEI Junqiang

Get full text

A nomogram model based on tumor necrosis factor-like ligand 1A(TL1A) and death receptor-3(DR3) promoter methylation for predicting 90-day prognosis in patients with HBV-associated... by Xue-Fei Wei, Feng Zhang, Han-Xu Zhu, Zhe-Zhe Tian, Miao-Miao Xu, Yu-Chen Fan, Kai Wang, Kai Wang

“…Model performance, including calibration and clinical utility, was evaluated using receiver operating characteristic (ROC) curves, Hosmer-Lemeshow (H-L) tests, and decision curve analysis (DCA). A visual nomogram was constructed to integrate these factors for risk stratification.ResultAnalysis revealed significantly reduced TL1A and DR3 promoter methylation in HBV-ACLF patients, correlating with impaired liver function and coagulation parameters. …”
Get full text

Anticoagulants: dose control methods and inhibitors by V. O. Bitsadze, E. V. Slukhanchuk, J. Kh. Khizroeva, M. V. Tretyakova, V. I. Tsibizova, N. R. Gashimova, I. A. Nakaidze, I. Elalamy, J.-C. Gris, A. D. Makatsariya

“…Age, impaired renal function and concomitant use of antiplatelet agents are common risk factors for bleeding. …”
Get full text

Gender-modulated influence of BDNF concentration and Val66Met polymorphism on cognitive outcomes in chronic limb ischemia patients by Aleksandra Chyrek-Tomaszewska, Alicja Popiołek, Agnieszka Stachowicz-Karpińska, Jacek Budzyński, Katarzyna Linkowska, Mariusz Kozakiewicz, Adam Szelągowski, Alina Borkowska, Maciej Bieliński

“…IntroductionWhile numerous studies have established associations between brain-derived neurotrophic factor (BDNF) and cognitive functioning, limited research has delved into the role of BDNF concerning cognitive outcomes in atherosclerosis-related conditions. …”
Get full text

Reliability and validity of the Transthyretin Amyloidosis – Quality of Life (ATTR-QOL) Questionnaire impact scales by Andrew Lovley, Kristen Hsu, Kaitlin LaGasse, Isabelle Lousada, Kristen L. McCausland, Michelle K. Carty, Sabrina Rebello, Jakob B. Bjorner

“…A scoring algorithm was proposed and tested. Factor structure, differential item functioning, and psychometric properties were explored. …”
Get full text

Excessive External Borrowing in China: Evidence from a Nonparametric Threshold Regression Model with Fixed Effects by Jinjing Tian, Taining Wang, Feng Yao

“…To test our hypotheses, we proposed a nonparametric panel threshold regression model. …”
Get full text