Effects of autolytical fish protein hydrolysate on growth performance, survival rate, and hematological indices in farmed juvenile beluga, Huso huso by Ali Hosseinpour Zelaty

“…The experiment was carried out in 15 tanks (500-L), each containing 50 fish. …”
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Gratitude and sleep disturbance in primary care patients: the mediating roles of health self-efficacy, health behaviors, and psychological distress by Heather R. Altier, Jameson K. Hirsch, Annemarie Weber, Niko Kohls, Jörg Schelling, Loren L. Toussaint, Fuschia M. Sirois, Martin Offenbächer, Martin Offenbächer

“…., recognition and appreciation of experiences, relationships, and surroundings), a positive psychological cognitive-emotional characteristic, may serve as a catalyst of these beneficial downstream effects, given its association with improved health functioning and sleep.MethodsIn a sample of primary care patients (N = 869, M age = 53; 60.7% female) from 50 urban and 30 rural practices in Germany, health self-efficacy (i.e., belief in ability to perform necessary actions to manage health) and constructive health behaviors (i.e., actions taken to modify health positively), separately and together as parallel first-order mediators, and stress, anxiety, and depression, as parallel second-order mediators, were investigated as potential serial mediators of the association between gratitude and sleep disturbances. …”
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OTUD1 exacerbates sepsis-associated encephalopathy by promoting HK2 mitochondrial release to drive microglia pyroptosis by Guoqing Jing, Hailong Gong, Han Wang, Jing Zuo, Die Wu, Huifan Liu, Xing Wang, Min Yuan, Yun Xia, Tongtong Du, Wanhong Liu, Xiaojing Wu, Xuemin Song

“…Our findings address a key knowledge gap by elucidating the OTUD1-HK2 axis as a novel regulatory pathway in SAE, offering potential therapeutic targets to mitigate cognitive deficits in sepsis. Methods Single-cell RNA sequencing was used to identify SAE-specific microglia subpopulations and analyze the expression of deubiquitinases within these subpopulations. …”
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Teachers' Perceptions of the Implementation of the Merdeka Curriculum at SMA Muhammadiyah 5 Yogyakarta by Ica Lalitya Kusuma, Enung Hasanah, Sukirman Sukirman

“…It aims to identify challenges and conveniences faced by teachers during its application, focusing on how the curriculum's core principles align with modern educational needs. Design/methods/approach – A qualitative descriptive approach was used, collecting data through semi-structured questionnaires completed by 21 teachers from various disciplines. …”
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NAP1L5 in acute myeloid leukemia: a prognostic biomarker and potential therapeutic target by Meng Wang, Meng Wang, Zhibin Xie, Yuanyuan Tan, Yan Zhou, Tingting Zhang, Yuqing Du, Huan Wu, Lili Zhou, Jian Ge

“…However, its specific role and molecular mechanisms in acute myeloid leukemia (AML) remain largely unexplored.MethodsTo identify key genes associated with AML, we analyzed gene expression profiles from AML patients and healthy controls using microarray datasets obtained from the GEO database. …”
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Virtual Reality Portable Perimetry and Home Monitoring of Glaucoma: Retention and Compliance over a 2-year Period by Runjie B. Shi, MD, PhD, Leo Y. Li-Han, PhD, Irfan N. Kherani, MD, FRCSC, Graham E. Trope, PhD, FRCSC, Yvonne M. Buys, MD, FRCSC, Willy Wong, PhD, Moshe Eizenman, PhD

“…Subjects: Twenty-five glaucoma patients with stable and reliable VFs (average age 67.4 years) were recruited at Toronto Western Hospital, Ontario, Canada. Methods: Participants were instructed to perform bilateral home VF tests fortnightly for 2 years using the Toronto Portable Perimeter (TPP). …”
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Ecological Momentary Assessment of Mental Health Problems Among University Students: Data Quality Evaluation Study by Ana Portillo-Van Diest, Philippe Mortier, Laura Ballester, Franco Amigo, Paula Carrasco, Raquel Falcó, Margalida Gili, Glenn Kiekens, Francisco H Machancoses, Jose A Piqueras, Marisa Rebagliato, Miquel Roca, Tíscar Rodríguez-Jiménez, Jordi Alonso, Gemma Vilagut

“…MethodsA total of 1259 university students were invited to participate in a 15-day EMA study on mental health problems. …”
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Antibacterial Efficacy and Antioxidant Potential of Hafnium-coated Titanium Implants: An In-vitro Assessment by Vishaka Kothari, Vaishnavi Rajaraman, Padma Ariga, Saravanan Sekaran, Dhanraj M Ganapathy

“…Aim: This study evaluated the antibacterial efficacy and antioxidant potential of hafnium-coated titanium implants through in-vitro experiments. Materials and Methods: The present in-vitro study was conducted at the Saveetha Dental College and Hospitals, Chennai, India, over a duration of three months (March to May 2024) in an in-vitro experimental set-up. …”
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Metabolism-associated marker gene-based predictive model for prognosis, targeted therapy, and immune landscape in ovarian cancer: an integrative analysis of single-cell and bulk RN... by Lele Ling, Bingrong Li, Boliang Ke, Yinjie Hu, Kaiyong Zhang, Siwen Li, Te Liu, Peng Liu, Bimeng Zhang

“…Thus, it is of utmost significance to identify potent prognostic biomarkers and delve into the exploration of novel therapeutic drugs and targets, in pursuit of advancing the treatment of OC. Methods Single-cell RNA sequencing (scRNA-seq) data related to OC were analyzed using AUCell scores to identify subpopulations at the single-cell level. …”
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Comparison of the Performance Between the Montbiliard × Holstein Crossbred and Holstein Calves in Hot and Humid Areas by Pirouz Shakeri, Hassan Khamisabadi, Mehdi Bahrami Yekdangi, Mahdi Abasy Firouzjaei, Amir Ali Shakeri

“…This study aimed to compare feedlot performance between the male Montbiliard × Holstein (M × H) crossbred and purebred Holstein (H) calves over 6 months in hot and humid conditions of Iran. Methods: The experiment was carried out at the national research and development cattle station of Gawdasht in the suburbs of Babol, Mazandaran Province. …”
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Effect of Wuzhuyu Decoction on alcoholic gastric ulcer and its mechanism by GAO Ruiyang, LI Jingyao, LI Pingxiang, GE Keli

“…Objective To investigate the effect of Wuzhuyu Decoction (WZYD) on alcoholic gastric ulcer and its mechanism. Methods A total of 120 female KM mice, aged 8 weeks, were randomly divided into normal control group (group A), model control group (group B), ranitidine group (group C), and low-, middle-, and high-dose WZYD groups (groups D-F), with 20 mice in each group. …”
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Response of yield and yield components of six genotypes of Pinto beans (Phaseolus vulgaris L.) inoculation with Rhizobium phaseoli Khavari *, H. & Shakarami2, Gh. by Hadi khavari, Ghodratolah Shakarami

“…On the other hand, unbalanced consumption without management of chemical inputs has led to instability in agricultural ecosystems and the irreparable economic and environmental consequences of their consumption in agriculture are known throughout the world.   Materials & Methods An experiment was conducted as factorial based on a randomized complete block design with three replications during growing season of 2017 at the experimental field of Beiranshahr city of Khorramabad in Lorestan Province, Iran (42° 79' E, 36° 70' N and 1669m above the sea level). …”
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Deciphering the tumor immune microenvironment: single-cell and spatial transcriptomic insights into cervical cancer fibroblasts by Zhiheng Lin, Youwei Zhou, Zhenran Liu, Wenyang Nie, Hengjie Cao, Shengnan Li, Xuanling Li, Lijun Zhu, Guangyao Lin, Yanyu Ding, Yi Jiang, Zuxi Gu, Lianwei Xu, Zhijie Zhao, Huabao Cai

“…By constructing a prognostic model and exploring the immune microenvironment, we aim to provide novel insights into CC pathogenesis and potential therapeutic strategies. Methods We utilized scRNA-seq, spatial transcriptomics, deconvolution analysis, and pseudotime trajectory mapping to delineate fibroblast subtypes within the tumor immune microenvironment (TIME) of CC. …”
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Proteomic signatures and predictive modeling of cadmium-associated anxiety in middle-aged and elderly populations: an environmental exposure association study by Sheng Wan, Yong Yang, Qihan Zhao, Zelong Xing, Jie Li, Hao Gao, Yinghui Yin, Zhenzhong Liu, Qiwen Chen, Maoqin Tian, Xinxin Shi, Ziyue Ji, Shaoxin Huang

“…Plasma proteomic profiling was performed using data-independent acquisition (DIA) quantitative technology with an LC–MS/MS platform (timsTOF Pro, Bruker Daltonics), systematically characterizing 2,531 proteins across all samples. Machine learning techniques, specifically XGBoost and LASSO, were employed to identify biomarkers that were subsequently validated through mediation analysis and animal experiments, allowing for the screening of key protein signatures. …”
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Differential expression of plasma extracellular vesicles microRNAs and exploration of their association with bone metabolism in childhood trauma participants treated in a psychosom... by Yangyang He, Yangyang He, Karin Wuertz-Kozak, Karin Wuertz-Kozak, Petra Cazzanelli, Sanne Houtenbos, Sanne Houtenbos, Francisco Garcia-Carrizo, Francisco Garcia-Carrizo, Tim J. Schulz, Tim J. Schulz, Tim J. Schulz, Pia-Maria Wippert, Pia-Maria Wippert

“…MiRNA target gene network prediction revealed highly associated target genes of dysregulated miRNAs, such as Trinucleotide Repeat Containing Adaptor 6B (TNRC6B), and enrichment analysis highlighted pathways including the forkhead box protein O (FoxO) signaling pathway.DiscussionsThis study explored the potential associations between childhood trauma and bone metabolism, due to the sample size and experimental group limitations, these associations should be validated in future experiments with larger sample sizes and different control group settings.…”
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Effects of nitrogen application time on fruit setting rate and lignin accumulation during sepal development of Kuerlexiangli pear by GUO Kailu, WANG Lanfei, YU Mingyang, FAN Weifan, BAO Jianping

“…The collected samples were used for the determination of the lignin content and related enzyme activities. …”
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Evaluation of the Prebiotic Effect of Spirulina platensis Algal Extract on Lactobacillus acidophilus Survival and Physicochemical Properties of Feta Cheese by Ahmad Yazdani, Hamidreza Kazemeini, Ahmad Nazaktabar

“…Therefore, this study aimed to investigate the prebiotic effect of Spirulina platensis algal extract on Lactobacillus acidophilus bacteria survival and the physical, chemical, and sensory properties of feta cheese during storage at 4 °C for49 days. Methods: S. platensis extract was purchased, ground, and shaken for 48 h. …”
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Effect of arbuscular mycorrhizal fungi on the relationship between root respiration and ultraweak luminescence under salt stress in strawberry by LI Jiafeng, WANG Zhenfan, YANG Bo, FAN Li

“…The objectives of this study were to investigate the changes in root respiration, enzyme activities, and UWL intensity after AMF inoculation on the roots of strawberry under salt stress, and to assess the possibility of UWL as a potential indicator of plant physiological status under salt stress. [Methods] The strawberry cultivar Benihoppe was selected for the experiments. …”
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MiR‐223‐3p affects the proliferation and apoptosis of HCAECs in Kawasaki disease by regulating the expression of FOXP3 by Ronghao Zheng, Jing Xie, Weijie Li, Jianping Shang, Zuliang Shi, Songbai Zhu, Lin Gui, Li Huang, Lan Shu, Donglei Liu, Yi Gong, Xiaohui Li, Wanxia Chai, Xiaofen Huang, Xiaolin Wu, Jing Yue

“…Methods Blood samples were collected in acute febrile phase of KD, after IVIG treatment, and from healthy controls. …”
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Neurotropic Effects of Cortexin on Models of Mental and Physical Developmental Delay by Denis V. Kurkin, Dmitry A. Bakulin, Evgeny I. Morkovin, Vladimir I. Petrov, Andrei V. Strygin, Alexey V. Smirnov, Maksim V. Shmidt, Julia V. Gorbunova, Yury A. Kolosov, Olga V. Ivanova, Ivan S. Krysanov, Marina A. Dzhavakhyan, Andrew V. Zaborovsky, Valeria B. Saparova, Igor E. Makarenko, Roman I. Drai, Ilia A. Lugovik, Nikolay A. Verlov, Vladimir S. Burdakov

“…In a separate series of experiments in mice, the concentration of the test drug cortexin and the reference drug cerebrolysin was determined in blood and brain tissue samples using radioactive iodine (Na125I) labeling of these preparations. …”
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