Nursing Students' Perspectives on Integrating Artificial Intelligence Into Clinical Practice and Training: A Qualitative Descriptive Study by Moustaq Karim Khan Rony, Sumon Ahmad, Dipak Chandra Das, Sabren Mukta Tanha, Tuli Rani Deb, Mosammat Ruma Akter, Mst. Amena Khatun, Md Ibrahim Khalil, Umme Rabeya Peu, Mst. Rina Parvin, Daifallah M. Alrazeeni, Fazila Akter

“…Aim This study aimed to explore nursing students' perceptions of incorporating AI into their clinical training and professional practice, with a focus on identifying benefits, challenges, and potential areas for improvement. Methods A qualitative descriptive design explored the experiences and attitudes of 25 nursing students from five colleges in Dhaka, Bangladesh. …”
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Assessment of NUDT5 in Endometrial Carcinoma: Functional Insights, Prognostic and Therapeutic Implications by Hongfei Yu, Lingling Zu, Yuqin Zang, Fei Teng, Tao Wang, Ming Wu, Yingmei Wang, Fengxia Xue

“…This study aims to investigate the role of <i>nucleoside diphosphate-linked moiety X motif 5 (NUDT5)</i> in EC and evaluate its potential as a biomarker and therapeutic target. <b>Methods</b>: This study analyzed gene expression data from The Cancer Genome Atlas and performed tissue microarray validation to assess <i>NUDT5</i> expression in EC samples. …”
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GG-NER’s role in androgen receptor signaling inhibitor response for advanced prostate cancer by Chuanfan Zhong, Jiaxing Wang, Hangyang Peng, Jianming Lu, Zining Long, Zhuoyuan Lin, Guo Chen, Chao Cai, Shilong Cheng, Zhongjie Chen, Le Zhang, Weibo Zhong, Rujun Mo, Xiangming Mao

“…Addressing the clinical challenge of identifying non-responsive patients and discovering new therapeutic targets is urgently needed. Methods We utilized single-sample gene set enrichment analysis (ssGSEA) to elucidate the influence of the GG-NER pathway on ARSI response in PCa. …”
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Moderate-to-vigorous group aerobic exercise versus group leisure activities for mild-to-moderate depression in adolescents: study protocol for a multicentre randomised controlled t... by Carl Johan Sundberg, Andreas Ivarsson, Ingrid Larsson, Eva Serlachius, Maria Lalouni, Fabian Lenhard, Håkan Jarbin, Rebecca Mortazavi, Jessica Norrbom, Emma Haglund, Tina Cronqvist, Kristina Ingemarsson, Åsa Mårsell, Olof Rask, Rebecca Andersson

“…Secondary outcomes are self-rated Quick Inventory of Depressive Symptomatology, self-rated functioning; clinician-rated improvement and functioning; objectively measured aerobic capacity, muscular strength, muscular endurance, body composition and presence or activity of selected biological markers of neuroprotection and neuroinflammation in blood samples. Further outcomes are cost-effectiveness and adolescents’, parents’ and coaches’ experiences of the interventions and an exploration of how the adolescents’ health and lifestyle are influenced by the interventions through qualitative interviews.Ethics and dissemination The study is approved by the Swedish Ethical Review Authority (Ref. 2021-05307-01). …”
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Stakeholder perspectives on digital wellbeing in Saudi Arabia: a cross-sectional survey by Saud Abdulaziz Alomairah, Michelle Colder Carras, Dahlia Aljuboori, Juliann Saquib, Nazmus Saquib, Mayank Date, Kyeongwon Kim, Faisal Aldayel, Michelle R. Kaufman, Laura K. Clary, Vincent G. van der Rijst, Anouk Tuijnman, Antonius J. van Rooij, Nahlah Alsogaih, Faisal Z. Al-Zabidi, Fahad S. Albeyahi, Johannes Thrul

“…Objective This study aimed to gather insights from societal stakeholders, including youth, parents, policymakers, industry leaders, clinicians, educators, and digital media users, to inform culturally tailored interventions for digital well-being in Saudi Arabia. Methods A purposeful non-random sample of 92 participants representing different stakeholder groups was recruited to complete an online survey, answering questions about their experiences and perspectives on digital media use. …”
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IGF2BP3 Modulates mRNA Splicing and Stability to Promote Trophoblast Progression via Interaction with PDE3A and Suppression by miR-196a-5p in Preeclampsia by Chunyan Li, Pingpo Ming, Cuifang Fan, Jiao Chen, Jing Yang

“…However, the exact mechanisms of AS in PE remain poorly understood. <b>Methods:</b> To elucidate AS-mediated regulatory pathways in PE, a total of 38 fresh-frozen placental samples, including 13 pre-eclampsia samples and 25 normal control samples, were collected from Renmin Hospital of Wuhan University between 1 February and 30 July 2022. …”
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Targeting PRMT1-mediated methylation of TAF15 to protect against myocardial infarction by inhibiting ferroptosis via the GPX4/NRF2 pathway by Guanshen Huang, Liwei He, Bishan Liang, Mingjian Gao, Jianming Huang, Hao Xia, Xinyu Li, Hai Li, Yunjun Ruan

“…This study aims to investigate the role and potential regulatory mechanism of TAF15 in AMI. Methods Bioinformatics analysis of gene expression datasets was conducted to identify differentially expressed genes in AMI samples. …”
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Incorporating social determinants of health into agent-based models of HIV transmission: methodological challenges and future directions by Anna L. Hotton, Pedro Nascimento de Lima, Arindam Fadikar, Nicholson T. Collier, Aditya S. Khanna, Darnell N. Motley, Eric Tatara, Sara Rimer, Ellen Almirol, Harold A. Pollack, John A. Schneider, John A. Schneider, John A. Schneider, Robert J. Lempert, Robert J. Lempert, Jonathan Ozik

“…However, such interventions are resource-intensive and logistically challenging, and their evaluation is often limited by small sample sizes and short duration of follow-up. Because they allow for both detailed and large-scale simulations of counterfactual experiments, agent-based models (ABMs) can demonstrate the potential impact of combinations of interventions that may otherwise be infeasible to evaluate in empirical settings and help plan for efficient use of public health resources. …”
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Xylem Sap Mycobiota in Grapevine Naturally Infected with <i>Xylella fastidiosa</i>: A Case Study: Interaction of <i>Xylella fastidiosa</i> with <i>Sclerotinia sclerotiorum</i> by Analía Perelló, Antonia Romero-Munar, Sergio I. Martinez, Antonio Busquets, María Cañellas, Bárbara M. Quetglas, Rafael Bosch, Jaume Vadell, Catalina Cabot, Marga Gomila

“…The xylem sap was collected from Cabernet Sauvignon vines in Mallorca, Spain, and fungal communities were characterized using culture-dependent methods. Both beneficial fungi (e.g., <i>Aureobasidium pullulans</i>, <i>Rhodotorula mucilaginosa</i>) and pathogenic species (e.g., <i>S. sclerotiorum</i>, <i>Cladosporium</i> sp., <i>Alternaria alternata</i>, and the <i>Phoma</i> complex) were isolated from both <i>Xff</i>-positive and <i>Xff</i>-negative plants, indicating similar community profiles. …”
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Two decades of Lloviu virus in Europe: knowns and unknowns about the European filovirus by Dr Gábor Kemenesi, Dr Zsófia Lanszki, Ágota Ábrahám, Dr Sándor A Boldogh, Dr Simon Scott, professor Nigel Temperton, Dr Edward Wright, Dr Pierre Nouvellet, Dr Stefania Leopardi, Dr Paola Di Benedictis, Dr Adam Hume, Dr Elke Mühlberger, Levente Sipos-Szabó, Dr Dávid Bajusz, Dr Heliana Dundarova, Dr Szilárd L Bücs, Dr Branka Bajić, Dr Ivana Budinski, Dr Štefan Matis, Dr Tamás Görföl

“…Using a mobile laboratory approach, we collected fresh blood samples from infected animals on-site to facilitate in vitro isolation experiments. …”
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Concurrent training and intermittent fasting reduce transverse cross-sectional area of cardiomyocytes and body mass in Wistar rats by Henrique Izaias Marcelo, Henrique Izaias Marcelo, Marina Politi Okoshi, Letícia Estevam Engel, Wanderson da Silva Rosa, Paulo Henrique Aleixo, Paulo Henrique Aleixo, Guilherme Akio Tamura Ozaki, Everton Alex Carvalho Zanuto, Luiz Carlos Marques Vanderlei, Francis Lopes Pacagnelli, Francis Lopes Pacagnelli, Robson Chacon Castoldi

“…The intermittent fasting period was 12/12 h. At the end of the experiment, the animals were weighed to obtain the Lee index; heart weight was verified, and tissue samples were collected for further histological analysis. …”
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Positive selection on rare variants of IGF1R and BRD4 underlying the cold adaptation of wild boar by Jianhai Chen, Ivan Jakovlić, Mikhail Sablin, Shengqian Xia, Zhixiang Xu, Yapin Guo, Renzuo Kuang, Jie Zhong, Yangying Jia, Nhien Thuy Thi Tran, Hao Yang, Hong Ma, Nikica Šprem, Jianlin Han, Di Liu, Yunxia Zhao, Shuhong Zhao

“…Methods We conducted whole-genome resequencing on wild populations from cold regions (northern and northeastern Asia, with six samples) and warm regions (southeastern Asia and southern China, with five samples). …”
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Identification of stable reference genes and differential miRNA expression in Sri Lankan type 2 diabetes mellitus patients: a cross-sectional study by Palihaderu Arachchige Dineth Supasan Palihaderu, Balapuwaduge Isuru Layan Madusanka Mendis, Jayasekara Mudiyanselage Krishanthi Jayarukshi Kumari Premarathne, Wajjakkara Kankanamlage Ruwin Dias, Swee Keong Yeap, Wan Yong Ho, Arosha Sampath Dissanayake, Iyanthimala Harshini Rajapakse, Panduka Karunanayake, Upul Senarath, Dilan Amila Satharasinghe

“…This study aimed to identify reference microRNA s in type 2 Diabetes mellitus plasma and validate two target microRNAs among a Sri Lankan population with type 2 diabetes mellitus.MethodsThis is a cross-sectional experiment. A total of fifty-three (N = 53) non-hemolyzed plasma samples from individuals with type 2 diabetes mellitus were selected to evaluate stability, in comparison to thirty-eight (N = 38) normoglycemic non-hemolyzed plasma samples. …”
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Callogenesis and regeneration of common bean (Phaseolus vulgaris L.) by using thin cell layer explants by Atefeh Bakhshian, Khadijeh Bagheri

“…Still, there is not an optimized protocol for beans regeneration and this is a big challenge for bean breeding through genetic engineering   Material & Methods In this study, two experiments were conducted to evaluate callus induction and regeneration in bean. …”
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Nitrogen fertilization enhances soil quality in the short-term in irrigated intensified maize systems by Victoria Lafuente, Ana Bielsa, María Alonso-Ayuso, Samuel Franco-Luesma, Carmen Castañeda, Laura B. Martínez-García, José L. Arrúe, Jorge Álvaro-Fuentes

“…Area of study: Zaragoza province, Spain Material and methods: The field experiment involved a strip plot design with three growing systems – maize monoculture (MM), pea-maize (PM), and barley-maize (BM)– and three fertilisation levels: unfertilised (0N), medium nitrogen (MN), and high nitrogen (HN). …”
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Dynamics of oxylipin biosynthesis in systemic inflammation: insights from a large animal model of endotoxemia by Madison N. Myers, Miguel Chirivi, Jose M. dos Santos Neto, Jair Parales-Girón, Lynn C. Worden, Adam L. Lock, G. Andres Contreras

“…However, the dynamics of OXL production during systemic inflammation remain poorly defined, particularly in large animals.MethodsTo investigate OXL responses to endotoxemia, mature Holstein cows were administered intravenous infusions of either LPS or sterile saline (SAL). …”
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Minority stress and stimulant use among US adult sexual minority men: A systematic review by Michael Miller-Perusse, Keith J. Horvath, Jessica L. Montoya, David J. Moore, Adam W. Carrico, Vanessa B. Serrano

“…Methods: PubMed, PsycInfo, CINAHL, and Scopus searches between November 2022 and October 2023 identified 991 studies, with 13 meeting selection criteria: English, peer-reviewed publication reporting an estimated minority stressor–stimulant use association among US adult SMM. …”
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Human saliva exerts strong type-dependent effects on adenovirus infectivity by Erwan Sallard, Wenli Zhang, Nikita Chilakamarri, Setareh Farzanehkari, Setareh Farzanehkari, Inga Marte Charlott Seuthe, Anja Ehrhardt, Malik Aydin, Malik Aydin

“…All human Ads used were replication-competent and expressed a GLN cassette containing a green-fluorescent protein, nano-luciferase, and neomycin resistance. Loss-of-function experiments were conducted by immunoprecipitation or enzymatic digestion of specific saliva components to decipher related mechanisms.ResultsTemporal and inter-individual variability in saliva samples were observed, validating the use of a saliva pool to represent the population. …”
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Socio-demographic factors related to children’s knowledge about their rights to healthcare services in transitional Albania by Herion Muja, Herion Muja, Herion Muja, Suela Vasil, Suela Vasil, Andis Qendro, Timo Clemens, Dorina Toçi, Dorina Toçi, Ervin Toçi, Helmut Brand, Genc Burazeri, Genc Burazeri

“…BackgroundOur aim was to assess the level and socio-demographic correlates of knowledge about rights to healthcare services among children in post-communist Albania in order to inform targeted interventions and policies to promote equitable healthcare access for all children.MethodsAn online survey conducted in Albania in September 2022 included a nationwide representative sample of 7,831 schoolchildren (≈54% girls) aged 12–15 years. …”
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Highly proliferating cancer cells function as novel prognostic biomarkers for lung adenocarcinoma with particular usefulness for stage IA risk stratification by Yanlu Xiong, Yongfu Ma, Jie Lei, Jianfei Zhu, Nianlin Xie, Feng Tian, Qiang Lu, Miaomiao Wen, Qian Zheng, Yong Han, Tao Jiang, Yang Liu

“…We aimed to molecularly stratify LUAD patients especially for stage IA. Methods We analysed tumour heterogeneity and identified highly proliferating cancer cells (HPCs) in LUAD by performing single-cell RNA sequencing (scRNA-seq) analysis, immunohistochemical (IHC) staining using a tissue microarray, flow cytometry and biological experiments. …”
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