Overexpression of oncogenic polo-like kinase 1 disrupts the invasiveness, cell cycle, and apoptosis in synovial sarcoma by Jun Zhang, Zhong Li, Ming-Yu Xie, Ning Wang, Hao Liu, Feng Li, Li-Juan Pang, Yan Qi

“…Therefore, PLK1 could act as a promising target for treating various cancers, including a low incidence of sarcoma. Methods SS paraffin-embedded tissue samples were selected to detect the expression of PLK1 and apoptosis- and autophagy-related proteins using immunohistochemistry. …”
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Lightweight detection algorithms for small targets on unmanned mining trucks by Shuoqi CHENG, Yilihamu·YAERMAIMAITI, Lirong XIE, Xiyu LI, Ying MA

“…With the continuous development of artificial intelligence technology and the gradual advancement of the smart mining concept, traditional open-pit mining operations are being replaced by automated methods. Unmanned mining trucks are a crucial component of smart mining. …”
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Healthcare-seeking behaviors and barriers among medical students in Egypt: a national cross-sectional study by Ghada O. El-Khawaga, Yusof M. Omar, Mohamed Elsaadany, Mohamed Ghazy, Amr Khaled Abdelaal, Mahmoud Hekal, Abdel-Hady El-Gilany, H. S. B. team of collaborators

“…This study aims to examine the healthcare-seeking behaviors and barriers among medical students in Egypt. Methods This cross-sectional study involved a convenience sample of 1,535 medical students from 12 public universities across Egypt. …”
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Research on High-Accuracy, Lightweight, Superfast Model for Nitrogen Diagnosis and Plant Growth in Lettuce (<i>Lactuca sativa</i> L.) by Xuyang Li, Iftikhar Hussain Shah, Xiaohao Gong, Muhammad Azam, Wu Jinhui, Pengli Li, Yidong Zhang, Qingliang Niu, Liying Chang

“…A machine learning approach was also applied to data collected from RGB and hyperspectral imaging systems. Traditional methods for nitrogen diagnosis in lettuce, such as laboratory-based analysis of plant samples, are labor-intensive, time-consuming, and lack real-time monitoring capabilities. …”
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Protective Effect of Lithium Chloride on EndotheliaL Cells in Septic Shock by O. A. Grebenchikov, V. T. Dolgikh, M. D. Prokofiev, I. S. Kasatkina, A. V. Ershov

“…The aim is to study the effectiveness of lithium chloride for preventing damage to the monolayer of endothelial cells in vitro exposed to serum of patients with septic shock.Material and methods. Serum samples prepared from blood of 5 septic shock patients selected according to «Sepsis-3» criteria and 5 healthy volunteers (control serum) were used in the study. …”
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Hepatoprotective Effect of Silymarin Peptide on Carbon Tetrachloride-Induced Acute Liver Injury in Mice by Ananda, Tsend-Ayush Damba, Xiulan Su, Khurelbaatar Nyamdavaa

“…The treatment of silymarin was used as a positive control. At the end of the experiments, mice were euthanized, and the blood and liver samples were collected. …”
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Strategies to foster stakeholder engagement in residency coaching: a CFIR-Informed qualitative study across diverse stakeholder groups by Marzena Sasnal, Rachel M. Jensen, Uyen T. Mai, Carl A. Gold, Aussama K. Nassar, James R. Korndorffer, Arden M. Morris, Rebecca K. Miller-Kuhlmann

“…The purpose of this article is to identify strategies to foster engagement of diverse stakeholder groups in coaching interventions.Material and Methods We conducted 35 semi-structured interviews between November 2021 and April 2022 with purposively sampled key stakeholders that captured participants’ perspectives on physicians’ communication training needs, roles, and involvement in, as well as contextual factors, facilitators, barriers, and improvement strategies of the multi-departmental Communication Coaching Program at our institution. …”
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The Influence of the Clinical Context on nursing organizational well-being: A Cross-sectional study by Valerio Della Bella, Jacopo Fiorini, Francesco Zaghini, Alessandro Sili

“…This study aims to identify which variables in specific nursing clinical contexts are associated with their reported organizational well-being. Methods. A descriptive cross-sectional study was conducted using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist. …”
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Bone marrow mesenchymal stem cells overexpressing stromal cell- derived factor 1 aid in bone formation in osteoporotic mice by Yanghao Wang, Ya Xiao, XinYu Yang, Fei He, Jun Hu, Guang Yang, Weizhou Wang

“…We aimed to investigate if the increased SDF1 concentration facilitated cell migration to the bone. Methods We used lentivirus to construct BMSCs overexpressing SDF1 or knocking down CXCR4. …”
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Effects of valproate on the entry of inert hydrophilic markers and expression of tight junction associated genes in the neonatal brain and choroid plexus of a rat model of epilepsy... by Fiona Qiu, Katarzyna M. Dziegielewska, Mark D. Habgood, Yifan Huang, Norman R. Saunders

“…After 5 min, plasma, CSF and brain samples were collected for radioactivity measurement. …”
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Dynamics of alterations in white blood cell and sepsis-associated humoral factors during sulfur mustard intoxication by S. P. Sidorov, A. A. Sergeev, E. B. Zhakovko, S. V. Chepur, A. A. Kuzmin, T. V. Shefer, A. S. Alekseeva

“…The aim is to assess the features of immune response and intestinal bacterial translocation during SM intoxication. Materials and methods. The experiments were performed with Chinchilla male rabbits. …”
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Causal relationships between alterations in shear stress-related genes and aneurysmal subarachnoid hemorrhage by Xiaoxin Wu, Yuanyuan Dai, Xingyang Niu, Minghao Zhang, Jiaoxing Li, Yi Xie, Wenli Sheng, Fei Ye

“…This study aimed to elucidate the causal association of key SS-related genes with aSAH. Methods SS-related genes were curated from the GeneCards database and transcriptomic datasets responsive to SS conditions. …”
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Uncovering the Interplay of Ferroptosis and Immune System in Coronary Artery Disease: Construction and Validation of a Diagnostic Model by Zhang Z, Zhu X, Zhang T, Li C, Zhang D, Li W, Zhao L

“…In vitro and in vivo experiments included qPCR, ELISA, pathological examination, and Western blot.Results: In the GSE202625 dataset, 70 genes were upregulated and 895 genes were downregulated in CAD samples. …”
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Exploiting Chestnut Biochar as a Functional and Circular Ingredient in Weaned Piglet Diets by Luciana Rossi, Sara Frazzini, Matteo Santoru, Benedetta Canala, Irene Ferri, Alessandra Moscatelli, Elisabetta Onelli, Matteo Dell’Anno, Salvatore Pilu, Serena Reggi

“…This study therefore evaluates the effects of biochar supplementation on growth performance and health parameters in weaned piglets. Methods: A total of 223 piglets were divided into two experimental groups: the control (CTRL) group and the treatment (TRT group). …”
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GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2 by Qingyi Hu, Qianzhi Chen, Wen Yang, Anwen Ren, Jie Tan, Tao Huang

“…Investigating the mechanism underlying TNBC’s resistance to platinum-based chemotherapy and identifying new therapeutic targets are urgent priorities. Methods The expression level of GPX3, cisplatin sensitivity, and ROS production were compared across three TNBC cell lines to elucidate the relationship between GPX3 and platinum resistance. …”
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Patients’ trajectory from tooth loss to dental rehabilitation and living with implant-supported dentures – a qualitative interview study by Gabriele Müller-Mundt, Philipp-Cornelius Pott, Lara Prinz, Simone Schaumann, Meike Stiesch, Nils Schneider, Franziska A. Herbst

“…Methods The single-site study employed an exploratory, qualitative design with semi-structured interviews conducted with patients who had received implant-supported dentures for different indications at least one year prior. …”
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Protective effect of Korean red ginseng water extract on levothyroxine-induced hyperthyroidism and propylthiouracil-induced hypothyroidism in rats by Lei Huang, Won Young Jang, Ji Hye Yoon, Zhenyan Piao, Jinghan Su, Dong Seon Kim, Ki Woong Kwon, Ji Won Kim, Sang Hee Park, Sunggyu Kim, Jong-Hoon Kim, Jae Youl Cho

“…At the experiment's conclusion, rats were sacrificed, and blood, thyroid gland, and liver samples were collected. …”
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Understanding how older people with mild frailty engage with behaviour change to support their independence: a qualitative study by Benjamin Gardner, Louise Marston, Kate R Walters, Vari M Drennan, Rachael Frost, Paul Chadwick, Rebecca L Gould, Yolanda Barrado-Martin, Sarah Gibson, Rekha Elaswarapu, Rashmi Kumar, Kalpa Kharicha, Tasmin Alanna Rookes, Christina Avgerinou, Jane Hopkins, Jessica Catchpole, Claire Jowett

“…Interviews explored participation experiences, including engagement, perceived progress and impact. …”
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Patients’, caregivers and clinicians’ perspectives on education and support about methotrexate: survey to 26 European Countries by Cristiano Matos, Polly Livermore, Mariana Ortiz-Piña, Khadija El Aoufy, Kristina Buerki, Agnes Ágoston-Szabó, Darja Batšinskaja, Jana Melicharová, Marie-Louise Karlsson, Karlien Claes, Ana Isabel Rodriguez Vargas, Ellen Moholt, Ane Ludvigsen, Una Martin, Ulrike Erstling, Angela Camon, Ana Pais, Mikaella Konstantinou, Myrto Nikoloudaki, Souzi Makri, Bruno Silva, Cláudia Paiva, Elena Nikiphorou, Andrea Marques, Ricardo J. O. Ferreira

“…Methods: An international team of researchers and clinicians, including rheumatology nurses, a pharmacist, a rheumatologist, and three patient representatives, developed a survey. …”
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Calibration of Short-Wave Infrared Spectrometer for Atmosphere Methane Monitoring by Haoran Li, Fuqi Si, Liang Xi, Fang Lin, Yu Jiang, Fenglei Liu, Yi Zeng, Yunkun Han, Kaili Wu

“…Concurrently, a methane sample gas experiment was performed using the integrating-sphere light source, and the measurement error was less than 4%. …”
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