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9821
Emotional pictures in the brain and their interaction with the task: A fine-grained fMRI coordinate-based meta-analysis study
Published 2025-01-01“…The impacting research on emotions of the last decades was carried out with different methods. The most popular was based on the use of a validated sample of slides, the International Affective Pictures System (IAPS), divided mainly into pleasant, neutral and unpleasant categories, and on fMRI as a measure of brain activation induced by these stimuli. …”
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9822
An Analysis on Tendency Components on Strategic Approach in the Process of Urban Planning in Iran
Published 2016-06-01“…Besides the statistical models are used to analyze the data obtained from single-sample T (One T sample test) and linear regression analysis (Linear. …”
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9823
Analysis of the temperature factor’s influence on the pharmacotechnological parameters of the experimental cream «myco-protection plus active» for local therapy of foot mycoses (in...
Published 2025-06-01“…For example, at the fifth minute of the experiment, a mass change of 1.31 mg (3.62%) was observed at 61.22°C. …”
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9824
Selective blockade of acid-sensing ion channel 1a can provide substantial hippocampal neuroprotection
Published 2025-07-01“…In addition, further research is required to determine whether selective ASIC1a blockade is a viable therapeutic strategy for TLE.MethodsThe localization and expression levels of ASIC1 and mRNA levels of ASIC1a were detected when the Rho/ROCK and PI3K signaling pathways were activated and inhibited in glutamate (Glu)-induced cell. …”
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9825
Preparation and characterization of biomineralizing dentin bonding primer based on bioactive amphiphilic raspberry-like nanoparticles
Published 2025-08-01“…This study developed a biomineralizing dentin bonding primer incorporating bioactive amphiphilic raspberry-like nanoparticles (BRPs) to enhance biomineralization and dentin bond strength. Methods BRPs were characterized using scanning electron microscopy (SEM) and nitrogen (N2) adsorption experiments. …”
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9826
Integrated bioinformatics analysis of the crucial candidate genes and pathways associated with glucocorticoid resistance in acute lymphoblastic leukemia
Published 2020-04-01“…In this study, we used bioinformatic analysis methods to integrate the candidate genes and pathways participating in GC resistance in ALL and subsequently verified the bioinformatics findings with in vitro cell experiments. …”
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9827
Highly efficient batch adsorption of anionic dye in wastewater using nanocomposite: Experimental and theoretical studies
Published 2024-01-01“…The adsorptive properties of the Erionyl Red (ER) dye on bentonite (B) intercalated with cetyltrimethylammonium bromide (HDTMA-B) were investigated using experimental and statistical physics methods. The dye was then taken up by the intercalated bentonite from a real water sample. …”
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9828
Characterization of Nodulation-Compatible Strains of Native Soil Rhizobia from the Rhizosphere of Soya Bean (<i>Glycine max</i> L.) Fields in South Africa
Published 2024-12-01“…A glasshouse soil trap experiment using soil samples collected from Lothair, Bothaville, and Standerton was performed on five cultivars. …”
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9829
Self-injurious behavior in Greek adolescents: the role of mental health problems and COVID-19 trauma
Published 2025-06-01“…While much research has focused on interpersonal trauma, the impact of non-interpersonal traumatic events—such as those stemming from the COVID-19 pandemic—remains less clear. Methods We investigated the associations between SIB, mental health difficulties, and COVID-19–related traumatic stress in a non-clinical sample of 5,612 Greek adolescents (55.4% female; mean age = 13.42 ± 0.96 years) from the Global Child and Adolescent Mental Health Study. …”
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9830
DNA methylation biomarker panels for differentiating various liver adenocarcinomas, including hepatocellular carcinoma, cholangiocarcinoma, colorectal liver metastases and pancreat...
Published 2024-11-01“…This study aimed to validate previously identified DNA methylation biomarkers that successfully differentiate between liver adenocarcinomas, including the two most common primary liver cancers, hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), as well as two common metastatic liver cancers, colorectal liver metastases (CRLM) and pancreatic ductal adenocarcinoma liver metastases (PCLM), and translate them to the methylation-sensitive high-resolution melting (MS-HRM) and digital PCR (dPCR) platforms. Methods Our study included a cohort of 149 formalin-fixed, paraffin-embedded tissue samples, including 19 CRLMs, 10 PCLMs, 15 HCCs, 15 CCAs, 15 colorectal adenocarcinomas (CRCs), 15 pancreatic ductal adenocarcinomas (PDACs) and their paired normal tissue samples. …”
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9831
Numerical and experimental evaluation of shear strength and consolidation properties of cohesive soils in high water table areas
Published 2025-03-01“…The numerical results from PLAXIS offered a more accurate understanding of soil behavior compared to the traditional Meyerhof and Vesic methods, highlighting the necessity of integrating advanced numerical techniques with conventional approaches. …”
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9832
Addition of PARP1-inhibition enhances chemoradiotherapy and thermoradiotherapy when treating cervical cancer in an in vivo mouse model
Published 2025-12-01“…The aim of our present study was to test efficacy of different combinations of treatment modalities radiotherapy, cisplatin, hyperthermia and PARP1-inhibitors using in vitro tumor models, ex vivo treated patient samples and in vivo tumor models.Materials and Methods: In vitro clonogenic survival curves (0–6 Gy) show that PARP1-i (4–5 M Olaparib) enhances both chemoradiotherapy (0.3–0.5 µM cisplatin) and thermoradiotherapy (42 °C for 1 h) in SiHa, CaSki and HeLa cells. …”
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9833
AP5Z1 affects hepatocellular carcinoma growth and autophagy by regulating PTEN ubiquitination and modulating the PI3K/Akt/mTOR pathway
Published 2025-05-01“…The functional and molecular mechanisms of AP5Z1 were studied using clinical sample analysis, Western blot (WB), immunohistochemistry (IHC), quantitative reverse-transcription polymerase chain reaction (qRT‒PCR), coimmunoprecipitation (Co-IP), cell proliferation assays, flow cytometry (FCM), autophagy assays, electron microscopy, mass spectrometry (MS), transcriptome analysis, and animal model experiments. …”
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9834
Construction of hot tumor classification models in gastrointestinal cancers
Published 2025-02-01“…‘Hot tumors’ with high levels of infiltration tend to respond better to immune checkpoint inhibitor (ICI) therapy, making them potential biomarkers for ICI treatment. Methods To explore potential biomarkers for predicting immunotherapy response and prognosis in GI cancers, we downloaded the gene expression profiles of seven GI cancers from The Cancer Genome Atlas (TCGA) database and characterized their TME, classifying the samples into hot/cold tumor subgroups. …”
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9835
Multi-omics integration identifies NK cell-mediated cytotoxicity as a therapeutic target in systemic lupus erythematosus
Published 2025-05-01“…Given the intricate clinical progression of SLE, it is imperative to explore novel avenues for precise diagnosis and treatment.MethodsPeripheral blood mononuclear cells (PBMC) were isolated from 6 SLE patients before and after treatment, 7 healthy controls and 7 disease controls. …”
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9836
Fluoride Release of Fresh and Aged Glass Ionomer Cements after Recharging with High-Fluoride Dentifrice
Published 2019-01-01“…This study aimed to evaluate F release from GICs before and after recharging with F-dentifrices and after aging process. Methods. Fifteen specimens of GICs (conventional, resin modified, and high viscosity) and composite resin were stored individually in a polystyrene tube containing 2 ml of deionized water (DW), with water replacement every 24 hours. …”
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9837
Workforce and welfare: Linking child protection staffing levels to recurrence risk
Published 2025-10-01“…Annual levels of evaluation staffing levels for the CP agencies were extracted for the same time period and linked to the administrative dataset. Methods: Using a multilevel model, this study tested whether the number of CP evaluation workers per capita in a family's service delivery area was correlated to the likelihood of recurrent substantiation. …”
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9838
Long-Term Ketogenic Diet Induces Metabolic Acidosis, Anemia, and Oxidative Stress in Healthy Wistar Rats
Published 2020-01-01“…All rats were caged individually and received 30g of either standard or high-fat-low-carbohydrate pellets. The experiment was carried out for 60 days before the blood samples were taken and analyzed to obtain blood gas, cell counts, organ biomarkers, and plasma antioxidant superoxide dismutase (SOD) levels. …”
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9839
Increasing the availability of long-acting reversible contraception and medical abortion in primary care: the Australian Contraception and Abortion Primary Care Practitioner Suppor...
Published 2022-12-01“…Changes in the knowledge attitudes and practices will be gleaned through an online survey with 500 individuals from each professional group at baseline and 12 months after members have joined AusCAPPs; and experiences of the AusCAPPS Network will be evaluated using interviews with the project team plus a convenience sample of 20 intervention participants from each professional group. …”
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9840
Escalating doses of intravenous APAC demonstrate antithrombotic effect in pigs
Published 2025-06-01“…We aimed to assess safety and escalating intravenous (i.v.) doses of APAC on hemostasis using a large animal model. Methods We studied escalating APAC boluses (0.15–1.5 mg/kg; n = 11) and their reversal in anesthetized pigs for pharmacodynamics using functional coagulation testing. …”
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