Toward an intersectional equity approach in social–ecological transformations by Paula Andrea Sánchez-García, Krisztina Jónás, Kara E. Pellowe, Hanna Ekström, Mary Scheuermann, Lasse Loft

“…We suggest advancing beyond these methods by integrating intersectional analysis into the distributive, procedural, and recognition aspects of equity when examining social–ecological transformations. …”
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Impact of submicron Nb_{3}Sn stoichiometric surface defects on high-field superconducting radiofrequency cavity performance by Sarah A. Willson, Aiden V. Harbick, Liana Shpani, Van Do, Helena Lew-Kiedrowska, Matthias U. Liepe, Mark K. Transtrum, S. J. Sibener

“…These findings have technical implications that will help guide improvements to Nb_{3}Sn fabrication procedures. Our outlined experiment-informed theoretical methods can assist future studies in making additional key insights about Nb_{3}Sn stoichiometric defects that will help build the next generation of SRF cavities and support related superconducting materials development efforts.…”
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Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech by Julianna Olah, Win Lee Edwin Wong, Atta-ul Raheem Rana Chaudhry, Omar Mena, Sunny X. Tang

“…We adopted online data collection methods to collect 20 min of speech and demographic information from individuals. …”
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eIF5A downregulated by mechanical overloading delays chondrocyte senescence and osteoarthritis by regulating the CREBBP-mediated Notch pathway by Jialuo Huang, Jianrong Zheng, Jianbin Yin, Rengui Lin, Junfeng Wu, Hao-Ran Xu, Jinjian Zhu, Haiyan Zhang, Guiqing Wang, Daozhang Cai

“…Aims: To examine how eukaryotic translation initiation factor 5A (eIF5A) regulates osteoarthritis (OA) during mechanical overload and the specific mechanism. Methods: Histological experiments used human bone samples and C57BL/6J mice knee samples. …”
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Bioabsorbable Poly(vinyl alcohol)–Citric Acid Dressings: Wound Healing Studies in an Experimental In Vivo Model by Jonalba Mendes Pereira, Emilia Angela Lo Schiavo Arisawa, Antônio Luiz Martins Maia Filho, José Figueredo-Silva, Nicoly Alves, Carolina Hahn da Silveira, Lucia Vieira

“…This PVA-CA combination promotes crosslinking, increases the dressing capacity of absorption and confers heal-ing properties due to the citric acid antioxidant action. Methods: The dressing was tested in a quantitative experiment on 1.9 cm acute dermatological lesions in rats (<i>n</i> = 12), com-paring the PVA-CA-treated group with the untreated control group (CG). …”
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Tea and other diet-related practices in relation to sleep health in midlife women from Mexico City: qualitative and quantitative findings by Astrid N. Zamora, Astrid N. Zamora, Elizabeth F. S. Roberts, Lilian Sharp, Catherine Borra, Jennifer Lee, Martha M. Téllez-Rojo, Karen E. Peterson, Libni A. Torres-Olascoaga, Alejandra Cantoral, Erica C. Jansen, Erica C. Jansen

“…Informed by qualitative analyses, a secondary aim was to examine associations between tea and sleep duration in a broader cohort.Materials and methodsWe conducted a cross-sectional study that entailed in-depth ethnographic interviews about sleep and other behaviors, including diet, with a purposive sample of 30 women from the ELEMENT cohort. …”
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Exploration of the biodiversity and mining novel target genes of Listeria monocytogenes strains isolated from beef through comparative genomics analysis by Bo Zhang, Wenjie Sun, Xiaoxu Wang, Honglin Ren, Yang Wang, Shaohui Hu, Chengwei Li, Yuzhu Wang, Jiaqi Hou, Xueyu Hu, Ruoran Shi, Yansong Li, Shiying Lu, Qiang Lu, Zengshan Liu, Pan Hu

“…Moreover, in the artificial contamination experiment, the bglF_2 gene was able to effectively detect L. monocytogenes in beef samples. …”
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Cardiac and Electrodermal Responses to Threats: Modulation by Childhood Sexual Abuse History by Mariana Xavier, Arthur V. Machado, Eliane Volchan, Letícia Oliveira, Liana Catarina L. Portugal, Gabriela G.L. Souza, Fátima S. Erthal, Raquel M. Gonçalves, Camila M.F. Gama, Rita de Cássia S. Alves, Izabela Mocaiber, Mirtes G. Pereira

“…In this study, we explored how autonomic reactivity to threats is influenced by the history of CSA in a nonclinical sample. Methods: Participants were undergraduate students with no current diagnosis of cardiovascular disease or mental disorders. …”
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The Manitoba Personalized Lifestyle Research (TMPLR) study protocol: a multicentre bidirectional observational cohort study with administrative health record linkage investigating... by Navdeep Tangri, Dylan Mackay, Rebecca C Mollard, Matthew Granger, Sharon Bruce, Heather Blewett, Jared Carlberg, Todd Duhamel, Peter Eck, Patrick Faucher, Naomi C Hamm, Ehsan Khafipour, Diana McMillan, Semone Myrie, Amir Ravandi, Meghan Azad, Peter JH Jones

“…The objective of The Manitoba Personalized Lifestyle Research study is to understand how these lifestyle factors interact with each other and with other factors, such as an individual’s genetics and gut microbiome, to influence health.Methods An observational study of adults, with extensive phenotyping by objective health and lifestyle assessments, and retrospective assessment of early life experiences, with retrospective and prospective utilisation of secondary data from administrative health records.Study population A planned non-random convenience sample of 840 Manitobans aged 30–46 recruited from the general population, stratified by sex (equal men and women), body mass index (BMI; 60% of participants with a BMI&gt;25 kg/m2) and geography (25% from rural areas). …”
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Prognostic significance and immune infiltration analysis of HMGA2 in endometrial cancer by Peng Jiang, Jiaxin Yu, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Chunxia Gong, Hangkun Yu, Yi Luo, Zhuoying Hu

“…However, its roles in prognostication and tumor immune microenvironment modulation in endometrial cancer (EC) remain incompletely defined.MethodsWe systematically analyzed HMGA2 expression patterns and clinical prognostic value in EC using bioinformatics strategies, including TCGA and GTEX data mining, as well as single gene expression analysis. …”
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Age-related differences in borderline personality disorder traits and childhood maltreatment: a cross-sectional study by GuoRong Li, Yong Lin, Yun Xu, Yong Zhou, YanYan Wei, LiHua Xu, XiaoChen Tang, Zixuan Wang, Qiang Hu, JiJun Wang, HaiSu Wu, ZhengHui Yi, TianHong Zhang

“…IntroductionThis study investigates age-related differences in Borderline Personality Disorder (BPD) traits and childhood maltreatment (CM) experiences among adolescents, young adults, and older adults within a clinical sample.MethodsA cross-sectional design was employed, involving 2029 outpatients aged 15-50 years from the Shanghai Mental Health Center. …”
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Optimized AI and IoT-Driven Framework for Intelligent Water Resource Management by Mahmoud Badee Rokaya Mahmoud, Dalia Ismaeil Ibrahim Hemdan, Samah Hazzaa Alajmani, Raneem Yousif Alyami, Ghada Elmarhomy, Hassan Hashim, El-Sayed Atlam

“…Additional performance measures comprise precision (89.0%), recall (95.2%), F1-score (0.92), and inference speed (0.003 ms/sample). Although quantization has reduced the computational overhead, we still see a 13.02% increase in the model size as seen in Experiment 6, leading to a trade-off that needs to be optimized further. …”
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Una aproximación al ámbito laboral de las mujeres trans desde una perspectiva de la intervención social by Alejandro Hernández-Melián

“…For this purpose, a qualitative method is used through semi-structured interviews, with a total sample of six participants from different Autonomous Communities of Spain and from programs managed both from the public and the Third Social Sector. …”
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The mechanisms of Brucea javanica in the treatment of oral squamous cell carcinoma: a network pharmacology, molecular docking, and experimental study by MingKang Li, Juan Zhan, YiHan Lai, YuJie Ma, HongCheng Wei, Lin Jiang, JuanJuan Zha, YiSen Shao, Wei Wang

“…Abstract Objective To elucidate the potential targets and mechanisms of Brucea javanica in the treatment of oral squamous cell carcinoma (OSCC) through network pharmacology and molecular docking, supported by clinical data and in vitro experiments. Methods Potential targets of Brucea javanica and OSCC-related disease targets were identified via the TCMSP, GeneCards, and OMIM databases. …”
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Effect of sun dry brewer spent yeast on chemical composition, in vitro digestibility, and ruminal degradation kinetics of wheat straw by Geberemariyam Terefe, Mulugeta Walelgne, Dereje Fekadu, Getu Kitaw, Mesfin Dejene, Aeimro Kehaliu, Bethlehem Mekonnen, Yohannse Habteyesus

“…This study was conducted to evaluate the effect of DBSY on the chemical composition, in vitro digestibility, and in situ degradability of wheat straw (WS). Methods Liquid brewer spent yeast (BSY) and water was mixed at a ratio of 1:5, respectively. …”
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Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins by Min Luo, Min Luo, Ying Tang, Jing Qiu, Jing Qiu, Kai Yang, Kai Yang, WenJing Dai, WenJing Dai, EnRong Fang, EnRong Fang

“…This study explores causal links between circulating proteins and COPD, identifies potential drug targets, and examines the role of lifestyle factors.MethodsUsing a large proteomics database and a public dataset of 394,244 samples (21,617 COPD cases and 372,627 controls), 4,907 proteins were associated with COPD. …”
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Unique Function in Cancer Stemness and Prognostic Significance of <i>EMX2</i> in Esophageal Squamous Cell Carcinoma by Shoichi Fumoto, Keiji Tanimoto, Takuya Noguchi, Jun Hihara, Eiso Hiyama, Keiko Otani, Megu Ohtaki, Yutaka Shimada, Masahiko Nishiyama, Keiko Hiyama

“…In this study, we focus on the expression profile and the prognostic significance of EMX2 in esophageal squamous cell carcinoma (ESCC). <b>Methods/Results:</b> The expression levels of <i>EMX2</i> in clinical ESCC samples varied and appeared to be lower than those in adjacent normal tissues. …”
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Impact of COVID-19 on mobility and participation of older adults living in Hamilton, Ontario, Canada: a multimethod cohort design protocol by Luciana G Macedo, Marla K Beauchamp, Heather Keller, Nazmul Sohel, Renata Kirkwood, Brenda Vrkljan, Elisabeth Vesnaver, Janie Astephen-Wilson, Tara Noble, Nicholas Dietrich, Paula Gardner, K Bruce Newbold, Darren Scott

“…This protocol details a multimethod cohort design undertaken to describe short-term and medium-term changes to the mobility and participation of older Canadians living in the community rather than retirement facilities during the COVID-19 pandemic.Methods and analysis A longitudinal telephone (or online)-administered survey is being conducted with a random sample of older adults living within 20 km of McMaster University, Hamilton, Ontario, Canada, identified from census dissemination areas. …”
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Efficacy and potential pharmacological mechanism of Astragalus-Salvia miltiorrhiza combination in diabetic nephropathy: integrating meta-analysis, network pharmacology, molecular d... by Huiyu Liang, Zedong Chen, Mingmin Zhu, Jingying Zhong, Shufan Lin, Jianfeng Chen, Jing Yuan, Pingping Jiang, Xiaoshan Zhao, Ya Xiao

“…The Astragalus and Salvia miltiorrhiza couplet medicines (AS) are commonly employed in DN clinical treatment in China, but their clinical efficacy and potential pharmacological mechanisms are yet to be evaluated.Material and Methods A meta-analysis of 15 studies involving 1,443 patients was conducted. …”
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Dose-dependent effects of testosterone on proteins related to nitric oxide signaling pathway and trophic factors in the spinal cord of adolescent trained rats by Katarzyna Nierwińska, Katarzyna Nierwińska, Konstancja Grabowska, Małgorzata Chalimoniuk, Sławomir Jagsz, Józef Langfort, Andrzej Małecki, Marta Nowacka-Chmielewska

“…At the end of the experiment, spinal cord samples were collected for further evaluation.Results and DiscussionMajor findings from the study are that a high dose of testosterone increases proteins related to the NO signaling pathway (eNOS, nNOS, CGβ1, PKC), but decreases trophic factors (BDNF, VEGF) and p-Akt. …”
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