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9381
Integrative analysis of Ewing’s sarcoma reveals that the MIF-CD74 axis is a target for immunotherapy
Published 2025-01-01“…Therefore, more effective treatment options are urgently needed. Methods Since novel immunotherapies may address this need, we performed an integrative analysis involving single-cell RNA sequencing, cell function experiments, and humanized models to dissect the immunoregulatory interactions in EwS and identify strategies for optimizing immunotherapeutic efficacy. …”
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9382
Intensification of the process of beverage production from dry fruit raw material of the Republic of Adygea
Published 2019-09-01“…The market of soft drinks is expanding due to the development of a new type of product-functional drinks.Functional drinks are characterized by high nutritional and taste value due to the content of easily digestible carbohydrates, mineral compounds, organic acids and biologically active substances.The research is based on the traditional technology used at the enterprises of the Republic for the production of “Shipovnik” and “Boyaryshnik” functional drinks and one of the most promising ways to intensify extraction using ultrasonic treatment.During the experiment extraction schemes from dry fruit raw materials have been studied and the possibility of their use as resource-saving technologies in the production of drinks from dried rosehips and hawthorn have been evaluated.The research methods used: determination of biologically active substances using capillary electrophoresis using Capel 105 “M” system, determination of the content of extractives using an IRF-454B2M refractometer, and an Expert-001 ionometer has been used to determine the pH.Microbiological parameters of the studied samples have been determined according to GOST R 50474-93 and GOST 10444.12-88. …”
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9383
Perspectives of people with cystic fibrosis considering parenthood surrounding preconception and prenatal genetic counseling and testing
Published 2025-05-01“…Methods: We conducted and recorded semi-structured telephone interviews with participants. …”
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9384
Thermogravimetric investigations of cream with minoxidil
Published 2016-12-01“…However the mass of the example to the end of experiment practically didn’t change (decrease on 0,32%). …”
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9385
Application of salmonella phage to reduce in-vitro and in-vivo colonization of salmonella enteritidis and salmonella typhi
Published 2024-12-01“…The purpose of this study was to prepare a proper Salmonella phage therapy candidate to be used against pathogenic Salmonella enteritidis and Salmonella typhi. Methods: We used clinical isolates of Salmonella typhi and Salmonella enteritidis as host bacteria, to isolate Salmonella-specific phages from raw sewage water in four locations (Bahrka, Farmnbaran neighborhoods, Korey and Shaqlawa towns) in Erbil district. …”
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9386
The control effect of the pore and fracture characteristics of tectonic coal assisted by the triaxial stress permeability system on permeability
Published 2025-04-01“…To achieve this, a triaxial stress permeability system and deep learning (DL) techniques are employed to conduct experiments on tectonic coal samples, enabling the measurement of permeability variations under different stress conditions. …”
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9387
Pregnancy in HIV clinical trials in Sub Saharan Africa: failure of consent or contraception?
Published 2013-01-01“…We designed a qualitative study to explore the factors contributing to high pregnancy rates among participants in two HIV clinical trials in Sub-Saharan Africa.<h4>Methods</h4>Female and male participants enrolled in one of two clinical HIV trials in south-west Uganda were approached. …”
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9388
COVID-19 pandemic, domestic violence, and victims’ access to services: findings from a survey of victim service providers in the US
Published 2025-08-01“…Abstract Background This study aims to explore the relationship between the COVID-19 pandemic and domestic violence victims’ help-seeking from victim service providers in the United States using the framework of Routine Activities Theory. Methods The analysis is based on primary data collected from an online survey that represents a national sample of organizations serving domestic violence victims across the states and territories of the United States. …”
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9389
“Just a second, mommy’s here”: the impact of mothers’ smartphone use on children’s affect regulation and the quality of mother–child interactions
Published 2025-07-01“…Additionally, we investigated the associations between mothers’ behaviors to maintain contact with their children during smartphone use and their children’s affect regulation.MethodsThe experiment consisted of two counterbalanced phases: the free play phase and the interruption phase, in which mothers were replying to standardized text messages in the presence of their children. …”
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9390
My husband is my responsibility:” motivations and activities of informal caregiving for patients with chronic diseases in Uganda
Published 2025-05-01“…Therefore, this study explored the motivations to becoming informal caregivers of patients with chronic diseases in Uganda. Methods Focus group discussions (FGDs) were conducted among 33 informal caregivers of patients with chronic diseases at Mbarara Regional Referral Hospital in Uganda. …”
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9391
Electron Microscopic Retina Changes in Rabbit Eyes with Perfluorocarbon Liquids Intravitreal Tamponade
Published 2019-03-01“…Analysis of electron microscopic changes in rabbit eyes with intravitreal tamponade of perfluorocarbon liquids (PFCL) (perfluoro-1,3-dimethylcyclohexane and perfluorodecalin). Material and Methods. The study was performed on Chinchilla breed rabbits. 25G vitrectomy with PFCL intravitreal tamponade was performed on 12 eyes of 6 rabbits (perfluorodecalin (Bausch+Lomb «Dk-line», USA) and perfluoro-1,3-dimethylcyclohexane (ZAO “Optimedservis”, Russia). …”
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9392
Novel cuproptosis-related lncRNAs risk model to predicting prognosis and guiding immunotherapy for OSCC patients
Published 2025-05-01“…However, as a new research hotspot, the cuproptosis-related lncRNAs (CRLs) associated with regulation in oral squamous cell carcinoma (OSCC) patients are currently not well understood. Methods Long noncoding RNA (lncRNA) data were downloaded from the Cancer Genome Atlas database (TCGA). …”
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9393
Imidacloprid decreases energy production in the hemolymph and fat body of western honeybees even though, in sublethal doses, it increased the values of six of the nine compounds in...
Published 2025-01-01“…Therefore, our goal was to answer which of these two phenomena occurs in the hemolymph/fat body and at what doses of imidacloprid.<h4>Methods</h4>concentrations/activities of respiratory/citric cycle compounds (acetyl-CoA, IDH-2, AKG, succinate, fumarate, NADH2, COX, UQRC, and ATP) were compared in the hemolymph and fat bodies of nurse workerbees sampled from honeybee colonies fed with diets containing 200 ppb (IM-200), 5 ppb (IM-5; sublethal), and 0 ppb of IM in a field experiment.…”
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9394
The technology development for the complex Api-phyto product “Apised” in the form of capsules with the restorative and sedative action
Published 2017-12-01“…The aim of the study is to substantiate and experimentally develop the technology for the complex api-phyto product “Apised” (which is used to treat nervous disorders and the psycho-emotional stress in extreme conditions, in particular in sports medicine) in the form of gelatin capsules in pharmacy conditions and in conditions of industrial production based on the pharmaceutical-technological and physical-chemical studies. Materials and methods. As the research objects the experimental samples of “Apised” capsules, as well as their mixtures of masses for encapsulation were used. …”
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9395
"We lost a lot, but something good came out of it too:" Exploring the impact of the COVID-19 pandemic on the mental wellbeing of British Muslim Pakistani women with family responsi...
Published 2023-01-01“…<h4>Methods</h4>Qualitative interviews with women were conducted via telephone using a semi-structured topic guide. …”
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9396
Leptin Enhances Nitric Oxide Production and Decreases Blood Flow in Rat Skeletal Muscle
Published 2022-06-01“…Hemodynamic parameters: mean arterial pressure, heart rate and blood flow were recorded during the experiment and at the end blood samples for biochemical analyses of leptin and nitrite/nitrate levels and gastrocnemius muscle tissues from the right hindlimb for NOS distribution were taken. …”
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9397
A novel ACE inhibitory peptide from Pelodiscus sinensis Wiegmann meat water-soluble protein hydrolysate
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9398
The psychologically rich life questionnaire: Italian validation and exploration of its relationships with mindfulness, self-compassion, and cognitive fusion within the health psych...
Published 2025-02-01“…Psychological richness, characterized by diverse and interesting experiences, complements the hedonic and eudaimonic dimensions of well-being, offering a broader perspective on what constitutes a meaningful life.MethodsAfter a subsequent back translation procedure, the resulting questionnaire version was checked for the comprehensibility of the items. …”
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9399
The Relationship between Bullying and Emotional State among Undergraduate Nursing Students: A Cross-Sectional Correlation Study
Published 2023-01-01“…The study investigated the relationship between bullying and the emotional state of undergraduate nursing students. Methods. The study used a cross-sectional correlation design with a sample of 286 undergraduate nursing students from multiple nursing colleges located in the western region of Saudi Arabia. …”
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9400