The validity of the Meaning in Life in Persons with Dementia Questionnaire (MIND) by Torgeir Sørensen, Sverre Bergh, Knut Asbjørn Hestad, Ingvild Hjorth Feiring, Lars Johan Danbolt, Bjørn Lichtwarck

“…This study aims to validate the newly developed Meaning in Life in Persons with Dementia Questionnaire (MIND) for use in nursing home residents.MethodsWe included 116 participants with dementia from 34 nursing homes in Eastern Norway. …”
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PDS5B positively regulates PTEN by binding to YTHDC1 to inhibit the malignant progression of endometrial carcinoma by Hanyi Wang, Yaping Qian, Jie Li, Qianyun Gao

“…The expression of PDS5B was verified by western blot and qRT-PCR in cell and tissue samples. The effects of PDS5B overexpression on EC cell proliferation, invasion and apoptosis, as well as the interaction of PDS5B with YTHDC1 and the regulation of PTEN stability were further explored by in vitro experiments. …”
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Protective effects of chlorogenic acid against glyphosate-induced organ and blood toxicity in Wistar rats by Türkmen Ruhi, Birdane Yavuz Osman, Atik Orkun, Demirel Hasan Huseyin, Baser Durmus Fatih

“…Our study examines the efficacy of chlorogenic acid (CGA) in alleviating the toxicity of a glyphosate-based herbicide (GBH) in 42 Wistar rats across six groups of seven animals receiving either no treatment (control), CGA alone (50 mg/kg), GBH alone (800 mg/kg), or their combinations varying three CGA doses (12.5, 25, or 50 mg/kg) (CGA12.5+GBH, CGA25+GBH, and CGA50+GBH, respectively) by oral gavage over 49 days in a row. At the end of the experiment, samples of blood, brain, heart, liver, and kidney tissues were collected and analysed for oxidative stress indicators (MDA, GSH, SOD, CAT), oxidative DNA damage (8-OHdG), liver and kidney function markers (AST, ALT, ALP, urea, and creatinine) as well as for histopathological changes. …”
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Comparative effects of different loads of aerobic exercise on lipid metabolism in MASLD rats: a perspective from the gut-liver axis by Deng Dongkun, Jiang Qingfeng, Li Chang, Lin Yunhua, Shi Jiaming, Liu Yufei, Xu Lin

“…At the conclusion of the experiment, blood, liver, and ileum samples were collected for analysis of the rats’ baseline conditions, hepatic lipid metabolism, bile acid pathway and gut microbiota, and synthesis of analyses.ResultsThe development of lipid metabolism disorders, insulin resistance, and hepatic steatosis in MASLD rats was improved to different degrees in all three exercise modes. …”
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COMPARATIVE EVALUATION OF THE COMMON TOXIC PROPERTIES OF THE ANTIBIOTIC AMOXICILLIN OF THE RUSSIAN AND IMPORTED PRODUCTION (EXPERIMENTAL HYGIENIC STUDIES) by Лариса Геннадьевна Горохова, Анна Геннадьевна Жукова

“…The acute toxicity study did not reveal a difference between the Russian amoxicillin and the comparison drug, the median lethal dose of both drugs exceeded 10,000 mg/kg, which classifies them as low-toxic substances. In a sub-chronic experiment, the presence of a toxic effect on hepatocytes was revealed when large doses of the drug were administered: the activity of AsAT, AlAT was increased (more significantly – by 64 % - when using an imported sample), total and conjugated bilirubin, triglycerides were raised, total serum protein was decreased. …”
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LIMA1 inhibits cisplatin resistance and malignant biological behavior of bladder cancer cells by suppressing the Wnt/β-catenin pathway by Zhong Lv, Shuchen Zhao, Haoran Wu

“…Abstract Objective This study aimed to explore the effect of LIM domain and actin binding 1 (LIMA1) on bladder cancer (BCa) cells and to investigate its underlying molecular mechanisms. Methods The expression of LIMA1 gene in clinical BCa tissue samples and BCa cell models was detected using real-time quantitative PCR and western blot. …”
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Effects of high intensity training and high volume training on endothelial microparticles and angiogenic growth factors. by Patrick Wahl, Felix Jansen, Silvia Achtzehn, Theresa Schmitz, Wilhelm Bloch, Joachim Mester, Nikos Werner

“…As endurance exercise affects the endothelium, the objective of the study was to examine levels of EMP and angiogenic growth factors following different endurance exercise protocols.<h4>Methods</h4>12 subjects performed 3 different endurance exercise protocols: 1. …”
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A Qualitative Study of Service Provision for Alcohol Related Health Issues in Mid to Later Life. by Catherine Haighton, Graeme Wilson, Jonathan Ling, Karen McCabe, Ann Crosland, Eileen Kaner

“…<h4>Methods</h4>Qualitative interviews (n = 24, 12 male/12 female, ages 51-90 years) and focus groups (n = 27, 6 male/21 female, ages 50-95 years) were carried out with a purposive sample of participants who consumed alcohol or had been dependent.…”
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Transcriptomic characterization of the functional and morphological development of the rumen wall in weaned lambs fed a diet containing yeast co-cultures of Saccharomyces cerevisia... by Zixuan Xu, Lan Yang, Hui Chen, Pengxiang Bai, Xiao Li, Dacheng Liu

“…IntroductionIn lambs, the function of the rumen is incompletely developed at weaning, and the inclusion of yeast cultures in the diet can profoundly influence the morphological and functional development of the rumen.MethodsIn this study, the effects of Saccharomyces cerevisiae and Kluyveromyces marxianus (NM) yeast co-cultures on ruminal histomorphology were assessed, and corresponding transcriptomic changes within the rumen epithelium were identified. …”
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The Interplay of Anxiety, Stress, and Depressive Symptoms among Sexual Orientations in Asian Populations by Passakorn Suanrueang

“…However, few studies have presented results on this interlink based on sexual orientation. Methods: This study involved examining the association between stress, anxiety, and depressive symptoms, and the ability of anxiety and stress to predict depressive symptoms in a sample of 21,972 volunteer participants from Asian countries (Open-Source & Open-Source Psychometrics Project), who self-reported their mental health experiences in questionnaires on an online platform using the DASS-42 self-report questionnaire. …”
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A Study of the Differences in the Gas Diffusion and Migration Characteristics of Soft and Hard Coal in High Gas Coal Seams by Anying Yuan

“…This study conducted gas desorption experiments on both soft and hard coal samples and found that the initial gas desorption speed of the soft coal was significantly higher than that of the hard coal. …”
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Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes. by Taole Li, Jifeng Guo

“…We aimed to identify the ferroptosis-related genes (FRGs) and construct competing endogenous RNA (ceRNA) networks to further assess the pathogenesis of PD.<h4>Methods</h4>Expression of 97 substantia nigra (SN) samples were obtained and intersected with FRGs. …”
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Cross-Receiver Radio Frequency Fingerprint Identification: A Source-Free Adaptation Approach by Jian Yang, Shaoxian Zhu, Zhongyi Wen, Qiang Li

“…Our theoretical analysis provides a solid foundation for the generalization performance of SCRFFI, which is corroborated by extensive experiments on real-world datasets, where under realistic noise and channel conditions, that CSCNet significantly improves recognition accuracy and robustness, achieving an average improvement of at least 13% over existing methods and, notably, a 47% increase in specific challenging cross-receiver adaptation tasks.…”
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Stress, Conscious Self-Regulation, and Examination Success in Engineering Students by Varvara I. Morosanova, Irina N. Bondarenko, Igor Yu. Tsyganov

“…The study involved 322 second-year students of a Moscow technical university specializing in information security (Mage = 19.22; SD = 4.64; 29% were female students). Methods. The students completed 4 questionnaires on the “Testograph” platform (https://www.testograf.ru) shortly before the exam session: Self-Regulation Profile (SRP-2020), Brief Acute and Chronic Stress (BACS), Perceived Stress Scale (PSS), Subjective and Objective Uncertainty Stress (SOUS) scale. …”
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CSF outflow from the human spinal canal: preliminary results from an anatomical specimen-based model by Radosław Rzepliński, Steven T. Proulx, Sylwia Tarka, Tomasz Stępień, Bogdan Ciszek

“…In this paper, we introduce an anatomical specimen-based preparation for studying spinal CSF outflow in humans and present preliminary results from our initial studies. Methods Unfixed anatomical specimens of the thoracolumbar spinal dural sac along with the spinal nerves were obtained from cadavers. …”
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Posttraumatic stress and depression in Yazidi refugees by Nasıroğlu S, Çeri V

“…The refugees were asked about preventive and risk factors that occurred before and after their immigration. Subjects and methods: The sample comprised 55 children and adolescents (30 males and 25 females) who were Yazidi refugees and had settled in the U&amp;ccedil;kuyular, Oğuz, Onbaşi, and Uğurca villages of Batman, Turkey. …”
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Exploring success in sub-acute hospital-to-home transitions for palliative patients: a descriptive qualitative study by Krystal Kehoe MacLeod, Taylor Shorting, Madeline McCoy, Shirley H. Bush, Genevieve Lalumière, Jill Rice, Sarina R. Isenberg

“…This formative assessment sought to better understand what constitutes a successful sub-acute hospital-to-home transition from the perspectives of health care providers connected to a sub-acute care facility in Ottawa, Canada, with reflections from a patient and a family caregiver. Methods Our descriptive qualitative study involved 13 virtual interviews and one virtual focus group between February and May 2023. …”
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The Effect of Canagliflozin on High-Density Lipoprotein Cholesterol and Angiopoietin-Like Protein 3 in Type 2 Diabetes Mellitus by Simo Liu, Jing Ke, Xiaotong Feng, Zongwei Wang, Xin Wang, Longyan Yang, Dong Zhao

“…This study is aimed at exploring the effect of SGLT2 inhibitor canagliflozin on lipid profile. Methods. This study was a single-center, open-label, nonrandomized, prospective study. …”
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Object detection model design for tiny road surface damage by Chenguang Wu, Min Ye, Hongwei Li, Jiale Zhang

“…Additionally, this study built a road dataset containing rich samples of tiny damage. Extensive comparative experiments are conducted on the collected dataset and a public dataset to validate the generalization performance of RSDD. …”
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Absence of EpCAM in cervical cancer cells is involved in slug induced epithelial-mesenchymal transition by Xian Liu, Qian Feng, Yanru Zhang, PengSheng Zheng, Nan Cui

“…In this study, the positive effect of Slug on promoting cell motility and metastasis in cervical cancer was further confirmed in this study. Methods RNA-Seq was performed to explore the potential molecules that participate in Slug-mediated EMT in cervical cancer cells. …”
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