The transcription factor FOXA1 upregulates PYCR1-mediated autophagy to suppress antitumor immunity in lung adenocarcinoma by Kui Liu, Xiaoyan Yang, Xuemei Tang, Bo Tang

“…PYCR1 can reinforce the proliferation of LUAD cells, but the function of PYCR1 in LUAD against the tumor immune response has not been fully elucidated. Methods The clinical significance of PYCR1 in LUAD and the relationship between PYCR1 expression and CD8+ T cell infiltration were examined by bioinformatics analysis. …”
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Cross-sectional study of the rates of military sexual trauma (MST) and associations with adverse mental health outcomes among UK female ex-service personnel: a study protocol by Dominic Murphy, Nicola T Fear, Marie-Louise Sharp, Tamara Obradovic

“…Introduction This study investigates the rates of military sexual trauma (MST) and its associations with adverse mental health among a sample of UK female ex-service personnel who served during the Iraq/Afghanistan eras.Methods and analysis Female ex-service personnel, who participated in the fourth phase (Phase 4) of the King’s Centre for Military Health Research (KCMHR) Health and Well-being Cohort Study (2022–2023) and consented to be recontacted for follow-up studies (n=295), are being invited to participate in an online questionnaire between July 2024 and February 2025. …”
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Manganese deficiency or dietary manganese(III) oxide nanoparticle supplementation: consequences for hematology, and intestinal and brain immunity in rats by Karolina Różaniecka-Zwolińska, Ewelina Cholewińska, Bartosz Fotschki, Jerzy Juśkiewicz, Katarzyna Ognik

“…IntroductionThe study aimed to determine the effect of manganese (Mn) exclusion from the mineral mixture added to the rat diet and replacing the recommended level of MnCO3 (65 mg Mn/kg diet) with Mn2O3 nanoparticles (Mn2O3NPs) in the diet on blood hematology and selected immunological indices of the blood, jejunum, and brain.MethodsThe experiment was conducted on twenty-four, Wistar rats divided into 3 equal groups. …”
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Root and Shoot Biomass Contributions to Soil Carbon and Nitrogen Under Grazing Intensity and Crop Rotation in an Integrated Crop–Livestock System by Lucas Aquino Alves, Fernando Arnuti, Leandro Bittencourt de Oliveira, Moacir Tuzzin de Moraes, Luiz Gustavo de Oliveira Denardin, Ibanor Anghinoni, Paulo César de Faccio Carvalho, Tales Tiecher

“…Soil depth layers (0–10, 10–20, 20–30, and 30–40 cm) were treated as sub-subplots. Root samples of Italian ryegrass, soybean, and maize were collected using the soil monolith method. …”
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Loneliness and Problematic Internet Use in Adolescents: The Mediating Role of Dissociation by Alessio Matiz, Fabio D’Antoni, Stefania Pascut, Rebecca Ciacchini, Ciro Conversano, Angelo Gemignani, Cristiano Crescentini

“…Methods. A cross-sectional design was used with 243 Italian high school students (69.1% females), from year 9 to 13 (age: M = 17.1, SD = 1.4 years), who participated in the study from January to June 2020. …”
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Anoikis in hepatocellular carcinoma: genetic alterations and immune microenvironment insights from single-cell and computational analysis by Bing Zhou, Jialing Zhang, Mingfeng Guo

“…PCR analysis of clinical samples confirmed the expression patterns of key gene KPNA2, and gene knockdown in cell experiments further validated its oncogentic role in HCC. …”
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Relaxation and physicomechanical characteristics of polyethylenes with different molecular weights by R. A. Alekhina, V. A. Lomovskoy, I. D. Simonov-Emel’yanov, S. A. Shatokhina

“…Determination of the influence of molecular weight on the modulus of elasticity, yield, strength, and retardation processes in polyethylene.Methods. We used vane samples (thickness: 4 mm; length: 100 mm; width.: 10 mm) made by injection molding at p = 60 MPa, T = 210 °C, τ = 15 s from the following polyethylenes: HDPE 27773 (Stavrolen, Lukoil, Russia); BorSafe HE3490-IM (Borealis, Austria; black); CRP 100 Hostalen (Basell Polyolefins, Netherlands; black); Stavrolen PE4PP-25B (Stavrolen, Lukoil, Russia; black). …”
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The effect of osteoarthritis exercise on pain and joint range of motion in osteoarthritis patients by Dewi Masyitah, Mashudi Mashudi, Bettywati Eliezer Tumanggor, Yessi Fadriyanti

“…The purpose of this study was to determine the effect of osteoarthritis exercise on pain and joint range of motion in osteoarthritis patients. Methods. The research design used a quasy experiment with a non-equivalent control group design approach. …”
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Positive effects of hearing and speech rehabilitation on lexical fund quality in hearing impaired children by Maletić-Sekulić Ivana, Veselinović Ivana, Jeličić Ljiljana, Šijan-Gobeljić Mirjana, Dragutinović Ninoslava

“…The aim of this study was to evaluate and compare the level of lexical development in hearing impaired children who are involved in the process of hearing and speech-language rehabilitation and who were amplified by hearing aids or cochlear implants. Methods. The sample consisted of 55 children aged 3–6 years, diagnosed with prelingual bilateral hearing impairment with a hearing threshold above 90 dB. …”
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Identification of key genes and signaling pathway in the pathogenesis of Huntington's disease via bioinformatics and next generation sequencing data analysis by Basavaraj Vastrad, Chanabasayya Vastrad

“…It is momentous to further examine the molecular pathogenesis of HD. Methods The HD next generation sequencing dataset GSE105041 was downloaded from the Gene Expression Omnibus (GEO) database. …”
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Development of a Rapid Epstein–Barr Virus Detection System Based on Recombinase Polymerase Amplification and a Lateral Flow Assay by Yidan Sun, Danni Tang, Nan Li, Yudong Wang, Meimei Yang, Chao Shen

“…Existing tests to detect EBV can be divided into three categories: nucleic acid assays, serological assays, and in situ hybridization assays. However, most methods are time-consuming, expensive, and not conducive to high-volume clinical screening. …”
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Identifying Diagnostic Biomarkers for Electroacupuncture Treatment of Rheumatoid Arthritis Using Bioinformatic Analysis and Machine Learning Algorithms by Sun Y, Dong G, Gao H, Yao Y, Yang H

“…This study aimed to identify potential diagnostic biomarkers for RA and elucidated the molecular targets of EA by using bioinformatics analysis and machine learning algorithms in peripheral blood samples.Methods: We obtained datasets from the Gene Expression Omnibus(GEO) database containing samples from RA patients (GSE15573) and from RA patients after EA treatment (GSE59526) for bioinformatics analysis. …”
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The Impact of Microscopic Pore Network Characteristics on Movable Fluid Properties in Tight Oil Reservoir by Jie Gao, Hu Wang, Xiaojun Ding, Qingxiao Yuchi, Qiang Ren, Bo Ning, Junxiang Nan

“…However, the research about fluid flow behavior was generally based on traditional methods, while the seepage characteristics from the pore-scale view are still a myth. …”
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High-quality DNA extraction for Desmodium gangeticum: A medicinal shrub of Shivalik Himalayas by Shiwani Singh, Maneesh S. Bhandari, Neeraj Dwivedi

“…Setting: This study was conducted under controlled laboratory environment at Manav Rachna Centre for Medicinal Plant Pathology, Department of Biotechnology, Manav Rachna International Institute of Research and Studies, Faridabad, India. Methods: Advanced techniques, commercial kits and rigorous modifications in existing DNA extraction buffer conditions and extraction protocols from both fresh and dried leaves are considered to optimise high-quality DNA isolation. …”
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Comparison of the effect of carbapenem and piperacillin-tazobactam on the development of fecal colonization with carbapenem resistant Enterobacterales by Tuğba Pamukçu, Gökhan Metan, Gökçen Telli, Gülçin Telli Dizman, Gülşen Hazırolan, Pınar Zarakolu, Murat Akova

“…Mice were treated for 14 days. Stool samples were collected for culture on certain days. …”
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Effect of Water Contamination on the Preservation of Vitamins in Juices by Vladimir P. Yustratov, Irina V. Timoshchuk, Alena K. Gorelkina, Natalia V. Gora, Nadezhda S. Golubeva, Elena V. Ostapova

“…The control sample contained water without contaminants, while the test samples involved trichloromethane, trichloroethylene, ethylene chloride, hydroxybenzene, and chlorophenol. …”
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An in-vitro comparison of fracture resistance of three CAD/CAM Ceramic materials for fabricating Veneer by Abdul Rahman Mohammed Saleh, Mena Al-Ani, Tuqa ALRawi, Ghufran Al-Edressi

“…Aims: This research aims to measure and compare the fracture resistance and modes of failure of the following three chemically varied computer-aided design/computer-aided manufacturing (CAD/CAM) ceramic veneering materials: IPS e.max CAD, Vita Enamic, and Shofu HC. Materials and methods: Twenty-seven sound human upper premolars were collected and stored in saline at room temperature until the experiment started and were assigned to three groups at random (n = 9). …”
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Influence of induced diabetes mellitus on hormonal profile of Lewis lung carcinoma in BALB/c Nude mice by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, A. I. Shikhlyarova, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, L. K. Trepitaki, N. D. Cheryarina

“…The assessment of diabetes mellitus (DM) effect on levels of sex hormones in tumor and peritumoral tissues in BALB/c Nude mice with Lewis lung carcinoma (LLC).Materials and methods. The study included 42 male and female BALB/c Nude mice aged 8–9 weeks weighing 21–22 g. …”
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Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases by Cheng-Cheng Deng, Xue-Yan Xu, Yan Zhang, Long-Can Liu, Xuan Wang, Jun-Yi Chen, Liu-Yi Yao, Ding-Heng Zhu, Bin Yang

“…In this study, we plan to investigate the intricate cellular landscape of immune cells in keloid, a paradigm of fibrotic skin diseases.MethodsCD45+ immune cells were enriched by fluorescence-activated cell sorting. …”
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Association of asthma and allergy history with premenstrual symptom severity in young adult women by Isabella Caruso, Donghao Lu, Sofija Zagarins, Elizabeth Bertone-Johnson

“…A sample of participants (n = 287) provided blood samples to evaluate inflammatory factor levels. …”
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