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8481
Curcumin exerts protective effects against valproic acid-induced testicular damage through modulating the JAK1/STAT–3/IL–6 signaling pathway in rats
Published 2025-02-01“…Materials and Methods: Male Wistar–Albino rats (n=28, 250–300 g) were randomly divided into four groups: Control (1 ml saline, oral), VPA (500 mg/kg, IP), CUR (200 mg/kg, oral), or VPA+CUR (500 mg/kg, VPA, IP plus 200 mg/kg CUR, oral). …”
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8482
Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway
Published 2025-07-01“…However, whether there exist critical long non-coding RNAs (lncRNAs) responsible for BC pathogenesis and representing promising candidates for combined targeted therapy remains an issue. Methods Public databases and bioinformatic methods were used to identify lncRNAs abnormally expressed among different subtypes of BC. …”
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8483
New forms of physical education in older preschoolers in the context of development intellectual and creative spheres of personality
Published 2025-06-01“…Methods. The study used various methods, such as structured analysis of outdoor games, questionnaires, observation, testing, pedagogical experiment and statistical processing of the data obtained. …”
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8484
Effectiveness of Common Beans Protein Extract (Phaseolus Vulgaris) as a Natural Coagulant in Purification of Portable Water.
Published 2023“…In this study, the application of extracts from common bean seeds (Phaseolus Vulgaris) as natural coagulants during purification of drinking water was investigated. One sample of water was used in the experiments. The water Sample was collected was collected in calm weather conditions. …”
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8485
Implementing the Kids’ Athletics Program in the System of Increasing the Level of Physical Performance of Youth
Published 2025-01-01“…The objective of this study was to verify the impact of the IAAF project “Kids’ Athletics” on the physical performance of pupils in primary education through the design and implementation of an athletics program. Materials and methods. The present study was conducted using a two-group non-concurrent experiment, in which the experimental group (decimal age 8.64 years) consisted of 50 probands and the control group (decimal age 8.55 years) consisted of 60 probands aged 8-9 years. …”
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8486
Zircon luminescence dating revisited
Published 2024-12-01“…<p>Luminescence dating plays a pivotal role in Quaternary science, yet ongoing methodological challenges persist in refining the temporal range, accuracy, and precision of luminescence methods. Our contribution revisits zircons as potential alternative dosimeters to quartz, feldspar, or calcite for routine dating applications. …”
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8487
Metabolomics Analysis of the Mechanism of Yuquan Capsules in the Treatment of T2DM Rats Using UPLC/MS
Published 2025-03-01“…The blood, kidney, pancreas, and liver tissue samples were collected at the end of the experiment. …”
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8488
FCN3 Can Serve as A Potential Biomarker for Prognosis and Immunotherapy of Lung Squamous Cell Carcinoma
Published 2025-02-01“…This study employed bioinformatics methods to analyze LUSC samples from The Cancer Genome Atlas (TCGA) database. …”
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8489
Cellular hierarchy framework based on single-cell and bulk RNA sequencing reveals fatty acid metabolic biomarker MYDGF as a therapeutic target for ccRCC
Published 2025-06-01“…The function of the selected genes in FAM was validated through clinical samples and cellular functional experiments.ResultsThe results revealed significant upregulation of FAM in malignant epithelial cells. …”
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8490
Ultra-sensitive detection of transposon insertions across multiple families by transposable element display sequencing
Published 2025-03-01“…Results We present a TE display sequencing approach that leverages target amplification of TE extremities to detect non-reference TE insertions with high specificity and sensitivity, enabling the detection of insertions at frequencies as low as 1 in 250,000 within a DNA sample. Moreover, this method allows the simultaneous detection of insertions for distinct TE families, including both retrotransposons and DNA transposons, enhancing its versatility and cost-effectiveness for investigating complex “mobilomes.” …”
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8491
A cost-effective protocol for detecting fluorescent microplastics in arable soils to study redistribution processes
Published 2025-06-01“…Understanding microplastics' (MPs) transport from soils to aquatic ecosystems is challenging due to labor-intensive detection methods, especially in large-scale plot experiments analyzing surface runoff and soil erosion. …”
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8492
FPR1 affects acute rejection in kidney transplantation by regulating iron metabolism in neutrophils
Published 2025-01-01“…This paper intends to investigate the possible mechanisms of neutrophil involvement in acute rejection in renal transplantation. Methods Samples were analyzed for their relationship with immune cells using CIBERSORT. …”
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8493
The effect of chlorin e<sub>6</sub> drug on platelet aggregation activity
Published 2019-10-01“…The goal of the study is to evaluate the effect of Radachlorin (OOO “RADA-PHARMA”, Russia) (RC) on platelet aggregation in ex vivo and in vivo experiments. The experiments were conducted on male Wistar rats. …”
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8494
Impact of Instructional Program on Nurses for Preventive Measures of Hepatitis (B and C) Infection Control in Medical City Hospitals
Published 2014-08-01“…Objectives: the study aims to: 1- Assess the nurses knowledge and practices about preventive measures of Hepatitis (B and C) Infection Control. 2- Evaluate the impact of instructional program on nurses knowledge and practices about preventive measures of Hepatitis (B and C) Infection Control. 3- Find out the relationship between impact of instructional program and nurses age, level of education, and year of experiences. Methodology :A quasi-experimental design study was carried out at Baghdad teaching hospital and Ghazi Al-Hareri for Specialist Surgeries hospital, during the period of June, 20th 2012 to June, 28th 2013, the study samples was composed of (60) nurses who working in the surgical ward unit, those nurses are divided equally into the study and the control groups. …”
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8495
Gender issues in taekwondo
Published 2024-01-01“…Based on qualitative coding methods, the final version of the coding tree identified three areas and five categories, with corresponding dimensions of gender issues in taekwondo. …”
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8496
The diagnostic accuracy of PTSD assessment instruments used in older adults: a systematic review
Published 2025-12-01“…Background: As the number of older adults increases worldwide, understanding their mental health is crucial, including the impact of traumatic experiences that can lead to posttraumatic stress disorder (PTSD). …”
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8497
Oil spill cleanup using EDTA-coated magnetite magnetic nanoparticles
Published 2024-12-01“…This study adopted a straightforward and economical method utilizing iron oxide magnetic nanoparticles for oil spills cleanup. …”
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8498
RNA methylated long non-coding RNAs as potential biomarkers for prognosis prediction in patients with lung adenocarcinoma: development of a risk assessment model
Published 2025-05-01“…This study aimed to develop a lncRNA-based risk assessment model based on RNA methylation to evaluate the prognosis of patients with LUAD. Method The TCGA-LUAD dataset consisted of 524 primary tumor samples and 59 normal samples, and the validation set (GSE3121011), which included 246 patients with LUAD, was used for this analysis.Pearson’s correlation analysis was used to identify lncRNAs associated with RNA methylation in LUAD. …”
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8499
Ratiometric fluorescence sensor for Cu2+ detection based on opposite responses of two fluorescence reagents to SBA-15 substrate
Published 2025-07-01“…Additionally, the developed method could be applied to the efficient quantification of Cu2+ in practical samples. …”
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8500
BREEDING OF TRITICALE WITH WHEAT TYPE OF GRAIN
Published 2018-06-01“…The variety ‘Khleborob’ was developed by the method of intervarietal hybridization within Triticale and the double individual selection in the hybrid population (Fahad-3/Erizo-15)/Mudrets// 98-115т3. …”
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