Opioid-use disorder and reported pain after spine surgery: Risk-group patterns in cognitive-appraisal processes in a longitudinal cohort study by Carolyn E Schwartz, ScD, Katrina Borowiec, MA, Bruce D Rapkin, PhD, Joel A Finkelstein, MD, MSc, FRCS(C), Tai Sutherland, BA, Olivia B Caan, BA, MS, Richard L Skolasky, ScD

“…This study examined cognitive-appraisal processes as potential moderators of OUD-risk, after adjusting for demographic and clinical factors. Methods: This longitudinal cohort study included 342 adults undergoing surgical treatment for a back/leg problem, neck/arm/shoulder problem, or spinal deformity at a United States academic medical center. …”
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Identifying locally actionable strategies to increase participant acceptability and feasibility to participate in Phase I cancer clinical trials by Stephanie A. S. Staras, Easton N. Wollney, Lisa E. Emerson, Natalie Silver, Peter T. Dziegielewski, Marta D. Hansen, Gabriela Sanchez, Dalila D'Ingeo, Versie Johnson‐Mallard, Rolf Renne, Kristianna Fredenburg, Michael Gutter, Kendra Zamojski, Carla Vandeweerd, Carma L. Bylund

“…In preparation for recruitment to a Phase I recurrent head and neck cancer (HNC) trial, we assessed perceived barriers to participation or referral and suggestions for recruitment among people with HNC and community physicians (oncologist, otolaryngologist or surgeon). Methods Between December 2020 and February 2022, we conducted a qualitative needs assessment via semistructured interviews with a race and ethnicity‐stratified sample of people with HNC (n = 30: 12 non‐Hispanic White, 9 non‐Hispanic African American, 8 Hispanic and 1 non‐Hispanic Pacific Islander) and community physicians (n = 16) within the University of Florida Health Cancer Center catchment area. …”
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Clinical genomic profiling to identify actionable alterations for very early relapsed triple-negative breast cancer patients in the Chinese population by Liye Wang, Qinglian Zhai, Qianyi Lu, Kaping Lee, Qiufan Zheng, Ruoxi Hong, Shusen Wang

“…Comprehensive genomic profiling helps to explore the clinically relevant genomic alterations (CRGAs) and potential therapeutic targets in very-early-relapsed TNBC patients.Methods Formalin-fixed paraffin-embedded (FFPE) tumour tissue specimens from 23 patients with very-early-relapsed TNBC and 13 patients with disease-free survival (DFS) more than 36 months were tested by FoundationOne CDx (F1CDx) in 324 genes and select gene rearrangements, along with genomic signatures including microsatellite instability (MSI) and tumour mutational burden (TMB).Results In total, 137 CRGAs were detected in the 23 very-early-relapsed TNBC patients, averaging six alterations per sample. …”
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The study of platelet reaction on a-C:H:SiOx coatings obtained via plasma enhanced chemical vapor deposition with bipolar bias voltage by M. O. Zhulkov, A. S. Grenadyorov, D. S. Korneev, H. A. Agaeva, A. M. Chernyavsky, I. A. Khlusov

“…To study platelet adhesion to a-C:H:SiOx film on titanium in an in vitro experiment to evaluate its antithrombogenic potential.Materials and methods. …”
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Kollegiale Online-Fallberatung in inklusiv arbeitenden Lehrkräfteteams – Erste Ergebnisse aus dem Belebt-Projekt zum Beanspruchungserleben und zu sozialen Ressourcen by Rebecca Baumann, Victoria Wiederseiner, Vanessa Jandl, Sabine Martschinke, Astrid Rank, Barbara E. Meyer, Birte Oetjen

“…Although caution is warranted due to small sample size, the results offer preliminary indications of a potential reinforcement of selected resources through participation in peer case consultation, along with a high level of acceptance for the consultation method, also or especially in the online format …”
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Dreams and Nightmares in Early Pregnancy: A Comparative Study with a Control Group by Scarpelli S, Spinoni M, Gorgoni M, Lasaponara S, Ciolli P, Rech F, Di Muzio M, Med C, Di Pasquale Benedetti I, Grano C, De Gennaro L

“…Serena Scarpelli,1,2 Marta Spinoni,1 Maurizio Gorgoni,1,2 Stefano Lasaponara,1 Paola Ciolli,3 Francesco Rech,3 Marco Di Muzio,4 Carlotta Med,1 Ilaria Di Pasquale Benedetti,1 Caterina Grano,1,* Luigi De Gennaro1,* 1Department of Psychology, Sapienza University of Rome, Rome, Italy; 2Body and Action Lab, IRCCS Fondazione Santa Lucia, Rome, Italy; 3Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; 4Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy*These authors contributed equally to this workCorrespondence: Serena Scarpelli, Department of Psychology, Sapienza University of Rome, Via dei Marsi 78, Rome, 00185, Italy, Email serena.scarpelli@uniroma1.itPurpose: This study investigated dream characteristics in women during the first trimester of pregnancy compared to a group of non-pregnant women, aiming to identify variables associated with the observed differences.Participants and Method: A sample of 100 pregnant women in their first trimester was compared to a control group of 100 age-matched non-pregnant women. …”
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Extracting Multifaceted Characteristics of Patients With Chronic Disease Comorbidity: Framework Development Using Large Language Models by Junyan Zhang, Junchen Zhou, Liqin Zhou, Zhichao Ba

“…However, the current methods for extracting such information are complex, time-consuming, and prone to errors. …”
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Psychological symptoms in perimenarcheal adolescents: association with PCOS risk factors by Heidi Vanden Brink, Heidi Vanden Brink, Kathleen C. McCormick, Marla E. Lujan, Jane Chang, Lisa Ipp, Erika L. Mudrak, Anisah Alladeen, Hannah Lamar, Joy Y. Kim, Joy Y. Kim, Jane Mendle

“…Adolescents at high risk for progression to PCOS may already experience psychological vulnerabilities prior to a clinical diagnosis or full manifestation of PCOS. …”
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Public perception of COVID-19 in Saudi Arabia during the Omicron wave: recommendations for policy improvement by Mohammed J. Almalki, Amani A. Alotaibi, Abdulrahman M. Jabour, Ali Elamin, Wafa A Hetany, Hamza Abdullah M. Adam, Hassan N Moafa, Ahmed S. Alamer, Anwar Alsharif, Sami M. Almalki

“…This study investigates Saudi citizens’ perceptions of COVID-19 during the Omicron wave.MethodsWe conducted a cross-sectional study using an online survey and a convenience sample of 746 participants. …”
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Age‐specific all‐cause mortality rates among adolescents and youth living with and without HIV: Evidence from a cohort study in South Africa by Siyanai Zhou, Elona Toska, Bulelani Gwampi, Leigh F. Johnson, Janke Tolmay, Wylene Saal, Zea Leon, Lucia Knight, Lucie Cluver

“…We lack granular (age‐ and sex‐disaggregated) data on mortality among ALHIV, hence, this study aims to assess all‐cause mortality among ALHIV in a low‐resource setting. Methods All adolescents ever initiated on antiretroviral treatment (ART, N = 1107) and their HIV‐negative peers (N = 456) aged 10–19 years, recruited as part of the Mzantsi Wakho study cohort, were followed up between 2014 and 2022 (yielding 12,427.7 person‐years of follow‐up). …”
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The impact of the SKILLZ intervention on sexual and reproductive health empowerment among Zambian adolescent girls and young women: results of a cluster randomized controlled trial by Lila A. Sheira, Chama Mulubwa, Calvin Chiu, Jenala Chipungu, Chelsea Coakley, Helene Smith, Ushma D. Upadhyay, Chansa Chilambe, Besa Chibwe, Jake M. Pry, Boyd Mkandawire, Maggie Musonda, Carolyn Bolton Moore, Jenny Liu

“…Abstract Background Zambian adolescent girls and young women (AGYW, age 15–24) experience a disproportionate burden of HIV and unintended pregnancy. …”
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Intratumoral STING agonist reverses immune evasion in PD-(L)1-refractory Merkel cell carcinoma: mechanistic insights from detailed biomarker analyses by Shailender Bhatia, Paul Nghiem, Rima Kulikauskas, Candice Church, David M Koelle, Lisa Tachiki, Kimberly Smythe, Thomas Pulliam, Shira Tabachnick-Cherny, Saumya Jani, Peter H Goff, Rashmi Bhakuni, Brandon W Seaton

“…We report detailed biomarker analyses in a patient with anti-PD-L1 refractory, Merkel cell polyomavirus (MCPyV)-positive, metastatic Merkel cell carcinoma (MCC) who was treated with an intratumoral (IT) STING agonist (ADU-S100) plus intravenous anti-PD-1 antibody (spartalizumab) and experienced a durable objective response with regression of both injected and non-injected lesions.Methods We analyzed pretreatment and post-treatment tumor and peripheral blood samples from our patient with single-cell RNA sequencing, 30-parameter flow cytometry, T cell receptor sequencing, and multiplexed immunohistochemistry. …”
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The impact of nationality status and place of residency on health-related social needs and quality of life among Palestinian Refugees in Jordan by Hamza Alduraidi, Rahaf Issam Abu Zayid, Noor Mahmoud Jaber, Bassam Saleh Hijazi, Sa'ed Radwan Khamis, Hasan Fahed Awad, Marah Al-Khateeb, Saif alnour Mahmoud Aldhirat, Ahmad Amjed Toubasi

“…This study aims to assess differences in health-related social needs and quality of life among different Palestinian refugee communities in Jordan, based on their nationality status and camp residency. Methods: A descriptive, comparative, cross-sectional design was used to measure health-related social needs (using the Accountable Health Communities Health-related Social Needs (AHCHRSN) screening tool) and quality of life (using the World Health Organization Quality of Life BREF (WHOQOL-BREF)) among a sample of 236 adult Palestinian refugees in three contexts; (off-camp, in-camp citizens, and in-camp non-citizens) in Jordan. …”
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Understanding motives for illicit medicinal cannabis use: an exploratory analysis in a medical cannabis program by Carter Reeves, Lirit Franks, A. Taylor Kelley, Michael Incze, Adam J. Gordon, Ziji Yu, Eden Flake, Gerald Cochran

“…Identifying barriers and contributors to MC use and motives for IMC use can promote safety, improve program design, and inform future research efforts. Methods This exploratory analysis utilized baseline survey data from a convenience sample-based prospective cohort evaluation of newly registered (< 6 months) adult participants in Utah’s MC program who had been diagnosed with chronic pain, post-traumatic stress disorder, and/or cancer. …”
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Dental caries prevalence among Type 1 diabetes mellitus (T1DM) 6- to 12-year-old children in Riyadh, Kingdom of Saudi Arabia compared to non-diabetic children by Abid Hamoud Al-Badr, Albandary Hassan AlJameel, Hassan Suliman Halawany, Yousra Hussein Al-Jazairy, Mohamad Khalid Alhadlaq, Nassr Saleh Al-Maflehi, Jehan Adnan Al-Sharif, Vimal Jacob, Nimmi Abraham

“…Objective: The aim of this study was to compare the prevalence of dental caries among groups of 6–12-year-old children with and without Type 1 diabetes mellitus (T1DM) in Riyadh, Saudi Arabia, taking into account oral health behaviour, diet, and salivary parameters. Methods: The study was designed as a comparable study of dental caries experience between T1DM and non-diabetic groups of children. …”
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Study on the prevalence of traditional smoking and the use of modern electronic nicotine delivery systems in different age groups of patients with ischemic heart disease by O. O. Zhurba, V. V. Lazoryshynets, A. V. Rudenko, K. V. Rudenko

“…The aim to define the frequency of traditional smoking and electronic cigarette use among coronary heart disease (CHD) patients of different age groups. Materials and methods. The study included patients with CHD who underwent off-pump coronary artery bypass surgery (n = 3674). …”
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Cerebral blood flow increases in idiopathic generalized epilepsy and its relationship with mood dysfunction by Yun Lien, Ayushe A. Sharma, William R. Willoughby, Anna Moyana, Jennifer Pilkington, Ja’ Kaiya Bryant, Adam M. Goodman, Goutham Selladurai, Lawrence W. Ver Hoef, Jerzy P. Szaflarski, Jane B. Allendorfer

“…Abstract Objective To investigate the relationship between cerebral blood flow (CBF), seizure control, and mood regulation in idiopathic generalized epilepsy (IGE), we hypothesized that higher CBF in mood‐regulating regions would be associated with greater mood disturbance, particularly in patients with poor seizure control. Methods Twenty‐three patients with IGE (13 female) and 19 healthy controls (HCs; 9 female) completed 3T MRI. …”
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Rationale and methodology of a multicentric prospective cohort study on ‘Longitudinal Effects of Air Pollution Exposure on Adolescent Lungs (APEAL)’ in urban India: APEAL protocol... by George D’Souza, Anant Mohan, Padukudru Anand Mahesh, Amruta Nori-Sarma, Harish C Phuleria, Gregory Wellenius, Twinkle Agrawal, Rajesh Thimmulappa, Biligere Siddaiah Jayaraj, Minu Rose Mani, Swapnali Patil, Priya Samdarshi

“…While Indian cities experience much higher pollution levels, the impact on lung development in Indian children remains unclear. …”
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Gender Differences in Predictors of Physical Functioning Limitations Among the Elderly Population in Serbia: A Population-Based Modeling Study by Dejan Nikolic, Natasa Mujovic, Milena Santric-Milicevic, Sindi Mitrovic, Nevena Krstic, Ana Radic, Diana Radovic, Ardak Nurbakyt, Dinara Sukenova, Milena Kostadinovic

“…This study aimed to assess self-perceived general health and related health characteristics among the elderly population in Serbia, with a focus on varying degrees of functional limitations, as well as to analyze the predictors of physical functioning limitations in relation to gender. <i>Materials and Methods:</i> This population-based modeling study included a representative sample of 3540 elderly individuals aged above 65 years from Serbia. …”
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Preferences for Mobile App Features to Support People Living With Chronic Heart Diseases: Discrete Choice Study by Sumudu Avanthi Hewage, Sameera Senanayake, David Brain, Michelle J Allen, Steven M McPhail, William Parsonage, Tomos Walters, Sanjeewa Kularatna

“…ObjectivesThis study quantifies the preferences of individuals with chronic heart disease (CHD) for features of a mobile health app to self-navigate their disease condition. MethodsWe conducted an unlabeled web-based choice survey among adults older than 18 years with CHD living in Australia, recruited via a web-based survey platform. …”
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